Verzenio User Reviews & Ratings

• Jan...
• Taken for 1 to 2 years
• May 24, 2023

For Breast Cancer "I have completed 1 year of Verzenio for stage IIIA lobular breast cancer. While this drug has side effects, I have found it very tolerable, especially after the first 6 weeks. I experienced nausea, constipation, altered food taste, fatigue, and vertigo. These mostly resolved with a dose reduction from 150 mg to 100 mg twice daily. After a couple more months, I was able to increase my dose back to 150 mg twice daily without the return of side effects. My oncologist was very proactive in helping me manage side effects. My blood counts dropped to low normal and have stayed at this point. I have found Verzenio to be a tolerable drug, even if it is challenging the first couple of months. It is well worth taking as it does prolong the time to breast cancer recurrence! I hope that lasts forever for me!"

• Swi...
• Taken for 1 to 2 years
• May 21, 2023

For Breast Cancer "I’ve been taking Verzenio for just over 1.5 years and have about 5 months to go. I'm taking it because I’m at high risk for recurrence. I take 150 mg twice daily. I have diarrhea just about every day, often multiple times per day. Imodium helps, but I have to take that sparingly or I will have the opposite problem. I am exhausted all the time and have very low energy. I have terrible GERD also, but Pepcid has really helped that. I will finish this medication because I’ll do anything to have as much time as possible with my family. I feel the side effects are worth the potential benefits."

• cha...
• Taken for 5 to 10 years
• December 29, 2022

For Breast Cancer "I have been taking Verzenio since it became FDA approved. My numbers were in the thousands, years later, my last number was 41.8. It has extended my life with my family. Being a rare male with breast cancer, they told me I would be lucky to make 5 years. I'm on 9 and going. It's the sole reason, according to my original doctor, that I'm still here enjoying my grandchildren. Like I said, I started taking Verzenio since it came out on day one. I can't say enough how wonderful it has been."

• Gir...
• Taken for 1 to 6 months
• January 26, 2025

For Breast Cancer "Very helpful after lowering the dose from 150 to 100. Was more bearable with side effects. Cancer tumors shrank dramatically. I feel a lot better, still kinda tired on some days, but very tolerable. I don't vomit anymore and less going to the restroom."

• BoB...
• Taken for 1 to 2 years
• December 4, 2020

For Breast Cancer "Have been on Verzenio for 14 months, a dose of 2 pills a day, 150 milligrams. After 6 months, had my first PET scan and my tumor had shrunk 60% and my bone mets were also showing smaller. Had my 1-year PET and Dr. could not see bone mets and tumor had shrunk to around 90%. I have lots more good days than bad, I also take letrozole, still very active, I walk 2 miles 4 days a week, also take one injection of Xgeva a month, so thankful for these treatments."

• Jod...
• Taken for less than 1 month
• May 25, 2023

For Breast Cancer "I was diagnosed with Stage 2B invasive ductal carcinoma, ER/PR+ HER-. I was on Verzenio 100 mg twice a day for 4 weeks, and my liver enzymes went through the roof. My ALT went up to 1077. It's been 3 weeks since discontinuing it, and the liver is returning to normal function. My oncologist wants to try again at a lower dose, 50 mg twice a day."

• C H...
• Taken for 1 to 6 months
• May 21, 2023

For Breast Cancer "Started on Verzenio. At first, I had diarrhea when eating milk products, including small amounts of dairy in any foods. This was at 150 mg twice daily. The diarrhea got worse and would not stop no matter what I ate. It slowed to a stop when I went on the 100 mg. My lungs have a bit of a problem, my creatinine levels are a bit high, and my white count is down. I am tired and need 1-2 naps a day. But I am managing. I am back to work 1-3 days a week. Loving my job. I found Gatorade and Powerade to help along with my vitamins."

• SJM...
• Taken for 2 to 5 years
• July 7, 2024

For Breast Cancer "I have taken Verzenio for five years. Due to neutropenia, my dose has been cut down to 50 mg twice a day. I have a compromised immune system, and my main side effect is fatigue. I am able to tolerate going out in public. This drug has kept my Stage 4 cancer at bay and has kept me alive. I am very grateful to Lilly for their program in supplying the drug at no cost."

• Sar...
• Taken for 6 months to 1 year
• January 27, 2024

For Breast Cancer "Verzenio makes me nauseous when I don't have food prior to taking. I found it easier to take after breakfast, with a smoothie, or after dinner. I tried taking the pill just prior to eating, however, the anti-nausea effect of the food was not as effective. I feel Verzenio contributes to weakness in my muscles and stamina. However, with the same side effects as my aromatase inhibitor, a few other medications, and the possibility of these symptoms also being from prior treatment, it is almost impossible to attribute any one medication or method of treatment as the definitive cause of many symptoms I experience every day. There is one definitive side effect that I can directly attribute to Verzenio, and that is the gastrointestinal issues. The ferocity of the violent, very urgent diarrheal response caused the need to stay on top of how my body responds, and when, which is definitely necessary. It took several months for my body to get past this stage. I used Imodium."

• Rub...
• Taken for 2 to 5 years
• November 12, 2023

For Breast Cancer "My experience has been very good. The med started working for me immediately after I started taking it. My dosage was lowered after about a year due to increased vomiting and diarrhea. But the lowered dose is working great. Very few side effects and little diarrhea."

• Tyl...
• Taken for 1 to 2 years
• August 26, 2024

For Breast Cancer "I am taking 150 mg twice daily and anastrozole. Both medications were started at the same time. Side effects have been manageable but have included weight gain, tiredness, and minor stomach/digestive issues. I have not had to take any Imodium."

• Pet...
• Taken for 1 to 6 months
• July 12, 2023

For Breast Cancer "Stage 2A no lymph node breast cancer dx Oct 2022. Mastectomy only. On Verzenio 50 mg bid and Anastrozole 1 mg daily. For 3 months. Only side effect decreased WBC and neutrophils. Run 3 miles daily, vitamins, psyllium seed and vegetarian diet, meditation, PEMF therapy. Doing great so far. As long as neutrophils stay within low normal. Verzenio my choice instead of chemotherapy."

• Alf...
• Taken for 1 to 6 months
• January 8, 2024

For Breast Cancer "I've been taking this drug for 4 months with Letrozole for BC liver mets. I take 150 mg twice a day. I had terrible side effects - severe diarrhea, sore eyes, and fatigue, which improved with time. However, I had to have a 3-week break due to another illness, and now it feels like starting again. Hopefully, it will ease again and become more manageable, although my eyes never improved (it's a rare side effect). The great news is that my tumors had shrunk by about 25% after 3 months, so I'll keep going!"

• Deb...
• Taken for 1 to 2 years
• May 9, 2024

For Breast Cancer "I started on the highest dose, and now I am down to 50mg twice a day. I take weekends off. I have very few problems with it now. I have been on it for a year. It is in my spine and pelvis. Recent scans show no activity in the pelvis and no change to my vertebrae. I will stay on it as long as I can. I believe it is helping me."

• Rob...
• Taken for 1 to 2 years
• February 18, 2024

For Breast Cancer "It has made me very tired. I’ve gained weight. I only had a little bit of diarrhea, but did have constipation occasionally. My hair has thinned a lot and my nails are horrible! Despite all of this, I think I’ve tolerated the medicine well. I’ve been on it for 15 months at 150 mg twice daily. Only time will tell how well it worked."

• Pat...
• Taken for less than 1 month
• April 25, 2023

For Breast Cancer "It caused damage to the protective cover of my brain, causing memory problems and cognitive abilities. I ended up in the hospital two times. I no longer can take cancer medications or anything that can cause problems with my brain, like anesthesia."

• Kri...
• Taken for 1 to 6 months
• August 5, 2024

For Breast Cancer "Verzenio is the hardest drug I've been on. So many side effects I'm too tired to mention. Reduced to 100 mg, still the exhaustion is the worst side effect. Came off for radiation and felt amazing. Forgot how great I used to feel before this shitty drug."

• Anonymous
• Taken for 6 months to 1 year
• October 29, 2022

For Breast Cancer "Found one sacrum bone met around 1.4 cm in April 2022 since my initial dx of March 2016 lobular cancer HR98%/PR 97% HER-. I started Zometa and Verzenio plus Fasadex injection because I was taking letrozole for 3 years since 2016. Dr. said not to use letrozole again, it has mutation resistant, so change to Fasadex. On July 22, PET scan, my PET scan showed no activity, and also the bone is healing by filling osses. Dr. wants me to take more Vitamin D3."

• aym...
• Taken for 1 to 6 months
• January 11, 2023

For Breast Cancer "Mother has been using it for 4 months so far. Great control on all tumors. Some acceptable side effects such as fatigue, mild anemia, and elevated creatinine levels, but things are getting better with time."

• Anonymous
• Taken for 1 to 2 years
• March 19, 2025

For Breast Cancer "I took the 150 mg dosage of Verzenio twice a day for two years. I experienced terrible, out-of-control diarrhea for the entire time. I would have zero urge to go to the bathroom, and then suddenly had to go so badly that I had mere seconds to get to the toilet. I was very nervous about leaving the house, as there seemed to be no schedule or way to plan for an incident. As a result, there were plenty of 'accidents.' The diarrhea was always the color of the medication - kind of a turmeric yellow - and the accidents permanently stained many pieces of clothing. I have now been off the Verzenio for eight months, and I still have only diarrhea - I haven't had a normal bowel movement in nearly three years. I have not had a recurrence of breast cancer at this point, so hopefully, it was effective. I chose to stay on it at the higher dose because the hope that the drug would work was more important to me than the side effects."

• JNi...
• Taken for 1 to 2 years
• October 19, 2024

For Breast Cancer "I have been prescribed this as a preventative treatment. I’ve just finished 24 rounds. Started on 150 mg twice daily and struggled with diarrhea, lost quite a bit of weight, and had dosage reduced to 100 mg twice daily. This was much more manageable. Fatigue was the main side effect throughout. It peaked at round 22, which then caused another reduction to 50 mg twice daily. My last round was at 100 mg twice daily. The drug was easy to take morning and night. Overall, worth the fatigue to protect me moving forward. 24 rounds seemed excessive when I was told after other treatments, but it has gone quickly, and I did like that I still was checked in regularly through the period. I can’t really comment on its effectiveness as my reason for taking it cannot be evidenced at this point."

• ann...
• Taken for 1 to 6 months
• January 4, 2025

For Breast Cancer "Took for 5 months, beginning of March 2024 to the last week of July 2024. Occasional diarrhea, treated effectively with diarrhea medication. July 2024, began having shortness of breath. Last week of July, went to my pulmonologist. Chest CT done. I had pneumonitis, bilateral. Hospitalized for 2 days. Treated with corticosteroids. On discharge, treated with oral prednisone. Started with 40 mg, then weaned off initially after 4 weeks, then restarted for another 4 weeks. Last dose was the 3rd week of October. Pneumonitis resolved."

• Ano...
• Taken for 1 to 2 years
• April 19, 2025

For Breast Cancer "I had a lot of diarrhea for several months. Then I started taking anti-diarrhea medication at the same time that I took Verzenio, and I didn't have as much diarrhea."

• Tuc...
• Taken for 1 to 2 years
• September 20, 2020

For Breast Cancer "I have been on Verzenio for 14 months. After 2 months, it shrank my tumor by 60%, and after 12 months, bone mets were almost gone. A 12-month PET scan showed no active cancer cells."

• Luc...
• Taken for 6 months to 1 year
• February 19, 2020

For Breast Cancer "Verzenio has worked after my wife’s initial treatment failed and her cancer returned. She had some initial diarrhea, but our doctor adjusted the dose, and now all is going well."