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Trulance User Reviews & Ratings (Page 5)

Trulance has an average rating of 6.0 out of 10 from a total of 271 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Trulance

  • Trinity
  • Taken for 1 to 6 months
  • November 18, 2018

For Irritable Bowel Syndrome with Constipation "My doctor gave me a month trial of Trulance hoping that it would work better for me. It worked within 3 0mins of taking it. I noticed a difference when I took it without food vs with food. With food, I would be running to the bathroom about 17 times before the diarrhea stopped. My rectum would be very painful afterwards. Taking Trulance without food was better, I'd go 4 times with 1 regular stool then the rest runny/explosive diarrhea. I did have side effects. I would get dizzy spells every day that I took the pill. I also started getting blurry vision, no matter how much I blinked or rubbed my eyes. The blurriness wouldn't go away. Lastly, it made me gain weight. My diet has been the same for months except my sweets have been cut down. I go to the gym for 1 hour 3 times a week. At the end of my monthly trial, I gained almost 11lbs! I have never gained that much weight that fast. Before Trulance, I was actually losing weight. I will happily go back to Linzess."

3 / 10
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  • Dcumm...
  • Taken for less than 1 month
  • May 23, 2017

For Chronic Idiopathic Constipation "The first 3 days I experienced diarrhea within 2 hours of taking Trulance 3mg tablet. I continued taking it and I am now 15 days in and have to take an enema for constipation. Seems that Trulance is no longer effective in my system. I am very disappointed!"

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27 Report
  • lisaw
  • May 9, 2019

"Had multiple bowel surgeries with resections and adhesions also have short bowel syndrome. Constantly getting intestinal blockages, in hospital and vomit stool. Linzess made me miserable! Started trulance and getting relief. I'm so thankful for it please give it about 2 weeks."

10 / 10
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21 Report

Frequently asked questions

  • rapphd
  • Taken for less than 1 month
  • August 5, 2017

For Chronic Idiopathic Constipation "I wish I could report a positive experience with this drug but I cannot. After one week I had such severe side effects that I stopped. I think this drug was pushed to market without adequate testing as I know two other people who tried this drug with horrible results. As for myself, after the week my abdomen hurt so much I cursed the day I started it. It has been three weeks and my abdomen is still so sore eating is the not even on my mind. I would not recommend this drug to anyone. It produces a modest bowel movement but the side effects far outweigh its effectiveness."

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26 Report
  • FaceH...
  • Taken for less than 1 month
  • July 17, 2017

For Chronic Idiopathic Constipation "So the first two days I was like Yes! It worked and it was normal cramp free BM. Next day a bit of diarrhea, but only two BMs like that. Well I decided to just take half of one. No cramps or pain, no BM. Skipped another day and then today I took a half. It's been two hours of off and on the toilet. I stopped having any thing solid. It's like I am going pee, but through my behind. ); don't let this sway you from trying, but stop if this happens to you."

3 / 10
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25 Report

Are you taking this medicine?

  • LuLu
  • Taken for 1 to 2 years
  • April 3, 2023

For Chronic Idiopathic Constipation "Used Amitiza for 8 years until it stopped working. Linzess for about 2 years before it stopped working. Switched back to Amitiza at twice the dose and experienced terrible heartburn. My insurance company changed to Trulance and I am glad they did. It has been the very best. Works well daily within 2 hours of taking it. I do occasionally have a day with no bowel movement. Usually normal, soft constituency stool. No cramping. Occasional mild diarrhea. No other side effects. I also eat fiber, take fiber supplement and drink 3-4 quarts of water a day."

10 / 10
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  • Bethany
  • Taken for 1 to 6 months
  • September 11, 2018

For Irritable Bowel Syndrome with Constipation "Began taking for severe constipation and from the very first to almost 3 months later, I still have nightly very VERY watery stools for 5-8 hours. Cannot take this medicine and have any evening plans. I can almost guarantee that 1 1/2 hours after taking this medicine I will feel the first gurgle and will spend the rest of the night in the bathroom. It has helped with the pain in my abdomen and distension is almost gone. I feel better the next day until I take the next dose."

4 / 10
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  • Hoppy
  • Taken for 1 to 6 months
  • June 4, 2019

For Chronic Idiopathic Constipation "Have been suffering chronic constipation for years and recently developed abdominal pain that I’ve gone so far as having a colonoscopy to explain, but remains unexplainable. Doc put me on Trulance after Amitiza attempt. It helps my pain tremendously when so far nothing else even touches it. It doesn’t, however, do much for my constipation. If it did, it’d be my miracle drug!"

7 / 10
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19 Report
  • Harri...
  • Taken for 1 to 2 years
  • June 14, 2021

For Chronic Idiopathic Constipation "It has been a long journey and not all that successful. One of the biggest problems is that the pill can take several hours to work. Once in awhile the pill does zip. My past GI doctor was not friendly and boarding on rude. I am going to a new GI doctor/practice because I need a fresh start. I follow a Fodmat diet. When I do take the pill I feel like I am confined to my house. Something has to happen soon. I have no words of encouragement to share at this point."

2 / 10
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  • Lilsue
  • Taken for 1 to 6 months
  • October 30, 2017

For Chronic Idiopathic Constipation "Been having constipation for over a year due to autonomic neuropathy, I was only going perhaps once a week or less and than it was a small amount. I was diagnosed with gastroparesis and put on that medication. The constipation continued. Went back to the Gastrologist who prescribed this medication. On morning of the 9th day (8 days of taking med) it finally kicked in, filled the pot, twice that day. However, constipation continued to point I had blockage. I have had no relief since day 9, have used for 6 weeks so far. I take the med same time each day. Its like taking nothing, again. I have started experiencing headaches, unknown if related to this particular medication or to the autonomic neuropathy. Will be returning to dr for other ideas."

2 / 10
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  • missy
  • Taken for less than 1 month
  • May 8, 2019

For Chronic Idiopathic Constipation "Took it for a week. I've been so bloated with horrible gas pain the whole time. Diarrhea all day and then when the diarrhea is done, I strain to pass the same small pellet stool I have when I don't take anything. Tried splitting the pill in half and get the same results. Drinking 3 liters of fluids a day and still feel dehydrated. The only good thing I can say about this medication is that it was a free sample at my doctors office."

1 / 10
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19 Report
  • Const...
  • Taken for less than 1 month
  • September 20, 2018

For Chronic Idiopathic Constipation "Just started off by taking half a pill, not knowing how I would react. Glad I didn't take a full tablet....lots of abdominal/bowel pain, sharp.....and hardly going so far, just a little. And took it about 3 hours ago."

3 / 10
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20 Report
  • Suzan...
  • Taken for 1 to 6 months
  • March 28, 2018

For Chronic Idiopathic Constipation "I must admit I was skeptic at first to try prescribed drug for constipation, but it works better than other over-the-counter drugs that I tried before. I empty my bowel daily now, with no effort and no extra pain!"

10 / 10
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21 Report
  • June...
  • October 20, 2018

For Chronic Idiopathic Constipation "I'm having a hard time with this trulance because it's giving me stomach cramps , making my stool a little hard , also making my rectum very sore. So I'm getting very frustrated because nothing seems to work to help have a bowel movement . I only have a bowel movement about 5 times a month and my weight is going up. I hardly can't eat anything because no bowel movement. This medication is a sample for me to try out."

1 / 10
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19 Report
  • Cake...
  • Taken for less than 1 month
  • December 17, 2019

For Irritable Bowel Syndrome with Constipation "I have had gall stones with all of the worst symptoms like IBS and severe pain, removal of gallbladder followed trip to the ER. Fast forward a year of IBS with constipation and gas that I have tried to treat with healthy diet and lifestyle, after bleeding started I had my first colonoscopy and they found & removed a benign polyp. Fast forward another year of avoiding dairy and upping fiber & water, still constipated with acid reflux and gas. I got to a point I couldn’t swallow food without getting choked so I went to doctor for the reflux and constipation again. I took Trulance a week, thought nothing was getting better because I had hard small BM for 6 days, day 7-the evening after my Endoscopy it hit me.I finally had a good BM...but it was followed by hours of diarrhea. I was going every 15 minutes as if I had taken the prep drink for a colonoscopy."

5 / 10
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  • Hous
  • Taken for 1 to 2 years
  • February 20, 2022

For Irritable Bowel Syndrome with Constipation "I have been diagnosed with IBS-C since 2016. I tried many prescribed medications since over the counter meds and treatments don’t work for me at all. I’ve been using Trulance 3mg for the last 2 years and it has been a life changing experience! I cut the pill in half so I’m able to have bowel movement in the morning and after dinner. It’s just the perfect medication ever for me. I feel much better every day and helps me to lose weight even that I exercise 3 or 4 times a week. I give this medication a 5 star."

10 / 10
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10 Report
  • Jaye...
  • July 12, 2017

For Chronic Idiopathic Constipation "After being on linzess for 2 years where that med caused me a range from horrible diarrhea to not working at all so my gastro put me on this new med. It seems to work within the hour of taking it and I do not get serious diarrhea like linzess gave so that's great. I am bloated but it's to early to tell if it's from this med or not since I only been on it for 2 weeks. I just hope it doesn't cause me weight gain like linzess did. One thing I do notice is that I feel tired since taking this medicine which I don't think is just a coincidence. I'm going to try this for a month and see if that side effect goes away."

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  • Alexa...
  • April 19, 2018

For Chronic Idiopathic Constipation "I used to have to push very hard to be able to poop. It would take me 20-30 minutes just sitting there and making a huge effort. I started developing severe abdominal pain to the point I couldn’t even walk. Several times I dropped on the floor unable to walk. I thought the pain was related to my IUD device so I removed it hoping it would help. It was on that visit that my gynecologist recommended me that if the pain didn’t go away that it was possible I had Chronic Idiopathic Constipation and that a new treatment called Trulance was available. The pain didn’t go away so I decided some over the counter laxatives but they would make me get diarrhea. So finally I changed my diet and I noticed that as long as I didn’t ate any processed foods I would be ok but as soon as I ate anything ‘unhealthy’ I would get cramps again."

10 / 10
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20 Report
  • MMano
  • Taken for less than 1 month
  • July 22, 2018

For Chronic Idiopathic Constipation "I started taking this medication 2 days ago and within an hour of taking my first pill I was having a bowel motion. I have taken laxatives everyday for 2 years straight. I went to the GI Dr on Friday and she gave me samples to try and I love it so far."

10 / 10
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19 Report
  • red...
  • February 18, 2018

For Chronic Idiopathic Constipation "I have IBC and after years of laxatives and enemas which stopped working I was put on linzess for just shy of two years. I gained weight had horrible bloat and brain fog feeling. I could not take linzess every day and in the last few month linzess raised my blood pressure. I just started Trulance for a week, I had diarrhea movements within two hours but do not feel bloat or in that horrible brain fog anymore also stopped gaining the weight linzess was causing I am praying this will keep working for me"

4 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • October 11, 2023

For Chronic Idiopathic Constipation "Trulance is an amazing drug that has been life-changing for me. I was suffering from such severe constipation that I could barely eat, had horrible abdominal cramps, and was losing too much weight. Now that I am taking this medication, I am pretty much back to normal. Some people who give the drug a bad review because it works REALLY well for constipation probably didn't need it as much as I do!"

8 / 10
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  • Donna...
  • February 22, 2018

For Chronic Idiopathic Constipation "I started on Trulance close to a month ago. I have chronic constipation due to massive nerve damage in lumbo/sacral region caused by a spinal cord disease. Since taking this medication I have actually gained 10lbs which I do NOT need, and I am developing sinus problems which is what happened when I took Linzess. I was on an antibiotic every 3-4 months while taking Linzess. I have no appetite with Trulance but I am still gaining weight? Has this happened to anyone else?? I'm at a loss what to do bc I'm out of options. I've taken all OTC medications and scripts and NOTHING is working. The Trulance is a hit/miss situation like Linzess was. Any certain things anyone has done to help with this?? I'm desperate. Thank y'all. "

4 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 26, 2018

For Chronic Idiopathic Constipation "Started 2 weeks ago. Take it every night. No significant AEs except increased gas after taking. The gas actually helps reduce bloating though, so I don't mind. Have not noticed improvement in BMs yet, and feel very backed up. Wondering if I need to clean out with mag citrate before starting this drug, as I can tell I am still full of stool that isn't coming out. Will have the urge for BM and then only pass a very small amount. I will give it another few weeks and update my review if things improve. So far not thrilled, as I was hoping this would help me :/"

2 / 10
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18 Report
  • Cat
  • Taken for less than 1 month
  • May 7, 2018

For Chronic Idiopathic Constipation "I have Chronic Constipation all my life - I’m 50years old. No Pain but I can go a week easy only having about three rabbit size bowel motions. On a good week I might go 3x a hard 5 inch bowel motion. I decided to start it in a particularly bad week, at night. No cramps but lots of gurgling. Two times I went an ok BM but at least it was back to back. Third morning was HORRIBLE. Diarrhea so bad I couldn’t control the flow like a colonoscopy prep, for hours, but dark brown like it was clearing me out all the way. I was housebound for hours. Sorry. Not for me. Back to over the counter laxatives which stop working. I had high hopes."

3 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • July 28, 2018

For Chronic Idiopathic Constipation "I started taking this a little over a month ago. Was taking it for 2 or 3 days straight and had trips to the bathroom for long periods after. I had enough at that point because you can't live a normal life. I called the dr, told him I'm done and he advised me to take it every other day. He advise me that it has to work into your system and to stick with it. It does upset my stomach some for a short time after, but nothing like it was when I took it daily and do not take any dairy because that makes it worse. I've noticed that of I skip an extra day my stomach gets more upset when I take the next dose. Does help with the issue but I'm not sure it is a long term answer. I still have the side pain I originally had but it has subsided some. Hope this helps."

6 / 10
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17 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.