Trulicity and Diarrhea: What Users Say (Page 2)

• Kim...
• Taken for 1 to 2 years
• September 13, 2019

For Type 2 Diabetes "I have spent the last week in a living nightmare - like I've never known. Trulicity 1.5 has been working for 2 years with little or no side effects. A1C dropped from 9.5 and stayed at 5.7. Good and steady. Right? It has curbed my appetite, I lost about 25 lbs, but need to lose more. I wasn't eating much, but hit a plateau. So, my doc talked me into increasing to 1.5. One shot. That was Friday night. No appetite since then. When I say no appetite, let me be clear. The thought of food makes me want to puke. I have not eaten anything solid in almost a week... oh, and starting Monday night, the worst searing pain in my abdomen I have ever experienced. Diarrhea, pain... no food... oh wait, I get it. This higher dosage will make me never eat again. That is the goal. Gotcha. Glucose between 72 and 94... so there is that."

• Sue...
• Taken for 6 months to 1 year
• September 23, 2019

For Type 2 Diabetes "I’ve used Trulicity for close to a year. I’ve experienced indigestion and diarrhea consistently every time I eat anything fried, so I try to steer clear. The one odd thing that I’ve found associated with the timing of starting Trulicity is extreme hair loss. Very scary at my age, at any age for a woman. Has anyone noticed this problem? I’ve eliminated every possible thing in my life that it could be, and the timing is right."

• Jay...
• Taken for less than 1 month
• May 5, 2019

For Type 2 Diabetes "I started on Trulicity last Monday, and I've been sick as a dog ever since (it's now Saturday night). Within an hour of injection, I was retching at the porcelain altar. Sick to my stomach and stayed in bed the whole next day. Wednesday, I felt good enough to go to the gym and eat lightly, although I still felt slightly nauseous. Wednesday night, I woke up retching again. Sick all day Thursday, and I had a charity dinner to attend that night. Couldn't eat the dinner and went out in the lobby while others dined. Totally miserable! Friday, still sick and weak, foggy brained. Had an appointment with an attorney I was late for because of anal leakage in my khaki pants! Friday night and all day Saturday, I had intense stomach cramps and black liquid diarrhea. Leakage again, had to change pants. Drank half a bottle of Kaopectate, but can't stop diarrhea. I have a concert tomorrow, I don't know if I'll be able to attend."

• Kel...
• Taken for less than 1 month
• November 18, 2018

For Type 2 Diabetes "I realize everyone's experience is different, but I was not prepared for this. Nausea, vomiting, and diarrhea 24/7. I have never felt so horrible in my life. It's only been 3 weeks. I can't live like this. I am missing work because I need to get to a bathroom constantly. I've lost 15 pounds. My aunt takes the same dose, and she has had no side effects at all. I am just praying it works its way out of my system soon."

• Bea...
• Taken for less than 1 month
• January 26, 2019

For Type 2 Diabetes "One year ago this past October, on my 45th birthday, I was diagnosed with DM 2 out of the blue. As it would turn out, I am one of those poorly controlled individuals. I was started on Metformin 500 mg twice a day, then Glipizide ER 5 added daily with fasting still 450. In December, my readings stayed over 600. This is when I was introduced to 'Trulicity.' Week 1, not bad. Week 2, rougher, pain in the pancreatic region/kidney. More intense waves of nausea/diarrhea. Tolerating. Week 3, debilitating. Nausea, mass diarrhea, which was crippling. I have lost 10 lbs since starting this med on January 7th. My blood sugars have improved, 170s...the lowest it's been in a year, but I have to question, is it the Trulicity or the fact that I can't eat, and when I try, I'm puking my guts out? This has been the worst week yet, so I am done. No more Trulicity for me. I would rather suffer the consequences of poor control than to have an 'improved' blood sugar that is still non-therapeutic and have no quality of life."

• Anonymous
• Taken for 1 to 6 months
• January 2, 2016

For Type 2 Diabetes "I have been on Trulicity for 12 weeks now. The first 2 weeks I was on the 0.75 mg injection, then went to 1.5 mg. The first 2 days after my injection, I am very nauseated and usually vomit around 4 a.m. My issue is indigestion, and of course, nausea and vomiting. I have found that eating no greasy foods, dairy products, and no eating past 6 p.m. has helped me tremendously in cutting down on the indigestion and nausea and vomiting. My blood sugars are doing great, and my A1C is coming down. I, like so many others, do not have an appetite, and I experience diarrhea often. I have lost 34 pounds so far. I am very happy with the medication, and just learning what you can and cannot eat is the key factor."

• Ano...
• Taken for 6 months to 1 year
• January 30, 2020

For Type 2 Diabetes "I’ve been on the highest dose of Trulicity for about a year. It was added to my Metformin regimen to help lower my sugars. Never really started seeing weight decrease until the doc added Jardiance to the mix this summer. I do notice stomach issues that others have mentioned, mostly severe cramping with diarrhea. Not an everyday occurrence or even weekly, so it’s tolerable. Have lost 40 lbs in 3 months with little to no exercise and no change in eating habits. Last A1C checkup, I was at 6.2, which dropped down from a 7.8 in 3 months."

• LCa...
• Taken for 1 to 6 months
• December 17, 2019

For Type 2 Diabetes "Diagnosed in October with type 2 diabetes, started Trulicity. Blood sugars normal. Developed back pain and fatigue. Injections on Fridays, day after Thanksgiving, diarrhea, nausea, burps like nasty sulfur x 4 days, very sick. To ER Dec 10th, chest pain, back pain, diarrhea, nausea. Labs normal for heart, pancreas, and liver. Thought severe flare of my GERD, saw PCM Thur 12th, increased Nexium, & more meds for stomach and diarrhea. Inject Friday 13th, sick again Sat & Sunday. No more Trulicity for me. Missed too much work and sick the past 3 weeks."

• Net...
• Taken for less than 1 month
• January 25, 2019

For Type 2 Diabetes "Had 1 dose. The first day was good. But by Thursday, I was burping that gas smell. Had gas-like pain on the right side of the body, diarrhea, loose stool, the worst. Couldn't sleep, now at the ER because I feel horrible. Haven't eaten much of anything. Won't be taking this again, hate the side effects early on."

• Net...
• Taken for less than 1 month
• January 25, 2019

For Type 2 Diabetes "Had 1 dose. The first day was good. But by Thursday, I was burping that gas smell. Had gas-like pain on the right side of the body, diarrhea, loose stool, the worst. Couldn't sleep, now at the ER because I feel horrible. Haven't eaten much of anything. Won't be taking this again, hate the side effects early on."

• Pri...
• Taken for less than 1 month
• December 15, 2020

For Type 2 Diabetes "I was on Trulicity for three weeks, and what a horrible three weeks this has been. I have had diarrhea for the last three weeks and started vomiting as of Saturday, December 12th, and I called my doctor up, she took me off of Trulicity ASAP, and now it's a waiting game for these awful side effects to go away. Eating little bits here and there and pushing in fluids, but hard to keep down. I will never go back on Trulicity ever again."

• Mrs...
• Taken for 1 to 6 months
• July 24, 2020

For Type 2 Diabetes "Been on Trulicity for a few months for pre-diabetes, ended up in the hospital with severe vomiting, diarrhea, and stomach pains. No one figured Trulicity, now, 3 weeks later, same episodes. I am done with this!!!"

• Lad...
• Taken for 6 months to 1 year
• September 22, 2016

For Type 2 Diabetes "I started on Trulicity in April of this year. At that time I weighed 352# and had been diagnosed as a new Type 2 diabetic. My PCP had tried a three-month course of Metformin and it dropped my 'number' a whopping 0.2. He recommended Trulicity and started me immediately on the 1.5 dosage, giving me the first injection in his office. From the first dose, I have had virtually no side effects. On occasion, I will get slightly sick to my stomach if I eat too much, or have a bout of diarrhea if I consume too many carbs, but that's it. This is mid-September and I have lost 57# without dieting or exercising or anything. Naturally, as the weight comes off, I feel more like moving around and doing things, but IMHO this is a miracle drug!"

• Mel...
• January 23, 2017

For Type 2 Diabetes "In the beginning, I had some diarrhea and belly issues...that subsided after a few days. I only have one reaction to it now, and that is I get an itchy hive at the injection site about 12 hours after I use it. It goes away within a few hours, I'm not worried. It has lowered my A1C's like a charm. I LOVE this injection, I feel fuller longer, I no longer crave sugar, I've lost 25 pounds without really trying, and I have no side effects at all. One tip...to ease the burn of the shot, I put it in a cup of warm water so it comes up past room temperature. Also, I use the coupon on the website to pay for it."

• Ter...
• Taken for less than 1 month
• December 30, 2020

For Type 2 Diabetes "I started Trulicity .75 on a Monday morning. I can say I just felt a little nauseous. Oh, but when Tuesday came, it was the worst day ever. I literally felt like my life was slipping away! There was abdominal pain, diarrhea, and vomiting-constant vomiting for a good 5 hours. It’s like it was trying to make me vomit until nothing was left, and when there was nothing left, I was vomiting bubbles! Literally bubbles and saliva. The burps are horrible, smells so disgusting. I guess I will play the waiting game to see what the rest of the week holds, but I am definitely not taking this again. Nope. If I would have stayed on, I’m pretty sure I could have lost weight, but nah, not worth it."

• Kat...
• October 13, 2016

For Type 2 Diabetes "I took my first dose of Trulicity yesterday. Never used any diabetes drugs before. There is definitely a decreased appetite. But to keep sugar levels steady, you have to eat a little a few times a day. I would say every 2 hours. Nuts are a good idea, small apple pieces, cut-up chicken, yogurt, nothing heavy. People have diarrhea because you should not have fatty and fried food at all. The only side effect that I have is a sudden feeling that I am going to pass out, following a panic attack. I guess my body is adjusting. I'll give it a try for a month. I appreciate everyone's input, it's so helpful."

• Deb...
• Taken for less than 1 month
• May 23, 2019

For Type 2 Diabetes "If you want to feel like you are dying, this Trulicity is the drug for you! This drug is a disgrace and shouldn’t even be allowed to be on the market! SERIOUSLY! Worst medication I have ever taken! Pray they don't delete my post! I took this drug this morning, given to me by my doctor. I have had severe, nonstop, excruciating pains throughout my stomach, vomiting, nausea, and diarrhea! I looked over side effects, and it says exactly that - plus you can get deadly thyroid cancer. Do yourself a favor and REJECT THIS DISGUSTING, DEADLY MEDICINE!!"

• Bec...
• Taken for 1 to 6 months
• January 23, 2017

For Type 2 Diabetes "This was my 4th week taking Trulicity .75. The 1st two weeks went okay, the 3rd week I started having severe pains in my stomach, severe nausea, hives, diarrhea. The 4th week was the same but worse, I broke out in hives from my head to my feet, had welts all over me. I just got back from the hospital last night because of it. And it's still doing the same thing the next morning, I wake up with severe stomach pains, nausea, I belch and it tastes like rotten eggs, diarrhea, and the itching, hives everywhere! Ended up having to take prednisone and Benadryl for the hives rash, Zofran and acid reducers for the sickness and vomiting. It makes food lay in my stomach and doesn't let it digest. Please do research on this medicine if it is offered."

• JRa...
• Taken for 6 months to 1 year
• December 14, 2018

For Type 2 Diabetes "I have been on a controlled double-blind study for some six months now, not knowing for certain that of two possibilities, I am taking a high dose (1.5) or a lower one (0.75). Because of the sometimes severe side effects, I have to conclude it is the higher dose. I have lost a good deal of weight, and my A1C has dropped from 7.5 or so to 6.7. That's the good news. The bad news is that, like so many other people, I have had really unpleasant side effects, and these seem to be getting worse over time. They include constipation, diarrhea, stomach cramps, awful-tasting belches frequently with a burning acidic taste as well, bad gas, and a more or less constant low-grade nausea malaise."

• Cat...
• March 8, 2017

For Type 2 Diabetes "First week - I was cold all the time, and I'm never cold. I had flu-like body aches. I had nausea after the first day. By the fourth day, I had vomiting and diarrhea for about 8 hours straight. Today is one week after the first injection, and my stomach is still not the same. I will NOT be taking another injection. Also, for several days, horrible belching, a rotten egg smell."

• cat...
• Taken for less than 1 month
• January 16, 2016

For Type 2 Diabetes "I have taken a 1.75 mg shot of Trulicity, and I'm going to beg my doctor to take me off of it. I was nauseous from day 2 onward, and today (7 days later), I'm vomiting, have explosive diarrhea, and horrible, foul belching. This is the same exact reaction, down to the belching, that I had while taking Metformin. If you are taking Trulicity and Metformin, I'm not sure how you are even alive. My A1C, tested twice in the last 6 months, is 6.5, and that was while taking Januvia, Pioglitazone, and Farxiga. My doctor replaced the Januvia with Trulicity to help improve my daily high readings. Today is shot day...not happening. As I type, I'm about to puke..."

• Mik...
• November 16, 2018

For Type 2 Diabetes "OMG... I thought it was just me, but I have to agree with many others. Although it has lowered my A1C, the side effects are horrendous. The worst stomach pains and gas cramps with diarrhea for 3 days after I take my injections on Mondays (1 per week). And thank goodness for that. I couldn't do two injections in a week, I'm already feeling so down and out and lousy for 3 days. It takes me those other 4 just to recover. No pain, no gain. Well, not my idea of losing weight and sitting on the toilet for the next 2 days with stomach pains and gas pains and cramps. Not what I had in mind. I never knew my stomach made that many sounds. Not to mention the worst heartburn I've ever had in my life, like burning my esophagus right out of my throat. I'm calling my doctor. I might not have lost weight on Metformin, that was fine to me. The nausea from Victoza was bad, it's not even close to how Trulicity makes me feel. Those of you with good results and no side effects, God bless you. I just can't say the same."

• Deb...
• Taken for 6 months to 1 year
• October 24, 2017

For Type 2 Diabetes "It's been 4 months since my last post as I wanted to give it a few months to see how this was going to work. So, I have been on Trulicity for six months now with Metformin. When I hit the five-month period, the diarrhea, gas, and sulfur belching finally subsided. I no longer have any of those side effects. However, I still haven't lost any weight at all, but I think that was because when I first started Trulicity, I was taking it with Glimepiride, and that one has a side effect of weight gain, so I think the two meds were fighting each other, lol. I have been back on the Metformin with Trulicity for about a week now, so we will see what this does. I was diagnosed with stage 3 chronic kidney disease (CKD 3), so I am watching my diet closely."

• No ...
• Taken for less than 1 month
• February 8, 2016

For Type 2 Diabetes "Omg, I have been sick since day one of taking this shot. I do not recommend it to anyone! Unless you like to vomit and have diarrhea 24/7. BTW, that's how you lose weight, you can't eat or stay off the toilet. No, no, no more shots for this lady."

• Fru...
• Taken for less than 1 month
• August 14, 2019

For Type 2 Diabetes "I was doing fine on Trulicity with awesome glucose levels. 3rd week in and 3 days after the injection, I was sick. 5 days later and I still can't keep anything but a few crackers a day down. In 2 days, I lost 10 pounds. I have missed a couple days of work (thank goodness this started on the weekend), but will likely have to stay home at least another day. Uncontrollable diarrhea at night, spending the night in the bathroom, sitting on the toilet and trusty ol' trashcan in front of me. 100% miserable and I do not recommend."