Trulicity and Fatigue: What Users Say (Page 3)

• Ric...
• Taken for less than 1 month
• September 24, 2018

For Type 2 Diabetes "I have just given myself the fourth dose (yesterday). The first two weeks were pretty brutal. Flu-like symptoms, zero energy, gas, and nasty burps. The week after the third dose was much better. The burps come and go, as does the gas. I have tons more energy, almost normal, and sometimes I actually have felt my appetite coming back. I have lost 6 lbs in three weeks and feel like that is tapering off, and that is fine. I have to make myself eat, which is a first in my life. I miss the desire for food, but I have no desire for the bad foods I was eating before, so that is a great thing. I'm going to keep going and see if things continue to taper off. I was on Farxiga previously and spent $5000 to find out (all by myself with no help from doctors) that it was making me incredibly ill with gastrointestinal issues. Glad that is over, and anything feels better than that. Best of luck to all."

• Mag...
• Taken for less than 1 month
• August 27, 2018

For Type 2 Diabetes "I have just taken my second shot of the 0.75. It brought down my morning numbers significantly, within normal range every day. I have had minimal side effects; a little nausea, flatulence, a sense of being too full after a small meal. Quite fatigued the day I take it. Given the good results I've had so far, I will continue unless something significant comes up."

• jes...
• Taken for less than 1 month
• June 23, 2021

For Type 2 Diabetes "I have been on Trulicity, .75 dose as well as Metformin 1000 mg x 2 a day for the last 3 weeks. My stomach feels awful, cramping and severe diarrhea. I am experiencing heart palpitations and chest discomfort. I am also experiencing a lack of energy and have had to call off of work. I know I was told to see how it works, but it hasn’t really done much for my sugar. I may try to wait a bit longer to see if the symptoms subside. I’m definitely making an appointment to discuss my symptoms."

• no...
• January 31, 2017

For Type 2 Diabetes "Aside from all of the stomach issues and fatigue, this is now the second time that a box of the pens has been defective. When you contact the company to report it, they all but call you a liar. I will be telling my doctor to find another med. I use other pens and have never had a problem with them. The secondary issue is now I have used pens ahead of time in place of defective ones, and my insurance will not authorize more pens ahead of time. The drug company did agree to do a one-time replacement of the two pens. Getting off now because this tells me I am on my own in the future."

• Anonymous
• Taken for 1 to 6 months
• September 14, 2017

For Type 2 Diabetes "I have a love/hate relationship with Trulicity. I was taking 1.5 injection weekly for six months. Yes, you'll lose weight because you're nauseated and fatigued. Just the smell of food can make you feel ill. Because of a Dr./insurance situation, I didn't take the dosage for two weeks. I began to feel better, with appetite returning and having energy back. My fasting numbers are up to 100-130 (80-100 when on dosage), but I hope there is an alternative to having to take Trulicity. It was not a good match for me."

• BJa...
• Taken for less than 1 month
• June 15, 2019

For Type 2 Diabetes "Took one dose of Trulicity eight days ago. I’m still very sick to my stomach, and the fatigue is frightening. Needless to say, no more for me. I will say it controlled my sugar very well, but definitely not worth it."

• Tab...
• Taken for 1 to 6 months
• March 22, 2018

For Type 2 Diabetes "I'm a type 2. I'm a 110 lb female. My doctor put me on Trulicity .75 mg and injected me in her office. I did okay with it, fatigued for a few days, not too bad. Third week bumped me to 1.5 mg. Literally, within a half-hour, I became so dizzy and nauseous I was fighting back vomiting. It wasn't an allergic reaction, just felt like a terrible flu. Neck and back pain and aches and pains all over. Injection site wasn't irritated and made a lump under my skin. I think the dose was way too high for me. I'm taking the same amount as a 300 lb man would take. It's all a big money pit. It did help lower my A1C, but only because I couldn't eat and total loss of appetite. I'm extremely thin as is, so losing weight was not a good goal. I'll never take it again. Couldn't go to work either."

• Lam...
• July 23, 2017

For Type 2 Diabetes "My doctor gave me the injection in his office. I take no other meds for my diabetes (type 2). A1C was around 10, triglycerides were 3000, cholesterol was 541. I also have acute pancreatitis and later read this med was not good for this pre-existing condition. That night after the shot, I became ill, lower back pains, an extreme full feeling in my tummy, nausea, and dizziness. He also prescribed Tricore to get my triglycerides down. I have been sloppy with my diet, and I know what I need to do to change my eating. I honestly can say, after reading other reviews, that this drug scares me, and I won't be buying more. 629 drug interactions I read about on another site and me being fatigued and in a fog for three days, I say no more."

• Hal...
• Taken for less than 1 month
• November 25, 2021

For Type 2 Diabetes "I started on Trulicity 1.5 mg 2 1/2 weeks ago. It was awful. The side effects started the next day after my dose. I was freezing cold with shaking chills, nausea, irregular heartbeat, severe constipation, extreme fatigue, and body aches. I felt like I was going to die. I almost went to the hospital, that’s how bad it was. I could hardly get out of bed for three days. After 2 1/2 weeks, I’m still having lower abdominal pain. The other side effects have subsided, but it took a long time. I also had itchiness, rash, and back pain. I wish I could’ve taken this, but the side effects were just way too bad. I couldn’t stand feeling like that."

• Con...
• June 2, 2015

For Type 2 Diabetes "This is week 4 for me, and I am wondering why I am continuing to take this medicine. Yes, it helps me lose weight, but is not enough to keep my sugar levels down long. Seems to wear off after a few days, I have to take my other daily Lantus shot to keep my sugar levels down. Also, I don't like the feeling when I combine the two: feel weak, fatigue, tingly. Looking for a new endo doc. Do not feel this is the right solution for me. I do not like the unknown side effects of Trulicity. I will take this until I find a new doctor. Motivating me to lose weight on my own, with proper eating and exercise. I will be off this soon. Lantus seems to do the job, I don't understand why the endo put me on this, other than wanted me as a guinea pig?"

• MLV...
• Taken for 1 to 6 months
• June 5, 2019

For Type 2 Diabetes "After 3 months on Trulicity for type 2 diabetes, I've gained 10 lb. My stomach hurts/cramps. The worst is the fatigue, I've not been physical in 2 months, which would account for the weight gain. My daily insulin use is the same or a bit higher since I'm not able to leave my porch, the yard work and lake activities are non-existent using this drug."

• Anonymous
• July 13, 2019

For Type 2 Diabetes "So happy to read everyone's comments! Due to state insurance, I had to be taken off Victoza, which worked great and made me feel great, and I was swapped onto nasty Trulicity! I had gas, bloating, diarrhea, and felt agitated and lethargic, fatigue! Horrible! My numbers were out the roof to 269!"

• RN...
• April 26, 2018

For Type 2 Diabetes "I started taking this drug a couple of months ago. At first, it wasn’t too bad-a little nausea and decreased appetite. The more I took it, the worse the symptoms became. Severe vomiting, diarrhea, and cramping, weakness, and fatigue. At first, I thought it was just a virus, but it happened every time I took the drug. The vomiting and diarrhea have been so severe lately that I have had to miss work because of it. I will never take this drug again!"

• mee...
• Taken for less than 1 month
• March 23, 2018

For Type 2 Diabetes "Started taking Trulicity March 14th (Wednesday). The next day I wasn't really hungry but went to cycle class, and I felt nausea, but after class got something to eat. Then, 40 minutes later, my stomach was hurting so bad, then I went to the restroom and felt better. The next morning I had to make myself eat breakfast (Special K), ate about 4 bites, and I didn't want any more. So my only side effects are some nausea, very, very lite abdominal pain, and really have no appetite. I have to make myself eat and drink water, and some fatigue from time to time."

• Swe...
• April 5, 2018

For Type 2 Diabetes "So I went to see a new diabetes specialist regarding my blood sugar levels. She recommended that I take a drug called Trulicity. I took the first three doses. Then on the fourth dose, everything changed. The first change I felt was having extreme nausea. Second was pain in my abdomen. Third, the pain and aches that I already had were amplified by 100. A slight case of trigger finger I had now hurts consistently. I feel extremely fatigued and tired. I called the specialist a week ago and she said to stop taking it. My body is still extremely achy. My hands are still sore, and I cannot type as long as I did before without having to take a rest or push through the pain. My blood sugar levels are also drastically different. Before I was off the Trulicity, my blood sugar was still a little elevated, but not horrible. Normally it would be in the upper to mid-100s. Since stopping Trulicity, my sugar levels have been in the upper 200s to over 300."

• Kay...
• Taken for less than 1 month
• February 8, 2022

For Type 2 Diabetes "I started Trulicity at 9 AM on 2/6/22 and was very hopeful that I'd be able to tolerate it. No such luck. By 6 PM, I was experiencing a very rapid heart rate (165 bpm, and it's gone as high as 178), and my blood pressure was 158/105. I'm already on 20 mg of lisinopril and was having ideal BP. Every time I'd move, I'd feel so horrible. Heart beating out of my chest, fatigued, heavy breathing. I also can't eat. Yesterday, I had to force a snack cup of jello and some chicken broth after 5 PM because I hadn't eaten. I have waves of fullness and nausea every 5 minutes or so. I talked to my endocrinologist yesterday, 2/7/22, and was prescribed a beta blocker for my heart rate and blood pressure. It seems to be working, but I don't like that I need it. Hopefully only 5 more days of this... I know people Trulicity has worked wonders for, I'm just not one of them. If your heart rate or BP goes up significantly, please call a doctor, it is listed as a serious side effect, and a week is a long time to wait."

• Min...
• Taken for less than 1 month
• July 13, 2021

For Type 2 Diabetes "I have been on Trulicity three weeks, and the nausea and stomach pain are gut-wrenching. HOWEVER, my numbers are great, and I have lost ten pounds in two weeks. I can't eat as much, and whenever I do eat, I feel sick, but I'm still hopeful. I do have lots of fatigue and had to get on Zofran to try and control the nausea. I am hoping this changes after a few more doses. I don't want to give up on this medicine, especially since my insurance pays for the majority of the cost."

• EJa...
• Taken for 1 to 6 months
• May 12, 2021

For Type 2 Diabetes "After 4 weekly injections, my doctor took me off of Trulicity. My blood glucose numbers were going down nicely; I lost weight, and it was an easy medication to take. BUT... first week: overwhelming nausea and fatigue; constant belching. Week two was much better. Weeks 3 and 4, exactly 42 hours after injection both weeks, extreme watery diarrhea began and continued for the next 15 hours. Two hours after the onset of diarrhea, violent vomiting began, and hard heaving continued after my stomach was empty for about 4 hours, followed by hours of nausea and fatigue. I wish I could have kept using this, but my side effects were too bad."

• KTa...
• Taken for 2 to 5 years
• May 11, 2021

For Type 2 Diabetes "I’ve been on Trulicity for two years. Initially, it was wonderful. I lost 40 lbs and had a very small appetite, which made it easy to keep it off. My problem is that if I fail to take it at the same time each week, I am down with nausea and fatigue for at least a day. I tried going up to a higher dose and was sick the entire month. I can’t find anything that works better."

• Ran...
• Taken for less than 1 month
• July 23, 2021

For Type 2 Diabetes "My diabetes nurse pitched Trulicity to me as a weight loss injection, and in some ways she's right because I did not want to eat a thing with all these side effects. Three days after my first injection and the side effects are absolutely dreadful. Explosive diarrhea, vomiting, abdominal pain, and fatigue (I already have CFS!). Will not be taking a second dose, no matter how much my doctor wants me to try and wait out the symptoms."

• Joh...
• Taken for 1 to 6 months
• July 6, 2021

For Type 2 Diabetes "Marginal works at reducing my BGL and too many side effects to consider staying on Trulicity. I have had headaches, constipation, fatigue, and an overall feeling of sickness since I started on 1.5 Trulicity a month ago. After 4 treatments, I am done with trying this as a means to help my type 2 diabetes. Personally, I just concluded that Trulicity made me feel worse than any positive effect it had on my diabetes."

• Nor...
• Taken for 1 to 6 months
• April 20, 2021

For Type 2 Diabetes "For the first two weeks of using Trulicity injection, I suffered nausea, joint pain, fatigue, and severe constipation. After this, all the side effects went except for the severe constipation. I was prescribed Laxido, but still no movement after a week. Then I decided to experiment - I squeezed an orange and added the pulp to a Laxido powder with 125 ml of warm water. Number one, it tasted better, and after 24 hours, it worked a treat. Now managing very well. I finish the 3-month trial in two weeks to see if it is working on my diabetes, so will update this then."

• Dbj...
• Taken for 6 months to 1 year
• July 5, 2021

For Type 2 Diabetes "Trulicity was given to me in 2020 to stabilize my blood sugar ups and downs. I have hyperglycemia, so it worked well at first. After taking the .75 for 3 months, it helped lower A1C back to 5.0. I know everyone is different with side effects, but she has upped my dose to 1.5, and the pain, gas buildup, was not good. My acid reflux medication stopped working as well, and I had sores in my mouth, rash, fatigue, cough, and sleeplessness."

• Vic...
• Taken for less than 1 month
• December 25, 2020

For Type 2 Diabetes "Been on Trulicity for 2 weeks now, feeling spacey, brain fog, and very sleepy, plus fatigue with GI upset. Sugar went down from 300s to 150s. I will try to tolerate side effects for now. Wish me luck."