I've been taking Xarelto for 6 months. Anyone have acute muscle and joint pain on this drug?

I had a massive PE in Sept 2017, have been on Xarelto 20mg ever since. First 6 months, no problems. Then the leg and foot pain began... cramping, numbness, tingling, especially at night. My podiatrist prescribed Gabapentin for my broken foot and resulting nerve damage, and it helped ease the leg pain as well. I also take Hylands Leg Cramp at night and it does help. The problem though with the Gabapentin is it makes me a little wobbly, so I am tapering to only 2 - 100mg per day and it helps, but the leg & foot pain is a little worse! AAGH! Don't know what else to do!

Yes, Xarelto has caused a terrible RA flare for me after only one week plus disabling headache pain. I had to stop the Xarelto. My entire body reacted negatively to this med. I thought I was dying.

Hi Beth, I had a leg DVT in December 2017 and was given Elliquis. I went to the ER because my calf had been swollen for a week. I walked in fine with no pain other than the swelling. They prescribed Elliquis and in two days my ankles and knees were in extreme pain. They swelled up and I couldn't stand without going through a lot of pain. Went back to the Dr. and switched to Xarelto, but the swelling and pain didn't get better. I switched to Coumadin and all was resolved. After 6 months now, my Dr. recommends I go back to Xarelto, but I don't want to go through that pain again. I've seen lots of bad comments about both of these new drugs for DVT, but on some people they have no problems. It's strange. I got tested and am Factor V Laiden, so I guess I'm prone to clotting easily. It also may have something to do to me having bad reactions to these drugs. I just got your post, so hope this helps. Robert

Yes I have been taking xarelto for afib for 9 mos. And I just started getting severe cramping. Now , the pain is radiating over to my left side. Its coming in spasms. Its an extremely sharp pain. I was in the er today with it they ran 2 different cat scans. One of my kidneys and one of my stomach. They were both clear. I happened to have a low dose xanax and I took one. It releived my pain within minutes
now o will call my cardiologist. And ask him what am I going to take for pain.

Most definitely. When I want to walk the dog, go shopping or any other amount of time I'll be walking around it really takes a toll on my legs. I also notice I have a lot of joint pain in the mornings even before I get out of bed.

Shoulder joint and elbows constantly hurt. Carrying a shopping bag is very painful too.

Was on it for two years, serious joint pain sometimes I was on crutches, changed to Eliquis better but not good.
Doctor switched me back onto Warfarin been on it for a month all my aches & pains have gone.
Gerry W

Hello! I need some advice. I've been on 20 mg once a day for 12 + months now. I am kind of stressed in life with a new job. weekend before starting new job I got a full on migraine which is common for me. It subsided into a tension headache that I've had for over 6 weeks now and i'm so concerned its a brain bleed or something. Could it simply be a tension headache like a lot of the research shows. my dr didn't seemed too concerned . i'm going to chiro and massage. pressure like at temples, forehead and at top of head on right side. waking up with it most days.

Thanks !!

I've been taking Xarelto for approximately one month. After about one week on the drug, I began experiencing severe excruciating joint and muscle pain in my right hip, when I walk; two weeks later and now it's in both hips. Never experienced this before. Dr says its arthritis, but, not caused by xarelto. I disagree! I believe it is triggered by the Xarelto. My body seems to be very sensitive to new drugs. I thought Eliquis was bad (hives, blurred vision, throat swelling) when I tried that, but this one side effect of Xarelto is unbearable even with NSAIDS, approved by oncologist.

Yes, I was on Xarelto for just short to 3 months.
I suffered excruciating pains in pectorals, legs, calves ,backs of knees, spine and back. My hip joint collapsed into a grinding pain upon any rotation or load. Hurts like hell!!! My back collapsed, and accordingly, I cannot carry any weight. because of both, I cannot walk distances. Post halting Xarelto I was almost totally immobilized. Physician requested I power through it. I told him I will die!!! It has been about 2 months since getting off Xarelto, and my hip is still dysfuctiona (REQUIRE HIP REPLACEMENT), my back has collapsed in three areas (the pain is great). the back of knee pain is still great. My legs are very, very weak. It is almost impossible to get off of a couch or off of the ground. AT TIMES, WHILE WALKING MY HIP, BACK, KNEE,OR MUSCLES SUDDENLY HURT, ALMOST KNOCKING ME TO THE GROUND!!! It appears damage may be permanent.!

I'm was fit and a-fib corrected [fingers crossed]. After one year of Xarelto, my ER visits due to joint pain started last summer, with 20 blood tests for gout, LYME, Hashimotos, etc. Also numerous visits with specialists in infectious diseases, neurologists, rheumatologists, etc. The only two diagnosis were theoretical NOT certain. The pain flares come from nowhere and pop up in various locations: shoulder, back, ankle, even chest. Some are 5 on a 10 point scale and some are an agonizing 9-10. Today, I'm in the midst of another one in my ankle. So, in desperation, I 'google' "XARELO JOINT PAIN" and find all of you guys. Now I'm suspect since only 6 months ago, I was even jumping rope and running. Some days, I can't walk, sleep, or concentrate due to this pain... it's deep with no 'hot spots' like one could have from an injury or sprain.

I was put on Xarelto 6 days ago and my body now feels like one giant bone deep bruise. I have a clot in my right calf, so Xarelto was deemed the best option. Doctors are saying I need to be on it for at least 3 months. I have fibromyalgia and arthritis and this drug is making my life hell already. I cry when I think about how much worse it's likely to get. The Doctor switched my nsaid pain management pills to Tylenol 3/ codeine and man is that crap a bad joke. I can't hardly extend my arms, I'm getting light muscle cramps, my neck feels like it's grinding rocks, I'm so tired all the time and my moods have hit an all time low. I'm not sure why 3 months is the magic #. I would think it would very person to person. I mean if John Doe had a 2" clot, Mary Jones had a 1" clot and I had a 1/2 " clot, why would we each need 3 months on blood thinners? The doctor doesn't even want another ultra sound for 6-8 weeks to check on my clot. Any ideas on how to help relieve this pain?