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Medications for Psoriatic Arthritis

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
methotrexate 5.6 46 reviews for methotrexate to treat Psoriatic Arthritis Rx X N X
Generic name:
methotrexate systemic
Brand name:
Trexall
Drug class:
antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Otezla 5.1 133 reviews for Otezla to treat Psoriatic Arthritis Rx C N
Generic name:
apremilast systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Enbrel 7.6 56 reviews for Enbrel to treat Psoriatic Arthritis Rx B N
Generic name:
etanercept systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Humira 6.8 102 reviews for Humira to treat Psoriatic Arthritis Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Stelara 6.3 25 reviews for Stelara to treat Psoriatic Arthritis Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cimzia 5.4 18 reviews for Cimzia to treat Psoriatic Arthritis Rx B N
Generic name:
certolizumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tremfya 6.3 24 reviews for Tremfya to treat Psoriatic Arthritis Rx N
Generic name:
guselkumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Skyrizi 8.6 5 reviews for Skyrizi to treat Psoriatic Arthritis Rx N
Generic name:
risankizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
apremilast 5.0 142 reviews for apremilast to treat Psoriatic Arthritis Rx C N
Generic name:
apremilast systemic
Brand name:
Otezla
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Xeljanz 5.6 14 reviews for Xeljanz to treat Psoriatic Arthritis Rx C N
Generic name:
tofacitinib systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Remicade 8.3 20 reviews for Remicade to treat Psoriatic Arthritis Rx B N
Generic name:
infliximab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ustekinumab 6.2 26 reviews for ustekinumab to treat Psoriatic Arthritis Rx B N
Generic name:
ustekinumab systemic
Brand names:
Stelara, Imuldosa, Otulfi, Pyzchiva, Selarsdi, Wezlana
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
certolizumab 5.4 18 reviews for certolizumab to treat Psoriatic Arthritis Rx B N
Generic name:
certolizumab systemic
Brand name:
Cimzia
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Cosentyx 5.1 67 reviews for Cosentyx to treat Psoriatic Arthritis Rx B N
Generic name:
secukinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
sulfasalazine Off-label 6.4 39 reviews for sulfasalazine to treat Psoriatic Arthritis Rx B N
Generic name:
sulfasalazine systemic
Drug class:
antirheumatics, 5-aminosalicylates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
guselkumab 6.4 25 reviews for guselkumab to treat Psoriatic Arthritis Rx N
Generic name:
guselkumab systemic
Brand name:
Tremfya
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
risankizumab 8.2 6 reviews for risankizumab to treat Psoriatic Arthritis Rx N
Generic name:
risankizumab systemic
Brand name:
Skyrizi
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
bimekizumab 10 1 review for bimekizumab to treat Psoriatic Arthritis Rx N
Generic name:
bimekizumab systemic
Brand name:
Bimzelx
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Bimzelx 10 1 review for Bimzelx to treat Psoriatic Arthritis Rx N
Generic name:
bimekizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
prednisone 6.0 6 reviews for prednisone to treat Psoriatic Arthritis Rx C N
Generic name:
prednisone systemic
Brand name:
Rayos
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
leflunomide Off-label 5.8 19 reviews for leflunomide to treat Psoriatic Arthritis Rx X N X
Generic name:
leflunomide systemic
Drug class:
antirheumatics, selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
etanercept 7.7 58 reviews for etanercept to treat Psoriatic Arthritis Rx B N
Generic name:
etanercept systemic
Brand names:
Enbrel, Erelzi, Eticovo
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
infliximab 7.7 30 reviews for infliximab to treat Psoriatic Arthritis Rx B N
Generic name:
infliximab systemic
Brand names:
Remicade, Inflectra, Avsola, Ixifi, Renflexis
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Taltz 6.2 44 reviews for Taltz to treat Psoriatic Arthritis Rx N
Generic name:
ixekizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
adalimumab 6.8 108 reviews for adalimumab to treat Psoriatic Arthritis Rx B N
Generic name:
adalimumab systemic
Brand names:
Humira, Amjevita, Abrilada, Cyltezo, Hadlima, Hulio, Hyrimoz, Yusimry, Idacio, Simlandi, Yuflyma
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Simponi 5.4 19 reviews for Simponi to treat Psoriatic Arthritis Rx B N
Generic name:
golimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
dexamethasone 10 1 review for dexamethasone to treat Psoriatic Arthritis Rx C N
Generic name:
dexamethasone systemic
Brand names:
Dexamethasone Intensol, De-Sone LA, HiDex, Zcort
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
triamcinolone 10 1 review for triamcinolone to treat Psoriatic Arthritis Rx C N
Generic name:
triamcinolone systemic
Brand names:
Kenalog-40, Clinacort
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Rinvoq 6.7 19 reviews for Rinvoq to treat Psoriatic Arthritis Rx N
Generic name:
upadacitinib systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Orencia 4.7 3 reviews for Orencia to treat Psoriatic Arthritis Rx C N
Generic name:
abatacept systemic
Drug class:
antirheumatics, selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Rayos Rate Add review Rx C N
Generic name:
prednisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
secukinumab 5.2 69 reviews for secukinumab to treat Psoriatic Arthritis Rx B N
Generic name:
secukinumab systemic
Brand name:
Cosentyx
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Trexall Rate Add review Rx X N X
Generic name:
methotrexate systemic
Drug class:
antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
mycophenolate mofetil Off-label Rate Add review Rx D N
Generic name:
mycophenolate mofetil systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Simponi Aria 3.1 8 reviews for Simponi Aria to treat Psoriatic Arthritis Rx B N
Generic name:
golimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dexamethasone Intensol Rate Add review Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
Kenalog-40 Rate Add review Rx C N
Generic name:
triamcinolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
abatacept 4.7 3 reviews for abatacept to treat Psoriatic Arthritis Rx C N
Generic name:
abatacept systemic
Brand name:
Orencia
Drug class:
antirheumatics, selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Acthar Rate Add review Rx C N
Generic name:
corticotropin systemic
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
Amjevita 6.3 3 reviews for Amjevita to treat Psoriatic Arthritis Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
azathioprine Off-label Rate Add review Rx D N
Generic name:
azathioprine systemic
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Clinacort Rate Add review Rx C N
Generic name:
triamcinolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
De-Sone LA Rate Add review Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
golimumab 4.6 28 reviews for golimumab to treat Psoriatic Arthritis Rx B N
Generic name:
golimumab systemic
Brand names:
Simponi, Simponi Aria
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
HiDex Rate Add review Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Inflectra 5.3 4 reviews for Inflectra to treat Psoriatic Arthritis Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ixekizumab 6.3 45 reviews for ixekizumab to treat Psoriatic Arthritis Rx N
Generic name:
ixekizumab systemic
Brand name:
Taltz
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Zcort Rate Add review Rx C N
Generic name:
dexamethasone systemic
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Abrilada Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
acitretin Off-label Rate Add review Rx X N X
Generic name:
acitretin systemic
Drug class:
antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Avsola 4.7 3 reviews for Avsola to treat Psoriatic Arthritis Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
corticotropin Rate Add review Rx C N
Generic name:
corticotropin systemic
Brand names:
Acthar, H.P. Acthar Gel
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
cyclosporine Off-label Rate Add review Rx C N
Generic name:
cyclosporine systemic
Drug class:
calcineurin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Cyltezo Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Erelzi 9.0 1 review for Erelzi to treat Psoriatic Arthritis Rx B N
Generic name:
etanercept systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
Hadlima Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Hulio Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
hydroxyurea Off-label Rate Add review Rx D N
Generic name:
hydroxyurea systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Hyrimoz 5.0 1 review for Hyrimoz to treat Psoriatic Arthritis Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ixifi Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
Renflexis Rate Add review Rx B N
Generic name:
infliximab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tofacitinib 5.2 19 reviews for tofacitinib to treat Psoriatic Arthritis Rx C N
Generic name:
tofacitinib systemic
Brand name:
Xeljanz
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
upadacitinib 6.7 19 reviews for upadacitinib to treat Psoriatic Arthritis Rx N
Generic name:
upadacitinib systemic
Brand name:
Rinvoq
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Yusimry Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
auranofin Off-label Rate Add review Rx C N
Generic name:
auranofin systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Off-label:
Yes
cortisone Rate Add review Rx N N
Generic name:
cortisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Eticovo Rate Add review Rx B N
Generic name:
etanercept systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
H.P. Acthar Gel Rate Add review Rx C N
Generic name:
corticotropin systemic
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Idacio Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Imuldosa Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
Otulfi Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
Pyzchiva Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
Selarsdi Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
Simlandi Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Wezlana Rate Add review Rx B N
Generic name:
ustekinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
Yuflyma Rate Add review Rx B N
Generic name:
adalimumab systemic
Drug class:
TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Frequently asked questions

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Learn more about Psoriatic Arthritis

Symptoms and treatments

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

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