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Trulance User Reviews & Ratings (Page 5)

Trulance has an average rating of 6.1 out of 10 from a total of 278 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Trulance

Commonly mentioned side effects
  • Bet...
  • Taken for 1 to 6 months
  • September 11, 2018

For Irritable Bowel Syndrome with Constipation "Began taking for severe constipation, and from the very first to almost 3 months later, I still have nightly very, VERY watery stools for 5-8 hours. Cannot take this medicine and have any evening plans. I can almost guarantee that 1 1/2 hours after taking this medicine, I will feel the first gurgle and will spend the rest of the night in the bathroom. It has helped with the pain in my abdomen, and distension is almost gone. I feel better the next day until I take the next dose."

4 / 10
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  • Nop...
  • Taken for less than 1 month
  • November 4, 2019

For Chronic Idiopathic Constipation "I also have IBS. I have tried Trulance for about 10 days now. I have not had any diarrhea or relief other than a bit less pain in the abdomen. I have, however, had extreme ear pain, irritability, continued side pain, urination pain, dizziness, and am more lethargic than before I started the terrible drug. I did not take any today, and after being awake for 5 hours, I sat down and fell right asleep in my recliner. I am awake now but looking forward to more sleep as I finish this post. I’m seeing my doctor tomorrow to have labs done to check my liver."

1 / 10
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23 Report
  • Hou...
  • Taken for 1 to 2 years
  • February 20, 2022

For Irritable Bowel Syndrome with Constipation "I have been diagnosed with IBS-C since 2016. I tried many prescribed medications since over-the-counter meds and treatments don’t work for me at all. I’ve been using Trulance 3 mg for the last 2 years, and it has been a life-changing experience! I cut the pill in half, so I’m able to have a bowel movement in the morning and after dinner. It’s just the perfect medication ever for me. I feel much better every day and helps me to lose weight, even though I exercise 3 or 4 times a week. I give this medication a 5-star."

10 / 10
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12 Report

Frequently asked questions

  • Suz...
  • Taken for 1 to 6 months
  • March 28, 2018

For Chronic Idiopathic Constipation "I must admit I was skeptical at first to try a prescribed drug for constipation, but it works better than other over-the-counter drugs that I tried before. I empty my bowels daily now, with no effort and no extra pain!"

10 / 10
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  • mis...
  • Taken for less than 1 month
  • May 8, 2019

For Chronic Idiopathic Constipation "Took it for a week. I've been so bloated with horrible gas pain the whole time. Diarrhea all day, and then when the diarrhea is done, I strain to pass the same small pellet stool I have when I don't take anything. Tried splitting the pill in half and get the same results. Drinking 3 liters of fluids a day and still feel dehydrated. The only good thing I can say about this medication is that it was a free sample at my doctor's office."

1 / 10
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  • Bum...
  • Taken for less than 1 month
  • May 17, 2019

For Chronic Idiopathic Constipation "On Trulance, I had nothing but daily pain after three weeks' usage. No improvement at all. Even tried enemas to get things going and... nada. Also, I have been binge eating and gaining lots of weight. Going to discontinue. I hope others have more success."

1 / 10
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  • Hop...
  • Taken for 1 to 6 months
  • June 4, 2019

For Chronic Idiopathic Constipation "Have been suffering from chronic constipation for years and recently developed abdominal pain that I’ve gone so far as to have a colonoscopy to explain, but it remains unexplainable. The doctor put me on Trulance after an Amitiza attempt. It helps my pain tremendously when so far nothing else even touches it. It doesn’t, however, do much for my constipation. If it did, it’d be my miracle drug!"

7 / 10
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  • jrz...
  • Taken for less than 1 month
  • February 20, 2023

For Chronic Idiopathic Constipation "I was prescribed a particularly unpleasant drug, which I took as directed: one 3 mg pill. Shortly after ingestion, I was forced to rush to the bathroom. Three hours later, I had experienced diarrhea nine times in a row and was headed back for the tenth time. The experience was extremely uncomfortable, with cramping, bloating, and a persistent need to go. Despite being instructed to take the drug on Mondays, Wednesdays, and Fridays, I have no intention of taking it again on Friday."

4 / 10
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  • Jay...
  • July 12, 2017

For Chronic Idiopathic Constipation "After being on Linzess for 2 years, where that med caused me a range from horrible diarrhea to not working at all, so my gastro put me on this new med. It seems to work within the hour of taking it, and I do not get serious diarrhea like Linzess gave, so that's great. I am bloated, but it's too early to tell if it's from this med or not, since I've only been on it for 2 weeks. I just hope it doesn't cause me weight gain like Linzess did. One thing I do notice is that I feel tired since taking this medicine, which I don't think is just a coincidence. I'm going to try this for a month and see if that side effect goes away."

6 / 10
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  • Anonymous
  • September 14, 2017

For Chronic Idiopathic Constipation "I was so hopeful. Nothing else has worked. Took one pill. Painfully passed hard, mucus-wrapped small stool, in pain for hours afterwards, but the real surprise is I had a delayed anaphylactic reaction. Face swelled, lips swollen and painful, hives all around my mouth and sores in my mouth, throat swollen and red, trouble breathing. My face looked like it was deformed. Took Benadryl, called Trulance manufacturer, the person there did not know the drug's source, they didn't know the half-life, excretion/elimination time or way. Two days in and I am still battling the allergic reaction. If you tend to have allergic reactions, take their 'could have allergic response' seriously. Very angry."

1 / 10
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  • Har...
  • Taken for 1 to 2 years
  • June 14, 2021

For Chronic Idiopathic Constipation "It has been a long journey and not all that successful. One of the biggest problems is that the pill can take several hours to work. Once in a while, the pill does zip. My past GI doctor was not friendly and bordering on rude. I am going to a new GI doctor/practice because I need a fresh start. I follow a FODMAP diet. When I do take the pill, I feel like I am confined to my house. Something has to happen soon. I have no words of encouragement to share at this point."

2 / 10
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  • MMa...
  • Taken for less than 1 month
  • July 22, 2018

For Chronic Idiopathic Constipation "I started taking this medication 2 days ago, and within an hour of taking my first pill, I was having a bowel motion. I have taken laxatives every day for 2 years straight. I went to the GI doctor on Friday, and she gave me samples to try, and I love it so far."

10 / 10
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19 Report
  • Don...
  • February 22, 2018

For Chronic Idiopathic Constipation "I started on Trulance close to a month ago. I have chronic constipation due to massive nerve damage in the lumbo/sacral region caused by a spinal cord disease. Since taking this medication, I have actually gained 10 lbs, which I do NOT need, and I am developing sinus problems, which is what happened when I took Linzess. I was on an antibiotic every 3-4 months while taking Linzess. I have no appetite with Trulance, but I am still gaining weight? Has this happened to anyone else? I'm at a loss what to do because I'm out of options. I've taken all OTC medications and scripts, and NOTHING is working. The Trulance is a hit/miss situation, like Linzess was. Any certain things anyone has done to help with this? I'm desperate. Thank y'all."

4 / 10
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  • Cak...
  • Taken for less than 1 month
  • December 17, 2019

For Irritable Bowel Syndrome with Constipation "I have had gallstones with all of the worst symptoms like IBS and severe pain, removal of gallbladder followed by a trip to the ER. Fast forward a year of IBS with constipation and gas that I have tried to treat with a healthy diet and lifestyle. After bleeding started, I had my first colonoscopy, and they found and removed a benign polyp. Fast forward another year of avoiding dairy and upping fiber and water, still constipated with acid reflux and gas. I got to a point I couldn’t swallow food without getting choked, so I went to the doctor for the reflux and constipation again. I took Trulance for a week, thought nothing was getting better because I had hard small BM for 6 days. Day 7 - the evening after my endoscopy, it hit me. I finally had a good BM, but it was followed by hours of diarrhea. I was going every 15 minutes as if I had taken the prep drink for a colonoscopy."

5 / 10
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  • Jun...
  • October 20, 2018

For Chronic Idiopathic Constipation "I'm having a hard time with this Trulance because it's giving me stomach cramps, making my stool a little hard, also making my rectum very sore. So I'm getting very frustrated because nothing seems to work to help have a bowel movement. I only have a bowel movement about 5 times a month, and my weight is going up. I hardly can eat anything because no bowel movement. This medication is a sample for me to try out."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • July 28, 2018

For Chronic Idiopathic Constipation "I started taking this a little over a month ago. Was taking it for 2 or 3 days straight and had trips to the bathroom for long periods after. I had enough at that point because you can't live a normal life. I called the doctor, told him I'm done, and he advised me to take it every other day. He advised me that it has to work into your system and to stick with it. It does upset my stomach some for a short time after, but nothing like it was when I took it daily and do not take any dairy because that makes it worse. I've noticed that if I skip an extra day, my stomach gets more upset when I take the next dose. Does help with the issue, but I'm not sure it is a long-term answer. I still have the side pain I originally had, but it has subsided some. Hope this helps."

6 / 10
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  • LuL...
  • Taken for 1 to 2 years
  • April 3, 2023

For Chronic Idiopathic Constipation "Used Amitiza for 8 years until it stopped working. Linzess for about 2 years before it stopped working. Switched back to Amitiza at twice the dose and experienced terrible heartburn. My insurance company changed to Trulance, and I am glad they did. It has been the very best. Works well daily within 2 hours of taking it. I do occasionally have a day with no bowel movement. Usually normal, soft consistency stool. No cramping. Occasional mild diarrhea. No other side effects. I also eat fiber, take fiber supplements, and drink 3-4 quarts of water a day."

10 / 10
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8 Report
  • Tum...
  • Taken for less than 1 month
  • April 25, 2024

For Chronic Idiopathic Constipation "Was prescribed Trulance for regular episodes of constipation that I've had for years. I could not stay on this medication longer than 2 weeks. I thought that the term 'explosive diarrhea' was a gross colloquialism, but Trulance made me experience what can only be described as explosive diarrhea. The human body never ceases to amaze me with things I never thought were possible, things I really wish weren't possible. I was going to the bathroom once every twenty minutes, staying on the toilet for ten. The stomach cramps were unpleasant, but I have a high pain tolerance and deal with regular severe abdominal cramping (endo). While on Trulance, I ruined multiple pairs of underwear and felt extremely embarrassed and ashamed. I was bordering on incontinent. I gave this medication a 5/10 because Trulance certainly did its job of clearing up my bout of constipation, the problem was that it worked WAY too well. I know that I can use it as a 'last resort' for episodes of severe constipation."

5 / 10
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4 Report
  • Dor...
  • Taken for less than 1 month
  • July 14, 2023

For Chronic Idiopathic Constipation "I took Trulance for constipation but didn't find it more effective than Miralax and I got a UTI after about 4 days. After about 8 days, I started having leg cramps and soreness even while taking electrolyte rehydration pills. I stopped taking it after 12 days."

2 / 10
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  • Con...
  • Taken for less than 1 month
  • September 20, 2018

For Chronic Idiopathic Constipation "Just started off by taking half a pill, not knowing how I would react. Glad I didn't take a full tablet....lots of abdominal/bowel pain, sharp.....and hardly going so far, just a little. And took it about 3 hours ago."

3 / 10
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20 Report
  • red...
  • February 18, 2018

For Chronic Idiopathic Constipation "I have IBC, and after years of laxatives and enemas, which stopped working, I was put on Linzess for just shy of two years. I gained weight, had horrible bloat and brain fog feeling. I could not take Linzess every day, and in the last few months, Linzess raised my blood pressure. I just started Trulance for a week. I had diarrhea movements within two hours but do not feel bloat or that horrible brain fog anymore. I also stopped gaining the weight Linzess was causing. I am praying this will keep working for me."

4 / 10
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20 Report
  • Pic...
  • Taken for less than 1 month
  • July 21, 2018

For Chronic Idiopathic Constipation "Have had CIC (chronic idiopathic constipation) forever. Have had a colon bypass. This drug is not working for me. I am on day 4. Very bloated. Feel as if I need to go to the bathroom but can't. I was on Linzess for a few months. At first, it worked well, then it took longer and longer to work, and then it quit altogether. Felt awful, bloated. Quit taking. My doctor, whom I adore, suggested Trulance. Gave me a one-week sample. I won't finish. It hasn't worked since day one, and once again I feel awful and bloated. Also today, I am itching like crazy."

2 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 26, 2018

For Chronic Idiopathic Constipation "Started 2 weeks ago. Take it every night. No significant AEs except increased gas after taking. The gas actually helps reduce bloating, though, so I don't mind. Have not noticed improvement in BMs yet and feel very backed up. Wondering if I need to clean out with mag citrate before starting this drug, as I can tell I am still full of stool that isn't coming out. Will have the urge for BM and then only pass a very small amount. I will give it another few weeks and update my review if things improve. So far, not thrilled, as I was hoping this would help me :/"

2 / 10
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19 Report
  • Cat...
  • Taken for less than 1 month
  • May 7, 2018

For Chronic Idiopathic Constipation "I have chronic constipation all my life - I’m 50 years old. No pain, but I can go a week easy only having about three rabbit-sized bowel motions. On a good week, I might go 3x a hard 5-inch bowel motion. I decided to start it in a particularly bad week at night. No cramps, but lots of gurgling. Two times I went an ok BM, but at least it was back to back. The third morning was HORRIBLE. Diarrhea so bad I couldn’t control the flow, like a colonoscopy prep for hours, but dark brown like it was clearing me out all the way. I was housebound for hours. Sorry. Not for me. Back to over-the-counter laxatives, which stop working. I had high hopes."

3 / 10
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  • slo...
  • Taken for 1 to 2 years
  • July 5, 2019

For Irritable Bowel Syndrome with Constipation "I have been using Trulance on-and-off and again basis for over a year. While it definitely helps, the side effects are truly unbearable for me. I have taken it every which way...once every day, once every two days, three days, and four days. It doesn't cause diarrhea, but terrible indigestion, feeling like my insides are burning every time I eat anything...and I have a very bland diet. It also causes my hemorrhoids to flare and I am so uncomfortable. I'm currently trying to find a more natural type of treatment...maybe magnesium, or go back to Miralax which eventually works, just takes longer."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.