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Amoxicillin and Nausea: What Users Say

Brand names: Amoxil, Apo-Amoxi

Nausea: mentioned by 29 users (7.9%)

Based on user experiences from 366 Amoxicillin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 13.1%
nausea 7.9%
pain 7.4%
headaches 6.8%
tiredness 6.0%
upset stomach 5.2%
yeast infection 4.4%
swelling 3.8%
vomiting 3.8%
rash 3.6%

Reviews for Amoxicillin

Commonly mentioned side effects
  • Bia...
  • Taken for less than 1 month
  • June 25, 2016

For Bacterial Infection "I'm taking it for my gum infection, 500 mg caps 3x a day. The first two days on the medication, the side effects were pretty bad: extremely dizzy, sleep disturbance, headache, super strong appetite, dysphoria, severe indigestion, and extreme nausea. I'm now on day 3 of 7, and my mouth pain caused by an infection in my gums is gone. I'm still experiencing side effects, but they are at a level 3 or 4 instead of a 9 on the first day. I am so grateful to have found this new dentist. Another dentist gave me a different antibiotic a few months ago for the same issue, and it didn't work at all. I really hope this one fully gets rid of the infection. I can't believe how fast it worked!"

10 / 10
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58 Report
  • Amb...
  • May 27, 2020

For Urinary Tract Infection "I’ve taken Amoxicillin many times for a UTI. It gives me a good amount of relief within 6-8 hours. The burning sensation and the bladder spasms usually subside within that time frame. I don’t experience many side effects except for occasional mild nausea and an annoying yeast infection. Those side effects are very common. I’ve also taken this for tonsil issues, and it helps tremendously. There aren’t many antibiotics I can take, but this is one of my favorites for my lupus-induced UTIs."

7 / 10
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33 Report
  • mil...
  • Taken for less than 1 month
  • November 23, 2016

For Urinary Tract Infection "Only used this to cure my UTI so it wouldn't spread to a kidney infection. But the side effects are absolutely horrific! I can't deal with this much longer. I'm supposed to take 500 mg/3x a day for 7 days, but I'm cutting it short. I'll do it for 5 days because it's day 3, and I already want to stop it. My side effects: • All day long nausea • Extreme constipation • Abdominal cramping/pain from the gas trapped and constipation • Difficulty fluctuating • NO appetite whatsoever, every food sounds disgusting and hard to eat • Anxiety and fear mixed with deep sadness • Fatigued and weak • Feeling like I'm slowly dying but trying to make it through each day, day by day • Debilitating - I hardly want to go out and do anything, need to sit out a lot."

1 / 10
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93 Report

Frequently asked questions

  • Lau...
  • Taken for less than 1 month
  • May 7, 2020

For Bacterial Infection "Have IBS, recently got worse, so was given this antibiotic in case I had an infection. Felt fine day 1, day 2 began to feel nauseous, abdominal pains, acid reflux, extremely tired, loss of appetite, headache, and feeling very ill in general. I was taking 3x 500g every day but only managed to get to day 2 till I stopped. Wouldn’t recommend this antibiotic if you already have stomach problems!!"

1 / 10
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33 Report
  • Nic...
  • June 9, 2016

For Bacterial Infection "This drug was really effective in getting rid of my infection, but the side effects were difficult to deal with. The tablets made me so exhausted I really struggled to stay awake all day. My eyes would droop at my desk, and I felt lightheaded and dizzy. I found it extremely hard to concentrate. I had to leave work early taking this tablet because I could not focus, and many times, when my colleagues helped drive me home, they had to help me walk to the car because I was so weak and unfocused I couldn't walk in a straight line. I also felt nauseous for most of the day and had mild stomach cramps. It was wonderful for the infection I had, but it was the hardest week coping with the exhaustion and drowsiness."

3 / 10
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45 Report

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  • JJE...
  • Taken for less than 1 month
  • October 2, 2013

For Middle Ear Infections "This medication works amazingly for ear infections. I have had more ear infections than I can count in my life, both as a child and an adult. I have had ruptured eardrums, double ear infections, tubes, and surgery to repair my eardrums. This medication has always relieved symptoms. For mild to moderate infections, it starts relieving pain in 12-48 hours (but finish the whole prescription or it will return), and for severe or ruptured eardrums, it can take up to 5 days, but hey, it does the trick. Just take ibuprofen around the clock too, as it will speed up the process due to anti-inflammatory properties. I get nausea with this medicine, but only when I haven't eaten or am very overtired, and I always get a yeast infection. The doctor can prescribe medicine in advance for this."

9 / 10
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34 Report
  • Cha...
  • July 7, 2021

For Middle Ear Infections "I was diagnosed with otitis media. It’s been 9 days. On the first day, I lost hearing in my left ear. On the second day, I started experiencing pain and went to the ER. The pain was getting severe, and now I had discomfort in my right ear. It was so severe, it radiated to my jaw and my neck. The doctor prescribed me 7 days of amoxicillin (3 times a day) and to take ibuprofen. It took 3 days for the severe pain to subside. It still feels like my ears are full, and I’m extremely irritable. I went to the doctor yesterday (day 8) as there has not been much improvement since the pain subsided and I was almost done with my prescription. She prescribed me an extra 4 days of amoxicillin and to take Sudafed. The Sudafed helped relieve some of the pressure in my ears. The infection is very much still there. In my 9 days, I had pain, nausea, difficulty eating, loss of appetite, and off and on my throat feels sore. I am so over this! The amoxicillin worked a bit, but I am nowhere near feeling 100%."

3 / 10
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14 Report

More FAQ

  • AZ ...
  • Taken for less than 1 month
  • August 28, 2020

For Urinary Tract Infection "I thought amoxicillin was pretty mild. I asked for it when my urologist prescribed a Cipro-family antibiotic (I think those are really dangerous!)... wrong. I took the amoxicillin 500 mg 2X/day for 8 days and had to stop. It seemed to stop my UTI (first one ever and I have been on catheters for 2 years), but I didn't expect the side effects of rapid heart rate all the time, anxiety from low grade to intense most of the time, it made me feel weak and nauseous, guts in turmoil, eating anything made it worse, so I had to stop. I had no idea this drug had those side effects for many! Avoid!"

3 / 10
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18 Report
  • Eve...
  • July 7, 2017

For Tonsillitis/Pharyngitis "Had symptoms such as swollen gland on my neck, sore throat. Doctor prescribed amoxicillin 500 mg (to be taken every 8 hrs). Got so much better after three days after taking amoxicillin! But do keep in mind, if you have any symptoms such as rashes, stomach upset, or nausea, stop taking amoxicillin because you might be allergic to this antibiotic."

10 / 10
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22 Report
  • Jon...
  • Taken for less than 1 month
  • July 12, 2019

For Bacterial Infection "Amoxicillin worked great. Taking probiotics daily with antibiotics is a must to avoid all the stomach side effects (since they kill bacteria, antibiotics can kill the good bacteria in your stomach that helps digest food-hence the nausea and diarrhea, etc.) If you don’t have probiotics, at least eat some yogurt daily. Continue for a week after the antibiotic course is done."

9 / 10
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16 Report
  • Gan...
  • Taken for less than 1 month
  • August 6, 2020

For Bacterial Infection "Had a nasty tooth infection from an untreated wisdom tooth and felt like it was going to be the end of me. Didn’t handle the infection in time, had nausea, abdominal pain, the works. (Hence, felt like death). I’m 115 lbs, and they put me on 875 mg 2x a day. The first night I could feel the difference! Amazing stuff!"

10 / 10
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12 Report
  • Anonymous
  • June 19, 2012

For Middle Ear Infections "Although the swelling in my ear has gone down greatly, I'm four days into treatment and still in pain, and my ear will not drain even though I can feel the fluid. This medicine is making me feel VERY ill: nauseous, dizzy, loopy, and very anxious."

6 / 10
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25 Report
  • not...
  • May 2, 2016

For Dental Abscess "I got my wisdom teeth pulled two months ago and got put on antibiotics, had no problem with it at all. Now, two months later, I'm on amoxicillin because I need a root canal treatment, and I keep feeling a lump in my throat and pains in the front of my neck down to my collarbone. Sometimes my ears will hurt, or my eyes will hurt, or I'll feel like I have a headache. I've never been allergic to medications before, but I've been taking this for two days now and feel awful. I go in for my RCT tomorrow and will have to ask my endodontist about this, but I'm almost sure that it's the amoxicillin causing this. I just wish I wasn't in pain anymore."

5 / 10
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26 Report
  • Anonymous
  • January 29, 2018

For Dental Abscess "I started taking amoxicillin immediately. My dentist prescribed it for a toothache. I take 1 twice a day for 10 days. After day one, the pain went away, but I had diarrhea, and I felt very nauseous. Also, I had fever and chills. By the end of the night, I had vomited twice. Day two, I just took a half a pill and still felt dizzy and light-headed. I’ve taken this medication before in the past, and I do not recall this kind of problem. But it knocked out the pain."

6 / 10
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14 Report
  • Mom...
  • Taken for less than 1 month
  • November 8, 2018

For Dental Abscess "This drug was prescribed by my dentist. I got a root canal, and he said it was to get rid of the bacteria. The first few days, I had a migraine and nausea. I also got a yeast infection. I finished the treatment, but I would not take this again unless I really had to."

3 / 10
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12 Report
  • HWa...
  • Taken for less than 1 month
  • September 25, 2021

For Urinary Tract Infection "I had a minor UTI and was prescribed a 5-day course of 500 mg 3x a day. Originally, my doctor wanted to give me Macrobid, but that always gives me nausea, so I asked for something different. I think it was a mistake since the amoxicillin didn't seem to help much. To start with, my symptoms were extremely mild, mostly, it was urgency to go when I was trying to sleep and a bit of ache down below. Amoxicillin helped a bit with the symptoms, but after my 5-day course, I could still feel the infection lingering. I gave it a few days to see if it was just my body recovering, but within 3 days of finishing, I was getting up every 10 min before bed again. I scheduled a urine culture, and in the meantime, took Azo Defense (which actually reduced symptoms FASTER). I suppose if I had a 7 or 10-day course, it might have cleared the infection, but I also didn't like the side effects. I felt like I had a rapid heart rate all the time and kept debating if I should go to the ER."

3 / 10
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6 Report
  • Oti...
  • Taken for less than 1 month
  • June 15, 2022

For Middle Ear Infections "Otis Media, with a perforated eardrum. I was nervous to take this medicine due to the side effects of nausea, vomiting, and diarrhea. I have GERD, so I was worried I’d be too sick to work or do much of anything. I’m on day four of taking two 500 mg amoxicillin pills twice daily. I have not vomited or felt too sick, just some heartburn here and there. I have had more frequent bowel movements, but nothing too crazy. My ear is not in pain and feels less full, but there’s still some gunk coming out of it. I’ll finish the 10-day course and hopefully the infection will be gone by then. Oh, and ladies, the vaginal itching side effect is very real."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • April 4, 2023

For Dental Abscess "This medication is an 8/10 for me. It worked wonders. I was in excruciating pain as I had an abscess in a tooth caused by a cavity that needed a root canal. It took 3 pills to finally have some relief. My prescription was taken 3 times a day for 7 days. The only bad thing about amoxicillin is the extreme sickness it causes most people. It made me extremely nauseous even when I ate it with food and unfortunately gave me some bowel problems too. That may be because I’m 110 pounds at 5’4" and take it 3 times a day though. But from what I’ve heard, it’s a pretty worldwide experience."

7 / 10
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  • Luc...
  • Taken for less than 1 month
  • July 25, 2022

For Bacterial Infection "I have emetophobia, and I know other people browsing this site will be the same. I was prescribed this for Lyme disease (after being unable to take doxycycline due to anxiety). I am currently on day 20 of a 21-day course (!!). I am taking a very large dose, 2x 500 mg tablets, 3x a day, about twice the usual. Side effects have been mild, I already have IBS but have only had very mild and occasional stomach upset, no real diarrhea. I have experienced nausea, but again very mild, and it's been manageable/not so bad that the anxiety has spiraled - mainly felt like acid reflux to me. The Lyme rash has gone, and I don't have the symptoms I did before treatment, so I have to go on the assumption it's worked! An unpleasant 3 weeks, but I've got it done, and you can too!"

9 / 10
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3 Report
  • Ben...
  • Taken for less than 1 month
  • May 31, 2023

For Bacterial Infection "Got a bacterial infection on my right tonsil and was prescribed to take amoxicillin 500 mg, 10 tablets, 3 a day. Need to be taken until finished. In total, I had to spend from Friday to Monday to finish the medication. I got no symptoms except fatigue on Friday. On Saturday, I got nausea, stomach ache, fatigue, sore muscles, heart palpitations, anxiety attack, and trouble sleeping. On Sunday, I got all of the symptoms mentioned plus a severe headache. On Monday, the headache was gone, but the rest of the symptoms stayed, but the infection is cured. It's been two days after finishing the medication, and the remaining symptoms are still hanging around. Cool med but has hellish side effects."

7 / 10
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  • Ban...
  • Taken for less than 1 month
  • September 26, 2021

Amoxicillin for Bacterial Infection "I was on this for 3-4 days for a bacterial infection from a wisdom teeth removal (nearly 3 months after). I noticed that I was getting constipated, took something for that. Then had consistent diarrhea for 2 days, also with constant nausea. I have since stopped since it got rid of all my bacteria in my gut. Slowly getting back to normal."

1 / 10
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  • Gar...
  • Taken for less than 1 month
  • December 5, 2017

For Bacterial Infection "Day one, nauseous. Day two, vomiting. Oh my gosh, day three: diarrhea three times, horrible, and nighttime bad aches and pains. Now I've had sepsis, worst pain ever, say a 10/10. Amoxicillin 6/10 for pain, can't sleep, helps if you sit up at night, try distracting yourself by reading!"

1 / 10
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11 Report
  • Aud...
  • January 22, 2017

For Dental Abscess "I had all 4 wisdom teeth removed, plus 4 second molars (two on top and two on the bottom). Doc prescribed this antibiotic with T3. Antibiotics caused my entire body to be itchy. Each time right after taking the antibiotic, I get chills and then fever-like symptoms...dizziness, shakes, and nausea, and very disoriented. Also caused hiccups every time afterward. Goes away, but the itching doesn't. The left side of my face is more swollen than the right one. It's day two. Was told it would be much worse at day 3. Not liking this antibiotic at all. But because I had so many teeth removed at once, I have to stick with it and rinsing with salt water in order to avoid infection."

6 / 10
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9 Report
  • nic...
  • May 24, 2010

"The most common side effects of Amoxicillin include nausea, diarrhea, vomiting, rash, and itching. Among the rarer and more dangerous Amoxil side effects that might be observed are blood disorders and inflammation of the large intestine. As long as the doctor-prescribed dosage of Amoxil is followed, the chances of adverse symptoms appearing are very low. Amoxicillin is generally a very safe medication."

9 / 10
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  • Anonymous
  • Taken for less than 1 month
  • December 10, 2020

For Bacterial Infection "Today is day 7 of my 10-day round of Amoxicillin for an infected toenail. Yes, it clears up the infection. But, not without intense lingering headaches all day long, starting when I first wake up. Tylenol has very little effect on the pain. Laying in a quiet dark room helps a little bit for about an hour, then it's back to throbbing, ringing ears, and nausea. It feels like an intense migraine and tension headache combined. I am prone to yeast infections with Amoxicillin, so I took two rounds of Diflucan as well. That wasn't the issue this time."

6 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.