Ubrelvy and Headaches: What Users Say

• jin...
• May 27, 2020

For Migraine "Worst move ever to be on this med! OMG, the headache I got from this medicine was so terrible! Was worse than the migraine! Pain was a 4, took this med and pain turned into a 9.5! Ubrelvy was very expensive as my insurance did not cover it, and the performance was horrible."

• Yik...
• Taken for 1 to 6 months
• May 25, 2020

For Migraine "Terrible drug, the FDA should pull this from the market. Headache was worse with the drug than without. Also had some maniac episodes with this drug. Tried 30 pills total 50 mg, same results each day I tried. Did not work for me at all. :("

• Sha...
• Taken for less than 1 month
• March 15, 2021

"I had migraines for over 20 years, it went dormant for 20 years. It wasn’t until the last 2 years that my head pain has been 10 times worse, always on the left side, and constant. I’ve tried over 10 medications, 2 nerve blocks, 2 Botox treatments, and Emgality for 3 months. I’ve had no relief, I finally got approved to try Ubrelvy 100 mg. I’ve experienced the worst side effects, I was awakened at 2 a.m. in the morning with the headache worse. It was sharp pain, throbbing, pin needles on both sides of my head, and uncontrollable leg twitching."

• Sha...
• Taken for less than 1 month
• March 15, 2021

"I had migraines for over 20 years, it went dormant for 20 years. It wasn’t until the last 2 years that my head pain has been 10 times worse, always on the left side, and constant. I’ve tried over 10 medications, 2 nerve blocks, 2 Botox treatments, and Emgality for 3 months. I’ve had no relief, I finally got approved to try Ubrelvy 100 mg. I’ve experienced the worst side effects, I was awakened at 2 a.m. in the morning with the headache worse. It was sharp pain, throbbing, pin needles on both sides of my head, and uncontrollable leg twitching."

• SSu...
• Taken for less than 1 month
• January 16, 2023

For Migraine "I can’t take triptans, so my doctor is having me try Ubrelvy. I cut Ubrelvy in half to 50 mg on the two occasions I tried it. Then I proceeded to feel doped up and trying not to die for the rest of the evening and night. Horrible anxiety, persistent heart palpitations, weird vision changes. I’ve taken typical and atypical antipsychotics, and this Ubrelvy is worse. It’s like being behind a veil. Like you just feel off. IDK how to describe it. Like some weird hybrid of being high on cannabis/alcohol and mixing that with Benadryl, but not groggy, but also incapable of functioning. Just wrong. Then the next day I’m hungover from it. It also causes headaches in me, and I rarely, if ever, have headaches."

• jul...
• Taken for less than 1 month
• August 16, 2024

For Migraine "The doctor gave me a sample on day 2 of a migraine. I took the sample on day 3 when I returned home from doing errands as I did not know how it would affect me. Within an hour, I felt extremely lethargic, and my head felt heavy, but the pain was dulled. I went to lie down, but I could not fall asleep. After another hour, I got up, and my head felt better than it had in days. I continued on with my evening, but by bedtime, I was wired! I could not sleep even with sleeping pills! The next night's sleep was troubled, but my head remained pain-free. I will have to take another dose to see how it will affect me, but I would rather be tired than have a migraine."

• Ell...
• Taken for less than 1 month
• January 19, 2021

For Migraine "The first time I took 50 mg Ubrelvy, I noticed the pain went away fast without side effects. However, the pressure headache reoccurred after 3 days. Although the headache was tolerable, I was worried that if I don’t take care of it right away, it will be unmanageable again. I took Ubrelvy again, but the pain didn’t go away. Had to take ibuprofen after that, and this time it went away. After 2 days, the headache is back again."

• Kei...
• Taken for 1 to 6 months
• February 1, 2023

For Migraine "32-year-old male with daily migraines... Ubrelvy and most G-Pant drugs will stop the migraine, HOWEVER, they make your blood sugar go up and down. I found that my son with autism benefits MOST from taking 50 mg Ubrelvy in the morning with food, and 50 mg Ubrelvy with dinner at night to stop migraines. Be prepared to eat a small protein snack every 2 hours to stop the anxiety that naturally comes when your blood sugar is spiking and dropping. A half of a protein bar, 1-2 peanut butter crackers, or some nuts with a small glass of fruit juice every 2 hours for about 6 hours after a dose has my son feeling GREAT. YOU CAN have rebound headaches with any headache medicine if it is taken daily, so I try to also give him Nurtec some days and sumatriptan some days. BUT Ubrelvy has worked the BEST... IF you can control the blood sugar problems with this drug, you'll have LESS anxiety and LESS headaches. Blood sugar problems can also cause migraines, so be prepared to take protein snacks if you take these G-Pant medicines."

• KD6...
• Taken for 1 to 6 months
• November 13, 2022

For Migraine "I tried two samples of 50 mg and 100 mg and also had 4 samples of Nurtec too. The 50 mg Ubrelvy barely touched the pain, it dulled it enough for me to go to sleep, to sleep the pain off. The 100 mg did work slightly better, BUT!!!!! I woke up 2 hours later WIDE AWAKE! I opted to get a prescription for the 100 mg as the 50 mg wasn't enough, and Nurtec was horrible, it gave me a way worse headache!!! Well, I took a 100 mg Ubrelvy Tuesday evening, and I haven't slept since!!! It's currently 3 am Sunday! I've been up till 4 am every night. Saturday I did sleep in and take a nap, but here I am wide awake almost 3 am. Try it, but don't count on it being side effect-free. I'm considering just getting some type of sleeping pill for when I do get a migraine, I just need to sleep it off. Literally, the only thing that works. I will add though I have been getting Botox and trigger point and occipital nerve block injections, and that has dulled my daily headaches. My daily pain went from 7/8 down to 3/4. But the migraines are still 10!"

• Jes...
• October 13, 2021

For Migraine "I wanted to love this. I wanted to put the triptans away and lean on this. What a huge mistake. Ubrelvy will bring my level 5 migraine to a level 12. It's awful! I've had this script filled twice (desperate measures) to make sure it was the med actually making my head worse. I'll never take this again! Back to triptans I go until something better comes along!"

• Kri...
• Taken for 6 months to 1 year
• January 16, 2025

For Migraine "I have been happy with the results. I don’t feel sleepy very often after taking Ubrelvy, and most of the time my headache is gone after a couple of hours. It doesn’t work as quickly as some drugs, but I don’t feel like I get rebound headaches and have fewer side effects than other drugs I’ve used for headaches."

• Alm...
• Taken for 1 to 2 years
• March 18, 2023

For Migraine "After happily using Ubrelvy 50 mg once a week, I am now experiencing 2-3 days of rebound headaches after the one dose."