Clozaril Alternatives Compared
| Clozaril (clozapine) | Vraylar (cariprazine) | Rexulti (brexpiprazole) |
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| Clozaril (clozapine) | Vraylar (cariprazine) | Rexulti (brexpiprazole) |
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Prescription only
Prescribed for Schizophrenia. Clozaril may also be used for purposes not listed in this medication guide. |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Related suggestions Schizophrenia
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| More about Clozaril (clozapine) | More about Vraylar (cariprazine) | More about Rexulti (brexpiprazole) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Clozaril has an average rating of 7.8 out of 10 from a total of 15 ratings on Drugs.com. 77% of reviewers reported a positive effect, while 15% reported a negative effect. |
Vraylar has an average rating of 6.0 out of 10 from a total of 513 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 33% reported a negative effect. |
Rexulti has an average rating of 6.6 out of 10 from a total of 478 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 26% reported a negative effect. |
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| Generic Availability | ||||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Clozaril prices |
View all Vraylar prices |
View all Rexulti prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other clozapine brands include: Clopine, Clozapine Synthon, Denzapine, Versacloz |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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10.3 hours |
504 hours |
91 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 937 drugs are known to interact with Clozaril:
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A total of 572 drugs are known to interact with Vraylar:
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A total of 592 drugs are known to interact with Rexulti:
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| First Approval Date | ||||||||||||||||||||||||||
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September 26, 1989 |
September 17, 2015 |
July 10, 2015 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.