Ubrelvy Dosage

Generic name: UBROGEPANT 50mg
Dosage form: tablet
Drug class: CGRP inhibitors

Medically reviewed by Drugs.com. Last updated on Mar 21, 2025.

2.1 Recommended Dosage

The recommended dose of UBRELVY is 50 mg or 100 mg taken orally with or without food.

If needed, a second dose may be taken at least 2 hours after the initial dose. The maximum dose in a 24-hour period is 200 mg. The safety of treating more than 8 migraines in a 30-day period has not been established.

2.2 Dosage Modifications

Dosing modifications for concomitant use of specific drugs and for patients with hepatic or renal impairment are provided in Table 1.

Table 1: Dose Modifications for Drug Interactions and for Specific Populations
Dosage Modifications	Initial Dose	Second Dosea (if needed)
Concomitant Drug
Moderate CYP3A4 Inhibitors (7.1)	50 mg	Avoid within 24 hours
Weak CYP3A4 Inhibitors (7.1)	50 mg	50 mg
Strong CYP3A4 Inducers (7.2)	Avoid concomitant use
Weak & Moderate CYP3A4 Inducers (7.2)	100 mg	100 mg
BCRP and/or P-gp only Inhibitors (7.3)	50 mg	50 mg
Specific Populations
Severe Hepatic Impairment (Child-Pugh Class C) (8.6)	50 mg	50 mg
Severe Renal Impairment (CLcr 15-29 mL/min) (8.7)	50 mg	50 mg
End-Stage Renal Disease (CLcr <15 mL/min) (8.7)	Avoid use