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Letrozole Dosage

Medically reviewed by Drugs.com. Last updated on May 6, 2024.

Applies to the following strengths: 2.5 mg

Usual Adult Dose for Breast Cancer

2.5 mg orally once a day

Duration of therapy:


Uses:

Usual Adult Dose for Breast Cancer - Adjuvant

2.5 mg orally once a day

Duration of therapy:


Uses:

Renal Dose Adjustments

CrCl 10 mL/min or greater: No adjustment recommended.
CrCl less than 10 mL/min: Data not available

Liver Dose Adjustments

Mild to moderate hepatic impairment: No adjustment recommended.
Severe hepatic impairment with cirrhosis: 2.5 mg orally every other day
Noncirrhotic with elevated bilirubin: Data not available

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

This drug is anticipated to be dialyzable; however, no dose adjustment guidelines have been reported.

Other Comments

Administration Advice:


Storage Requirements:
Store this drug at room temperature (20 to 25 Celsius) and protect from light.

General:

Monitoring:

Patient Advice:
This drug may cause fatigue, dizziness, and drowsiness; avoid driving or any other potentially dangerous activity until you know how this drug affects you.

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.