Esomeprazole User Reviews & Ratings (Page 3)
Brand names: Nexium, Nexium 24HR, Nexium IV
Esomeprazole has an average rating of 6.1 out of 10 from a total of 274 reviews on Drugs.com. 49% of reviewers reported a positive experience, while 34% reported a negative experience.
Reviews for Esomeprazole
- Bil...
- Taken for less than 1 month
- December 29, 2019
For GERD "So I got acid reflux to the point where it woke me up at night. I got the pills Nexium to help. It helped for two days before I noticed I was constipated and extremely gassy, making it feel like I was passing a kidney stone or had a hernia while it was just the gas build-up in my body. The next day, it felt so much worse, and I also got pukey, to the point where I couldn't sleep and just wanted to purge my body of Nexium."
- Anonymous
- June 3, 2015
For GERD "I was prescribed Nexium after 4 months of trying every other prescription med out there, following 4 months of severe GERD/silent reflux symptoms. Within the first 2 days of taking Nexium, the lump feeling in my throat started to go away. I am taking 40 mg of the TEVA generic Nexium, and so far, I feel way better. Hopefully it lasts. I was on Dexilant before, 60 mg once a day, and it gave me about 50% symptom relief. Nexium is the best PPI I have tried for sure, and I would recommend it to anyone."
Frequently asked questions
- Jam...
- Taken for less than 1 month
- September 29, 2021
For GERD "I couldn't figure out what was going on with me - I had extreme apathy (apathy is when you lack motivation to do anything or just don't care about what's going on around you), which is very unlike my character. I was struggling with GERD, just short-term for unknown reasons, so I decided to try the 14-day Nexium course of treatment. I stopped at day 11. I could not stand the mental health effects it had on me. It brought back my anxiety and panic attacks full force. Why is this not discussed more often? No, none of you are crazy. We can't all have the same issues and be brushed off by the medical profession. I am a registered nurse and will never endorse this medication."
- Str...
- April 17, 2017
For GERD "Had some absolutely crazy bad stomach pains that felt like I was having a heart attack and was hospitalized a couple of times in the lead-up to trying this drug. Have always had reflux but always kind of ignored it. Sometimes I'd wake up choking as I'd refluxed into my lungs while asleep. First I started this drug as prescribed, taking 40 mg every day, and it instantly took away problems. But being a strong believer in not taking drugs if possible, I stopped taking it every day. Now I only take it when I actually feel burning, which might only be once or twice a month. And within minutes, I feel better. Not saying to follow my lead, but this works for me. I think using this drug as I am and getting the relief I'm getting is absolutely wonderful."
Are you taking this medicine?
Your review helps others make informed decisions.- Edd...
- November 23, 2017
For GERD "Had GERD for 3 weeks, couldn't even sleep at night. So I decided to try Nexium 24HR after a bit of research. I've been on it now for 5 days, and for me, it works wonders. Now I can even eat, got my appetite back. All I can say after reading a lot of reviews, pros and cons, it really helped me, but to each his or her own. I had nothing to lose."
- Nat...
- Taken for less than 1 month
- July 22, 2019
For GERD "I’ve been suffering from GERD since January. After being in the hospital, I was prescribed 40 mg Nexium. It worked, however, I had terrible side effects such as severe fatigue, muscle weakness, and mild hallucinations because of exhaustion. I then decided to take the natural road, which helped to a point, however, I was still suffering quite intensely. A month ago, I decided to succumb to my fear of trying the OTC Nexium. By day 4, I was better, by week two, I was clear of all of my symptoms. I feel great, happy, energetic, and grateful. Nothing more painful than watching your friends enjoy foods and drinks you can’t eat. I never thought the pain would end, and I’m so happy that I’m well again. I’m still on a low acidic diet because my aim is to come off the medication. I still think it’s important to find the root cause of your GERD and learn natural ways to heal your body. For now, Nexium has saved me."
- BKa...
- August 7, 2015
For Erosive Esophagitis "I was on Aciphex for 4-5 years, but the expense of it shifted me over to Nexium. I have now been taking 20 mg Nexium for 4 years and have not had a GERD attack in years. My concerns are now that you can buy it OTC, I am concerned it will not be strong enough? And secondly, why is it that most nutritionists and holistic doctors insist that these acid-controlling pills are the worst thing to take for your body? I tried not taking it for 2 months and immediately had an attack, which is horrible. Can someone answer my concerns, please?"
- Pin...
- September 13, 2019
For GERD "In 2014, I was diagnosed with H. Pylori, which was eradicated successfully. In 2019, diagnosed with chronic gastritis, I was prescribed Nexium 40 mg for the first month and 20 mg for five months. It worked so well that I started eating things I was not able to eat before. I was so happy until I developed side effects that I never thought were from Nexium. They were stomach ache, diarrhea, constant nausea feeling, pain in my back and between shoulder blades, headache that would come on from little sound, like someone coughing, and extreme fatigue. When my periods started, I had nightmare cramping, I was vomiting, runny tummy all day, and excruciating pain. I couldn't sit, lie down, or walk. I was literally rolling on the floor with pain, and I never suffered from period pains before. I decided to go off it. I am on my first day. The stomach pain and the shoulder pain subsided, the fatigue almost completely gone. I had little diarrhea and tummy ache. I am hoping all this will be gone and will go back to normal. PPIs are a bittersweet pill."
- gra...
- Taken for 2 to 5 years
- May 5, 2013
For Barrett's Esophagus "I was on Nexium for more than 4 years, and the Barrett's esophagus that I have has been stable. I believe that Nexium has healing properties, but change in diet has to come with it. My husband's insurance now refuses to pay for it because it is supposedly for short term."
- For...
- Taken for less than 1 month
- May 30, 2017
For GERD "I have taken other reflux medicine. My gastroenterologist suggested I try this one. This was a colossal mistake. I'll try to tell you what happened yesterday, and you can judge for yourself. So I woke up the next day after taking it the previous night and felt awful. I felt like I was going crazy, and my brain was a little bit messed up. I couldn't think straight. I felt like I wanted to crawl out of my skin. My fingertips were hurting. My muscles were aching. I had a hard time talking. The side effects were genuinely horrible, mentally and physically. It was one of the worst days I've had in a long time. I didn't take it after I went to bed, and the next day I woke up feeling fine. Avoid this drug."
- Tam...
- Taken for less than 1 month
- September 5, 2022
For GERD "I only got prescribed Nexium yesterday due to intense chest pressure/heartburn caused by the bacteria H. pylori. I took 2 doses at the hospital, one when I got home and one when I woke up as instructed by the doctor. The side effects are scary. I can’t get out of bed. I have zero energy. I keep throwing up. I have insane chills, I am either freezing or hot. And the worst of them all…ANXIETY. I can’t even catch my breath. This is the worst I’ve almost ever felt. I called the doctor, and he said it’s possible that the pill is doing this and to take Omerpradex instead. I hope this feeling will go away fast because I have never felt so ill before!!!"
- Anonymous
- November 18, 2012
For GERD "I've had GERD since I was 14, and I had tried all sorts of OTC and prescription medicines. Most of them worked okay, but I would still have to pop a few Tums before I went to bed. After starting on Nexium, I feel great! I've yet to have any signs of heartburn, and I haven't had any side effects. This is the most expensive prescription I've had, but the cost is well worth it."
- Hsp...
- Taken for 1 to 2 years
- August 18, 2019
For Barrett's Esophagus "When I first started taking Nexium for Barrett’s esophagus, everything seemed fine. Then, after having a gastric bleed, in which they found cancer cells, I went through 6 weeks of radiation and chemo treatments. The good news is the cancer's gone. But during that time, the doctor doubled my dose of Nexium to 80 mg. I take it as 40 mg twice a day. So, after 6 months of Nexium treatment, I mysteriously had a spine fracture, recurrent sinus infections, severe stomach pain, and inflammation. I couldn’t figure out what was happening, so I researched Nexium and found it can weaken the bones and cause spine fractures, also contribute to stomach distress and sinus headaches, and so many other things it’s hard to even imagine. Now I know why the FDA has put out so many warnings about this drug. My question is why don’t they ban it. I’m seeing my doctor about getting off this horrible drug."
- Anonymous
- Taken for less than 1 month
- June 22, 2012
For GERD "I started with really bad nausea and sick to my stomach. When I went to my GI doctor, I was diagnosed with duodenitis and chronic gastritis. I was so sick with nausea twenty-four seven, I literally felt like I was going to die. I actually told my GI to prescribe me Nexium 40 mg. My GI was hesitant, but I insisted. I took it for about a month and a half, and on my second endoscopy, my chronic gastritis had gone down to mild gastritis, and the nausea is almost gone. Nexium really helped me. I don't know about the side effects since I took it at night. But the nausea was still persistent, it's just now going away. I can tell you this is one of the best medicines. Stops the acid production by 95 percent-something I had to find out on my own. Good luck."
- Anonymous
- Taken for 10 years or more
- April 25, 2018
For GERD "I have been taking Nexium for over 14 years now and cannot speak highly enough of this drug. Before Nexium, I was eating Quikzee like they were lollies. Now, one 20mg dose all this time daily, with the only side effect being gas in the mornings. This has been a wonder drug for me."
- Jan...
- Taken for less than 1 month
- January 15, 2019
For GERD "I was taking pantoprazole in October, and it helped with the acid reflux. After taking it for a week, I started having burning in my arm, shoulder, legs, and stomach. But like a crazy person, I kept taking it. I started having anxiety, and I started losing weight - 18 pounds within one month. But eventually, I got myself off of it and started taking Nexium, and it did not work either, I started losing patches of my hair. I started researching both medications, and they both were in the worst pill list. I’m now taking Zantac 150, hopefully, this will work."
- Mar...
- December 29, 2016
For GERD "Taking for the first time, started 6 days ago, and it is not helping and seems to be making the condition worse. Lots of swallowing, stomach noises, dry cough, and lack of energy. Disappointed. Is it safe to just discontinue use?"
- Rio...
- Taken for 5 to 10 years
- May 8, 2018
For GERD "Asthma physician prescribed Nexium 40 mg for me after I needed to use my asthma inhaler 4 times a day. Over time, I was diagnosed with long-standing hiatal hernia and GERD. I continue to use Nexium to manage my breakthrough reflux, and the result has been wonderful for me, save for occasional nuisance bloating. Thanks."
- Mic...
- Taken for 1 to 2 years
- May 12, 2020
For GERD "I was prescribed the generic brand of Nexium, it worked once I was taking it properly. I thought I could stop after a while, but I would truly not be able to eat or sleep through the night if I was not taking this pill. Though I take it daily, on rare occasions I have an episode of running to the bathroom to throw up at night. I have noticed no side effects and have been taking it for a year or a little longer."
- Eso...
- Taken for less than 1 month
- June 28, 2022
For GERD "Omg, I am so glad I found this website!! I took Nexium 20mg 24hr for 2 weeks, then my GI put me on 40mg, and after taking it for 1 week, I thought I was going crazy with all these horrible side effects such as anxiety, muscle twitches, bloating, belching, insomnia, heart palpitations, and much more!! Ended up in the ER, did an ultrasound and bloodwork, and nothing came up, so they must have thought I was faking it. It raises my blood pressure, makes me so fatigued that some days I couldn’t even get out of bed. My mouth and eyes were so dry, brain fog, and confusion…. Just HORRIBLE!! I’m so glad I went on here and found all these reviews, I will stop taking it!"
- Bat...
- Taken for less than 1 month
- November 12, 2019
For GERD "After a couple of hours of taking Nexium, I began to feel nauseous, another hour or so later, I vomited. Then the diarrhea started. Watery and urgent, I couldn't leave the house. I have tried this medicine several times, and every time I have had the same reaction. It is the worst medicine I have ever been prescribed, and I am going to destroy the ones I have left. The dosage I was prescribed was 40 mg, and this may well be too much, but I will not try to take it again."
- Ele...
- March 6, 2010
For GERD "Diagnosed with acid hitting my throat (LPR). Have a small stomach hernia that is not allowing sphincter to close. It was a rough 6 months till I was diagnosed. 3 doctors insisted I had allergies. Found another doctor that finally advised I had 'silent acid reflux.' Have cut out all the usual foods that cause more acid, but in my case, my ears hurt (they tell me you have lots of nerves through the throat that go up to the ears and sinuses). Symptoms are: burning ears, flaring up through the sinuses, pain in the back of the neck up through the top of the back of my head. Have been on Nexium for 3 months. It helped, but flaring returns 10-50%. Have come off Nexium to do the tests on how my GI is working. Nexium helped, but lots of side effects."
- Ber...
- Taken for 5 to 10 years
- January 8, 2020
For GERD "I started taking Nexium in my teens (20 years ago) for persistent acid reflux. At the time, it relieved the nausea I was experiencing, and I used it on and off for about 7 years before stopping completely. One thing I did suffer with during those 7 years was chronic diarrhea, which at the time was diagnosed as IBS. After I stopped Nexium completely, the pattern of chronic diarrhea went away. That is until this past year when I was re-prescribed Nexium to deal with heartburn. When it works, Nexium is great, and I have no problem tolerating the side effects to gain what relief I can from reflux. However, I've noticed this time around it's working very slowly to alleviate my heartburn pain, if it alleviates it at all, and it's made dealing with any side effects increasingly frustrating."
- hpy...
- December 1, 2009
For Helicobacter Pylori Infection "Being on this medicine for the first 5 days was hard, felt sicker than ever with symptoms of mild diarrhea, some hives, worst nausea, fatigue. This started to improve day 6. After being on it for a week, am almost back to normal. Felt like the drugs had to work on the H. Pylori, then the body had to work on getting the drug out of the body."
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Patient resources
- Esomeprazole drug information
- Esomeprazole injection
- Esomeprazole Delayed-Release Tablets
- Esomeprazole Delayed-Release Capsules
- Esomeprazole Powder for Suspension
Other brands
Nexium, Nexium 24HR, Nexium IV
Professional resources
- Esomeprazole monograph
- Esomeprazole (FDA)
- Esomeprazole Capsules (FDA)
- Esomeprazole Injection (FDA)
- Esomeprazole ODT (FDA)
For Barrett's Esophagus "I’ve had Barrett's esophagus for ten years, and of all the meds prescribed, Nexium for Barrett's esophagus has been the only one that saves me from horrible acid reflux. When insurance refused to pay any longer, I attempted to treat my disease myself with many supplements for GERD. I ended up with a severely inflamed esophagus and a related stricture the doctor dilated at the time of endoscopy. He informed me I must return to Nexium with no substitutes indefinitely, as it is protecting me from getting cancer of the esophagus due to having Barrett's. The inflammation healed right away once I was back on Nexium."