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Letrozole for Female Infertility User Reviews (Page 4)

Brand names: Femara

Letrozole has an average rating of 7.6 out of 10 from a total of 118 reviews for the off-label treatment of Female Infertility. 63% of reviewers reported a positive experience, while 13% reported a negative experience.

Reviews for Letrozole

  • Anony...
  • Taken for 1 to 6 months
  • March 30, 2023

"I have PCOS and was prescribed this medication. I took a dose of 2.5mg for 5 days and the first cycle didn't work. The doctor increased the dose and I took it for 8 days, it gave the right size of egg. He did the HCG shot but no results for 5 cycles. So so low, but trying the 6th cycle now. Please pray for me that it works."

4 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • February 15, 2022

"I have suffered with PCOS for years and have never been pregnant before. Me and my partner have had unprotected sex for astound 5 years. He has low sperm morphology. We were told to have IVF/ICSI straight away, but then a different fertility nurse told me to try letrozole just in case. I was certain it wouldn’t work. I was prescribed 2.5mg days 2-6. The first month it didn’t work, despite us having timed sex and having ovulation confirmed by ultra sound. No trigger shot or blood tests. On the second month (this month!), it worked! I still can’t believe it. Had blazing positive tests on 10dpo. One thing I would say is that on both months, my boobs were VERY sore, so maybe this is a side effect of letrozole instead of pregnancy. I also had mild headaches on both rounds. Aside from this, letrozole has been absolutely fine and I haven’t had any serious side effects, I’d of happily continued taking it if I didn’t get pregnant. Don’t lose hope!!! 10/10 from me."

10 / 10
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  • MCano
  • Taken for 1 to 6 months
  • December 17, 2020

"I had a miscarriage at 8 weeks in October. In November, I started taking 2.5 mg Letrozole day 2-6, no clear sign for O. Now on my second month, took Letrozole day 3-7, had O on cycle day 11. Fingers-crossed! Baby dust wishes to all of you."

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Frequently asked questions

  • Anonymous
  • April 8, 2021

"I had an ectopic pregnancy 8 months ago and was told to wait 6 months before trying again so after 6 cycles on my 7th cycle of trying again my follicles didn't mature and I didn't fall pregnant this month my doctor put me on 5mg letrozole from days 2 to 6 I had a follicle measuring 17mm on cd 15 but didn't fall pregnant. This cycle I was put on 7.5 mg letrozole so fingers crossed it works this time!!"

5 / 10
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  • Hopef...
  • Taken for 1 to 6 months
  • June 8, 2021

"So far 6 months on letrezole with no success :( trying to concieve I have PCOS and am pushing 35... We've been trying for two years now. Started 6 months ago on 2.5mg of letrezole, and after two cycles, went up to 5mg. Have an appointment to see about possibly increasing dose of changing medications. Anyone else take this long in letrezole to get pregnant?"

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Are you taking this medicine?

  • Anon
  • Taken for 6 months to 1 year
  • May 1, 2021

"I was put on letrazole by my fertility specialist as I wasn’t ovulating. I ovulated while on it every month, but didn’t fall pregnant until the 8th month. The only issues between me and my husband were that I wasn’t able to ovulate on my own. So be patient it may just work for you too!"

10 / 10
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  • Flossy
  • January 6, 2020

"I started at 5mg letrozole to take days 3-7 of my cycle. My cycles were really long (50-65 days). Did 5 cycles at 5mg and no pregnancy. Dr said I was ovulating too late in my cycle and this was the problem, but ordered the HSG, all the tests. She also upped my letrozole dose to 7.5mg days 3-7 of my cycle. I get bloodwork to check my progesterone (to ensure I’ve ovulated) on CD24, call the clinic the next day for the results and I have ovulated every cycle, between days 16-19) PLUS I have normal length cycles 26-29 days after starting the 7.5mg letrozole! All my other tests were normal, husbands tests normal. This will be my fourth cycle on the 7.5mg dose- fingers crossed! It does work though, inducing ovulation AND regulating cycles! The only side effects I’ve had, one actually just came on about 2-3 weeks ago (?) and that was the severe joint pain- both knees and both hips. My cramps have also been worse during my period- but that’s been the entire time I’ve been taking it."

8 / 10
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More FAQ

  • Ray
  • April 3, 2021

"I have been trying to conceive for two years now, last month my Doc placed me on letrazole 2.5mg, just started mine though today makes it day 6 ending tomorrow for my first cycle. Been having terrible headache since morning, I guess that's one of the effect . I hope and pray I test positive this month. Baby dust to you all"

8 / 10
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  • Noma
  • Taken for less than 1 month
  • August 15, 2023

"I was diagnosed with PCOS in May 2023, and I was put on Yaz for 3 months. Then my ob/gyn induced my ovulation with Letrozole Laradex CD5 on a 5mg dose. I am hopeful that I will get pregnant. Sending hopeful dust to all the PCOS warriors. Let's soldier on."

9 / 10
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  • Ebby
  • Taken for 1 to 6 months
  • February 18, 2022

"I was diagnosed with PCOS a few years ago and after trying to conceive for 6 months with no luck, my doctor prescribed letrozole. I took 2 rounds, the first was 2.5mg and I did not ovulate due to an ovarian cyst. My second round was 5mg and I had two mature follicles on my sonogram. I did ovulate and then found out I was pregnant. I did not have any side effects and would highly recommend it."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • August 28, 2021

"Success! I took 2.5mg 1x a day letrozole first round did not get pregnant. Second month 2.5mg 2x a day got pregnant!!! Now my son is 2 years old. Now I am trying baby #2 I did again 2.5mg first cycle did not work. Now I am starting 5mg hopefully I get my BFP!!"

10 / 10
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  • MCano
  • Taken for 1 to 6 months
  • February 22, 2021

"Took 5mg letrozole day 2 to 6. Got pregnant cycle 4 but pregnancy stopped at 6 weeks but no signs... so only found at I was miscarrying at 12 weeks (first scan)... :( Started again. 5mg. My second cycle totally failed as my follicules did not grow beyond 13mm. Will start cycle 3 next month with Letrozole increased to 7.5mg. Good luck to everyone!"

9 / 10
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  • UTano
  • February 20, 2021

"I’ve had first dose (5mg) of Letrozole from days 3-7 ,no dominant follicles so doctor recommends I return next month for another dose. I am encouraged by the positive reviews. I pray that it works second cycle"

6 / 10
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  • Lulu
  • Taken for 6 months to 1 year
  • December 4, 2020

"Went to a fertility doctor.. They put me on Letrozole... The first 3 months... I ovulated but didn't become pregnant so they gave me another 3 months!! - that didn't work either.. so they decided my partner and I need to try Intrauterine Insemination (IUI), which I was excited about but to get public funding I had to lose weight. So while I lost the weight I was given another 3 months of letrozole(which didn't work either) I'm close to losing all the weight I need to so I asked for another 1 month to carry on trying while losing the weight. So after 10 months on Letrozole I'm hoping I can either get pregnant this last round or lose this weight to get the IUI!!"

2 / 10
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  • Anna
  • Taken for 1 to 6 months
  • January 7, 2020

"I took 2.5 mg Femara last month and went to check my ovulation rate. It shows my progesterone level was very low and seems like I didn’t ovulate at all. My doctor has increased dose 2.5 to 5 mg. Not sure whether it will work or not. Hoping for the best!"

1 / 10
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  • Arshiya
  • Taken for less than 1 month
  • October 29, 2021

"I am suffering from PCOS its been 4 years for my marriage last month I had taken letrozole 2.5mg but it didn't work and ovulation was very slow. I got very depressed about that and now I am on 2nd cycle doctor has prescribed letrozole 5mg. I had ovulation on time waiting for the 10dpo to take test I am very much scared I don't know what it will come. Please ladies pray for me to get pregnant"

7 / 10
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  • KTano
  • Taken for less than 1 month
  • April 19, 2018

"I took two 2.5 mg pills, at night, for cycle days 3-7. I had no side effects the first 3 days. Then the 4th day my right knee started hurting when going up and down stairs. It hurts every once in a while so I thought it was no big deal. Well now it is unbearable. I cannot hardly move my knee without pain. It hurts to drive, cross my legs, walk, etc. I have been off this pill for 2 full days and it is getting worse, not better. Then this morning I had a severe headache. Quite possibly the worst one I have ever had. It took all I could do to get out of bed. I also had severe joint pain in my shoulders. I have never had that. I am praying that the pain subsides or I may not be able to drive/work. Only benefit is that my insurance company (anthem) covered this pill 100% because it is labelled as breast cancer preventative. This is nice as fertility drugs are not typically covered."

4 / 10
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  • Eli
  • Taken for 1 to 6 months
  • July 28, 2021

"I tried to conceive for a year and took letrozole 2.5 mg for 3 cycles as recommended by my doctor as a treatment for unexplained infertility. After the 3rd cycle, I got pregnant. I was soo excited but unfortunately, at week 5 and 3 days I felt intense cramps and started bleeding. I went to the ER and turns out that I had an ectopic pregnancy that had ruptured and was filling my uterus with blood and had to have an emergency surgery. They had to remove my left fallopian tube because that’s where the embryo was. The doctor said that letrozole increases the risks of ectopic pregnancies, which I didn’t know previously. Please be very careful when trying letrozole and have proper medical supervision. Good luck everyone"

1 / 10
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  • Hopeful
  • Taken for less than 1 month
  • February 8, 2022

"I just started my first cycle of letrozole. Reading all these reviews and everyone is giving me so much hope. I really needed this. I hope that it works out for me. I am happy for everyone who has been successful."

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  • Norah
  • Taken for less than 1 month
  • November 17, 2021

"Its my first time on letrozole, Iam expriencing symptoms of pregnancy, took the hcg test on 11dpo, come back negative.i waited until i missed my periods, and i miss my period.Two days late and still negative test. Pray for me, i realy dont want to see my periods this month"

4 / 10
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  • DKC
  • March 3, 2023

"So at 40, I ended up pregnant after my husband had a vasectomy! Yes we tested it, and it was clean...then 8 months later I find out I'm 3 months pregnant! Thinking I was just missing periods due to age...Yes, he is fertile again! We have our miracle baby boy now! So we decided to try again for another since we completely started over with the kids. This time I've had three Chem pregnancies in 7 months! I am 42 now and can obviously get pregnant. The doctor put me on letrozole 2.5 on days 3-7 to help move things along. Now just moved to 5mg days 3-7 but I will warn you..... it gives me horrible headaches! Also just feel sick and have anxiety due to the symptoms it gives me. The worst is days 3-5 on the medication. Praying for a pregnancy to stick! Also taking progesterone post-ovulation now to help. Baby dust to all!"

6 / 10
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  • SHAQU...
  • Taken for 6 months to 1 year
  • March 14, 2020

"I’ve been taking Letrozole since August or September last year to help me get pregant. I’ve been on the clear blue ovulating kits I got the smile face January 10th I had intercourse soon as I got the smily face I took pregnancy tests a month later still no positive pregnancy test. Hopefully this time works we been trying 6 in a half years!.."

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  • Anonymous
  • Taken for less than 1 month
  • February 24, 2020

"I recently found out I have PCOS. My periods went from regular to none, back to regular then I started my period twice in one month and didn't stop bleeding HEAVY for 3 months. I was put on provera for a year, 21 days a month to help regulate my period. Well, I've been trying to get pregnant for 2 years after my miscarriage. My doctor recently started me on Femara. I just took my first pill but I'm confused because my periods are light so idk if that will affect anything. Hopefully I ovulate and my period isn't prolonged!"

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  • Ppp
  • Taken for 1 to 6 months
  • March 20, 2022

"I'ma pcod patient and I have had iui/ivf twice in 2016/17, but no luck. In 2020 conceived spontaneously resulted in missed abortion in 1st trimester. Again tried for conception after one year with letrozole 2.5 mg I got pregnant on 1st try but lost my baby within one week of birth. Again trying with it but no luck. I'm on 3 rd cycle of letrozole 2.5mg"

10 / 10
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  • Bear
  • Taken for 1 to 6 months
  • January 3, 2024

"Got pregnant with my first on cycle 3. Tried for a second baby for 7 cycles. I have regular cycles and ovulate. Started taking Letrozole cycle day 3-7, 5mg on cycle 8 of trying. No luck on pregnancy, though I did see my estrogen levels decrease and FSH increase, so it was doing what it was intended to do. The same thing happened on cycle 9 and 10. On cycle 11, I increased to 5mg/day for cycle day 3-7. No luck. Going to try one more cycle, pray for me, and send good vibes for a pregnancy. I am happy for those of you that this worked. I am rating it as effective as it did, in fact, lower my estrogen and increase FSH which was the goal."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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