Clozaril Alternatives Compared
| Clozaril (clozapine) | Vraylar (cariprazine) | Caplyta (lumateperone) |
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| Clozaril (clozapine) | Vraylar (cariprazine) | Caplyta (lumateperone) |
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Prescription only
Prescribed for Schizophrenia. Clozaril may also be used for purposes not listed in this medication guide. |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar I disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Prescription only
Caplyta (lumateperone) is an atypical antipsychotic approved for adults with schizophrenia, bipolar depression (as monotherapy or with lithium/valproate), and major depressive disorder (as add-on... View more |
Related suggestions Schizophrenia
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| More about Clozaril (clozapine) | More about Vraylar (cariprazine) | More about Caplyta (lumateperone) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Clozaril has an average rating of 7.9 out of 10 from a total of 15 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 13% reported a negative effect. |
Vraylar has an average rating of 6.1 out of 10 from a total of 554 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 31% reported a negative effect. |
Caplyta has an average rating of 6.7 out of 10 from a total of 196 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 27% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Clozaril side effects |
View all Vraylar side effects |
View all Caplyta side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Clozaril prices |
View all Vraylar prices |
View all Caplyta prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other clozapine brands include: Clopine, Clozapine Synthon, Denzapine, Versacloz |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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10.3 hours |
504 hours |
18 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 956 drugs are known to interact with Clozaril:
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A total of 581 drugs are known to interact with Vraylar:
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A total of 610 drugs are known to interact with Caplyta:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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September 26, 1989 |
September 17, 2015 |
December 20, 2019 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.