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Esomeprazole and Dizziness: What Users Say

Brand names: Nexium, Nexium 24HR, Nexium IV

Dizziness: mentioned by 17 users (6.2%)

Based on user experiences from 274 Esomeprazole reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 12.8%
diarrhea 9.9%
nausea 9.9%
headaches 9.1%
fatigue 6.9%
dizziness 6.2%
pain 5.5%
heart palpitations 5.1%
tremors 5.1%
chest pain 4.7%

Reviews for Esomeprazole

Commonly mentioned side effects
  • Kek...
  • Taken for 2 to 5 years
  • February 20, 2020

Esomeprazole for GERD "I have been on Nexium for four years for GERD and just recently stopped. I have recently come to realize that Nexium is no longer helping me and instead is creating a whole other set of problems such as low B12, intermittent low iron, upset stomach, dizziness, rash, etc. Now with studies showing dementia as another possible side effect, it's a drug I wouldn't recommend anyone be on. Honestly, do yourself a favor - if you have GERD like me, change your diet, exercise a bit more, don't eat after six, and have a Tums for heartburn instead of using this garbage. Plus, a three-month supply is $442.00 where I live. NEVER again. Big pharma is just a crime."

1 / 10
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  • Yos...
  • Taken for 1 to 6 months
  • February 20, 2020

Esomeprazole for GERD "I feel much better, thanks to this website. I have been on Nexium for 2 months and started to develop brain fog, dizziness, and involuntary muscle twitches. I am glad to read I'm not the only one. I will be weaning myself off of this medication. Great for acid but not worth it. Thanks!"

10 / 10
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97 Report
  • jay...
  • Taken for 1 to 6 months
  • December 30, 2020

Esomeprazole for GERD "I bought Nexium after the Zantac warning. It helped with reflux but caused constipation fairly quickly. Next, I noticed dizziness, then feelings of nausea, followed by extreme tiredness during the day but insomnia, causing me to wake in the early hours and be unable to fall asleep again. I became extremely depressed and lost interest in everything. The final straw was noticing that my legs have started to swell and feel tight, and my feet are tingling and uncomfortable when I want to relax. The first few symptoms I could live with, but the swelling and twitching of my feet and legs is not acceptable, neither is the aching I am experiencing. I am concerned about this to the extent I will be contacting my doctor. I will not be taking any more Nexium, I will try to control acid with diet from now on."

1 / 10
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Frequently asked questions

  • MEa...
  • Taken for 1 to 6 months
  • January 15, 2020

Esomeprazole for GERD "I had been taking this medication, Nexium, for 4 months. I didn’t realize it at first, but it slowly sucked away my energy. Near the end of the 4 months, I began to feel nauseous and dizzy, with pain in my back. I had labs done and am borderline anemic, low potassium, and kidney function is no longer optimal. I stopped the drug immediately and started to feel better-aside from the return of my gastritis. Three days ago, I began taking it again: same symptoms, except this time with diarrhea, too. Make sure your vitamins and electrolytes are measured before and during use of this drug! It has been awful for me."

1 / 10
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  • Hor...
  • Taken for 1 to 6 months
  • November 16, 2021

Esomeprazole for GERD "I have been taking this medication for the past 4 months, 20 mg but recently up to 40 mg. I wanted to stop taking it a while ago as I felt it wasn’t working, but the specialist insists on taking it. Since taking 40 mg, I have felt so nauseous, have headaches, and feel so dizzy. Since reading these reviews, I have only just put 2 and 2 together. This drug is the cause of all the weird symptoms I’ve been experiencing for the past few months. I’ve had multiple doctor visits due to having bad palpitations, chest tightness, and breathlessness very regularly for the past few months. Had heart ultrasound and multiple ECGs, doctors have said my heart is fine and it’s my anxiety, yet it has nothing to do with my anxiety. This is the best I have ever felt mentally. These symptoms just hit me randomly. Before this drug, I didn’t feel like this. It’s truly scary thinking about all the symptoms these drugs cause and doctors insist it’s fine. I’m going to stop taking this ASAP. NEVER AGAIN!"

1 / 10
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  • Max...
  • Taken for less than 1 month
  • April 15, 2021

Esomeprazole "I took Nexium 40 mg for 3 weeks. At the beginning, it was fine, my acid reflux was fixed, but side effects were terrible, such as depression, anxiety, tremor, diarrhea, back pain, and general feeling of sickness. Dizziness during the day. This is my 3rd day off from Nexium 40 mg, back pain is gone, but still feeling dizzy from time to time. Does anyone know how long these side effects last? Thank you."

1 / 10
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  • Ger...
  • Taken for less than 1 month
  • July 10, 2021

Esomeprazole for GERD "I took this 20 mg twice a day as recommended by my doctor, and within 4 days I had palpitations, insomnia, extreme anxiety, dizziness, nausea, and pins and needles in my neck and legs. Worse was at night when trying to lie down, when there would be pressure in my head and chest, and violent dizziness and nausea. I had two weeks of only sleeping 2 hours a night and peaked with 2 successive nights of no sleep and a visit to Accident & Emergency. Suddenly realized it was the tablets and stopped them, effects slowly going and sleeping at last."

1 / 10
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  • Bom...
  • July 27, 2021

Esomeprazole for GERD "I've been on over-the-counter Nexium 20 mg for 6 daily doses, as I hadn't been able to pick up my omeprazole prescription. My God, I thought I was dying! Massive panic attack yesterday, nausea, dizziness, and early morning insomnia, followed by crazy thoughts, diarrhea, and eye twitches. I still have waves of nausea, had no idea what it was until I visited these shared experiences. I'm off it now, and this review site has settled my nerves! This stuff is utterly toxic! Steer clear! Thank you all."

1 / 10
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  • Ari...
  • Taken for 1 to 6 months
  • June 14, 2022

For Gastritis/Duodenitis "Like anyone experiencing these symptoms would think they were having a heart attack or something, and so I did. I went straight to the ER and my ECG was totally normal. I did a battery of tests, including echocardiogram, ergometric test, Holter monitor, and none of them found anything. Clinically, I am healthy, without any heart problems. I suspected it was the medication two weeks ago when, on the days that I had to have blood drawn for the exams and had to fast, ironically I didn't feel any of the main symptoms, which would be extreme dizziness, extreme tiredness, and pain in the stomach, chest/arm/shoulder that decreased. Discovering this, I started looking for reviews about the drug and found this forum which confirmed my suspicions. 2nd part"

2 / 10
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  • Ari...
  • Taken for 1 to 6 months
  • June 14, 2022

For Gastritis/Duodenitis "In the first week that I stopped, on the second day the acid returned with everything. I managed to cope well because my diet was well controlled. The dizziness disappeared on the third day, and in the next weeks I only lived with the pain in the chest/arm/shoulder, and an increase in acidity, in addition to anxiety, and blood pressure still changed (this with two weeks without using). From time to time, I feel some pain in my stomach because I know that my gastritis and bulboduodenitis are still not completely cured for not completing the three months of treatment. The drug did help to improve the symptoms of my gastritis, but it made me extremely worse in many other aspects of my health. If you are experiencing the same symptoms that I am experiencing, please re-evaluate and see if you can avoid using this medication. Depending on the person, it can really give you several side effects. 3rd part"

2 / 10
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  • Ril...
  • Taken for 1 to 6 months
  • June 16, 2024

For Gastritis/Duodenitis "I had suspected gastritis after a stomach bug, with burning under my rib cage. The gastritis itself was causing me to feel shaky, and I had one episode of pounding heart and probably something of a panic attack. This happened right after diarrhea and me taking Pepto-Bismol. So, the doctor put me on esomeprazole 40 mg, and it quickly addressed the acid burning, and I do think it's helped me heal. However, I'm currently tapering off this after six weeks of use because I've been getting the anxious, lightheaded, dizzy nausea feelings described by others and they're getting to me. I've not yet had the rebound acid, hopefully, I won't. I just take a couple of Tums here and there. I'm just hoping and praying the dizzy, pre-fainting feelings go away soon. God bless all of you, take care of your guts!"

5 / 10
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  • Jam...
  • Taken for 1 to 6 months
  • September 16, 2021

For GERD "I have had a hiatus hernia for many years, but it hasn't caused that many problems until about two years ago. The doc prescribed me everything under the sun, including Omi, Panto, Lanso, and Esomeprazole. By far, the worst of these was Esomeprazole, I experienced all of the bad stuff that people have given reviews about. I stopped taking Esom for a while, but the heartburn kept coming back, so I went back on it yesterday. Big mistake! After two hours, I had delusions, lower right side back pain, bloating, shakes, headache, chest pain, diarrhea, dizziness, I felt like a heart attack was going to happen (anxiety). Believe me when I say this medicine is an absolute nightmare! It may be alright for a few people to cure their acid reflux, but you get a whole new set of problems with it, which is far worse. A lot of people are on this for more than 14 days via docs' prescriptions, that's like a death sentence! It is still being sold as a wonder drug online and in chemists and supermarkets as well! Steer clear!"

1 / 10
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  • Anonymous
  • January 31, 2012

Esomeprazole for GERD "It worked great but made me really dizzy. Has anyone experienced this?"

10 / 10
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79 Report
  • Jer...
  • February 17, 2011

Esomeprazole for GERD "After 3 days on Nexium, my reflux is completely gone. But I now have nausea, body aches, constant mild headache, rash, tiredness, dizziness, and worst-ever stomach cramps."

1 / 10
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  • Cow...
  • October 10, 2016

Esomeprazole for Barrett's Esophagus "Side effects are horrible. Fatigue, dizziness, foggy head, aching muscles, and burning toes."

6 / 10
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  • Mer...
  • Taken for less than 1 month
  • October 6, 2024

Esomeprazole for GERD "It worked, but I was dizzy almost all day, lightheaded, dry mouth, fatigue, heart palpitation, depressed eyes, a little blurry."

6 / 10
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  • gav...
  • Taken for less than 1 month
  • October 8, 2024

For GERD "After 3 days, felt relief. Day 4, felt itchy but passed after 12 hours. Day 5, dizzy, tired, no energy. Day 6, shakes in right hand for a while. Decided to stop taking them."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.