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Aciphex User Reviews & Ratings

Aciphex has an average rating of 9.2 out of 10 from a total of 54 reviews on Drugs.com. 92% of reviewers reported a positive experience, while 2% reported a negative experience.

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Reviews for Aciphex

  • Kgd...
  • Taken for 1 to 6 months
  • November 23, 2021

For GERD "Hoping my review might help someone. I have gastritis and went through about 4 different PPIs before I took this one because the others caused severe anxiety. Aciphex was the first med that helped and didn't cause a huge increase in anxiety. With this med in the morning and taking Remeron at night, I am now feeling much better. I also adjusted my diet significantly as well."

10 / 10
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42 Report
  • ROY...
  • November 2, 2019

For Barrett's Esophagus "I was diagnosed with Barrett's esophagus and GERD 19 years ago. My doctor put me on Aciphex, and it worked great. My next scope showed Barrett's was healed, but I was still taking Aciphex for GERD until insurance would no longer pay for it. I could not afford the atrocious cost of Aciphex and switched. I have tried all OTC, prescription Prilosec, and Prevacid. None have worked as well as Aciphex. I also have epilepsy and have to be mindful of drug interactions even with PPIs. It's really sad that pharmaceutical and insurance companies dictate to consumers what they can and can't take based on monetary greed. Who knows better than the consumer what is best and works best in treating their physical health and well-being."

10 / 10
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47 Report
  • Peo...
  • Taken for 10 years or more
  • November 14, 2020

For GERD "I have been taking brand-name Aciphex since probably the late 1990s. 20 mg/day magically disappeared my symptoms after all other PPIs and H2 blockers eventually failed. Then the price started to go up, so I celebrated the day the patent expired. Generic rabeprazole was a great disappointment, so we (my GI doc and I) kept writing letters to insurance so they would pay for the brand name. Eventually, the price went out of control, so we had to abandon that option. We found out that Eisai Ltd., the manufacturer of Aciphex, also manufactured the generic rabeprazole under the name of Pariet in Great Britain. This worked so far for the last couple of years, but I have to double the dose to 40 mg/day and combine it with 20 mg of famotidine. I read other reviews that indicate people had similar frustrating experiences when switching to generic rabeprazole. I wonder what makes that difference and why?"

9 / 10
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35 Report
  • Kev...
  • December 26, 2014

For GERD "I have tried every over-the-counter and prescription medicine for GERD that I can think of. Aciphex is the only one that has ever worked for me. I have suffered from GERD and other gastric issues for a long time, and I suffer when I run out of this medication. I love to eat...so...this helps."

10 / 10
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53 Report
  • you...
  • February 14, 2012

For GERD "Amazing medicine! I've had GERD for 14 years. I've been on Aciphex for 10 years. No other medicine has ever come close to touching how effective this is for me. When my insurance stopped paying for it, I tried Prevacid. It did not help me at all. I had to try it for two weeks, and if it failed to help, my insurance agreed to pay for Aciphex. That was the most miserable 2 weeks of my life. Constant burning reflux was all my days were filled with. I was so happy when I got to get back on Aciphex! I have no reflux symptoms whatsoever with it. If GERD is making your life miserable, give it a try!"

10 / 10
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58 Report

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  • drs...
  • Taken for 10 years or more
  • October 2, 2013

For GERD "Started years ago and got instant relief. Tried all other available meds with little results. Never had any side effects at all with Aciphex. My insurance doesn't like it, but I couldn't live without it."

10 / 10
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48 Report
  • The...
  • Taken for 2 to 5 years
  • October 16, 2015

For GERD "My insurance refuses to pay for it, saying Prilosec is just as good. NOT!!!!! I take 2 a day (180 for 3 months), and it would cost me almost $700 a month. I get it through Canada for $123 per 200, over 3 months vs. $2,000. Aciphex is not even comparable to any other: Zantac, all of them. Good luck to you."

10 / 10
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38 Report
  • kat...
  • December 14, 2008

For GERD "I have severe acid reflux and tried numerous medications - Tagamet, Nexium, and many over-the-counter medicines. Aciphex is the only medication that has helped. I've taken it for 8 years with no side effects."

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58 Report
  • Anonymous
  • February 23, 2012

For GERD "I've been taking Aciphex since 2001, and it has worked wonders on my GERD. Before I retired from active duty in 2003, one doctor switched me to another brand. Next thing you know, I was in the hospital with extreme chest pain- all caused by GERD. I went back on the Aciphex and have been comfortable ever since."

10 / 10
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48 Report
  • kat...
  • February 23, 2015

For GERD "I have had GERD for years. I tried everything available, and nothing helped until my doctor prescribed Aciphex. No more pain. It is the best thing on the market. I do not know why it is not over the counter. My insurance has tried to have my doctor switch me to a less expensive medicine, but they didn't work, and I had to pay the higher copay for Aciphex. It is a Godsend. I do wish it was cheaper and over the counter."

10 / 10
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38 Report
  • NAN...
  • Taken for 10 years or more
  • December 21, 2018

For GERD "I've had GERD for 20+ years. Tried all of the medications but seemed to build up resistance to them, and they would no longer work after several months. ACIPHEX is the only one that worked consistently, however, insurance wouldn't pay for it. My doctor wrote several letters and finally got it approved. I am now on Medicare, and it is not on an approved list where I can get it. It is truly a miracle drug and has worked for me consistently. I, too, don't know why there is not a generic form or why it is not more affordable. I would give this a 10 out of 10."

10 / 10
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25 Report
  • Nav...
  • July 5, 2017

For Barrett's Esophagus "Have taken Aciphex for 20 years until insurance companies refused to cover this and all PPI drugs. I have suffered ever since. Aciphex 3 years ago cost $20.00 per 30 tablets. Then in 2015, this medication increased to $378.00 per 30 tablets. Now my insurance company will not cover this drug. I am on my own. No PPI prescription drugs anymore. So, for every action, there is an opposite and equal reaction. Scopes yearly, which will cost my insurance company more than a year of this drug. Idiots. Nothing works except Aciphex 20 mg."

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29 Report
  • Anonymous
  • April 3, 2008

For GERD "Aciphex was a true dream come true for me. I've suffered from severe reflux for 3 years now, because of a hiatal hernia, and this is the first and only thing that has completely stopped the reflux and pain!!!!"

10 / 10
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52 Report
  • saw...
  • September 15, 2007

For Stomach Ulcer "I have been using Aciphex for years. First in conjunction with other meds to treat a problem with stomach ulcers and, then and now, to control acid reflux. I have always had great success using this medication. Recently, my physician has taken me from a daily dose to an 'as needed' dosage."

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53 Report
  • Anonymous
  • December 21, 2010

For Barrett's Esophagus "Works well, can manage most foods without any problems. Note that this medicine does promote food moving through one's system more quickly, so frequent bowel movements and loose stool may be an issue for some."

9 / 10
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40 Report
  • pau...
  • February 20, 2009

For GERD "I take AcipHex every morning to control my heartburn symptoms. After I eat breakfast, I get heartburn from the coffee and juice. I take AcipHex after breakfast, and I always find it works really fast to make my heartburn go away. Even when I go to bed at night, I don't have heartburn. The other best thing is that it's a tiny pill, and it's so easy to swallow. Half the time, I don't even have to have something to drink."

10 / 10
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44 Report
  • Tam...
  • July 7, 2010

For GERD "I have had GERD and GERD-like issues since the age of 12. I have been put on every medication available on the market, only to have them stop working after a few short years. Finally, about 10-15 years ago, I started taking Aciphex - no side effects, no resistance... no problems at all. My one and ONLY issue is the cost. I have tried every generic and over-the-counter (supposedly) 'equivalent' with no success."

9 / 10
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41 Report
  • bos...
  • October 14, 2018

For GERD "Taken since 2005, it was the only PPI that worked. In 2018, I started having side effects: tiredness, muscle aches, and complications with cramps in my back and other similar pains related to muscles. Stopped taking it, and the problems disappeared. After 2 months of discomfort and GERD returning, I tried it again, after 3 days, the side effects returned. Time to change, too bad, it worked for 12 years."

5 / 10
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19 Report
  • Ger...
  • Taken for 10 years or more
  • May 30, 2014

For GERD "First had the extreme chest pain (like I imagine a heart attack would be) 10 years ago. Tried many different products with my gastroenterologist's help. Ended up with Aciphex. Of course, the insurance company tried to get me to use other stuff."

10 / 10
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28 Report
  • Cat...
  • June 24, 2013

For GERD "I was first given this medication many years ago. I first got it through the military, then through my private insurance. Then, I put in for a refill and couldn't believe how much I was charged. It became non-formulary with the military pharmacy too, I just couldn't afford it. My doctor has tried different medications, but they don't help like they should. I keep checking to see if a generic becomes available, so maybe it will be formulary somewhere."

10 / 10
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29 Report
  • Anonymous
  • September 4, 2008

For GERD "I lived with severe heartburn for years. It was absolutely crippling at times. I had to essentially watch everything I ate and drank. Aciphex gave me my life back. I recommend looking into it as a possible treatment."

9 / 10
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36 Report
  • Gas...
  • April 5, 2008

For Erosive Esophagitis "I was on other proton pump inhibitors but had a constant headache while using them. Aciphex relieves my symptoms with no perceived side effects. Great drug, and I've been on it for over 10 years. I have no evidence of further esophageal erosion and have been diagnosed by biopsy of having Barrett's esophagus. I can eat anything now."

10 / 10
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35 Report
  • Anonymous
  • August 1, 2011

For GERD "I have taken Aciphex for about a year now, and I cannot live without it. Forgot it on vacation and paid the price. Will not make that mistake again. I, like many others, have tried various prescriptions as well as over-the-counter medicines, but nothing works as well as Aciphex."

10 / 10
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29 Report
  • JD ...
  • May 23, 2008

For GERD "Medicine appears to be working. On my second day, I have no heartburn. I am a little concerned about my headache that I have had all day today. I am hoping that this is but a small price to pay if my esophagus will benefit from this medicine."

8 / 10
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26 Report
  • Man...
  • December 9, 2017

For GERD "I am just on the second day of starting generic Aciphex and cannot believe how great I feel. I have been in pain and diarrhea for a month due to taking multiple meds for a heart issue. Aciphex has been a blessing!"

9 / 10
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13 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.