Vraylar and Nausea: What Users Say

• Kai...
• Taken for 1 to 6 months
• August 16, 2020

For Bipolar Disorder "I was skeptical about this at first as I have tried several bipolar and antidepressant medications. I have been on Vraylar for 3 weeks now and I have never felt better in my life. I finally feel alive. At first, I had some serious nausea, but it only lasted a week and now I feel no negative side effects. If you are at the point where you think your life is over, as you no longer have a purpose and you feel as if you have completely given up, please give this a try. It has changed my life and my family's life. This was worth 10 years of suffering. I have finally found a medicine that works for me!"

• Myt...
• November 8, 2019

For Bipolar Disorder "After trying numerous meds, this finally worked for me. The only bad part is it has caused me to gain 20 lbs. I started at 155, now I'm 175. It makes me constantly hungry. Why did I rate it so high? I finally feel like the old me. I have energy, my moods are better controlled, and it controls my anxiety. The pluses outnumber the negatives. I started on the lowest dose, now I'm on 3 mg. It made me nauseous and irritable the first few days. But I noticed the difference quickly. I hope this will help someone who is looking for a new med."

• Bad...
• Taken for 1 to 6 months
• January 5, 2023

For Major Depressive Disorder "This medication caused extreme muscle weakness, urinary urgency, confusion, nausea, restless legs, insomnia, and tremors. Because of the urinary urgency and confusion, I was wrongly diagnosed and treated for a UTI, thus prolonging my time taking Vraylar. The brain fog and weakness kept me from realizing what was wrong, and it took 3 months to figure it out. The nausea and upset stomach from this medication, plus antibiotics, led to a weight loss of 20 lbs over these 3 months. Worst medication I’ve ever taken, and who knows why my psychiatrist ever prescribed it for my anxiety and mild depression! What a disaster."

• BBa...
• Taken for less than 1 month
• June 7, 2020

For Bipolar Disorder "I’ve only been on it for 3 days. I get so tired the first few hours until I try to actually go to sleep. Then I’m restless and can’t stop moving. Overheating with chills, and I feel sick the whole time I’m on it. Nausea and headaches are very bad, consistently thirsty, and body aches! I don’t know if this is normal starting out. I know that some medications make you feel sick at first, but this is unbearable."

• Wil...
• October 2, 2018

For Bipolar Disorder "After taking all the other antipsychotics, I have found Vraylar to be the most effective in controlling my symptoms. The only side effect I've had is some minor nausea the morning after my first dose. The only problem is cost, as even Medicare's co-pay is astounding! Fortunately, my new psychiatrist is able to provide me with samples."

• Wei...
• February 11, 2017

For Bipolar Disorder "I started this medication 3 days ago, and I never get side effects from medication ever. This medication messed me up. From the first day, I started getting headaches, nausea, diarrhea, and vomiting multiple times a day. I completely lost my appetite, and the weird side effect I got is hiccups. I literally get hiccups 8-10 times a day. I'm stopping this medication because it's not worth feeling like poop all day."

• Run...
• Taken for less than 1 month
• August 4, 2020

For Bipolar Disorder "I have treatment-resistant depression, and the Vraylar, so far, not so good. Super hyperactive on it. Cleaning everything. Can't sleep, but exhausted at the same time. Also, can't hold anything down, I'm so nauseated all the time! Hate it! It's been about two weeks now."

• Moo...
• October 30, 2018

For Schizophrenia "I feel like my old self! I am doing creative things like beadwork and enjoy learning again, like studying Spanish. Getting things done around the house. I have been stable on Geodon for 16 years, but was having dyskinesia. My only problem with Vraylar is the horrible insomnia. I am wondering if it will get better. A bit of nausea, but need to eat well is all. Overall, I am grateful for it. Latest review*** I have to go back to Geodon. A bit of anxiety with the Vraylar, but I wake up with a headache every day for 2 months."

• Rel...
• September 22, 2018

For Bipolar Disorder "I’ve been on Vraylar 1.5 mg for 1 month for bipolar disorder. Manic episodes, mood swings, random anger/crying were completely out of control. I started taking this in the morning, but it was making me nauseous half of the day even with a light breakfast. I switched to bedtime, and it interfered with sleep. I am now trying a lunchtime dose, which seems to be better. I have learned I cannot take it on an empty stomach (I don’t usually have that issue with medications). It suppresses my appetite. My doc added a sleep aid, and this seems to be a good combo. Once I learned the correct way to take it, it has been an amazing help to me so far. I just increased to 3 mg 2 days ago, and so far, so good. I feel like I am more alert and have more energy a lot of the time. Also, I feel the need to always keep moving, which can be tiring at times. I’ll take that over the manic and other symptoms any day! I hope it helps others the way it has me so far. The cost of this med is crazy though!"

• Sad...
• Taken for 6 months to 1 year
• April 29, 2017

For Bipolar Disorder "This medication works for me. I can get housework done, mow the grass, and just push myself to do things now. Sometimes I can't sit still. Side effects were sore muscles and nausea, which went away after a few days. Depression is gone. The only thing is it makes me a little bit nervous and on edge, so I take something else for that."

• mus...
• Taken for less than 1 month
• May 23, 2017

For Bipolar Disorder "Have had a great experience with Vraylar. Went from oversleeping on a regular basis (on Risperidone) to sleeping a healthy 8-10 hours. Feel sharper, more social, and generally in a better mood. Unfortunately, have been dealing with insomnia and on-and-off nausea. It's been two weeks since starting. Overall, the positives outweigh the negatives, and I'm hoping the side effects subside over time. Give it a shot."

• Sui...
• April 10, 2021

For Bipolar Disorder "Vraylar was, for me, quite awful. I was constantly drowsy and foggy. I would go to sleep for 12 hours, wake up for four, nap for four, and then stay awake for another four before collapsing from exhaustion. I was also pretty nauseated. I didn't see any meaningful change in my mood. What most disappoints me about my experience with Vraylar is that it was really pitched to me as a miracle drug: few side effects, quick appearance of positive effects, etc. However, it was a nightmare for me, and based on online reviews, my experience is a very common one. I have to say that it honestly really reduced my trust in my psychiatrist. (For some context, I'm bipolar II with ADHD. I've been on a lot of different things, and found that overall I respond poorly to atypical antipsychotics. I've been taking Wellbutrin for depression/anxiety, and it's really worked wonders for me. Now if only I could go to sleep before it's literally dawn, eat more than one meal a day, and actually get work done...)"

• kun...
• Taken for less than 1 month
• November 18, 2019

For Bipolar Disorder "I've been on this rollercoaster of a med for two weeks now. At first, I could have sworn I was as good as new, except for the insomnia. Come day eight or so, I was crawling out of my skin. Jerking arms, wringing feet, and nearly impossible to sleep. Worst akathisia I ever got from a med. Also, double vision, nausea, and constipation. I'm at two weeks akathisia to the point of not being able to sleep. Actually having mild hallucinations at this point. All I feel like on this med is a guinea pig."

• Ahc...
• January 16, 2017

For Bipolar Disorder "Made my depression disappear with cost. I started having chest pains during exercise and having severe hallucinations. Could not drive and felt dissociative. Felt nauseated yet starving and yet had no will to eat. Gained 3 pounds in two days taking this drug. I also had trouble urinating, and it was painful. Only took for a week before stopping at 3 mg."

• MC6...
• April 3, 2017

For Bipolar Disorder "I'm not even up to the full dose on this medication, and I feel great! Started 1.5 mg about a week ago, going up to 3 mg tomorrow. My anxiety is gone, and I haven't needed any Ativan. I'm happier and more upbeat. It's so nice to feel like myself again after two years of feeling a little off. The only thing was I experienced some nausea the first few days, but I think it's going away."

• DrB...
• July 31, 2017

For Bipolar Disorder "Most recent diagnosis is bipolar 1. I've been better since starting Trileptal about 6 months ago. Doc suggested adding Vraylar. Big mistake, as one 1.5 ml dose made me hyperglycemic, jittery, sweaty, nauseous. I fell when my muscles sort of locked up and was physically unable to speak or move for several minutes. Helpless, awful feeling. I'm not taking a second dose of this stuff."

• Sav...
• Taken for 1 to 6 months
• December 22, 2018

For Bipolar Disorder "I started Vraylar about 7 weeks ago. My doctor weaned me off of Topamax because it was affecting my cognition. I could not process logical thoughts, like the order of events in relation to time. Vraylar allowed only for 5 hours of sleep. (I already have interrupted sleep.) My doctor said to take it in the a.m. I did that today, and I feel nauseous. I’ve also gained 4 lbs. since I began. It could be “holiday weight,” though. My appetite seems to have increased. Two factors other than Vraylar could be the cause: I started running again, and that increases appetite. I’m also not eating throughout the day, which could be causing me to binge at night and eat when I wake in the night. I’m going to continue with Vraylar. It has been a good mood stabilizer replacement for Topamax. I was using samples. I first filled a prescription for it this week at a cost of $0. I have no idea why it was covered. I’ll use a coupon from the doctor if necessary."

• mik...
• Taken for 1 to 6 months
• October 18, 2016

For Bipolar Disorder "I remember eagerly waiting for this medicine to come out, and when it finally did, I think I must've been one of, if not the only patient my psychiatrist had on it. At first, while taking it in the morning, I felt super nauseated (lost weight from it actually) and felt like I didn't want to get out of bed for anything. So I started taking it at night, which helped a little, but then it suddenly became stimulating for me, so I started taking it in the morning again. That's when I started noticing the therapeutic benefit setting in, which took roughly a week to start setting in. I quit taking it a month and a half later because of akathisia, but decided to give it another go here recently and haven't really had any problems."

• Nom...
• Taken for less than 1 month
• September 11, 2024

For Bipolar Disorder "I have bipolar 1 disorder. I got diagnosed in 2019 and have had a terrible time trying to find medication that doesn't cause side effects for me without the fatigue. I was on clopixol before Vraylar, and that left me feeling very unmotivated and fatigued each morning. My psychiatrist decided to try Vraylar 7 days ago, and the difference it made in my life is fantastic. I wake up with energy and motivation for my day without the side effects of clopixol. Vraylar has me waking at 5 a.m. each morning instead of 10 a.m. each morning. I've been more motivated, energized, and clear in my thinking. I'm taking only 1.5 mg because of my sensitivity to medication. It seems to be working at that dose. I did have nausea to start with, but it went away after a few days. This is definitely the medication for me. I also take Prozac, Lamictal, and benztropine. My bipolar is now stable without all the side effects of other medications."

• Ali...
• May 11, 2017

For Bipolar Disorder "This drug was a nightmare for me. I have mood regulation disorder. I was totally anxiety ridden one minute and hiding in my closet crying the next. Tired as heck one minute, then hyper and crazy the next. I have never had mood swings this severe in my life. This medication also gave me tons of other physical symptoms, such as high blood pressure, nausea, and a general feeling of being happy and sad at the same time. I've tried a ton of meds, and this is the worst one to date. Also, it should be noted, if you're sensitive to weight gain, the trials on the drug did show 1-2 lbs gained in 3 weeks. So you might want to watch out for that."

• Mom...
• Taken for less than 1 month
• April 20, 2018

For Bipolar Disorder "For the last 25 years, all I've heard was that there is no magic pill, but just after a week, I feel like I've found it. I've had manic, depressed, mixed, agitated anxiety for longer than I can remember, trying every med on the market also. Just after an hour, I got results, CALM! I feel like I'm a different person. Did have a numbing head, hot flashes, nausea, but they have gotten better every day. I'm on 1.5 in the AM and 1.5 in the PM. I finally feel what hope is like!"

• ReL...
• Taken for less than 1 month
• November 1, 2019

For Bipolar Disorder "I was given Vraylar 3 mg (samples because I couldn't afford it even with insurance!) for my bipolar/manic episodes uncontrolled by other meds. Unfortunately, I didn't get to see if it worked because 4 days of massive migraine-type headaches and nausea (some with vomiting, sometimes w/o) I stopped for a little over a week, and the headache and nausea went away IMMEDIATELY. The doctor encouraged me to try again (1.5 mg this time). I took it for 3 days... same scenario. I read the side effects, and both are listed there, but this wasn't just slight discomfort, it was SEVERE. I asked my doc if I might be allergic. He said it was just the side effects and I should push through, but it was not going to happen. After reading ALL OVER THE internet anything Vraylar-related and speaking with a few people who have taken it, I have found only 25-30% have seen benefits from this medication. Maybe if that number was higher, I might have “pushed through,” but I'm just not seeing the point."

• Ano...
• Taken for 1 to 6 months
• June 14, 2023

For Bipolar Disorder "Been on Vraylar 1.5 mg daily for about a month and am very happy with it. This replaced Seroquel in my drug regimen. I absolutely hated Seroquel, as I felt it wasn't doing anything for me except making it extremely difficult to get out of bed every day. Anyways, I noticed a positive effect on my mood and honestly felt 'normal.' That's something I'm not used to. I'm way more chill, intrusive thoughts are less intense, and I'm motivated to move forward with my life instead of drowning in depression or blowing up my life due to mania. Side effects were mild nausea, and I ended up vomiting a couple of times in the first week or so, but it was nothing compared to the abdominal hell Seroquel put me through. I really didn't like not being able to sweat and basically overheating doing anything strenuous. This was a massive problem for me, as I exercise a lot, and summer is just getting started. Fortunately, I started sweating normally again by week 3. Great med for me!"

• Eas...
• Taken for less than 1 month
• May 5, 2016

For Bipolar Disorder "I react different than others on most meds. I took Vraylar for 4 days, it helped with my moods, but the side effects outweighed the good to it. It made me sick to my stomach, couldn't drive, had to sleep throughout the whole day, hot flashes, dehydration. It was horrible, and I couldn't handle how bad it made me feel."

• Kik...
• Taken for less than 1 month
• February 25, 2019

"Not sure what to think yet. I’ve been bounced around on various meds trying to find the right one. I was put on Vraylar for depression since none of the SSRIs have worked. I have had a lot of nausea, dizziness, and what I would consider hot flashes. I take mine in the AM. And it doesn’t seem to cause much drowsiness. I'm also taking Lamictal with the Vraylar. I’m hoping things will get better. Because I want to feel better!"