Methotrexate for Psoriasis User Reviews (Page 3)

• Johnny...
• Taken for less than 1 month
• May 12, 2017

"I am 27 and started having psoriasis when I was 20. I am covered 80%. My rheumothogist has started me on methotrexate shot once a week as well as folic acid everyday but the day of the shot. I am currently on day 5, my skin has stopped forming layers about 90% but still red and small patches here and there. From the time I got the shot, I have only felt low energy and low appetite. No serious side effects. I must add before going on methotrexate, you should start eating healthier and detox the body the best you can for a month prior to going on methotrexate. If you don't you are doing more harm than good because your immune system is going to sleep mode and if you got a load of junk and bad bacteria left they will just take over."

• Austi...
• February 12, 2016

"On methotrexate for 20 years, no issues w/liver function. Otezla worked much better, but ins. refused to cover it, back on metho. Psoriasis since age 7, psoriatic arthritis since 40's. Now 54. Increased metho from 10mg/wk to 15/wk, pain and scaling more severe. New patches around my eyes, lids are swollen, painful and itchy. Eyes constantly dry, red, painful, itchy - might have psoriasis and/or psoriatic arthritis in them, going back to rheumatologist and an opthalmologist for help. OTC allergy eye drops, soothing drops and nightly administration of Vaseline in/around eyes not alleviating condition. Very sore all over, sunny weather alleviates the patches and joint/tendon pain. Can't wait to sunbathe! No biologics, cancer scare."

• kuli
• Taken for 1 to 6 months
• December 30, 2015

"I've been taking this medicine for 9 weeks now. I'm taking 7.5mg once a week but have seen NO difference whatsoever! All I seem to be getting is little boils everywhere, sickness, nausea and weight gain! :("

• Anonymous
• June 15, 2008

"I tried a number of different treatments, but only methotrexate helps. I had it in my scalp, back, genital area, mostly body parts that were not exposed to sun and air, which I find interesting. My doctor said sun exposure would help and it works for me. Still have a little on my scalp, but usually one application of Olux will clear it up."

• Adrian
• Taken for 1 to 6 months
• December 29, 2023

"After 3 weeks using this medicine, I’ve seen drastic changes in my skin. I could honestly say my skin is finally healing after being covered around 75% of my skin. I’ve tried Enbrel and Otezla, and I did not see results like methotrexate. So far, I have not had any symptoms to this medicine. Like many people, I was skeptical and scared to try this medicine based on the side effects, but I don’t regret giving this a try. The healing definitely outweighs the side effects, in my opinion."

• Redfear
• Taken for 1 to 2 years
• November 29, 2017

"Have done 3 'rounds' of this, 4 weeks each and have never been so exhausted, sick to my stomach and out of it. It helped clear up the Guttate psoriasis and inverse psoriasis but didn't do much for the psoriatic arthritis."

• Anonymous
• July 29, 2009

"I have suffered several types of chronic psoriasis, including the life threatening form for 50 years. After developing severe disability from Psoriatic Arthritis I gave in to taking this drug, my skin is 90% improved, inflammation much better, but still have high inflammatory markers in blood tests. Now on steroids. Nausea still persists so I take folic acid."

• azure
• June 6, 2013

"Just started a week ago. Was nervous regarding side effects but bit the nerves. Notice there is no flaking after one week. Although still itchy hopefully that goes away. Just felt like I was exhausted faster but want to keep giving it a try. Tried everything else."

• Anonymous
• Taken for 1 to 6 months
• May 17, 2017

"I have been extremely tired, nausea's, a general feeling of lack of interest in things I enjoy, moody and overall not feeling good. The psoriasis has become less thick, but after six weeks its still there. I have an appointment Thursday and going to discuss alternatives."

• Better...
• January 12, 2016

"I've had psoriasis for the past 10 years and was exhausted from trying creams and such. I searched for a treatment that would do more - and have been on methotrexate for about 7 weeks now. I haven't noticed any change in my skin - atleast not for the better. I've been really itchy, and I really feel like my scalp has gotten worse. I have flakes constantly and my head is covered in acne and red bumps now. My face is getting a bit of acne too. And, despite the fact that I eat very healthy and work out, I have put on about 2 pounds per week. :( So sad"

• Court...
• May 27, 2017

"I'm 18 and have had psoriasis now for almost 2 years. I started taking this for my psoriasis about a month ago and have already seen substantial differences! No itchiness, limited redness and extreme scaling. Although the medication does take a bit longer to start working I'm absolutely sure that it will continue to help relieve the psoriasis on my legs, arms and stomach!!"

• enigma
• March 3, 2009

"I have been on methotrexate now for 6 months. Its great as I was 85% covered with psoriasis and it improved almost instantly by 90%. Although there is one drawback, I get recurrent bouts of bacterial vaginosis, which is most uncomfortable and have to then take high dose of antibiotics (which make me feel very sick for a few days). "

• Mary...
• Taken for less than 1 month
• June 3, 2019

"I was just diagnosed which psoriasis about 2 months ago. I tried all kinds of creams and ointments, put my feet in Saran Wrap when I went to sleep. Nothing seems to work. It's on the bottom of my feet and my hands. My hands are scaly dry and cracked and my hands hurt all the time. My feet are dried and cracked with scales all over them mostly it hurts my heels when I walk. The doctor put me on this medication and with folic acid to. I've been on it a week now haven't seen any results yet still in a lot of pain hope it works."

• Snowf...
• August 1, 2015

"I have suffered with psoriasis for 30 years and have tried every possible lotion potion shampoo etc that my dermatologist has recommended - I started taking 10mg methotrexate once per week only 1 month ago - I have not noticed any reduction In scale patches and I am still quite itchy - is this Normal??"

• Jkano
• Taken for 6 months to 1 year
• May 28, 2019

"I have suffered from psoriasis for about 12 years but had a serious bout of arthritis 2 years before that so psoriatic arthritis. Was able to stay away from chemicals for years managed using supplements but it carried on spreading. Finally referred to dermatologist and was on cyclosporine for over a year, had to come off due to effect on gums and high BP which was controlled with tablets. On methotrexate since October, no nausea etc but had lots of urine issues in the beginning which I later realised was actually due to too much folic acid, lowered the folic acid dose and it was sorted. Recently realized that my joints and muscles have been hurting since I started methotrexate. Painful feet legs etc effecting my everyday exercise routines so will be speaking to dermatologist about it in about two weeks."

• Trista
• Taken for 2 to 5 years
• March 21, 2019

"I've been on Methotrexate for 3 1/2 years for a mystery rash, 4 areas on my thighs, 4 on my back and one in my heel. Dosage scaled up to 20mg 1x per week and I recently reduced to 7.5mg/week. Folic acid 1mg/day. It did eliminate my rash, where no other drug, aside from prednisone, would. I developed tinnitus (ears ringing) 3 weeks ago and discontinued methotrexate. Ears are ringing constantly. I believe it is from methotrexate, I have otherwise excellent health and hearing. Wondering if anyone else has experienced ears ringing from methotrexate. I have not had any other side effects others have reported - hair thinning, liver impairment, etc."

• MickS...
• May 31, 2015

"68 year old male who has had Psoriasis for 46 years with coverage up to 90% of my body. No one would initially R(x) me methotrexate so I flew to Trinidad from Canada to see a doc there that would prescribe it. After the initial treatment I was totally free for three years then it came back. I was on every research pgm my cream passes could put me on PUVA, Soralyn, vit A, coal tar, retanoic acid, that stuff that turns everything purple (can't recall name). Finally I had to see a head shrinker as I was fairly emotionally messed up. He R(x)ed me methotrexate 2.5x3 every 12 hours for 36 hours, said not to drink and that I should get liver bios. I've had 10 invasive liver bios in 46 years 10 years ago I said no thanks no more. I'm clear."

• Sebas...
• March 30, 2017

"I have had psoriasis for 12 years. It affected my daily life. I have tried so many creams, ointments. Nothing worked. So last November, doctor prescribed me Otezla, it hurt my back badly. I have to stop this. So methotrexate was given to me 5x2.5mg per week in January, 1mg folic acid per day except the day taking methotrexate. Once a month blood work was giving. I was on 7x2.5 mg last month, Now I am on 9x2.5mg, I can feel it is almost clear, and I do feel joint pain and weak immune system. I have such bad flu right now and could go to office Tomorrow."

• Wandrer
• June 29, 2011

"I have had severe psoriasis on my hands, elbows, and heels for the past 2 years. Came out of nowhere. Tried everything out there (steroids, antihistamines, light treatments (two periods of it) So now I'm on this medicine. It's only for the second week, but the only difference I see is getting a urinary tract infection. Hopefully I will see improvement soon."

• Picnic
• April 30, 2016

"After 20 years of psoriasis and having had light treatment and creams I was prescribed cyclosporin which was fantastic. Almost clear within 2 weeks but over a long period of time it affected my kidneys. Been on methotrexate for 1 week 12.5mg per week and no real change. Not as quick as cyclosporin but I am hopeful it will clear soon"

• kimbak
• March 26, 2010

"I have had psoriatic arthritis since age 10. The deformities in my hands are very, very severe. I have taken methotrexate for about 6 weeks, and don't notice a difference, except have been feeling sick to my stomach, tired, and bowel - movements are painful and a little blood is visible. Kinda scary--I see my rhematologist in a few weeks. Psoriasis patches seem burning or itchier."

• chinc...
• Taken for less than 1 month
• July 28, 2019

"I have been dealing with psoriasis since I was about 8-9 years old, maybe even before - I'm now 23. I've tried all kinds of creams, ointments, and shampoo and nothing seems to work to where its tolerable. It started with my scalp and in between my toes, now its progressed to my face (eyebrows,nose), behind/in ears, and even worse on my feet now. I was put on methotrexate 3 weeks ago and it seems like it's gotten a lot worse before I was even put on it. Summer time is the worst time for me cause the minute my scalp gets warm I itch like crazy til I bleed. Its just terrible."

• nick
• March 14, 2017

"I am 25 years and I have psoriasis from the age of 20. The treatment helped to completely leave the psoroasis was methotrexate and solarium. Now I have no psoriasis and as a treatment( to not appear again) is to do solarium for 5 months of the year"

• Bevp
• September 1, 2020

"Was on methotrexate for over a year for Psoriasis. First tablet form then changed to injections. Was stopped due to pains in side 2 weeks in on injections. Have just started cyclosporin 100mg twice a day to be increased to 150mg after 4 weeks and the difference in my hands psoriasis is amazing after just one week on methotrexate"

• chungus
• Taken for 1 to 2 years
• November 23, 2020

"I took methotrexate for about a year and a half before I took my self off it for about 2 years , I didn't experience much other than it had completely cleared my psoriasis. However saying this when ever I did take it I just felt unwell, I cannot explain how it made me feel but I can still vividly remember it. Due to my skin become increasingly worse, I have been forced to go back on this medication."