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Methotrexate for Psoriasis User Reviews (Page 4)

Brand names: Methotrexate LPF Sodium, Trexall, Otrexup, Rasuvo, Xatmep Jylamvo

Methotrexate has an average rating of 8.1 out of 10 from a total of 86 reviews for the treatment of Psoriasis. 76% of reviewers reported a positive experience, while 9% reported a negative experience.

Reviews for Methotrexate

  • Deborah
  • Taken for 2 to 5 years
  • June 29, 2023

"When taken regularly, it cleared 99% of palmar plantar psoriasis. It began with 15mg once a week. That dose cleared my hands after 6-10 weeks, but it didn't fully clear my feet. The dose was increased to 17.5mg, and my feet gradually cleared. I attempted a methotrexate "holiday" of 6 weeks, and my foot symptoms returned and were stubborn this time. The 17.5mg dose didn't get on top of it until the dose was increased to 20mg for a couple of months. Then, I returned to 17.5mg. Some weight loss has been achieved by going to the gym (the specialist advised me to lose weight, as I was over 80kg). I am currently on 17.5mg and about to reduce the dose back to 15mg, to test if this is the lowest effective dose. SIDE EFFECTS: Very few. Feeling "wiped out" (fatigue) for a day or two after the dose. Occasional loose bowel movements. I notice that I'm prone to bruising. Hair thinning could be due to age (65). I lost much more hair on the Accutane drug."

9 / 10
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2 Report
  • VinVin
  • November 1, 2020

"Hi I suffered from Psoriasis for 7/8 months with acutely cracked feet and hands. It was painful & embarrassing. I tried all therapies - homeopathy naturopathy. Ayurvedic treatments, nothing worked. Then I resorted to Allopathy- Doctor started with steroidal creams on cracks and they healed a bit. But later after 2 months he put me on Folitrax 10 mg and I responded well with no discomfort. Then he increased to 15 mg till today (10 months of treatment )with DOM- DT , folitrax 15 and a folic acid tab 24 hr later/ week. --- I get at times discomfort in head and stomach but you should not lie down after these meds-- work and be more active ! I started getting hair fall so Doc gave me cal pentothenate. - I have totally stopped - milk products, nightshades and all gluten. I have lactose free milk, jwar bajra ragi flour and white of egg, pulses ( no kidney beans or chanas) veggies with least condiments. I am now thankful for my soft n supple hands and feet."

10 / 10
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4 Report
  • scain
  • Taken for 1 to 6 months
  • December 14, 2021

"I have had psoriasis since 2008. I am 67 years old and have had psoriasis on the bottom of my feet since 2008. Last summer it showed up on the palms of my hands, between my fingers, and the tips of my fingers. Having been advised by my dermatologist to take methotrexate years ago I finally gave in and started taking 15mg once per week and 1 mg of folic acid 6 days per week. I started this regimen in October. My feet and hands are finally starting to clear. The first day after the meds I feel wiped out. I wish I had started taking this medication a long time ago. This medication has given me my life back!"

10 / 10
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3 Report

Frequently asked questions

  • Mary
  • Taken for 2 to 5 years
  • October 10, 2021

"Dx with moderate severe psoriasis at age 14 and am now 66. Tx with topicals & UVB for decades. Began 15 mg methotrexate & 1gm folic acid 2 yrs ago & skin is mostly clear. Some fatigue but routine blood work is WNL. Thankful for this drug and encourage psoriasis sufferers to consider it."

9 / 10
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1 Report
  • Anonymous
  • April 22, 2008

"Psoriasis covered over 80% of my body!!! After 2 weeks on this medicine it was CLEAR!"

10 / 10
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76 Report

Are you taking this medicine?

  • karen...
  • July 15, 2015

"i was getting suicidal from severe scalp psoriasis methotrexate cleared it up,my bald spts went away but for a week ive noticed hair loss and patches coming back,i'm so upset"

10 / 10
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29 Report
  • kog
  • December 28, 2010

"I started on methotrexate tablets at first but they made me feel very sick so was put on injection made me feel a lot better. "

8 / 10
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37 Report

More FAQ

  • pokka...
  • October 17, 2010

"Methotraxate is very useful for psoriasis. I have been taking 20 mg every week."

9 / 10
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36 Report
  • Anonymous
  • January 14, 2009

"Pill form is very hard on stomach, lots of sickness. But I have found the injectible form to be fantastic."

9 / 10
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37 Report
  • Anonymous
  • February 10, 2009

"My psoriasis has improved by about 80-90% in one month. The joint pain continues after two months."

8 / 10
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30 Report
  • FALLEN
  • Taken for less than 1 month
  • August 13, 2020

"After 2 weeks of METHOTROXATE usage, I don't see any improvements. My skin and nails is getting worse, like every day before using any drugs at all. Basically "Zero" effect from this METHAOROXATE."

1 / 10
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9 Report
  • Saurabh...
  • November 2, 2020

"I just take this methotrexate for 2 days of 5mg and I felt very tired , dizziness and loss appetite too. This is really not a good medicine. Don't take this please"

3 / 10
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6 Report
  • Alper...
  • Taken for 6 months to 1 year
  • April 18, 2017

"-I vomiting after alcoholic drinks. -Overall fatigue. -My joints are more sensitive"

7 / 10
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7 Report
  • BHARAT
  • Taken for 1 to 2 years
  • June 28, 2023

"The doctor gave me a cure for rheumatoid arthritis in my finger. I also had psoriasis, so it cured both."

10 / 10
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1 Report
  • Grayl...
  • October 11, 2022

"Has worked very well for me even on a low dose. I also started taking Repatha for my cholesterol and that also reduced my problem with my place psoriasis!!!!!!!"

10 / 10
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1 Report
  • FAYE
  • Taken for 2 to 5 years
  • June 7, 2023

"In the beginning, I used to get very fatigued and had diarrhea. Now 5 years later, I am ok. I am still on the meds and they are really helping me."

9 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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