Saxenda and Fatigue: What Users Say

• Nin...
• Taken for less than 1 month
• August 22, 2020

For Weight Loss (Obesity/Overweight) "On Saxenda for 5 days, still on 0.6mg dose. First day was horrible with side effect symptoms of nausea and stomach pain, but other than the first day and occasional headaches and low energy, I am fine. I am 5'7" and 190 lb, after five days I have lost 10.5 lb. I was a dieter for my life and my thyroid is underactive, hardly lose weight on a 1200-calorie diet. Now I cannot consume more than 400 calories a day."

• jaz...
• Taken for 1 to 6 months
• June 3, 2020

For Weight Loss (Obesity/Overweight) "I started Saxenda in Dec of 2018 at 230 lbs. By April of 2019, I made it down to 195. I had struggled with weight ever since I was a child. It was the first time I remember seeing my weight in the 100s! It’s 2020 now, I can’t afford Saxenda and haven’t been on it since May of 2019. I haven’t gained weight though! I’ve been between 195 and 190. Unfortunately, I struggle with weight loss so it’s been a pain, hoping to find Sax at an affordable price to go back on it. I had side effects such as fatigue and being a little grumpier but that’s about it. Sometimes I’d get nauseous but that wasn’t too bad. It does work! But it also takes work. I also ate healthier while on it and did low-impact workouts for 15 to 30 mins every few days. I just wish it were cheaper to get. :("

• Dee...
• Taken for 1 to 2 years
• July 12, 2018

For Weight Loss (Obesity/Overweight) "This is an update to a post from about 4 or 5 months back. As I said, my starting weight was 293 lb or 294 lb. In my first review, I was at 245 lb. Since then, I've lost 15 lbs (230 lb). Just remember, guys, it works SLOW. Give it a chance, stay off the scale! Take it at night to help with the fatigue, all the other symptoms will go away. Eat plenty of fruit and fiber to combat the constipation, drink plenty of water, that will help also. I promise you it will get better! Again, STAY OFF THE SCALE. Give it time, when those pants start feeling loose, then get on the scale! Lol. It's been 14 months for me now, and I am going to continue to keep taking it. Oh, and don't give yourself injections in the same spot. It will become itchy. Good luck, everybody, and STAY OFF THAT SCALE!! EAT FIBER, DRINK PLENTY OF WATER xoxo"

• Cra...
• Taken for less than 1 month
• September 19, 2019

For Weight Loss (Obesity/Overweight) "I’ve been on this for two weeks and lost 2.6kg. Currently on 1.2ml. My advice: keep your fluids up. I got super dehydrated, headache etc. I’ve been drinking mineral water which has fixed it. Also, in relation to feeling tired and sluggish, I would recommend that you need to eat quality food/smoothies. Because all my cravings and appetite have disappeared, I can’t eat rubbish because I get full, and then don’t eat anything good. Then I feel sluggish. I hope this helps some of you. Good luck with your journeys and keep going! Remember, courage is not finding the strength to go on, it’s going on when you no longer have the strength."

• Vir...
• March 17, 2021

For Weight Loss (Obesity/Overweight) "I have battled obesity/binge eating since age 11. Add to that depression, low self-esteem, and now COVID-19 lifestyle with 4 kids at home and working from home. I topped out at 263 lbs last year. Oh yeah, I left off that I have insulin resistance and PCOS. I started Saxenda right before Christmas 2020, and the nausea was pretty intense to start at 0.6mg, but thankfully no vomiting. Taking injections at night worked well for me. Fatigue was an issue in the beginning, and I can honestly say that once I truly modified my intake, my cravings faded. I do my best to stop at 1800 calories a day. I started at 3000 steps a day and am now up to 7500+ steps daily. After 3 months, I am down 38 lbs, weighing in at 225 lbs. I must admit that the injections don't do the work alone. Some days are really tough, but I have learned to stop eating at the point of satisfaction. I am excited about the next 3 months. Remember to drink your water and rest-it matters."

• DJa...
• Taken for less than 1 month
• March 1, 2021

For Weight Loss (Obesity/Overweight) "I started Saxenda 2/24/21 and so far on 3/1/21, I have lost 6.2 pounds. The only side effects that I have had are headaches and fatigue. It’s not horrible for me, and I’m able to continue. I’m still on the 0.6 dosage and look forward to losing an additional 29 pounds. Good luck to everyone ❤️"

• Jen...
• Taken for 2 to 5 years
• September 1, 2018

For Weight Loss (Obesity/Overweight) "I started taking Saxenda two years ago. I was at my wit's end. I was 37 and weighed 235 lb, which was the most I’d ever weighed. I’ve struggled with weight loss my whole life. Saxenda takes some getting used to. Make sure you titrate up to the recommended dose or you will feel very ill. Headaches, vomiting, fatigue. I am sensitive to medication side effects. I fought through that, and after about 3 months, the side effects went away as long as I took it at the same time every day. I dropped 20 lbs immediately, then it slowed. I was 207 lb for a whole year and was ready to quit, when I dropped another quick 20. I am now 160 lbs (just dropped 5 lbs last week) and, literally, none of my clothes fit me (even my 'skinny' clothes). I work out sporadically and I eat what I want, just much less of it. I don’t feel hungry anymore. I stop eating after about eating 1/2 of my food, and I feel stuffed. I never thought I’d find something that worked so effectively for me."

• Kim...
• Taken for 1 to 6 months
• April 19, 2023

For Weight Loss (Obesity/Overweight) "Started 12 weeks ago and have lost 13.2 kg (29 lbs). During the increased dosage phase, I had mild nausea for the first day or so, then very little side effects. I struggle to consume more than 1,000 calories/day while on Saxenda. As time has passed, side effects are coming to light: low Vitamin B12/low energy, general fatigue, lightheadedness, and irritation at the injection site (although that comes and goes). However, I believe these are from a significant decrease in caloric intake, not the medication itself. I have started taking a high-quality multivitamin, so hopefully that will remedy some of these issues. My weight loss each week is directly linked with how much water I take in. Low water weeks = low weight loss weeks. 3+ liters each day, and I lose at least 1 kg a week. Increasing my water intake has also helped to alleviate mild constipation and general bloat."

• Kim...
• Taken for 1 to 6 months
• April 19, 2023

For Weight Loss (Obesity/Overweight) "Started 12 weeks ago and have lost 13.2 kg (29 lbs). During the increased dosage phase, I had mild nausea for the first day or so, then very little side effects. I struggle to consume more than 1,000 calories/day while on Saxenda. As time has passed, side effects are coming to light: low Vitamin B12/low energy, general fatigue, lightheadedness, and irritation at the injection site (although that comes and goes). However, I believe these are from a significant decrease in caloric intake, not the medication itself. I have started taking a high-quality multivitamin, so hopefully that will remedy some of these issues. My weight loss each week is directly linked with how much water I take in. Low water weeks = low weight loss weeks. 3+ liters each day, and I lose at least 1 kg a week. Increasing my water intake has also helped to alleviate mild constipation and general bloat."

• Son...
• Taken for 1 to 6 months
• April 13, 2019

For Weight Loss (Obesity/Overweight) "I am 49, perimenopausal, with hypothyroidism and just recently found out I also have prediabetes. For the last 6-7 years, my weight has been increasing regardless of what I do. I was training 4 times a week and walking 5 times a week. Still, an increase to 88kg and on the rise. I was upset, so after some discussion with my endocrinologist, I started Saxenda. That was 4 weeks ago, and today I am 82.2 kg. It does suppress appetite. I am still training 4 times a week, not walking so much. It's impressive with the weight loss. The downside effects for me are fatigue and nausea, as well as a bit of constipation, but that seems to have settled a bit. I have kept myself on 0.6mgs, as I am a bit scared to up the dose, as I don't want to get any more tired. I get those 3pm droopy eyes and weariness, that seems really hard to shrug off some days. I'm losing weight, so there doesn't seem to be a reason to increase the dose when I have the required effect with less of the drug."

• Zoe...
• March 3, 2021

For Weight Loss (Obesity/Overweight) "I'm just over one week into using Saxenda, so far, I have lost 8 lbs in 7 days. You do need to control your calorie intake, but even on 0.6, my appetite disappeared. For the first time in years, I could leave food if I felt full. I have experienced a lot of fatigue, but my body isn't getting the sugar rushes and carbs that it's used to, so I will accept that as a side effect for now, my body needs time to adjust. The nausea was helped with ginger tea, but for me, it was minimal. Constipation can be helped with Movicol or Dulcolax (I needed it by day 4, but beware, as your digestive transit is slower, add another 6 hours to the time you think the laxatives should work!) You do need to drink a lot of water, which isn't a bad thing. I cannot praise this enough. For me, it's the boost I needed."

• Lan...
• Taken for less than 1 month
• March 29, 2019

For Weight Loss (Obesity/Overweight) "I started Saxenda on 3/22/19. I am 5'3", 44 years old, and my starting weight was 162.4. I work out 5-7 days per week and eat a very healthy diet. My metabolism just hasn't been working in my favor, so I reached out to my NP and got started on Saxenda. To date, I have lost 7.8 pounds in ONE WEEK!!! I do get some headaches, fatigue, and I am thirsty all the time. I had 2 days of nausea without vomiting. I find eating a rice cake with peanut butter first thing in the morning coats my stomach, and then small meals throughout the day keep the nausea away. I am very pleased with the results thus far and am looking forward to more weight shedding off. I increased my dose today to 1.2 mg. I am an RN and a huge promoter of exhausting all options first, like eating a healthy diet and exercising. Saxenda is best, in my opinion, for people who work hard to maintain a healthy lifestyle and just need a boost."

• Ell...
• Taken for less than 1 month
• September 10, 2019

For Weight Loss (Obesity/Overweight) "I have been taking Saxenda since August 14, 2019. Overall, I’m very pleased with the results. I needed to lose 80 pounds. I weighed in today for the first time since starting. I’ve lost about 20 pounds! Yay!!! My appetite has drastically reduced. I was so hungry all the time before! However, the fatigue and indigestion were pretty bad at the higher dose. My PCP said I can lower the dose. I find 1.8 works best for me, for now. I can increase later if I can tolerate it. I find small meals 4 times a day work best for me. Best of luck to all of you!"

• Can...
• Taken for 6 months to 1 year
• May 30, 2018

For Weight Loss (Obesity/Overweight) "I figured it would be time to post my review! I've been using Saxenda since December, and now it’s almost June! No big side effects except for a lot of fatigue in the first few weeks and constipation. I would highly recommend this to people who are in need of a healthy weight loss track! My starting weight was 215 pounds, and my weight now is 179 lb! I’m super happy with my results. Just remember, nothing happens overnight, and exercise is a must! Don’t listen to all the bad reviews because everyone’s body and results are different. I am so super happy I took the chance and didn’t listen to everything I read online. Take it for a few weeks and only let your decision reflect how the medicine actually affects you. Your doctor will guide you along the way, and if it’s not for you, there are so many other options out there. Good luck! I have another 21 pounds to go, but so far I am very happy with my results."

• Jen...
• October 22, 2019

For Weight Loss (Obesity/Overweight) "Just started taking Saxenda on Sunday, October 14. My start weight was 112.2 kgs (247 pounds). I weighed myself on Sunday, October 20, and the scales really shocked me, it said I was 108.4 kgs (239 pounds). I have been overweight and dieting all my life. I was recently diagnosed with PCOS. Losing weight has been very hard. I track my steps and calories, I have been reducing the size of my meals. I had half a tuna sandwich and had to stop eating. The drug works on suppressing appetite, but the side effects are also very high for me. I have had diarrhea, constipation, lack of energy, headaches, feeling sick, and vomiting. I have dry mouth and am taking Hydralyte to compensate for the lack of fluids I can keep in my system. I am in two minds about this drug, I don't know if I am going to continue it after I finish the 5 pens in my first box. The drug costs so much, $389 Australian, and can't claim anything back on my private health."

• Kat...
• Taken for less than 1 month
• July 13, 2021

For Weight Loss (Obesity/Overweight) "When I went to my physician in tears because nothing worked, and he didn't have any suggestions, I went on my own search. I came across a few promising treatments. One was Saxenda. I started taking this 3 weeks ago and have lost 17 lbs. The only side effect I have is being fatigued. If you, like me, have tried them all and nothing works, ask your doctor about Saxenda! I love it!"

• AND...
• Taken for 1 to 6 months
• October 11, 2019

For Weight Loss (Obesity/Overweight) "I started Saxenda 4 weeks ago. I lost 6 pounds in the first two days. To date, I have lost 13 pounds. The side effects are hard. I have large red bumps that get hot and itchy at the injection site, severe fatigue, headaches, and sometimes nausea. I have not been able to increase my dose higher than 1.8 because the side effects are so hard right now. Does anyone else have the red spots on the injection sites?"

• Sid...
• Taken for 1 to 6 months
• January 5, 2020

For Weight Loss (Obesity/Overweight) "Started 0.6 mg then moved to 1.2 mg 1 week later. Horrible bloating, gas, nausea, vomiting. It did take my appetite away completely, but to an unhealthy point. I lost 28 lbs in 2 months (starting weight 240 lbs, female, 36, non-diabetic, binge eating disorder, PCOS). I could only barely tolerate the 1.2 mg dose. I increased my water intake to 80-100 oz, and if I ate more than 600-800 cal during the day, I’d feel like throwing up. I had to stay on a liquid diet of smoothies and protein shakes, as solid food increased the nausea and bloating. I added a probiotic per my doctor, but no help. I tried taking the injection at night to decrease the side effects, it only made sleeping more difficult as I was up during the night with a headache and diarrhea. I experienced extreme lack of energy and shortness of breath in doing simple tasks (such as taking out garbage). My doctor and I decided to stop due to the side effects. It helped start the weight loss, but I’m not convinced it was healthy for me."

• Lot...
• May 13, 2019

For Weight Loss (Obesity/Overweight) "I started Saxenda in early February. Initially, the nausea and fatigue made me wonder if it was all worth it, but after losing 7 pounds the first week, I decided to stick it out. The best part, I have zero sugar cravings. My first month, I drank vegan smoothies and small amounts of veggies and grains because that was all I could tolerate. I lost 30 pounds in three months. Every week, when I would increase the dose per directions, I would have three to four days of horrid nausea and fatigue. I had to force myself to eat or drink anything. About 3 weeks into the treatment, I started burping like a frat boy beer-bonging. They stunk too. Painful and embarrassing. Stool softener will address the constipation, but be careful, that can turn to the opposite on a dime. I also added a probiotic to help with regulating. Now that it's been about a month or so on the full dose, I am getting used to it, and I am functioning near normal. Bottom line: This drug is like gastric surgery in a needle."

• Fif...
• August 8, 2019

For Weight Loss (Obesity/Overweight) "I am a 54-year-old female who, for most of my life, never had a weight problem until age 40. I am 5’5” and was 228 lbs. Due to prednisone, stress, and menopause, I gained a significant amount of weight. I started out on an 800-calorie high-protein diet in April 2019, supervised by my doctor. As of June 2019, I plateaued at 205 lbs for 3 weeks. My doctor suggested Saxenda. I started using it on July 10. I noticed nausea and fatigue as side effects the first two days after dosing up. Then it subsided. It’s now August 7th, and I’m down past the 200 lb mark! I dosed up to 2.4, and I couldn’t stay awake and felt very nauseous. My doctor said to go back to 1.8 and hold there. I’ve never had any issues with appetite or overeating. My issues were not eating enough and eating the right foods. One of the other reviewers mentioned that they felt sicker when they ate the wrong foods, I notice the same thing. When I eat high-protein and fiber and drink plenty of water, it eases the nausea."

• Ama...
• Taken for less than 1 month
• February 28, 2019

For Weight Loss (Obesity/Overweight) "I started using Saxenda for weight loss 7 days ago. I chose to take it at bedtime as I’d read about people experiencing nausea and diarrhea soon after taking it. My starting weight was 224.6 lbs. The first couple of days I had to remind myself to eat as food and hunger did not enter my mind. Towards the end of my first week, I noticed I was starting to feel a bit more hungry - but I am coming up to doubling my dose to 1.2 mg. Anyway, my loss after one week was 6.6 lbs. I am over the moon. Saxenda is successful for weight loss. I’ve had no negative side effects apart from a little bit of fatigue. My daily calorie intake has been approximately 1000-1200. I will attempt to give an update on a weekly basis. I am really happy so far."

• Bro...
• Taken for less than 1 month
• March 20, 2016

For Weight Loss (Obesity/Overweight) "I started on Saxenda as a last resort in late February. I'm 26, 5'6", and weighed 217 when I first started my weight loss journey. I've lost inches on my own by working out every single day and watching what I eat, but the pounds were staying the same. I've taken Phentermine, HCG shots, and so many different weight loss pills only to be disappointed and not successful. It's been almost a month since I started Saxenda, and I'm down to 196 lbs. I'm never hungry, and even though I have nausea and fatigue, I'm not complaining. I plan on staying on this until I lose my goal of 70 pounds. With my insurance alone, the medication was going to be $100, but with the coupon card on mysaxendacard.com, I got it for $30 for 5 pens!"

• Chi...
• Taken for less than 1 month
• February 23, 2019

For Weight Loss (Obesity/Overweight) "So... what is this miracle injection? Wow. I started Saxenda on Feb. 1, 2019, at a scary weight of 299.6, and in conjunction with a carb-conscious diet. As of this morning, Feb. 23, 2019, I weigh 276.8. That's 22.8 pounds lost in 3 weeks. While these results have me thrilled, I'm also a bit concerned. Is it possible to lose weight too fast on Saxenda? I feel... weird. Definitely lacking energy. It feels like a major effort to walk from one room in my house to the next. I have to remind myself to eat, and even then, usually can't finish what I've made to eat. The only other side effect I'm noticing is dry mouth, but that's easily resolved with more water. I'm at the 2.4 dose this week and do not want to stop, but I feel sluggish and 'heady,' not quite dizzy, but like I'm moving in slow motion, watching myself from a distance. I'm just scared that 'losing' this fast isn't healthy. I love the scale numbers, but in my messed up body image mind, the weight loss can't be real..."

• Chi...
• Taken for less than 1 month
• February 23, 2019

For Weight Loss (Obesity/Overweight) "So... what is this miracle injection? Wow. I started Saxenda on Feb. 1, 2019, at a scary weight of 299.6, and in conjunction with a carb-conscious diet. As of this morning, Feb. 23, 2019, I weigh 276.8. That's 22.8 pounds lost in 3 weeks. While these results have me thrilled, I'm also a bit concerned. Is it possible to lose weight too fast on Saxenda? I feel... weird. Definitely lacking energy. It feels like a major effort to walk from one room in my house to the next. I have to remind myself to eat, and even then, usually can't finish what I've made to eat. The only other side effect I'm noticing is dry mouth, but that's easily resolved with more water. I'm at the 2.4 dose this week and do not want to stop, but I feel sluggish and 'heady,' not quite dizzy, but like I'm moving in slow motion, watching myself from a distance. I'm just scared that 'losing' this fast isn't healthy. I love the scale numbers, but in my messed up body image mind, the weight loss can't be real..."

• Chr...
• April 13, 2021

For Weight Loss (Obesity/Overweight) "I have now been on Saxenda for 5 weeks and 2 days and on 3 mg for the last 9 days. Some slight nausea in the beginning and some heartburn last week, also some fatigue, but otherwise okay. In the first week, I lost 4 pounds, but in total, I have lost about 9 pounds, and during the last week, nothing at all. I am on a diet of about 1200-1300 kcal/day. I have about 30-35 pounds to lose, a 58-year-old woman with many years of yo-yo dieting. I still have the same cravings and also appetite, but I feel full very fast, so I eat less. Anyone who has experienced that weight loss increases after some time? Or am I a weak responder to the treatment?"