Skip to main content

Letrozole for Female Infertility User Reviews (Page 5)

Brand names: Femara

Letrozole has an average rating of 7.6 out of 10 from a total of 118 reviews for the off-label treatment of Female Infertility. 63% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Letrozole

  • rosita
  • Taken for 1 to 6 months
  • September 1, 2021

"I started taking 2.5 mg of letrozole but I did not ovulate, they raised the dose to 2 tablets of 2.5 mg (5 mg) and I ovulated but it did not work either .. now is the third attempt .. someone else on the same? this is very exasperating .."

6 / 10
Was this helpful?YesNo
10 Report
  • Anony...
  • Taken for less than 1 month
  • August 28, 2021

"I've been trying to get pregnant for a year naturally, no luck. Dr prescribed me with letrizole, I have taken it as instructed. I'm due to have my period in 5 days time, I just did a pregnancy test and tested negative. I'm losing hope.. has anyone experienced the same thing?"

Was this helpful?YesNo
10 Report
  • Prelly
  • May 3, 2022

"Trying to conceive almost 2 years, I don’t ovulate so was prescribed letrozole 5mg day 2-6 no ovulation. Currently trying again day 3-7 on 7.5mg I hope I get my BFP this month. Sending lots of baby dust my way and to all expectant moms"

Was this helpful?YesNo
8 Report

Frequently asked questions

  • Anon
  • Taken for less than 1 month
  • November 12, 2019

"I just started taking Letrozole for help get pregnant, I'm on 7.5 mg on Day 3 and 2.5 mg on Day 4 - I had to decrease the dose due to the side effects - I have joint, muscle and bone pain, tender breasts, fatigue and headache. It's a good thing that I am not working at this time. I am wondering whether or not to continue the course."

Was this helpful?YesNo
14 Report
  • fiz
  • April 17, 2020

"my doc prescribed me letrozole 2.5mg first month(3 to 7 days of periods ) I got my periods on 28 of my cycle next month I take again the same dose on ( 4 to 8 ) and I got my periods on 35 of my cycle not positive results"

Was this helpful?YesNo
13 Report

Are you taking this medicine?

  • Norah
  • Taken for less than 1 month
  • November 17, 2021

"Its my first time on letrozole, I am experiencing symptoms of pregnancy, took the HCG test on 11dpo, come back negative. I waited until I missed my periods, and I miss my period.Two days late and still negative test. Pray for me, I really don't want to see my periods this month"

4 / 10
Was this helpful?YesNo
9 Report
  • Anonymous
  • August 11, 2019

"I have one fallopian tube. Last year Doctor gives me letrozole tab for 3-7 days by at 9 th day start bleeding and pelvic pain. After 1 month I had ectopic pregnancy now I again trying normally to get pregnant but not success my HSG report is normal. Dr gives me gain letrozole tab tab and wondering if I should take it"

Was this helpful?YesNo
14 Report

More FAQ

  • yellow
  • Taken for 1 to 6 months
  • December 8, 2019

"I had taken one round of letrazole last month 2.5x5 days now I'm on 5mgx5 days. The side effects include swollen hands and feet along with headache and nausea. Wondering if any one has ever taken a higher dosage and if the side effects are similar."

5 / 10
Was this helpful?YesNo
13 Report
  • Red
  • Taken for 6 months to 1 year
  • January 5, 2019

"I’ve struggled with infertility for 8 years. No kids yet at all. We’ve been trying for 6. I’ve had crazy periods since I was 11 with heavy bleeding for up to 8 months at a time, had surgery, took clomid, then I got to this. Then I got to this medicine, this is my 8th month taking it. I first started out with one pill starting in day 3 of my cycle, I’m now up to 3 a day and nothing yet. "

1 / 10
Was this helpful?YesNo
15 Report
  • Alice
  • Taken for 1 to 6 months
  • July 23, 2021

"I stopped BC in October of last year, and my period never returned. I was diagnosed with PCOS (based on a telephone assessment) in January, and referred to an OBGYN who I waited 6 months to meet. In June, I was prescribed 10 days of Progesterone to force my period, followed by Letrozole 2.5mg on days 3-7 of my cycle. I had a blood test on day 22 (today), and was told I did not ovulate, so I’m being upped to 5mg for next month. Please wish me luck! I’m hopeful 5mg might work, even though 2.5mg didn’t. Your stories of success are inspiring me"

6 / 10
Was this helpful?YesNo
9 Report
  • Mrs...
  • Taken for less than 1 month
  • November 11, 2021

Femara (letrozole) "I used Femara in March 2021 after TTC for 7years, after first cycle I got pregnant. Then sadly had a miscarriage at 10 weeks. Currently on my 2nd cycle and period is due tomorrow. Will wait another week before I take a test. Good luck to all of us."

9 / 10
Was this helpful?YesNo
8 Report
  • Anonymous
  • Taken for 1 to 6 months
  • April 1, 2022

"I am suffering for PCOS my dr give me duphaston for my period to induce and stop it after having period. For my day 3 of my cycle i took letrozole 2.5mg and period come for 28 days cycle. Now I took 5mg letrozole start to my day 3 to day 7 of my cycle. and I am waiting for positive pregnancy test this month."

Was this helpful?YesNo
7 Report
  • Yummy...
  • Taken for 1 to 6 months
  • April 3, 2021

"I’ve been TTC for many years. Fell pregnant (Naturally) in 2017 but sadly miscarried due to low progesterone. 2019 I found out that I had PCOS and I was put on Metformin, Folic Acid Forte and Yaz Contraceptives for 3 months. After that I was put on Letrozole 2.5mg day 3-7. And successfully ovulated but didn’t conceive. I then upped my dose to 7.5mg this month. Fingers crossed for a rainbow baby! Baby dust to all. Xx Xx"

7 / 10
Was this helpful?YesNo
9 Report
  • Anonymous
  • July 27, 2022

"I was prescribed letrozole 5mg x 5 days on cycle day 3- 7. I began feeling ill on the 3rd day of taking the medication. I had really bad muscle/bone/ joint aches, headaches, hot flashes, abdominal pains, lack of appetite, dry mouth, cough, dizziness, nausea, and fever. I called the pharmacy to ask about side effects and was told to complete 5 day regimen since only had 1 dose left. No sinus symptoms or sore throat, but went get covid and flu tested and negative. Blood work showed elevated liver enzymes. No signs of infection. Still having headaches and now stomatitis. Every day I am feeling a little better. I read side effects can take 7-10 days to subside. I am on day 6 and still don't feel like myself. Praying I do end up pregnant after experiencing almost every side effect possible. I did have increase in follicle sizes from the medication."

3 / 10
Was this helpful?YesNo
6 Report
  • saada
  • Taken for less than 1 month
  • June 30, 2022

"Recently found out I have PCOS. My periods regular never late, then I went to my Dr. she gave me Femara just took my first pill 2-5 days of my period and I'm still hoping this month or year to get pregnant.. keep on praying.."

10 / 10
Was this helpful?YesNo
6 Report
  • Rads
  • Taken for 1 to 6 months
  • December 5, 2020

"I had 3 sessions of Femara starting from September day 3 to day 7 of each month(5 days 2.5mg per day). No luck! I was very much positive for this month as it was my last dose of taking tablets.Not sure if my gynecologist will increase the dose or will take a break and try again later."

1 / 10
Was this helpful?YesNo
9 Report
  • katty
  • Taken for 1 to 6 months
  • August 25, 2021

"“I was dignosed with PCOS since Feb 2021 and even subclinical hypothyroidism, my periods were irregular and I was not ovulating so I went to my gynaecologist . She gave me metformin and birth control pills to regulate my periods, and after 3 months on June 2021 I started letrozole 2.5 tablet from 3rd day of cycle to 7th day but unfortunately there was no pregnancy. I repeated same dose on 2nd round but no luck. Now I will start my 3rd round of letrozole with 5mg . I am hoping for the best, I pray for every lady who is trying to get pregnant they wish get fullfilled..!!”"

Was this helpful?YesNo
7 Report
  • BabyNo
  • August 4, 2021

"So I had my first baby at age 20, we got pregnant after only four days of trying, Then we started trying for baby number two only 8 weeks after my sons birth, I got a full test done and I was diagnosed with PCOS, we kept trying but nothing for a year and a half. Finally got pregnant but miscarried at 12 weeks got pregnant again a year later only lasted to Five weeks, started metformin for two years before starting Clomid for three months and nothing I did not ovulate. I’ve stopped ovulating and don’t have regular periods at all! Last pregnancy was seven years ago my son is now Ten. So I’ve started Femolet I’m on my first month now 2-6 days of my period and doctors say best chance getting pregnant is on the 14 day of the cycle... also on medication that helped me have a period with in a week... I’m praying this works as we can not afford IVF... everyone’s stories give me so much hope ♥️"

7 / 10
Was this helpful?YesNo
7 Report
  • NotLi...
  • Taken for less than 1 month
  • December 1, 2020

"I first went on Clomid after 3 years of not conceiving while dealing with PCOS and imbalances in hormones. But Clomid worked! Now on Letrozol for *hopefully* baby #2 but having bad preAF symptoms. Not feeling good about this one- even though xray showed follicle ready to pop on Day 12. Hubs S is healthy and fine. We did the do when we were supposed to. Just wishing I were prescribed Clomid instead."

2 / 10
Was this helpful?YesNo
8 Report
  • Babyd...
  • Taken for 1 to 6 months
  • January 12, 2022

"I have PCOS & was put on Medroxyproges for 10 days to force my period, and instructed to take Letrozole 2.5mg from days 3-7 of my cycle. I had a blood test on day 22 which showed it didn’t work. Same process was repeated and my dose was increased to 5 mg, didn’t work. Same process but I was given 7.5 mg and it didn’t work. However, the next month (still at 7.5mg) my hormone level was at a 7 in my bloodwork. My doctor said it needs to be at least 20 to ovulate, but up until then, my number was always less than 1, so for it to be 7 was a good jump! My period actually came naturally, and that month at the same dose I OVULATED. I didn’t get pregnant but that was fine - I was so excited to have ovulated. My period came naturally again & I took the same dose but didn’t ovulate! My number was less than 1 again. Am I ovulating after the blood test? Has this happened to anyone else?"

6 / 10
Was this helpful?YesNo
5 Report
  • Beti
  • Taken for 1 to 6 months
  • August 26, 2021

"Hi, I’ve been TTC since 2018. I’m 39 now. Have unexplained infertility. Had 2 rounds of short protocol. 2 follicles each time but no eggs. My doctor then tried natural modified with letrozole 2.5mg for 5 days. At first scan on day 8 nice lining and 2 follicles. Went back for another scan 3 days later, follicles had shrunk and lining had thinned. No period , so did 2 tests both negative. When I was 12 days late had another internal scan which showed thick lining. Just waiting for period so I can start letrozole 5mg. Anyone else experienced something like this?"

Was this helpful?YesNo
5 Report
  • Ash
  • Taken for 1 to 6 months
  • April 23, 2022

"I was diagnosed PCOS in June 2021. Started with glucophage 500mg B.D. after 4 months I was prescribed letrozole 2.5mg day 2-5 with HCG shot on day 13 after ultrasound confirmed mature follicle of 1.9cm. The treatment failed the first time. 2nd cycle dose was increased to 5mg followed by HCG shot on day 13 but still didn't get pregnant. On 3rd cycle dose increased to 7.5mg with HCG shot on day 13 but still no pregnancy. I even took duphaston later in the cycle to help with progesterone levels. I fail to understand why it didn't work."

1 / 10
Was this helpful?YesNo
4 Report
  • Len
  • Taken for 1 to 6 months
  • October 14, 2021

"I am suffering from infertility. Now taking my 5th cycle 5mg with letrozole accord but still struggling. I get so stressed and depressed over this. Me and my husband did it every other day during my previous cycle but still nothing happened"

5 / 10
Was this helpful?YesNo
4 Report
  • tweet...
  • Taken for 1 to 6 months
  • September 20, 2021

"I have been taking letrozole since Sep 2020, took it for more than 5 cycles, it helped me ovulate but could not conceive. Did laparoscopy and my tubes were found to be blocked. Dr managed to successfully unblock waiting to take letrozole this month, I hope all will be well."

9 / 10
Was this helpful?YesNo
4 Report
  • Anonymous
  • Taken for less than 1 month
  • April 26, 2021

"I started searching for side effects for letrozole and came across this site. I have been trying to get pregnant for 3 months, first on Clomid and now on Letrozole. 2.5mg for 5 days. The side effects are horrendous and scary. I am not spotting, I am practically bleeding as though I have my period and the joint pain is off the charts. This is my 3rd day. After reading all the wonderful comments here I took the 4th pill and will take the last one tomorrow. I am still a bit skeptical about what exactly is causing this amount of bleeding and honestly scared. It’s the weekend otherwise I would have called my doctor. Does anyone else have these side effects? Wishing you all lots of luck and baby dust! :)"

Was this helpful?YesNo
4 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Female Infertility

Care guides

Symptoms and treatments