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Medications for Psoriatic Arthritis

Psoriatic arthritis is an arthritis that is associated with psoriasis of the skin. Common medications used to treat Psoriatic Arthritis include Cosentyx, Enbrel and Humira.

Drugs used to treat Psoriatic Arthritis

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
methotrexate 5.6 46 reviews for methotrexate to treat Psoriatic Arthritis Rx X N X
Generic name:
methotrexate systemic
Brand name:
Trexall
Drug class:
antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Humira 6.8 102 reviews for Humira to treat Psoriatic Arthritis Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Otezla 5.1 133 reviews for Otezla to treat Psoriatic Arthritis Rx C N
Generic name:
apremilast systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cosentyx 5.2 68 reviews for Cosentyx to treat Psoriatic Arthritis Rx B N
Generic name:
secukinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Enbrel 7.6 56 reviews for Enbrel to treat Psoriatic Arthritis Rx B N
Generic name:
etanercept systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Stelara 6.3 25 reviews for Stelara to treat Psoriatic Arthritis Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cimzia 5.4 18 reviews for Cimzia to treat Psoriatic Arthritis Rx B N
Generic name:
certolizumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Taltz 6.2 44 reviews for Taltz to treat Psoriatic Arthritis Rx N
Generic name:
ixekizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tremfya 6.3 24 reviews for Tremfya to treat Psoriatic Arthritis Rx N
Generic name:
guselkumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
adalimumab 6.8 108 reviews for adalimumab to treat Psoriatic Arthritis Rx B N
Generic name:
adalimumab systemic
Brand names:
Humira, Amjevita, Abrilada, Cyltezo, Hadlima, Hulio, Hyrimoz, Yusimry, Idacio, Simlandi, Yuflyma
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Skyrizi 8.6 5 reviews for Skyrizi to treat Psoriatic Arthritis Rx N
Generic name:
risankizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
apremilast 5.0 142 reviews for apremilast to treat Psoriatic Arthritis Rx C N
Generic name:
apremilast systemic
Brand name:
Otezla
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Xeljanz 5.6 14 reviews for Xeljanz to treat Psoriatic Arthritis Rx C N
Generic name:
tofacitinib systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Remicade 8.3 20 reviews for Remicade to treat Psoriatic Arthritis Rx B N
Generic name:
infliximab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
secukinumab 5.3 70 reviews for secukinumab to treat Psoriatic Arthritis Rx B N
Generic name:
secukinumab systemic
Brand name:
Cosentyx
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ustekinumab 6.2 26 reviews for ustekinumab to treat Psoriatic Arthritis Rx B N
Generic name:
ustekinumab systemic
Brand names:
Stelara, Imuldosa, Otulfi, Pyzchiva, Selarsdi, Steqeyma, Wezlana, Yesintek
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
certolizumab 5.4 18 reviews for certolizumab to treat Psoriatic Arthritis Rx B N
Generic name:
certolizumab systemic
Brand name:
Cimzia
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
sulfasalazine Off-label 6.4 39 reviews for sulfasalazine to treat Psoriatic Arthritis Rx B N
Generic name:
sulfasalazine systemic
Drug class:
antirheumatics, 5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
guselkumab 6.4 25 reviews for guselkumab to treat Psoriatic Arthritis Rx N
Generic name:
guselkumab systemic
Brand name:
Tremfya
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ixekizumab 6.3 45 reviews for ixekizumab to treat Psoriatic Arthritis Rx N
Generic name:
ixekizumab systemic
Brand name:
Taltz
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
risankizumab 8.2 6 reviews for risankizumab to treat Psoriatic Arthritis Rx N
Generic name:
risankizumab systemic
Brand name:
Skyrizi
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Bimzelx 10 2 reviews for Bimzelx to treat Psoriatic Arthritis Rx N
Generic name:
bimekizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
prednisone 6.0 6 reviews for prednisone to treat Psoriatic Arthritis Rx C N
Generic name:
prednisone systemic
Brand name:
Rayos
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
leflunomide Off-label 5.8 19 reviews for leflunomide to treat Psoriatic Arthritis Rx X N X
Generic name:
leflunomide systemic
Drug class:
antirheumatics, selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
etanercept 7.7 58 reviews for etanercept to treat Psoriatic Arthritis Rx B N
Generic name:
etanercept systemic
Brand names:
Enbrel, Erelzi, Eticovo
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph

Frequently asked questions

View more FAQ

Learn more about Psoriatic Arthritis

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.