Glipizide and Weight Gain: What Users Say

• Ips...
• Taken for 1 to 6 months
• February 20, 2019

Glipizide for Type 2 Diabetes "When I first started taking Glipizide-ER 5mg along with Trulicity once a week, also metformin 1000mg in the a.m. and 1000 mg at night. My blood sugars (BS) were dropping to 100-110. I also have insulin as needed on a sliding scale. I refilled my medicine, but maybe from a different manufacturer, my BS is reading 195-255. I'm constipated, moody as heck, dizzy in the morning. I bounce off the walls like a pinball machine, not to mention that I have gained a lot of weight. I have not changed my diet, not much exercise because I feel like rubbish all the time. Tonight I threw the medicine in the trash. It's bad stuff with too many side effects."

• Dan...
• Taken for 1 to 2 years
• October 9, 2018

For Type 2 Diabetes "Glipizide works very well in lowering my blood sugar, but I gained a lot of weight. I thought it was due to my normal body changes until I started feeling terrible with this new big body. I asked my doctor about it, and he changed my medicine. I had gained 60 pounds in a year! When I stopped glipizide, I lost 20 pounds in the first month, and I'm still losing more. No more glipizide. It is not for me."

• Amd...
• Taken for 1 to 6 months
• June 25, 2019

For Type 2 Diabetes "I was afraid to take glipizide because of weight gain. I’ve had no issues, and with effort, lost weight. It is fast-acting, so I take it before breakfast. No issues of too low glucose levels. Although depending on my numbers in the AM, I may only take a half pill instead of a whole 10 mg."

• Emm...
• September 10, 2017

For Type 2 Diabetes "I have been on Juniva and Metformin for years. It has kept my weight and sugar levels between 91-135. For some reason, my doctor decided to take me off that medication and put me on glipizide. In one month, I had gained 15 pounds, and my blood sugars were in the high 100s to low 200s. After two months, she decided to switch me back on to Juniva. A bit late, I think. My blood sugar is now up into the 300s, and I have packed on another 15 lbs. The glipizide ruined my blood sugars, and an extra bonus, it made me gain weight. DO NOT TAKE GLIPIZIDE FOR A FIRST, SECOND, OR THIRD CHOICE. TRY EVERYTHING ELSE FIRST!!!! There's no out-of-pocket experience, but you pay dearly with your health."

• Rob...
• Taken for 1 to 2 years
• November 16, 2021

For Type 2 Diabetes "Works very well in lowering glucose levels; however, significant side effects. Substantial weight gain regardless of diet/exercise, stomach pain, nausea, bloating, burning/tingling sensation in hands/feet, all of which remit when the drug is stopped. I give a rating of 5 due to fantastic effectiveness at lowering glucose, but the side effects can be substantial."

• Mar...
• Taken for 5 to 10 years
• August 23, 2021

Glipizide for Type 2 Diabetes "When I first was diagnosed with type 2 diabetes, it frightened me enough to watch everything I ate. I dieted hard and lost 35 pounds in about 4 to 5 months. My doctor prescribed Glipizide to go along with the dieting. I brought my A1C from 7.6 to 6.8 in the first 6 months. That was about as low as I could get my A1C, so I guess the Glipizide worked, but only marginally. The only side effect was I actually gained weight back when I stopped being as rigid with my diet."

• Ms ...
• January 25, 2016

For Type 2 Diabetes "Ever since I was taken off Metformin and was prescribed Glipizide ER, my A1C has drastically gone up to 8, and I've gained weight. My abdomen is huge, as if I am 9 months pregnant."