Comparing Trulicity vs Zepbound
| Trulicity (dulaglutide) | Zepbound (tirzepatide) |
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| Trulicity (dulaglutide) | Zepbound (tirzepatide) |
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Prescription only
Trulicity mimics the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It lowers blood glucose levels in people with... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Obstructive Sleep Apnea/Hypopnea Syndrome. Zepbound may also be used for purposes not listed in this medication guide. |
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| More about Trulicity (dulaglutide) | More about Zepbound (tirzepatide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Trulicity has an average rating of 5.3 out of 10 from a total of 971 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 40% reported a negative effect. |
Zepbound has an average rating of 8.9 out of 10 from a total of 299 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 1% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Trulicity side effects |
View all Zepbound side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Trulicity prices |
View all Zepbound prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other tirzepatide brands include: Mounjaro | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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120 hours |
120 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 271 drugs are known to interact with Trulicity:
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A total of 414 drugs are known to interact with Zepbound:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 18, 2014 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.