NP Thyroid and Anxiety: What Users Say

• Ama...
• Taken for less than 1 month
• November 17, 2020

For Underactive Thyroid "DO NOT TAKE THIS. I was on Nature-Throid with no problems for about a year before being switched to this garbage due to recall. I took NP Thyroid for about a week and ended up in the back of an ambulance this morning because my husband thought I was having a heart attack. I am a 30-year-old female athlete with no underlying health conditions other than an underactive thyroid. The past week on it has been a blur. Brain fog, irritability, heart palpitations, achy body and joints, breathlessness, migraines, nausea, dizziness, extreme fatigue, and anxiety. I don't know what's in this stuff, but it needs to be pulled. There is something very wrong with NP Thyroid. Stay far away from this stuff."

• Eli...
• Taken for 6 months to 1 year
• November 6, 2019

For Underactive Thyroid "Do not take this medicine! Started in July. He gave me samples first. Those were good. Did blood work again, doubled dosage and got script in August. My hair dried out and started falling out. Then insomnia, anxiety, panic attacks, depression, crying for no reason, menstrual cycle irregular, throat burning, stomach hurt, headaches, very greasy, complete brain fog, itchy with bumps, could barely talk, bad back shoulder and neck pain. Barely functioning day to day, I felt empty inside, like I was losing it. I couldn't talk right. I was waking up at 12 am wide awake, couldn't relax, completely amped and exhausted at the same time. I didn't understand what was happening. I stopped taking it. Every day my brain got clearer and felt more like me, my personality came back. I have always been healthy and didn't look at the side effects. I feel stupid for not, lesson learned. This isn't ok! I'm so glad I found this site and it all makes sense now. Please report this! I am!"

• Kas...
• Taken for 6 months to 1 year
• November 21, 2019

For Underactive Thyroid "I was on Nature-Throid for quite a long time and was doing great until it wasn't available. Then, I switched to NP Thyroid for the past year or so. The NP Thyroid has given me horrible insomnia, heart palpitations, terrible anxiety, and many more symptoms. I was so grateful to find this site and read everyone's reviews because I didn't really put it together until I started digging. I don't know what I'm going to do now for meds, but I am not staying on this any longer. The last few batches have been really bad, and I've been feeling much worse. Thank you all for writing!"

• Kin...
• Taken for 1 to 2 years
• October 10, 2019

For Hypothyroidism, After Thyroid Removal "I started on levothyroxine. It never helped, so I switched to NP Thyroid. I felt more energized and didn’t fall asleep everywhere. Recently, I started to feel tired again, falling asleep at stoplights, feeling bloated, even if I didn’t eat, feeling like I can’t catch my breath, increased anxiety, and I have this pain in the right side of my neck I’ve never had before. I noticed when I got my refill of NP Thyroid in September 2019, the color, smell, and taste were noticeably different. All these new symptoms started with this new prescription; nothing else has changed. The drug company may claim it’s still of as high a standard as before, even with their new supplier, but clearly, something is wrong if many people have the same experience I have. Let’s make this about helping your patients feel better instead of any other reason that’s been concocted; go back to the old version. I’ll be switching to something different because NP Thyroid is no longer a product worth buying."

• aka...
• Taken for less than 1 month
• May 20, 2021

For Underactive Thyroid "Last week, my pharmacy gave me NP Thyroid instead of regularly prescribed Armour Thyroid. At first, I noticed the strong smell and taste of mildew/cat wee. I checked the label on my prescription and noticed it wasn’t Armour. A week into taking this, I noticed my body aching and heart palpitations. Then my heart started pounding, and I got all jittery. My hands and knees were shaking, and I felt weak with a headache and brain fog. I called my pharmacist, and after talking to them, they exchanged that medication for my regular Armour. After looking into this medication, I found out it has been recalled multiple times, and my symptoms were identical to other multiple people's reviews. Please do not take this medicine. It is terrible."

• Sel...
• Taken for 1 to 2 years
• December 20, 2019

For Hashimoto's disease "This medication has done wonders for me, good and bad. My energy level went up, and I lost a ton of weight. I’m actually underweight now. But over the past month, my mental health has suffered greatly. I’m so depressed and anxiety-ridden. I blow up over everything and just feel utterly hopeless. It’s scary how much I don’t care about anything anymore. Is there anyone else that feels this way? I honestly don’t know if it’s my regular life stress or this medication."

• Lym...
• Taken for less than 1 month
• October 20, 2020

For Underactive Thyroid "Started taking NP Thyroid about 3 weeks ago. I was taking WP Thyroid due to recall, no longer available. I have chronic Lyme and co-infections. I've been feeling a lot better lately. About 2 weeks ago, I started feeling very anxious, heart palpitations, extreme fatigue, severely depressed, brain fog, muscle pain/aches, and the list is endless. I really thought it was one of my co-infections coming back. Paid $580 to get tested for it, and I was negative. Couldn't figure out what was causing all of this until I Googled NP Thyroid, it smells like cat pee. I will no longer be taking it. I don't know what to change it to, I see my doc on Monday, I hope to get it sorted. Please don't touch this stuff."

• Ame...
• December 4, 2018

For Hypothyroidism, After Thyroid Removal "Like most with the WP/Naturethroid shortage, was switched to this drug back in 2017. On it 4 months; 120 mg/2 grains in the am, and 30 mg/a half grain in the afternoon. Managed to get back on Naturethroid right when it became available again in early 2018, not the greatest as they reformulated it and my levels were low, but at least no side effects. When my prescription for it ran out recently, I had no insurance to see my doctor again yet, and so had no choice but to take something I already had on hand. This time, after 6 hours of taking the first dose of NP, I experienced the most profound sadness/deep depression, complete with crying spells. It lasted for hours; I was in bed crying my eyes out for no apparent reason. Not like me! And that’s not all. Headache, dizziness, anxiety, heart pounding, feeling like I was going to pass out, diarrhea, vision problems, confusion/disorientation/brain fog, no appetite, “wired but tired” feeling, shortness of breath...what a list, good grief!"

• Peg...
• Taken for 2 to 5 years
• January 15, 2020

For Underactive Thyroid "I cannot take Synthroid, so years ago, my doctor switched me to Armour, and it worked great! Then, for a year, they stopped making it. I started on what is called just Thyroid in Canada, made by Erfa. It worked beautifully. Then, after about 3 years, it went south on me. Tried Armour again, and it was not good for me anymore. I have been on NP for 3 years, and this fall, I was depressed, anxious, I’d get angry. I couldn’t figure out what happened. Never thought of it being NP until 2 weeks ago. I found out they no longer manufacture the pill in Georgia, but it is now manufactured in Europe, but no one knows where. I stopped the pill for 3 days and felt so calm and actually really good. Then, I started on a half dosage for 4 days and felt good. Today, I took a full dosage, and I feel a little weird, but not like before. My doctor wants me to see an Endo ASAP, which I will after giving this a few more days. If they change any filler, then that’s what we get the symptoms from."

• Jod...
• Taken for 6 months to 1 year
• October 15, 2018

For Underactive Thyroid "Like the majority of people, I was given NP when WP was unavailable. Cue sweats, anxiety, weight gain, and utter misery. Crying, can’t function, blurry vision. I’ve taken my first dose of NatureThroid this morning, and voila, I am a different person. I’m holding my body straight, I feel alive/awake, and I feel like I don’t have heavy, puffy eyes."

• Anonymous
• October 25, 2021

For Underactive Thyroid "I was on Armour Thyroid for many years. Pharmacy recommended NP because of the price difference, so switched me to NP, and I noticed extreme flu-like symptoms, headaches, hair loss, insomnia, swelling (even facial swelling), all-over body pain, and constant exhaustion. I asked to be switched back to Armour after a month of misery on NP, and to please make note on my account to NEVER give me NP again because of the terrible reactions. After new blood work, I unknowingly was given NP again and took it without realizing that it wasn’t Armour. My life became a living nightmare! The anxiety attacks have been awful. My nails break easily, hair falls out in alarming amounts, continuous dull headaches accompanied by brain fog that has been very concerning. The feeling of exhaustion is unbelievable, and I cannot sleep. Joint pain, miserable indigestion and reflux, profuse sweating, inflammation, and muscle aches. My energy is ZERO, and the crying makes me feel crazy! NP Thyroid is HORRIBLE!!"

• LVa...
• April 30, 2021

For Hashimoto's disease "Was switched to NP Thyroid after Nature-Throid was recalled. I was doing really well on the Nature-Throid, but I tried to stay positive in taking this one. It smells and tastes disgusting. I noticed unexplained pain in my hip, constant indigestion, upset stomach, random diarrhea. Seven months in and my T3 is off the chart, T4 and TSH are super low, basically hyperthyroid. In the past month, I developed horrible anxiety, crying randomly and uncontrollably, trouble sleeping, and fatigue. I barely recognize myself. Had a complete breakdown in the middle of an exam. My professors are mad and think I'm somehow incompetent, although I kept trying to explain I didn't know what was going on. Finally went to the doctor and found out she had prescribed Armour, but my pharmacy was filling NP instead. I'm fighting with insurance to get Armour covered, but I can't continue with NP. My temporary dose of Armour already smells better than the NP. I'm praying this works, because I don't know what I'm gonna do if it doesn't."

• Mak...
• Taken for 1 to 6 months
• January 5, 2020

For Underactive Thyroid "I was noticing symptoms of rapid weight gain (bloated face, etc.), extreme fatigue, lethargy, high sensitivity to cold, constipation, high cholesterol, etc. I was diagnosed with hypothyroidism and put on this medication (NP Thyroid) from my general practitioner. I've begun having increasing nausea, anxiety, and irritability, rapid heart rate, and haven't noticed any improvements to the original hypothyroidism symptoms. I'm going back to my doctor and requesting a change in medication."

• Amy...
• Taken for less than 1 month
• April 13, 2023

For Underactive Thyroid "I took 60 mg NP Thyroid for symptoms of fatigue related to low T3. I was jittery, and my heart rate went up to 130. I could not eat or sleep. I took it the next day and felt worse, BP went from 110/60 to 146/79. I only took it 2 days total. It has an awful taste, too. My NP took me off of it after 2 days."

• Anonymous
• August 16, 2018

For Hypothyroidism, After Thyroid Removal "I never write reviews, but want to share my experience with NP Thyroid by Acella. I have many of the same problems listed here already. I have taken thyroid replacement for 20 years. I had been on Armour for years; my dosage is closely monitored as my blood levels fluctuate a lot. My doctor switched my dosage, and the pharmacy filled it with the generic NP Thyroid instead of Armour. We have new health insurance. I decided to try it; maybe it would help keep my levels more steady. Three weeks in, and this is the worst I have ever felt mentally. I have never been so depressed in my life. I have dealt with anxiety, but this is different: hopeless, weepy, with a dark depression. I have gained over 10 pounds, and all I want to do is sleep. The confusion and brain fog are almost scary; I can't remember or figure out simple things I do every day. Maybe if I could give it more time, my body would 'adjust,' but I had to call my doctor to go back to Armour. There is no way I could take the NP another day."

• JFe...
• Taken for 1 to 6 months
• February 22, 2021

For Underactive Thyroid "Please be careful with this medication. I am barely putting it all together this morning. I was on NatureThroid for a while. I lost weight but was jittery. So my doc changed me to NP Thyroid. For 3 months, I noticed I was starting to gain weight and became extremely tired in the afternoon but thought nothing of it. Then I had my prescription refilled on 1/27, and on 1/31 everything came crashing down. I woke to my body buzzing like slight electrocution. My anxiety went through the roof, ringing in my ears (like loud buzzing), inability to focus, complete insomnia. I would wake at 12:45 every night extremely hot like a hot flash and couldn't go back to sleep (thyroid regulates body temperature). I was a zombie! I took myself off this stuff and am recovering SLOWLY because it screwed with my adrenals too. Thyroid and adrenals are linked. Awaiting blood test results to see where to go next."

• JFe...
• Taken for 1 to 6 months
• February 22, 2021

For Underactive Thyroid "Please be careful with this medication. I am barely putting it all together this morning. I was on NatureThroid for a while. I lost weight but was jittery. So my doc changed me to NP Thyroid. For 3 months, I noticed I was starting to gain weight and became extremely tired in the afternoon but thought nothing of it. Then I had my prescription refilled on 1/27, and on 1/31 everything came crashing down. I woke to my body buzzing like slight electrocution. My anxiety went through the roof, ringing in my ears (like loud buzzing), inability to focus, complete insomnia. I would wake at 12:45 every night extremely hot like a hot flash and couldn't go back to sleep (thyroid regulates body temperature). I was a zombie! I took myself off this stuff and am recovering SLOWLY because it screwed with my adrenals too. Thyroid and adrenals are linked. Awaiting blood test results to see where to go next."

• Nan...
• October 18, 2020

For Underactive Thyroid "A year ago, this month, I was suddenly finding it difficult to get NP Thyroid 30 mg. I started getting it easier through a different pharmacy. In October, I noticed a lot of little purple spots on the back of my hands. I’ve continued getting them here and there on my arms and hands. As well, I had strong heart palpitations that would sometimes make me feel faint. I had my heart checked out twice, but nothing explained the palpitations. Add to all that, I noticed my upper abdomen was feeling bloated. I was also feeling tired and anxious. Something wasn’t right. A few nights ago, something made me decide to research NP Thyroid medication, and I was shocked to see some of the side effects people were having. I quit taking it, and already, no more little purple spots! After a year of seeing them pop up here and there on my arms and hands - gone. I’m wondering if I have damaged my health taking it for a year. Don’t take this medicine!"

• Jul...
• Taken for 6 months to 1 year
• November 21, 2021

For Underactive Thyroid "I started taking NP Thyroid in April of 2021, so a little over 7 months. I have gotten married and all in this time being on the new med. I literally felt like I was dying with the amount of panic and anxiety attacks I was having, not feeling myself, brain fog, feeling doomed, exhausted, overwhelmed, and overall just off. Instead of checking on the thyroid medication, because I have taken a few different kinds since I was 11 years old when I was originally diagnosed (I’m 35 now) and never having any side effects, I completely regret it. I literally thought I was losing my mind. The waves of emotions along with the ups and downs were just brutal. I had complete loss of my sex drive along with any feelings at all. I thought that it was stress from work and my wedding, thought I had a mental breakdown. I went as far as to see a therapist and then a psychiatrist, trying multiple medications to fix this. I stopped taking the NP Thyroid and the rest a few days ago, feeling better and better every day!"

• ali...
• Taken for less than 1 month
• April 3, 2018

For Hashimoto's disease "I have Hashimoto's and hypothyroidism. I had been taking Levothyroxine for 7 years and continued to feel awful-always tired and gained weight like crazy. I recently found a new primary care physician and OBGYN who both recommended I try NP Thyroid (and selenium) given my continued and worsening symptoms while taking Levothyroxine. I think my NP Thyroid dosage was too high the first time I started taking it because I felt extreme anxiety, my heart racing, little appetite, and I would cry probably every other day for no reason. I was taking this 60 mg NP Thyroid for 6 weeks. After reporting the side effects I experienced to my doctor, she cut my dosage in half for now, and my side effects have subsided. I do have to say that despite cutting the dosage, I am feeling better than I had been while taking Levothyroxine."

• Ann...
• January 1, 2021

For Underactive Thyroid "Worst medicine I’ve ever taken. My doctor prescribed this to me, and I took it for 3 weeks. I felt weak, nauseated, had headaches, horrible anxiety, and a racing heart! I called the doctor, and she told me that she takes it and she takes a higher dose than me, so it must be something else. I didn’t listen to her, and I stopped taking it. I immediately felt better, and I changed doctors. This medicine is awful!!"

• Lor...
• Taken for 1 to 6 months
• July 22, 2022

For Underactive Thyroid "I started taking NP Thyroid in June. For the first week, I felt great, but then I started to notice some of the pills had a terrible odor, and the taste was worse. I have cats, and they smelled like cat urine, as well as my urine. Not every pill had the odor, but the ones that did, that I took, caused me terrible stomach cramps. Then, as time went on, my hair loss was terrible, constipation was 5 days, anxiety, depression, severe fatigue, it all came back as well as hot flashes. I let my doctor know, and he wanted me to have blood work before he made any changes, so after 5 weeks, I had blood work. I got it back, and my T3 was high, TSH low, and T4 was good. Before the blood work, I had blood work done, and the levels I just mentioned were all in range. I stopped it immediately. Unfortunately, my doctor is on vacation, so I can't get any meds like LDN, which worked wonders for me in the past. I am so exhausted I can barely function. I would not recommend this medication to anyone."

• EBa...
• December 29, 2020

For Underactive Thyroid "Armour Thyroid for many years with no issues. Armour became difficult to get, and a couple of years ago my doc switched me to Nature Throid. I had no issues. About a year ago, my prescription was filled with NP Thyroid. Since then, I've had horrible body aches, brain fog, depression, and bad anxiety. I literally thought I was going crazy! I've always been happy and outgoing. After many, many days of researching, I found comments and reviews that stated people on NP Thyroid feeling the same way I was. I've now been off all thyroid medication for over a month, and while tired, constipated, and other normal hypothyroid symptoms, I feel better. No longer crazy, anxious, and depressed. My body hurts some, but nothing like when taking this stuff. My doctor has now prescribed Nature Throid again, and I will start it tomorrow. I'm looking forward to getting my life back, laughing again, and being able to think and function. Stay away from NP Thyroid!!!!"

• SBe...
• Taken for 5 to 10 years
• June 16, 2020

For Underactive Thyroid "NP caused my heart to race and anxiety to happen. Never in my life did I have anxiety, so that was a real surprise. Fatigue never went away. Now that it has been recalled, I don't know what Dr. will put me on."

• JJa...
• Taken for 1 to 6 months
• May 1, 2019

For Hashimoto's disease "I was on levothyroxine for over 2 years and had constant palpitations, anxiety, and heat intolerance. Thyroid levels were WNL [within normal limits], saw a new endo who let me discontinue because my initial TSH was under 10. After 3 months of no meds, I had zero energy and all of my muscles and joints hurt. Started NP Thyroid, and I feel so much better, but I am gaining weight, about 6 lbs so far and don't seem to be plateauing."