I've been taking Xarelto for 6 months. Anyone have acute muscle and joint pain on this drug?

I am so grateful that I found this forum. I started taking Xarelt four months ago because of a DVT caused by cancer surgery. Three weeks ago I woke up with terrible muscle stiffness and pain all over my body, particularly in my neck, back and limbs. I have frequently been reduced to tears by the pain and fear this has caused me. I am planning to ask my oncologist next week if I can stop taking the drug.

I have been on xarelto since June 15th, 2017. Since beginning the 20mg once a day I have had joint and muscle pain. I spoke with my doctor and he said he's never had a xarelto patient complain of this. I'm so glad I found this discussion board! I called Janssen Pharmaceutical today. They confirmed that during the clinical trials 1.7% of the patients taking 10mg had this complaint. But they didn't have any other information since they don't follow the patients after the trials are completed. My doctor said for a short term during the worse days it was ok to take 1 Aleve 2x's a day. I started today and the leg pain has lessened. The elbow pain and stuff neck did not diminish. I will keep you posted.

I have had similar, but not as severe as some, side effects of Xarelto. I've been on Xarelto, as a result of pulmonary emboli, for nearly two years. Since taking Xarelto I've experienced joint pain and swelling as well as diminished energy. Unlike some who indicate that their pain goes away the longer one has taken Xarelto, I am experiencing the opposite. The longer I am on Xarelto the more pain and swelling I experience. Before taking Xarelto I had no pain and swelling in the joints even after working out and playing basketball.

I was off Xarelto for about a week before they removed the vena cava filter they had inserted to stop blood clots from reaching my lungs. During this period the pain and swelling in my joints went away and my wife noted that seemed to have a lot more energy. I felt like I had my old self back again.

I'm still debating whether to stop taking Xarelto and start taking aspirin and Turmeric BCM-95 or continue with Xarelto.

As a physician, I have seen this complaint. One patient has the MTHFR mutation which caused a blood clot. These patients do not utilize Vitamin B12 and Folic Acid properly. Do any of the people who have written about their muscle spasms and joint pain also have this defect?

I have been taking Xerelto for almost two years. I started experiencing pain shortly after starting this medication too. My pain was not like charley horse or leg cramps but severe aching & more like what some diabetics describe as diabetic nerve pain. I couldn't pinpoint a specific spot that hurt. The pain just ran up and down my legs. Nothing seemed to help. I have never had an issue with my sugar levels nor bad arthritis or joint pain. This leg pain was bad tho, and it worsened at night. When I finally went to the doctor about it, he acted like he was not convinced it was the Xerelto causing it and was very reluctant to change my medication. He suggested, instead, I try taking Gabapentin along with the Xerelto. It started helping immediately and I'm still taking both medications. Occasionally, I will have a little pain in my legs but it is no longer severe.

I am using the Xarelto starting package, for the first three weeks ( 15mg twice per day) I did not experience any major side effect, just occasionally felt weak/tired. I've taking the 20mg dosis for less than a week and i've experiencing pain on my right knee. It's not too intense but it bothers me. Also, one night I woke up with pain on my right leg, it was totally numbed, I had to get up and walk around the room. I hope this does not get worse.

I got off the Xarelto and the pain slowly went away. They need to do more research on this drug. Too many people have this side effect. I remember night time being the worst. I have no side effects on Eliquis. I think it's worth a try. It also comes in two different doses just depending on how much you need.

I did. I've been on it for 3 years. Got muscle and joint pain in a similar time frame as you. Called my clot doc and he said it should go away after a while.

Took a while but it did. Hang in there!

I take xarelto after when I go into afib and for 30-60 days after and every time I go on xarelto I have much problems with muscle and joint pain even have problems lifting my arms,my back is so stiff I can not lean back for the the pressure on it,my knees and legs have pain I can no be on my feet for more than 15-30 without minutes

Hi, are you still on Xarelto and has the pain eased if so? I have been on it for 18 months now and just recently experiencing calf pain and like burning sensation in both legs - I don't want it to get worst but don't want the hassle of switching drugs - I have to be on them for life after my second dvt! Really don't want warfarin because of all the monitoring but my mum is on this and has had no side effects - what is the answer??

I have been on xeralto for almost three years now and am experiencing everything others have described. I've gone from a very active person to not being able to get out of bed at times. Many sleepless nights because the pain is excruciating at night. Every joint and muscle in my body hurts. I dread going to bed at night because of what I'm going to go through. I have brought it up to my doctors, but their response is that they don't see muscle and/or joint pain listed as a side effect of xeralto, so it's not pursued. I was discovered to have the MTHFR after getting blood clots in both lungs after a surgery which is why my dr put me on xeralto in the first place. My husband actually ran across this thread while looking up side effects for xeralto. He showed it to me, and I finally feel like someone believes me. Now, what's the fix???

Swimming in a heated pool will help everyone with joint pain

Been taking Xarelto for 15 months now, 20 mgms daily it creates a build up of Uric Acid which in turn causes severe joint pain. About every 6 weeks I take a drug called Colchacine which clears out the Uric Acid and then I am OK for a few weeks until it builds up again. I have to take the Xarelto to prevent blood clotting, there are other similar drugs but who knows what side affects they will cause, better the devil you know I suppose & to be honest if it prevents another stroke then I will put up with it

I have been taking Xarelto for 5 weeks. Two days after starting Xarelto I had a full blown gout attack on my right foot and ankle. I have a DVT in the left leg thus why I am taking Xarelto. I was given the methylpredisone pack and the gout subsided while I was taking. After 2 days I was back on another prednisone pack because again the pain was so bad I could not walk. After finishing this pack about 7 days later my right knee had tremendous pain. Again I took a third prednisone pack and the knee was pain free for 4 days. Finished it yesterday and I am in so much knee pain again I am on crutches. I cannot sleep due to the pain. I am on 7.5 mg of Norco and it is not working. Doctor thinks the knee pain is from compensating for the pain in the foot for 4 weeks. My doctor's won't even consider Xarelto as the source for the gout and knee pain. I haven't had a gout attack in over 2 years. I have 7 more weeks to go on the Xarelto. What other choice do I have???