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Letrozole for Female Infertility User Reviews

Brand names: Femara

Letrozole has an average rating of 7.6 out of 10 from a total of 118 reviews for the off-label treatment of Female Infertility. 63% of reviewers reported a positive experience, while 13% reported a negative experience.

Letrozole rating summary

7.6/10 average rating

118 ratings from 177 user reviews.

Compare all 64 medications used in the treatment of Female Infertility.

10
47%
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12%
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3%
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5%
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9%
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1%
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Reviews for Letrozole

  • Lucky...
  • August 31, 2020

"I have been trying to get pregnant for about 1 year with no luck. Even tried Clomid but it didn't work. My doctor prescribed letrozole day 2-6. I was lucky I got pregnant the same month. I am now 3 months pregnant. I also tested positive a week prior to my expected period's date. Baby dust to all women looking for a baby. I was here reading people's comments before I took letrozole and I got encouraged. May every woman find encouragement in this."

9 / 10
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2140 Report
  • Milie
  • June 29, 2020

"I suffer from PCOS. My doctor prescribed me letrozole. After using it, I took a pregnancy test 2 weeks later which was positive. I am now 4 weeks pregnant. I have been trying to get pregnant for 6 years. I'm super happy. Please pray for me."

10 / 10
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1665 Report
  • Khuli
  • June 15, 2021

"Diagnosed with PCOS in Oct 2020, so I heard to go on metformin 850mg for 3 months because I didn't have periods. Luckily enough, periods came clockwise from Jan 2021. I was then prescribed letrozole 5mg from day 3 to 5. First round, nothing happened. Second round, I took the same dose again from day 3 to 5, and now I am 2 weeks pregnant. Letrozole does work. Please don't lose hope... pray it also works for you."

10 / 10
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693 Report

Frequently asked questions

  • Kay
  • Taken for less than 1 month
  • May 13, 2021

"I was diagnosed with PCOS. I have irregular periods and did not ovulate. Before I was given Letrozole, my OB recommended me to lose weight to increase my chances. I was 5'1" and 207 lb. It took me 5 months after dropping the weight from 207 to 174 lb. I finally was prescribed Letrozole. I did 2.5 mg from cycle day 2 to cycle day 11. Letrozole did help me ovulate on day 15 (peak) and 16 (high). I got pregnant on my first round of Letrozole. Please don't lose hope, thinking of you all."

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617 Report
  • Pandora
  • Taken for less than 1 month
  • December 11, 2020

"PCOS for years. After a 6cm ovarian cyst removal surgery, I took 2.5mg of Letrozole for days 2-6 of my period. I had read online that ovulation can be early, but the doctor advised it can happen at any time, really. I got pregnant after the first cycle of Letrozole. I pray for everyone to be as lucky and not give up!"

10 / 10
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585 Report

Are you taking this medicine?

  • Blessed...
  • Taken for less than 1 month
  • May 5, 2021

"Hubby and I started TTC in July 2020, but I wasn’t ovulating and no periods were present. In October 2020, I was prescribed Provera to induce a period and Clomid to release an egg. That did not work. I went on birth control for 3 months from December 2020 to March 2021 to calm my PCOS ovaries. At the beginning of my last birth control-induced period, I took one round of Letrozole and ovulated on the 14th/15th of March 2021 and fell pregnant on my first cycle. I am currently 9 weeks pregnant. Don’t give up hope!"

10 / 10
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523 Report
  • Fazz
  • Taken for less than 1 month
  • January 24, 2020

"I took letrozole for one month, two a day for 5 days while on my period. I am now 4 months pregnant. I was lucky it worked on me straight away. Took the pregnancy test 1 week prior to my next period and still showed pregnant! It does work, you just have to keep trying and praying for the best! Baby dust to everyone trying x"

10 / 10
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607 Report

More FAQ

  • Unknown
  • Taken for less than 1 month
  • September 21, 2021

"I write this to encourage someone! Reading about your experiences encouraged me too. I was diagnosed with PCOS in August 2021. My periods are so irregular, therefore, I was put on Medroxyprogesterone/Provera 10mg for 7 days to induce a period. My period started 2 days after stopping it. My doctor prescribed Letrozole 5mg day 2-6 of my cycle. I had a scan on day 13, and I had 2 dominant follicles. On day 14, my doctor gave me an Ovidrel shot to trigger ovulation. Now I’m 3 weeks pregnant. This was my first cycle of Letrozole. I pray for everyone reading this. Remain positive and expect the best."

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378 Report
  • RAano
  • September 30, 2020

"Diagnosed with PCOS since April 2018. Started Femara from July 2020 along with HCG shots. No luck in the first cycle. Miracle happened when I took the same medication for the second cycle. 5 weeks pregnant now. Just 2 cycles of Femara and good news is here. Best wishes to all the ladies."

10 / 10
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469 Report
  • Aimsley
  • Taken for less than 1 month
  • February 6, 2021

"I was unable to ovulate on my own due to hormonal imbalance/PCOS. After trying to conceive for almost 20 years and doctors not fully addressing my infertility issues, I found a doctor that prescribed me Letrozole. I successfully ovulated from left ovary on cycle day 17 and then had a second successful ovulation from the right ovary on cycle day 19. Both were confirmed from a Transvaginal ultrasound. Here I am several days late but waiting 3 more days until testing for the most accurate results. Baby dust to everyone trying! Dosage was 2.5mg starting on cycle day 3. Taken for 5 days."

10 / 10
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337 Report
  • Ubaid...
  • Taken for less than 1 month
  • July 13, 2021

"I have PCOS since 2018 and even hypothyroidism. I knew I was not ovulating, so I went to my gynecologist and discussed my history. She gave me Letroz 2.5 tablet from the 3rd day of the cycle to the 7th day, and I went for follicle scanning. The doctor said everything is fine, but unfortunately, there was no pregnancy. Now I'm on my 2nd round of Letroz with the same dose. I am hoping for the best. I pray for every lady who is trying to get pregnant; may their wish get fulfilled..!!"

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283 Report
  • Anonymous
  • Taken for 1 to 6 months
  • November 21, 2021

"Everything was normal, regular period, proper ovulation. Still, failed to get pregnant. We tried for 6 months. I took letrozole 2.5 mg twice a day from day 3 to 7, and in the same month, I got pregnant. In fact, after 7 weeks, I found it is twins, and now I am 3 months pregnant. So, this medicine works. In my case, maybe it induced more than one egg. Whatever, but this medicine works for natural conception."

10 / 10
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254 Report
  • Anonymous
  • Taken for 1 to 6 months
  • July 29, 2020

"I had been trying to get pregnant for 2 years. Did a few rounds of Clomid without results. Got diagnosed with PCOS. Did one round of Letrozole 5 mg and trigger shot without results. For round two, my doc upped it to 7.5 mg plus trigger shot, and it was successful! Daughter is now 1 year old, and we are trying again starting at 7.5 mg. Experiencing depression, fatigue, and intense dreams. Baby dust to all!"

7 / 10
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313 Report
  • Ishii
  • Taken for 1 to 6 months
  • May 7, 2020

"My fertility doctor prescribed me letrozole 2.5 mg for 3 months. So far, I have just completed my first cycle. My periods got delayed by 3 days. I was about to take a pregnancy test and saw spotting. It's sad, but I am not going to lose hope. Will try again. Wish me luck."

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287 Report
  • Raj
  • Taken for less than 1 month
  • December 3, 2020

"I tried letrozole for the first time and I conceived. I'm now 4 months pregnant - it’s magical for me."

10 / 10
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454 Report
  • Nicky
  • Taken for 1 to 6 months
  • January 18, 2021

"I used Femara (letrozole) 2.5mg for cycle day 3-7 for the first month, then the second month 5mg cycle day 3-7, but nothing. Until 3rd month, same dose 5mg cycle day 3-7 I got my first positive! Fingers crossed everything will be okay! Praying for all of you! I was going to stop at the second month, because I did have bad side effects but something told me to keep going!"

10 / 10
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229 Report
  • Anonymous
  • Taken for 1 to 6 months
  • November 7, 2020

"Has anyone used letrozole for 6 months, ovulated but not conceived?"

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440 Report
  • JPano
  • Taken for less than 1 month
  • September 9, 2020

"I have PCOS and have struggled with my irregular periods all my life. In 2017, I TTC and used Letrozole for one cycle... 2 pills a day for 5 days and BOOM! Preggo! After trying for 5 years, it was a miracle pill! Now I want baby number 2... to my surprise 3 years older and the same medication has the opposite effect. February 2020, did Round one, one pill for 5 days. No luck. Then Covid hit! Smh. Started again in Aug 2020, round 2, 2 pills for 5 days. I figured this was the same dosage as baby#1 so it would definitely work and nothing. My heart was broken.. no luck again!? Currently doing round 3. Doctor increased the pills to 3 a day for 5 days.. Getting checked next week and hopefully the trigger shot will help. I can say it works from past experience but I honestly believe age and dosage has a lot to do with it. Wish me luck! And wishing you all the best.. keep your heads up.. it can still happen!"

10 / 10
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191 Report
  • Sarah
  • Taken for less than 1 month
  • December 27, 2021

Femara (letrozole) "Had irregular periods and sudden weight gain, when consulted I got to know I have PCOS. I was advised to try for pregnancy as it might get difficult for me to conceive if I delay. I consulted many doctors, different doctors different advises!! I started dieting and exercise but nothing worked! I was then told to start glucophage 500 mg and femara on my periods days 2-5. I had no side effects. With the grace of almighty I conceived that month itself and have twin baby boys now.."

10 / 10
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131 Report
  • Sjano
  • Taken for less than 1 month
  • March 2, 2021

"I was diagnosed with PCOS 3 months ago after going to a fertility clinic, although I thought I had it when I was admitted to a hospital 4 years ago with a cyst that popped and made me very sick! The doctors just shrugged it off, and this happened twice! I’ve just started taking letrozole 5mg/day 2-6 and just received my smiley face!! Side effects were bad headaches that I couldn’t shake off and hot sweats. Later on, before I ovulated, I felt like my ovaries were going to pop (googled this thinking it was going to happen), so fingers crossed my next cycle will be the one, and we will get our first BFP! For those TTC, I send lots of baby dust your way, and for those who are already there, I wish you a happy, wonderful pregnancy."

10 / 10
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158 Report
  • Lily
  • Taken for 1 to 6 months
  • December 30, 2021

"Hello ladies! If you are checking the reviews for letrozole that means you are here to find out if it helped in conceiving for others. I am suffering from PCOS. My cycles are regular and also ovulation would happen in all the cycles. But the quality of eggs were not so good. So I decided on taking the letrozole. 1st month I took from cycle day 2-7 (5mg). Got my periods. I wasn’t really disappointed because whatever medicines you take, it takes some time for your body to adjust. I continued the letrozole for 2nd cycle. Just exactly on my expected period date I had cramping and brown spotting. No periods! As I mentioned I had a very regular cycle despite of PCOS, I waited for a week. And took a test! Booom I saw my 1st BFP at 5 weeks. For ladies who are trying to conceive, remember that not everyone’s body is same. Just have faith and keep trying."

10 / 10
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126 Report
  • Ash
  • Taken for less than 1 month
  • September 25, 2019

"Doctor started me on Clomid to help me get pregnant. Did that for 2 months. Then doctor said I didn’t ovulate the last month, so she then started me on letrozole. Took those days 3-7, and now I’m 9 weeks along."

10 / 10
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206 Report
  • Des
  • Taken for less than 1 month
  • January 18, 2021

Femara (letrozole) "Had my 1st round of Femara in December. I did ovulate for the 1st time that I’m aware of in a long time due to PCOS. I did end up pregnant, but sadly had a chemical pregnancy around 3 weeks. I’m thankful that it did work for us and I was able to conceive. Now is the hard part of figuring out where to go from here. Prayers and love to all!"

10 / 10
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160 Report
  • Nano
  • May 12, 2020

"I was trying to get pregnant for 10 months. I went to an infertility specialist. Although I didn't have PCOS, I took letrozole for three months and got pregnant on the third cycle. Blessed with a baby. I don't understand, if I didn't have PCOS, how did it work? Another point to note is I was given a tablet of a local brand, and since I couldn't find that brand, I took Glaxosmith letrozole on the third cycle and got pregnant."

9 / 10
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183 Report
  • Rubia...
  • February 1, 2021

"I am 17 weeks along with my first baby after 5 cycles of letrozole. I was trying to conceive for years. Of course, it's a group of things that need to be changed in your mind: Think positively. Everyone was getting pregnant before me, and I was putting myself down. We all have our own time to shine; be happy for everyone else. Have a diary on an app so you can log your symptoms, days you had sex, etc. I lost a ton of weight before I got pregnant, so eat better, cut down on alcohol. And all of that helped to conceive. Good luck, ladies. You will get there also. x"

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154 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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