Skip to main content

Caplyta and Burning: What Users Say

Burning: mentioned by 9 users (4.9%)

Based on user experiences from 184 Caplyta reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 14.1%
dry mouth 10.3%
nausea 10.3%
dizziness 9.8%
drowsiness 9.8%
tiredness 9.2%
weight gain 6.5%
burning 4.9%
hallucinations 4.3%
diarrhea 3.3%

Reviews for Caplyta

Commonly mentioned side effects
  • Cor...
  • Taken for less than 1 month
  • August 1, 2020

For Schizophrenia "I took one dosage of Caplyta and about 20 minutes in my arms and legs started to burn as if I took a niacin. Then the next day I had a searing headache. If this drug works for some, great. But not for me. I couldn't find any of my side effects on the internet."

1 / 10
Was this helpful?YesNo
88 Report
  • THa...
  • Taken for 1 to 6 months
  • December 13, 2020

For Schizophrenia "I felt burning the first day on Caplyta, and it continued the whole time. Hair loss started in about two weeks, and that was before the medicine became really intense. I couldn't stop talking, couldn't sleep, and couldn't stop moving. My throat became very sore from talking so much. I felt like I had to walk to settle my mind. I could sleep for about an hour or two a night for about the last 3 weeks on the medication. My hallucinations became terrifying to me. This was like a whole other level of my nightmare life. It was like living in an insane world. Watching TV was terrifying. I felt like I was being hunted by people at night. Urinating became painful, and I felt like I wanted to scream. There was difficulty in urinating from the pressure. I was also hallucinating more. 6 1/2 months after stopping the medication, I'm still trying to recover. It was a nightmare."

1 / 10
Was this helpful?YesNo
67 Report
  • dav...
  • Taken for 1 to 6 months
  • April 17, 2022

For Bipolar Disorder "This medicine caused problems with temperature regulation for sure and flu-like symptoms. My nose would get so stuffy I could barely breathe even after taking allergy meds. I also got a severe burning sensation in my arms and legs while feeling cold at the same time. I’d have my heat on 75 with a space heater and electric blanket and still feel cold, but my skin felt like it was being burned inside out."

3 / 10
Was this helpful?YesNo
34 Report

Frequently asked questions

  • nun...
  • Taken for less than 1 month
  • April 16, 2023

For Bipolar Disorder "I only needed to take it once, 10.5 mg, to know I'd never take it again. Within an hour, I was passed out completely and don't remember getting to the bed. Woke up after 4 hours and started having hope for it as I was feeling something shifting, more balanced, if you will. Well, then came the major headache everyone is talking about, then the burning from the inside out, unable to regulate body temperature, wobbly. Still wobbly for a couple of days, and my nose was so stuffy the next day. I really had hope. Try it for yourself but I would definitely recommend the lowest dose of 10.5 mg."

1 / 10
Was this helpful?YesNo
19 Report
  • Loz...
  • Taken for less than 1 month
  • September 26, 2022

For Bipolar Disorder "I have bipolar 2 and started this for depression. I took the first dose of Caplyta last night, about 24 hours ago now. It was terrible. About 45 minutes in, I felt my feet burning, and then the burning crept to my torso and back. It was burning so badly that I started looking for blisters! I could not rest as my skin was so inflamed. I was also freezing. I had a comforter and a blanket over me, and it’s 74 degrees in my house. By morning, I was so groggy and dizzy. The burning finally eased up by mid-morning, but even now I can still feel a bit of a burn on my arms and hands. I tell you this is a dangerous drug. I will not take another dose, and like someone else said on here, the experience has made me nervous to try other meds."

1 / 10
Was this helpful?YesNo
23 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • lex...
  • Taken for less than 1 month
  • May 20, 2022

For Bipolar Disorder "Possibly the worst I have ever felt from just one use. First, I thought I was being paranoid, but like 20 minutes after taking it, my arms felt like they were on fire. And then I threw up, and then my feet started burning, but I was freezing and instantly felt high. It was an extreme high. I then got my mom to come get me because I couldn’t walk from being dizzy and I kept falling. She took me to her house and I instantly had one of the worst headaches I have ever felt in my entire life and started throwing up. Then I checked my temp, and my fever was 100, and my heart rate wouldn’t go down and my oxygen level was 93. My feet and hands got swollen too. And I instantly started going in and out of consciousness. I ended up taking a nap, and I couldn’t stop sweating with chills, and when my bf picked me up, he said I kept passing out. I woke up this morning still sick and I went to the doctor to change my meds."

1 / 10
Was this helpful?YesNo
23 Report
  • Jde...
  • Taken for less than 1 month
  • August 12, 2022

For Bipolar Disorder "This was the worst medicine I’ve ever been on. I took it, and one hour later, my skin was burning, and I was so restless despite taking melatonin. Then, I fell asleep and woke up with a massive headache, severe dizziness, and nausea. This lasted all day. I couldn’t make food because of dizziness, and not that that mattered because I was so nauseous I had no appetite. As the day progressed, it never eased to the point where I had to go to the ER. DO NOT TAKE THIS! Try it for yourself, but I’m warning you, it’s done its damage. I’m now terrified to start new meds."

1 / 10
Was this helpful?YesNo
21 Report
  • Sar...
  • Taken for less than 1 month
  • January 7, 2023

For Bipolar Disorder "(Prescribed for bipolar II) This was the worst experience I’ve ever had with any prescription ever, and I only took one pill. In common with other antipsychotics I’ve taken in the past, it made me so lethargic I practically felt drunk. But what was so concerning I actually called the doctors after hours was that I felt unbelievably chilled to the bone (and I’m usually always hot). I was in bed freezing despite wearing four blankets, warm fuzzy socks, slippers, pants, two sweatshirts, and a beanie. Before the “drunk” feeling kicked in, I had to drive my son to work up the street, and I was blasting my heat in the car at 86 degrees! My skin began to burn badly. I can’t explain better than it being like on the verge of frostbite but was warm to the touch on the outside. My feet were and still are the worst. It’s been 8 hours since I took the meds, and I’m not too cold anymore, but my feet have felt like they’re on fire so bad I’d love to go stick them bare in the snow."

1 / 10
Was this helpful?YesNo
11 Report
  • Lal...
  • Taken for less than 1 month
  • September 18, 2022

For Bipolar Disorder "Took 1 pill (low dose to start) in the evening. I don't remember if I took it with food. 1 hour later, my hands and feet started feeling a burning sensation as if I was putting them under a hot heat lamp. No degree of cold (cold water, ice water, ice) helped with the intensity of the feeling of burning. My hands and feet were red but at a regular temperature to the touch. I was eventually able to go to sleep, and the burning sensation stopped by the next morning. With that side effect, I did not take another dose. After reading many other people's reviews, I found only one person who had a similar reaction. It must be very rare. Most reviews I read were very positive. Wish mine had been too. I also contacted the company that makes Caplyta to inform them of the side effect."

1 / 10
Was this helpful?YesNo
11 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.