Comparing Glipizide vs Mounjaro

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Glipizide	Mounjaro (tirzepatide)	Enter another drug to compare

Glipizide

Mounjaro (tirzepatide)

Prescription only

Glipizide may be used in the management of type 2 diabetes to maintain good blood glucose control; however, its effects may wear off with time. Prescribed for Type 2 Diabetes. Glipizide may also be... View more

Prescription only

Prescribed for Weight Loss (Obesity/Overweight), Type 2 Diabetes. Mounjaro may also be used for purposes not listed in this medication guide.

More about Glipizide

More about Mounjaro (tirzepatide)

Ratings & Reviews

Glipizide has an average rating of 6.5 out of 10 from a total of 75 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 28% reported a negative effect.

Mounjaro has an average rating of 8.5 out of 10 from a total of 1285 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 6% reported a negative effect.

View all 75 reviews

View all 1285 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Diarrhea (13.3%)
Weight gain (9.3%)
Nausea (8.0%)
Upset stomach (6.7%)
Dizziness (5.3%)
Headaches (5.3%)
Tremors (5.3%)

View all Glipizide side effects

Nausea (16.5%)
Constipation (11.4%)
Diarrhea (7.9%)
Upset stomach (4.7%)
Loss of appetite (4.5%)
Vomiting (4.4%)
Burping (4.2%)

View all Mounjaro side effects

Drug Class

Sulfonylureas

GLP-1 Agonists (Incretin Mimetics)

Generic Availability

Lower cost generic

No lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	50 each
Strength	10 mg
Per unit^*	$0.39
Cost^*	$19.54

View all Glipizide prices

Quantity	2 mL
Strength	2.5 mg/0.5 mL
Per unit^*	$581.34
Cost^*	$1,162.67

View all Mounjaro prices

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Dosage Forms

Oral tablet
Oral tablet, extended release

Subcutaneous solution

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

4.3 hours

120 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Drug Interactions

A total of 475 drugs are known to interact with Glipizide:

23 major drug interactions (59 brand and generic names)
433 moderate drug interactions (2311 brand and generic names)
19 minor drug interactions (116 brand and generic names)

A total of 414 drugs are known to interact with Mounjaro:

15 major drug interactions (34 brand and generic names)
398 moderate drug interactions (2271 brand and generic names)
1 minor drug interactions (10 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases... View more
Talk to your doctor before using alcohol together with tirzepatide. Alcohol may affect blood... View more

Disease Interactions

First Approval Date

May 08, 1984

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Glipizide uses

Mounjaro uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Glipizide vs Mounjaro

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