Skip to main content

Trulance User Reviews & Ratings (Page 2)

Trulance has an average rating of 6.0 out of 10 from a total of 271 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Trulance

  • Darian...
  • June 21, 2017

For Chronic Idiopathic Constipation "I was diagnosed with chronic idiopathic constipation (CIC) at 19 in 2014. After trying both Amitiza and Linzess, this medicine has worked wonders that the other two had not. I could never go while on Amitiza, and I had diarrhea to a point it was just water on Linzess. Went to my gastro after having tender stomach pains and bloating and was switched to this. So far, so good. I poop on a normal consistent basis with no side effects. No more laxatives just to go to the bathroom. Thank goodness for finding something for CIC that works for me. I'd definitely recommend to others who are suffering this nasty 'disease'. Kudos"

Was this helpful?YesNo
80 Report
  • deaff...
  • Taken for 1 to 6 months
  • April 30, 2021

For Chronic Idiopathic Constipation "An absolute miracle. Don't let the negative reviews scare you. I am highly intolerable of laxatives in all forms but I found if I split the pill and take it every other day it works perfectly. No multi trips to the bathroom no pain or nausea from it. Some grumbling after 30 minutes then within two hours complete evacuation and total relief!! The pill crumples easy when split so use a pill splitter."

10 / 10
Was this helpful?YesNo
40 Report
  • SWano
  • Taken for 1 to 6 months
  • July 28, 2019

For Chronic Idiopathic Constipation "I have dealt with Chronic Idiopathic Constipation for years. Only thing that worked was Dulcolax..and that causes crazy diarrhea. I had awful stomach bloating to the point people though I was pregnant. The instant I ate, I would feel swelling , my bra got tighter, my wedding ring would cut into me...etc. I was given 4 week supply of Trulance by by dr. The results are...I no longer bloat and have stomach pain and knots. I’m not scared to eat anymore. The bowel movements are here and there. Before it was maybe once in 2 weeks. Now it’s maybe 2 in one week. I am going to keep taking this just for the comfort of eating."

8 / 10
Was this helpful?YesNo
55 Report

Frequently asked questions

  • Joliv...
  • Taken for 1 to 6 months
  • June 7, 2017

For Chronic Idiopathic Constipation "I feel 100% better! I'm having daily bowel movements & it's not just water! I'm less bloated & no stomach pains. I am still watching what I eat. I've been on Linzess before with lots of diarrhea. Now I've been on Trulance for 6 weeks! It's working WONDERFUL!!! I would highly recommend this drug! I give it a 10."

10 / 10
Was this helpful?YesNo
72 Report
  • Jo43739
  • October 14, 2017

For Chronic Idiopathic Constipation "After years of constipation and 17 days of no BM, I called my GI, and he gave me samples of this. 1 hour after I took the pill, I had a BM. I am on day 4 and have gone every day. I have to take it when I get home from work because I go to the bathroom within 15-30 minutes after I take the pill. Hope this continues to work this well. It has saved my life!! Now if I can get my insurance to pay for it, I will be happy!"

10 / 10
Was this helpful?YesNo
67 Report

Are you taking this medicine?

  • IBOuch
  • Taken for 1 to 6 months
  • May 25, 2019

For Chronic Idiopathic Constipation "I have had countless EGDs (an upper GI endoscopy), CTs, MRIs, small bowel studies, gastric emptying studies, food allergy and intolerance studies and nothing ever helped or was found to be abnormal. I've tried Linzess, Amitiza, IB guard, FD guard and now Trulance. I've also been to about 8 different GI doctors in multiple cities and even reached out to the Mayo Clinic. I've been told I can't be helped and dismissed by several doctors. Linzess caused explosive diarrhea and severe dehydration to where I was admitted and amitiza did absolutely nothing. I was prescribed Trulance which cost over $75 with insurance and after taking two pills experienced nonstop horrible cramping and pure liquid stool. I was so dehydrated I passed out at work because nothing would stay in my system. I am now stuck on a low FODMAP, gluten free, soy free, minimal sugar and soft foods just to try and maintain a semi normal life. I have to take compazine to not vomit after every meal and hyocyamine to make the cramps tolerable."

1 / 10
Was this helpful?YesNo
54 Report
  • Rose
  • Taken for less than 1 month
  • January 28, 2019

For Irritable Bowel Syndrome with Constipation "I have been suffering 45 years with severe IBS. I have taken every single prescription and over the counter medicine for it. Everything works for a couple of days and then I’m back to normal. I am now taking Trulance and it is like a miracle drug. With an hour to two after I take it I feel gurgling in my stomach and then I go diarrhea about 4 times. I feel amazing. No bloated ness anymore. I feel so empty and it feels great. Highly recommend this pill."

10 / 10
Was this helpful?YesNo
56 Report
  • Linda...
  • Taken for 1 to 6 months
  • September 5, 2017

For Chronic Idiopathic Constipation "I have been on Trulance since July 16. I have nerve damage in my stomach (gastroparesis) and rectal nerve damage from type 1 diabetes. I have a very hard time having a BM. I was on Linzess and then on amitiza. They gave me diarrhea at all times of the day. I also have fecal incontinence. Could rarely go out of the house. Trulance is like a miracle for me. I take Trulance and within an hour I start going. I go about 5-10 times in the next 1 to 2 hrs. I have a mixture of solid and diarrhea when I go. I think because there is solid with diarrhea I am able to control it until I reach the bathroom. When this process is over I can go about the rest of the day until the next pill. I am happily able to go away during these times with confidence."

7 / 10
Was this helpful?YesNo
66 Report
  • TWano
  • Taken for less than 1 month
  • July 23, 2019

For Chronic Idiopathic Constipation "I have tried everything Phillips pills, Linzess, Almatiza, tea tree root, Milk of Mag a whole year. Miralax also it worked but, bloated me and didn't empty my bowels. I have UC so fiber is out of the question. Trulance works great I don't have the diarrhea people talk about but, do go about 3-4x a day. But, not bad like having pooping on myself. You feel small cramps just go to restroom. Only reason I didn't give a 10 it does flare up hemorrhoids so have to use cream everyday. But, I do not care at this point Ill buy a case from Amazon if needed. Also have gastritis so not looking bloated/ pregnant I love it."

9 / 10
Was this helpful?YesNo
52 Report
  • Dano
  • Taken for 1 to 6 months
  • May 27, 2019

For Chronic Idiopathic Constipation "Basically, hit and miss with variable results and variable adverse events. I am taking for hard stool and occasional low (but sometimes severe) abdominal pain/distention). I am taking one pill daily on an empty stomach with H2O each morning. I have uncovered a pattern now where if I have not had a BM the day before, the next day will be explosive. Following 4 hours of diarrhea, I get migraine symptoms (courtesy of dehydration....who knows), chills and back pain. I wonder if anyone has had good luck with halving the dose or taking only a couple times a week. I would think that the manufacturer has now had enough adverse events reporting that the FDA would require a labeling change. I'm surprised there is no titration recommended based on "results". My advice before your doctor pursues a lengthy prior authorization procedure only to have you waste (pardon the pun) money on a drug you don't use is get samples first to see if you even tolerate the drug."

5 / 10
Was this helpful?YesNo
53 Report
  • Debra
  • Taken for 1 to 6 months
  • March 20, 2019

For Chronic Idiopathic Constipation "Due to surgeries, radiation and chemo damage, I'm unable to "go" on my own unless I take prune juice and sit in the bathroom for hours. It was awful and disruptive to having a normal life. When I started Trulance, it was a miracle drug for me. I started going every morning with no side effects. I felt as if I got my life back. I've been on it two months and it just stopped working. Nothing. I have to call my G.I doc and hope she has some answers. I was willing to take this drug forever even though my co-pay was $132 a month. It's close to $500 a month without insurance. Hoping for some positive answers from the doctor."

5 / 10
Was this helpful?YesNo
53 Report
  • ginge...
  • January 13, 2021

For Irritable Bowel Syndrome with Constipation "This medicine is supposed to be taken every day. With the approval from my doctor I take it twice a week. This medicine typically takes anywhere from 30 min to 2 hours to kick in. Get up at 4AM and take it with a full glass of water. I work at 9AM from home so my bowel movements are typically done then. Be prepared to be at home for 4-6 hours. Occasionally do I have abdominal pain from the medicine. Starts with some solid poo and then changes to diarrhea. I typically go diarrhea around 5-7 times that morning. My side effects on good days are just diarrhea. HOWEVER, I have a bad day at least every other week where the medicine makes me so sick and weak. It makes my chest feel really weak and my body. I typically stay somewhat dizzy throughout the day and can get headaches. Regardless of these episodes for me the medicine is still worth it, to not be living in constant horrific pain from bowel movements and constipation."

9 / 10
Was this helpful?YesNo
38 Report
  • Lin
  • December 12, 2019

For Chronic Idiopathic Constipation "I see good and bad comments. I’m going to share mine . I received samples for Trulance. I started taking this as my last resort to a total colectomy. The first few day within one hour I had bowel movements wow ! Day 5 nothing doubled over in pain . Dizziness fatigue depression Severe migraines nausea this went on for two more days had to stop when My face swelled up . This was an awful drug for me . Take with caution. Took days to get out of my system"

4 / 10
Was this helpful?YesNo
46 Report
  • luckie
  • Taken for less than 1 month
  • January 10, 2020

For Chronic Idiopathic Constipation "I have been constipated my whole life. Several months ago I started experiencing bowel blockages that ended up causing projectile vomiting, heartburn, and nausea. For years Colonics was on my list of things to do. At my last appointment, my bowels were so blocked, I drank a bottle of magnesium citrate! Wow! Wow! Wow! If your system needs cleaning out this is exactly what does. As far as the Trulance, for the 2 days, I've taken it, my belly looks 8 months pregnant from horrible bloating, gas, and ridiculous diarrhea! For safety purposes on the 1st night, I wore an overnight adult diaper on only to wake up in a huge feces mess in my bed!!! I feel horrible! Made a call to my Gastro's office today"

1 / 10
Was this helpful?YesNo
45 Report
  • Lucy
  • Taken for less than 1 month
  • August 22, 2020

For Chronic Idiopathic Constipation "I started taking Trulance after dinner and within the hour, it worked. I was so excited! I've tried so many meds in the past 20 years and none helped like this pill. I didn't have any pain n BM was not explosive like Linzess."

10 / 10
Was this helpful?YesNo
40 Report
  • Becker
  • Taken for 1 to 6 months
  • June 18, 2019

For Chronic Idiopathic Constipation "I am on my second package of this RX and it seems to work pretty well. I drink a Senna tea that I buy on Amazon. I drink the tea before I go to bed and take the Trulance in the morning. Have not had much diarrhea and between this and the tea I have been almost normal for a month now. No cramping, no gas, no pain. What has happened now is I have horrible congestion and severe tiredness. Don't want to stop taking it, but I need to see if the Trulance is causing the problem, while solving the other."

8 / 10
Was this helpful?YesNo
48 Report
  • James...
  • August 11, 2017

For Chronic Idiopathic Constipation "I was on Linzess using it only time from time as it caused severe bloating and diarrhea. I was skipping doses and was constipated then. It always required a decision should I take a pill today or not. For the last 2 months I am using Trulance and it is perfect. I am taking it in the morning and forgetting. It just works! Smooth and nice. I already forgot what diarrhea is! I feel like my life is changed"

10 / 10
Was this helpful?YesNo
59 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • January 12, 2020

For Chronic Idiopathic Constipation "I’ve been taking Trulance for about a year. I’ve had chronic constipation for the last 10 years. I’ve had multiple back surgeries but they did not completely help the nerve pain so I take anti inflammatories, and amitriptyline to help me sleep at night. The longest I’ve gone without BM was 6 days. I’ve been taking Trulance for about a year after my insurance wouldn’t cover Linzess. I don’t take it every day because I wouldn’t be able to leave my house. It takes a few hours for it to work and then 4 hours of explosive diarrhea. I have been very depressed lately and I think it is because of this medication. It’s causing stress in my life. Plus like some people said I am tired all the time. I thought it was from the pain meds but now I’m thinking it’s Trulance. I only take 1 anti inflammatory twice a day for pain and I’ve been on it for years so I don’t think that is causing the tiredness."

4 / 10
Was this helpful?YesNo
42 Report
  • Joyce...
  • Taken for less than 1 month
  • June 11, 2017

For Chronic Idiopathic Constipation "I heard about this medication from another resident at my mom's nursing home who had recently started taking Trulance , after using another medication that gave her severe diarrhea. My mom has been on Trulance 3 weeks now and the results have been excellent. For the first time in over two years she is having regular bowel movements without any ill side effects."

Was this helpful?YesNo
58 Report
  • Vicki...
  • July 3, 2017

For Chronic Idiopathic Constipation "I have always been constipated (lucky if I go once a week) for as long as I remember for different reasons. I finally addressed it with my doctor. I was referred to a gastroenterologist who prescribed Trulance. They gave me some samples while my insurance approved the prescription. I did have a bout with diarrhea after a couple weeks but it quickly subsided. After a month being on the medicine, I'm actually going 2x a day. I'm still not sure how I feel about spending more time in the bathroom but I'm not bloated anymore. I do experience more gas but better than feeling like you are about to give birth."

9 / 10
Was this helpful?YesNo
56 Report
  • beedee
  • September 24, 2019

For Chronic Idiopathic Constipation "After reading horrible things like mouth sores, hives, total loss of bowel control and more - I am the next recipient of a months worth of Trulance samples. I popped a pill with my dinner thinking it would be a couple of hours before activation. Wrong! A one hour activation period. It cleaned my gut like a mobile vacuum cleaner, but not without some side effects: I started burning in my mouth, throat and all the way down to my rectum. Every muscle I had developed through exercise ached and my legs could barely move. I felt like it had also burned off any extra fat I had on my arms, legs and around my collar bone. My face is flushed and I feel hot in my mouth. It's been a six hour ordeal and I feel like I'm coming out of it. There was quite a vile odor and a bad taste in my mouth."

5 / 10
Was this helpful?YesNo
41 Report
  • Suzie
  • Taken for less than 1 month
  • May 15, 2019

For Chronic Idiopathic Constipation "My doctor gave me a free sample of Trulance. My problem in chronic constipation I go to the bathroom daily but strain to go sometimes. Took my first dose before going to bed. Within an hour I was having stomach cramps followed by liquid diarrhea. I was awake the entire night with more of the same. I'm really shocked that my doctor gave me no insight into the possibility that people can have this kind of reaction. My constipation is mild so not sure why she thought this would help. Horrible. Just wondering when it will be safe to eat again or leave the house. When will my stomach return to normal? I will certainly ask more questions before I try any other drug cures."

1 / 10
Was this helpful?YesNo
41 Report
  • Forever...
  • October 16, 2020

For Chronic Idiopathic Constipation "I’m 45 years old and I was in total stress after this covid 19 I worked in a hospital and not time to sit on toilet all day after eating , went to Dr and gave Trulance it is working good but I just take 1/2 cuz it is very strong for me 3 mg but so far I’m feeling good I don’t have that feeling that I have to sit on toilet like an 1 hr and I take this in the morning before starting my day . It’s working good so far"

10 / 10
Was this helpful?YesNo
32 Report
  • Karen...
  • Taken for less than 1 month
  • August 16, 2017

For Chronic Idiopathic Constipation "Just switched to Trulance 3 weeks ago. First 3 days and nothing changed and then it magically started working. I was on lizness for past 14 months, but I was continuing to have such unbearable diarrhea and abdominal pain. This drug isn't perfect but pain has subsided considerably and diarrhea is almost non existent. Keeping the faith that it continues to do well."

10 / 10
Was this helpful?YesNo
50 Report
  • BBW
  • Taken for less than 1 month
  • November 1, 2019

For Chronic Idiopathic Constipation "I’m a female in my late 30’s that’s experienced severe constipation since pregnancy 6 years ago. This drug has caused nothing but dehydration, bloating, congestion and weight gain. I will not continue use of this drug."

2 / 10
Was this helpful?YesNo
37 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.