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Protonix and Heartburn: What Users Say

Heartburn: mentioned by 5 users (6.0%)

Based on user experiences from 83 Protonix reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 12.0%
nausea 8.4%
heartburn 6.0%
dizziness 4.8%
anxiety 3.6%
diarrhea 3.6%
gas 3.6%
swelling 3.6%
vomiting 3.6%

Reviews for Protonix

Commonly mentioned side effects
  • rv ...
  • April 16, 2013

For GERD "I have taken it for about 7 years now. I never had stomach problems but got what they thought was an ulcer. Later endoscopy showed no ulcer, but signs of Barrett's esophagus. I also had hoarse voice, especially in the morning. pH study pointed to GERD. Long story short, no more hoarseness. Subsequent scopes show no signs of esophagus damage. Now for the bad. Very rarely, when I eat fast, I do get choking sensations that I did not ever have before. Also, if I run out of the medicine and/or miss a dose or two, wicked bad heartburn. Never had heartburn before. As long as I stay on it, I am good."

7 / 10
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  • Bob...
  • Taken for less than 1 month
  • January 20, 2021

For GERD "My stomach really started hurting on Dec 23rd. I’ve battled reflux many times over the years. I’m 57, but not like this. I started on pantoprazole on Monday, this morning my stomach is starting to feel a bit normal. I hope so, as I’ve had this gnawing nausea, although it has gotten slightly better at times since the 23rd. Even a few occasions felt like I never had it, but it didn’t last long. I have slight other symptoms, as you all know-heartburn, indigestion, slight feeling through-but it’s the stomach that worries me. Anyone have any thoughts about stomach nausea? I’d love to hear. And does it take the meds time to fully kick in? Thank you to everyone, nothing short of GOD's blessings always."

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  • Don...
  • September 24, 2015

For GERD "I was put on this medication after my insurance company stopped covering another PPI that worked well for me. I lasted one month and spent most of it popping ranitidine since anything I ate or drank caused almost immediate heartburn. By the end of the month, I was vomiting. It was awful. I hated to be a pain, but I called my PCP and told them I needed to go back on my previous med, which, of course, involved a lot of paperwork on his part. I have a friend that swears by this medication, but mostly all I did was swear during the month I took it."

1 / 10
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47 Report

Frequently asked questions

  • tAn...
  • Taken for less than 1 month
  • December 11, 2017

For GERD "I have had acid reflux for 10 years. I've taken Nexium, it takes my reflux away. Now insurance will not pay, so now I have to take Protonix tabs 40 mg once per day. I get heartburn, heartburn so bad I have to take Tums 2 to 3 at a time. Just not happy. I must keep looking for better meds."

4 / 10
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  • Ren...
  • Taken for less than 1 month
  • September 28, 2021

For GERD "Prescribed Protonix by my doctor, and after a week and a half, I had to stop. Almost immediately, anything I ate gave me heartburn (I didn't have frequent heartburn before), headaches every morning, extreme nausea, so much that I had no appetite, foggy brain, joint pain in my hands/wrists, abdominal pain, and depression/anxiety. I wish I would have done my research and asked more questions. I'm on day 2 after stopping, and I feel slightly better. I'm going to try a cleaned-up diet and not eating so late. Let us hope it works."

1 / 10
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