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Ramelteon and Depression: What Users Say

Brand names: Rozerem

Depression: mentioned by 5 users (3.1%)

Based on user experiences from 161 Ramelteon reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 8.7%
dizziness 8.1%
anxiety 6.2%
nightmares 6.2%
tiredness 5.6%
headaches 5.0%
increased heart rate 4.3%
vivid dreams 4.3%
nausea 3.7%
depression 3.1%

Reviews for Ramelteon

Showing 5 reviews tagged with "depression". Clear filters to view all 161 reviews.
Commonly mentioned side effects
  • So ...
  • Taken for less than 1 month
  • March 6, 2013

Ramelteon for Insomnia "I've had insomnia to varying degrees for about 12 years now (I'm 30 and the problem started in college) and nothing ever worked reliably for more than a short amount of time. I was recently prescribed Rozerem as I'd never tried it before. Bad idea. In addition to not sleeping, I woke up feeling extremely out of sorts, fuzzy, depressed, and lethargic. Halfway through the next day I'm still struggling to focus and my thoughts are disordered at best, on top of feeling totally exhausted."

1 / 10
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89 Report
  • Bil...
  • Taken for less than 1 month
  • September 9, 2017

Ramelteon for Insomnia "Scary!!! Was only able to be on this drug for a few weeks. It gradually increased depression to such a degree that I almost admitted myself to the ER for depression watch. I've never felt depression like this. It peaked in the morning and let up by the afternoon (3-4pm). It's now the third day since I took it, and it is lifting more and more every day. Never again!"

1 / 10
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26 Report
  • Anonymous
  • Taken for 1 to 6 months
  • August 30, 2021

Ramelteon for Insomnia "I have tried Rozerem off and on for several months, and I found it to be effective at helping me fall and stay asleep. But I'm seeing a pattern of a hangover effect the next day that leaves me feeling very depressed and listless, which is not something that I have had with Ambien or benzos. So I'm probably going to stop taking Rozerem."

4 / 10
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8 Report

Frequently asked questions

  • jac...
  • Taken for less than 1 month
  • December 9, 2012

Ramelteon for Insomnia "Had horrible depression all ten days I was on Rozerem."

1 / 10
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48 Report
  • Byr...
  • Taken for 1 to 6 months
  • December 13, 2021

For Insomnia "Did nothing for sleep, just made me super depressed, and I felt suicidal, and that was a first. Don’t take this med, it is dangerous!"

1 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.