Methotrexate for Psoriasis User Reviews (Page 2)

• ARn
• Taken for 1 to 6 months
• July 5, 2013

"I have been suffering with psoriasis for 4 years now and with each year it keeps on getting worse. The guttate psoriasis covers 80% of my body. I have tried ointments, light therapy and now methotrexate. All treatments work for a while but oddly enough the psoriasis comes back with vengeance. New spots appear. My dermatologist explained to me that it takes 3 months for methotrexate to work. It slightly cleared up my Psoriasis the first month but on the third month my psoriasis came back even worse. I'm glad to read that this medicine has done wonders for many but it just didn't work for me."

• Equis
• February 11, 2015

"I have autoimmune disease and at the age of 65 developed sudden onset psoriasis on my body (arms, neck, chest, legs, ankles, scalp). Within one month of methotrexate treatment (.05 cc once a week) the psoriasis was noticeably disappearing. I have been taking a weekly dose for six months now and have had excellent results. I am also taking Folic Acid and have blood testing done about every 45 days. At this point I have had no adverse side affects and am grateful that I have relief from the psoriasis. In addition, the drug has given me moderate relief from hand and foot joint pain."

• Josie
• Taken for 2 to 5 years
• May 30, 2017

"I've suffered with scalp psoriasis from being 8 years old but always managed with coal tar shampoos. When I was 29 I noticed plaque psoriasis forming on the trunk of my body, arms and legs, chest and face! They grew larger, became intolerable and so itchy. After many visits to the GP I was eventually referred to a dermatologist. By this point I was off work severely ill, my skin was so bad I couldn't walk, I would lie in the bath to help shed the layers of skin. Upon my visit to dermatologist he took one look and said I was critical. I was 99% covered and had erythrodermic psoriasis! I spent 11 days in hospital bandaged in ointments. I've been on MTX for 4 years now and can say they have helped me a lot (99%). Blood monitors done 3 monthly. "

• Snapc...
• November 21, 2017

"Sooo I'm 26 been suffering 5 years. It started in my scalp and then spread to my ears eye lids elbows knees and little patches on my torso. Last year to my horror it decided to make an appearance on my penis and stayed and got worse for the whole year. At this point I was as low as a man could be. Constantly on my mind constantly severely depressed with it and was annoyed with things that don't work. I was in lots of pain and self confidence non existent just wishing for a life with nice skin. Three weeks ago I was put on methotrexate. One week later my penis was totally and i mean totally clear and has stayed clear "

• Anonymous
• November 3, 2011

"I have been on 15mg methotrexate for one year for psoriasis and psoriatic arthritis. My psoriasis was mild to moderate and is a little better but I was in a lot of pain from the arthritis and this medicine has helped me so much. I would say my pain went from a 9 to a 3 on a scale of 1-10. Only side effect is stomach upset and I am considering switching to injections."

• starg...
• July 29, 2013

"During the Christchurch earthquakes my mother (who's had psoriasis all her life) and myself broke out big time. We found a specialist and got put on this. It cleared up in a matter on 2 weeks for mum, for me it was 3-4 weeks. We both have had no side effects. However, now 1 yr later after moving to Auckland I can't find a doctor who will supply it to me. One week from being off it and has all come back. Just want to be a normal 20 yr old. If you got a doctor who prescribes this, don't let them go."

• Gmh
• Taken for 2 to 5 years
• June 1, 2016

"I was on Methotrexate for 3-4 years after trying every option I started 17.5mg when I was 19. It cleared my psoriasis perfectly! I struggled with side effects. Weakness and exhaustion, loss of appetite which lead to severe weight loss, and nausea. I changed to the injections at 20mg, and found a huge differences in side effects. Still not a lot of energy but not going through my stomach was better for the nausea and appetite so I could get healthy. I stayed on methrexate for as long as I could before I felt it was draining me. Now I am off it for 1 year and hav bad psoriasis again i wondering if it's best to go back on. both effect you in different was, emotionally and phsically."

• brook...
• Taken for 1 to 6 months
• April 5, 2015

"Started with pill form of methotrexate at 15 mg dosage per week. Moved to injection form and increased dosage to 25mg per week. Seen lots of improvement on my psoriasis. Tired the day and day after injection but not concerned. Stomach a bit irritated but a little drawback for the good benefits."

• Anonymous
• August 23, 2011

"I have had psoriasis for over 40 years, and although it's just on my elbows and legs, I have tried all the usual remedies (topicals, light therapy, etc.). I tried methotrexate this spring and in a matter of weeks, my psoriasis began to clear up. My doctor has me go for blood-work every month or so to make sure the methotrexate isn't affecting my liver. We have decided to back off of the methotrexate during the winter in order to give my body a break. But, I'll be anxious to begin it again come spring!"

• Craig
• Taken for 10 years or more
• February 2, 2024

"Have been taking Methotrexate for plaque psoriasis (up to 75% skin coverage) for 46 years (I am 75 now). Dosage has been 25mg once weekly. Had two liver biopsies earlier in my treatment, both good. For the last 30 or so years, I have just relied on liver function blood tests - all good so far. I was lucky, I guess, that I never experienced gut issues or hair loss. I am mostly 100% clear. Infrequently, I find a small patch on the scalp area, but MTX has been a godsend for quality of life improvement."

• Gdad...
• Taken for 10 years or more
• July 9, 2016

"20 years ago I was put on methotrexate after being diagnosed with psioritic arthritis. At the time I was riddled with pain & had great difficulty walking. Thanks to methotrexate my pains are almost gone & I was able to work to 65 & love walking since I retired. Only prob been April this year when I had a severe reaction to my " new " methatrexate tablets ( my chemist changed supplier) . The pharmacy at the hospital stock my original tablets ( by Orion Pharma & marked 2.5mm ) so all I did was change to a pharmacy that would supply the correct tablets. Wonder how many have had the same prob or even had to come off altogether ???"

• Anonymous
• Taken for 1 to 6 months
• October 26, 2013

"I have had psoriasis since I can remember, last year after a foot injury I developed psoriatic arthritis. Since it has spread to both feet, both knees, one hand and lower back. Leaving me hardly being able to walk at 30. I started methotrexate 4 weeks ago and it is helping a lot. Only side effects for me are fatigue. I do 1 ml injections once a week. If you have PsA, get on methotrexate. If you can handle the needles injections are the way to go."

• dylan...
• Taken for 1 to 6 months
• July 2, 2017

"I've had psoriasis since I was 7 years old, I am now 17 and was put on methotrexate in January. My psoriasis was completely covering my back and torso to the point where I couldn't bend over as it would cause the skin to crack, leaving me often times covered in blood and under severe pain. Now 6 months on my psoriasis is 99% gone, with a stubborn few plaques remaining on my legs stomach and back, but extremely small (size of a pea!). However the areas where the psoriasis once was is left with a darker pigment to the rest of my skin, I am hoping with continued use it shall fade over time. I've experienced no side effects of this medicine (my dermatologist said I was a good candidate as I'm younger and have a stronger immune system."

• Mr Mac
• Taken for less than 1 month
• August 9, 2016

"I have been prescribed methotrexate for psoriatic arthritis at 5 x 2.5 dosage once a week, followed by 3 days of folic acid. The day after I took it for the first time I was disabled with voting, nausea and flu like symptoms. I felt awful but persevered. Week 2 and the same happened but this time with a very runny nose - like a waterfall. I was vomiting so badly that yellow bile was coming out - it felt like the lining of my stomach had been shredded. I stopped taking them. I felt I was dying - bloody awful drug"

• Razwan
• Taken for less than 1 month
• October 14, 2016

"I had a good experiance with Methotrexate. I've been fighting with psorises for last 8 years. I'm 35. I tried so many things. One of my doctor gave me methotrexate just to try on me 4 years back. 2 tables a week. For 3 weeks For example ( if I took one table in morning and one in evening in monday. Then the same dose on next Monday. And the last one next Monday.) So after this dose my psorises disappears for 6 to 7 months. I repeat this dose onces a year. But the best effected treatment for me was herbal treatment from China. I stayed there for 3 weeks . They gave me herbals to boil and drink the water with proper diet. I did this for 4 months and my psorises was gone for 12 months. I was not able to continue that diet n treatment."

• Anonymous
• May 21, 2008

"Worked wonders for me. I suffered from Psoriasis covering the insides of my hands. Was very painful. Would crack and bleed. Tried many creams and other meds. Once I started this medication it cleared up quickly. Am now able to use my hands again."

• Bicol...
• July 24, 2011

"I have been in methotrexate for 6 weeks now. So far, itchiness has been reduced significantly; lesions in my lower leg have dried up (light brown now); other lesions appear to be clearing up though slowly. Side effects to me are nausea, feeling giddy and occasional headache though not severe. May I ask those who are in the same medication: how long did it take for all lesions to be cleared? about 70% of my body has psoriasis. Thank you. ."

• laure...
• July 22, 2013

"I am just diagnosed with psoriasis on May 2013 and I am on my 3rd week of methotrexate and so far it cleared the psoriasis on my neck and under my breast. It stops the wetness and flakes and the ones in my arm and tummy are lesser in flakes. I just hope that my dermatologist will allow me to continue the medicine, but it depends on the lab results on my liver."

• sanju
• April 1, 2009

"I have been a victim of psoriasis for the last seven years. I came to know about this drug from a skin specialist in the year 2004. Prior to this I was covered up to 75% but when I took this it vanished after taking a mere 30 mg. It recurred in year 2005. Since then I am taking it frequently, as I did not find any other alternative to fight this skin disorder. As far as my personal experience is concerned, I didn't have any side effect. "

• oneta
• March 30, 2013

"My mother broke out seemed like overnight with red bumps that quickly turned into dry patches. The dermatologist knew right away what it was. We have been on the Methotrexate for 6 weeks and the flaking is totally gone and is healing. The dose was 2 Friday morning, 2 Friday evening and 2 Saturday morning. Only side effect was appetite and very tired for 2 days."

• wildk...
• February 4, 2010

"I have had psoriasis for over 10 years and for the first 5 years it was very mild, but in 2005 it quickly got worse and covered 70% of my body in various spots such as my entire scalp, under my breasts, on my elbows and knees, in my pelvic area and a few other random spots. I was prescribed (5) 25mg pills (1x wk) of methotrexate after trying every cream imaginable and the photo light therapy. The medication made me extremely sick to my stomach. After seeing some improvement my dermatologist recommended I try the tanning bed along with the medication. Within 6 months my psoriasis was completely gone. 4 years after being off the medicines it has come back. It is worse than before and I am taking the medicines and am getting sick a lot. Hope it works again."

• Sherry
• January 21, 2009

"I've been on this medicine for about 3 weeks. I have psoriasis on my hands and feet. I can walk again and do NORMAL things without my hands cracking and bleeding. So far I haven't had any side effects that are related to this medication."

• Flaky
• Taken for less than 1 month
• January 18, 2017

"I have had Psoriasis for some number of years, since my 50s started and prior to that nothing more than a dry elbow. I tried all the usual stuff and I mean all of the junk I could waste money on.I broke down an went to derm doc and went with steriod cream and blulight with very little change. So I quit derm doc for a few years and then become desperate as my Psoriasis went totally off the charts, and I started the methotrexate med or as i call it chemo pills. So far the itching seems to have let up a fair amount an I'm only on week one , The side effects are not at all like I had feared .I'm terrified of new medicines as so many meds seem to be on the lawsuit. I have noticed a loss of energy but nothing drastic,and aside from that no problems."

• Anonymous
• June 20, 2008

"I have had Psoriasis for 12 years. While it has not helped the stubborn patches on my scalp and groin, it has been very helpful for my joints. However, I am taking 15mg once a week and after 5 days my hands and feet ache again. I feel very old sometimes. As we know, it's trial and error. This is worth the risks so that I can shop, play Frisbee, and simply act my age."

• wrighth
• August 7, 2015

"I started methotrexate in September 2014 as my body was 75% covered with psoriasis and I had tried every topical/light treatment going. The drug worked wonders and I couldn't believe how my skin was clearing up, by jan/feb I'm actually wearing dresses without tights and short sleeves (especially at work which I'd never done before) the only downside was that the day after I took methotrexate I felt so tired I've ended up having days off work because of it, I decided to come off it in about may 2015 and am now waiting to try a new drug Adalumimab (spelling!?) and my skin has come back worse from methotrexate I'm in so much pain and I'm covered in guttate :(."