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Medications for Sinusitis

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Augmentin 5.3 149 reviews for Augmentin to treat Sinusitis Rx B N
Generic name:
amoxicillin / clavulanate systemic
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
amoxicillin 4.8 21 reviews for amoxicillin to treat Sinusitis Rx B N
Generic name:
amoxicillin systemic
Brand name:
Amoxil
Drug class:
aminopenicillins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
amoxicillin / clavulanate 4.9 297 reviews for amoxicillin / clavulanate to treat Sinusitis Rx B N
Generic name:
amoxicillin / clavulanate systemic
Brand names:
Augmentin, Augmentin XR, Amoclan
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
prednisone 7.6 54 reviews for prednisone to treat Sinusitis Rx C N
Generic name:
prednisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cefdinir 3.8 157 reviews for cefdinir to treat Sinusitis Rx B N
Generic name:
cefdinir systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Azithromycin Dose Pack 6.3 16 reviews for Azithromycin Dose Pack to treat Sinusitis Rx B N
Generic name:
azithromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
azithromycin 6.7 145 reviews for azithromycin to treat Sinusitis Rx B N
Generic name:
azithromycin systemic
Brand names:
Azithromycin Dose Pack, Zithromax
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
levofloxacin 5.3 175 reviews for levofloxacin to treat Sinusitis Rx C N
Generic name:
levofloxacin systemic
Brand name:
Levaquin
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zithromax 8.2 30 reviews for Zithromax to treat Sinusitis Rx B N
Generic name:
azithromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Levaquin 5.5 123 reviews for Levaquin to treat Sinusitis Rx C N
Generic name:
levofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
clindamycin 6.7 33 reviews for clindamycin to treat Sinusitis Rx B N
Generic name:
clindamycin systemic
Brand names:
Cleocin, Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate
Drug class:
lincomycin derivatives
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cefuroxime 6.6 45 reviews for cefuroxime to treat Sinusitis Rx B N
Generic name:
cefuroxime systemic
Brand names:
Ceftin, Zinacef
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
clarithromycin 5.4 197 reviews for clarithromycin to treat Sinusitis Rx C N
Generic name:
clarithromycin systemic
Brand name:
Biaxin XL
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ciprofloxacin 7.0 43 reviews for ciprofloxacin to treat Sinusitis Rx C N
Generic name:
ciprofloxacin systemic
Brand names:
Cipro, Cipro I.V., Cipro XR
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Cipro 4.2 12 reviews for Cipro to treat Sinusitis Rx C N
Generic name:
ciprofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Amoxil 5.0 2 reviews for Amoxil to treat Sinusitis Rx B N
Generic name:
amoxicillin systemic
Drug class:
aminopenicillins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
sulfamethoxazole / trimethoprim 5.1 75 reviews for sulfamethoxazole / trimethoprim to treat Sinusitis Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Brand names:
Bactrim, Septra, SMZ-TMP DS, Septra DS, Co-trimoxazole, Sulfatrim Pediatric
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Avelox 6.4 60 reviews for Avelox to treat Sinusitis Rx C N
Generic name:
moxifloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ceftin 6.8 18 reviews for Ceftin to treat Sinusitis Rx B N
Generic name:
cefuroxime systemic
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Bactrim 4.6 22 reviews for Bactrim to treat Sinusitis Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cefzil 7.0 3 reviews for Cefzil to treat Sinusitis Rx B N
Generic name:
cefprozil systemic
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
Cleocin 7.8 4 reviews for Cleocin to treat Sinusitis Rx B N
Generic name:
clindamycin systemic
Drug class:
lincomycin derivatives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
moxifloxacin 6.4 66 reviews for moxifloxacin to treat Sinusitis Rx C N
Generic name:
moxifloxacin systemic
Brand names:
Avelox, Avelox I.V.
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Septra Rate Add review Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cefixime 9.0 2 reviews for cefixime to treat Sinusitis Rx B N
Generic name:
cefixime systemic
Brand name:
Suprax
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cefpodoxime 9.0 2 reviews for cefpodoxime to treat Sinusitis Rx B N
Generic name:
cefpodoxime systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
chlorpheniramine / pseudoephedrine 8.5 3 reviews for chlorpheniramine / pseudoephedrine to treat Sinusitis Rx/OTC C N X
Generic name:
chlorpheniramine / pseudoephedrine systemic
Brand names:
Deconamine, Allerest Maximum Strength, Dicel, LoHist-D, Triaminic Softchews Cold and Allergy
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Suprax 10 1 review for Suprax to treat Sinusitis Rx B N
Generic name:
cefixime systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Augmentin XR 7.3 3 reviews for Augmentin XR to treat Sinusitis Rx B N
Generic name:
amoxicillin / clavulanate systemic
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cefprozil 3.1 13 reviews for cefprozil to treat Sinusitis Rx B N
Generic name:
cefprozil systemic
Brand name:
Cefzil
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
dexchlorpheniramine / dextromethorphan / pseudoephedrine 9.0 2 reviews for dexchlorpheniramine / dextromethorphan / pseudoephedrine to treat Sinusitis Rx/OTC C N X
Generic name:
dexchlorpheniramine / dextromethorphan / pseudoephedrine systemic
Brand names:
Abatuss DMX, Bromatan Plus, Deltuss DMX, SuTan-DM
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
SMZ-TMP DS 7.5 3 reviews for SMZ-TMP DS to treat Sinusitis Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
ampicillin Rate Add review Rx B N
Generic name:
ampicillin systemic
Drug class:
aminopenicillins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Biaxin XL Rate Add review Rx C N
Generic name:
clarithromycin systemic
Drug class:
macrolides
For consumers:
dosage, interactions, side effects
Cipro I.V. Rate Add review Rx C N
Generic name:
ciprofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
Cipro XR Rate Add review Rx C N
Generic name:
ciprofloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Septra DS 1.0 1 review for Septra DS to treat Sinusitis Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
Amoclan Rate Add review Rx B N
Generic name:
amoxicillin / clavulanate systemic
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cefaclor 10 1 review for cefaclor to treat Sinusitis Rx B N
Generic name:
cefaclor systemic
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ceftazidime Rate Add review Rx B N
Generic name:
ceftazidime systemic
Brand names:
Fortaz, Tazicef
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Cleocin HCl Rate Add review Rx B N
Generic name:
clindamycin systemic
Drug class:
lincomycin derivatives
For consumers:
dosage, interactions, side effects
Cleocin Pediatric Rate Add review Rx B N
Generic name:
clindamycin systemic
Drug class:
lincomycin derivatives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cleocin Phosphate Rate Add review Rx B N
Generic name:
clindamycin systemic
Drug class:
lincomycin derivatives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Co-trimoxazole Rate Add review Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Deconamine Rate Add review Rx/OTC C N X
Generic name:
chlorpheniramine / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
dextromethorphan / diphenhydramine / phenylephrine Rate Add review Rx/OTC C N X
Generic name:
dextromethorphan / diphenhydramine / phenylephrine systemic
Brand name:
Dytan-DM
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
diphenhydramine / phenylephrine Rate Add review Rx/OTC C N X
Generic name:
diphenhydramine / phenylephrine systemic
Brand names:
Benadryl Allergy Plus Congestion, Children's Triacting Night Time, Dytan-D
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Excedrin Tension Headache Rate Add review OTC N N X
Generic name:
acetaminophen / caffeine systemic
Drug class:
analgesic combinations
For consumers:
dosage, interactions, side effects
Fortaz Rate Add review Rx B N
Generic name:
ceftazidime systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tazicef Rate Add review Rx B N
Generic name:
ceftazidime systemic
Drug class:
third generation cephalosporins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zinacef Rate Add review Rx B N
Generic name:
cefuroxime systemic
Drug class:
second generation cephalosporins
For consumers:
dosage, interactions, side effects
Abatuss DMX Rate Add review Rx/OTC C N X
Generic name:
dexchlorpheniramine / dextromethorphan / pseudoephedrine systemic
For consumers:
dosage, interactions, side effects
acetaminophen / caffeine Rate Add review OTC N N X
Generic name:
acetaminophen / caffeine systemic
Brand names:
Excedrin Tension Headache, Excedrin Quick Tab
Drug class:
analgesic combinations
For consumers:
dosage, interactions, side effects
Allerest Maximum Strength Rate Add review Rx/OTC C N X
Generic name:
chlorpheniramine / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
ampicillin / sulbactam Rate Add review Rx B N
Generic name:
ampicillin / sulbactam systemic
Brand name:
Unasyn
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Avelox I.V. Rate Add review Rx C N
Generic name:
moxifloxacin systemic
Drug class:
quinolones and fluoroquinolones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Benadryl Allergy Plus Congestion Rate Add review Rx/OTC C N X
Generic name:
diphenhydramine / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Bromatan Plus Rate Add review Rx/OTC C N X
Generic name:
dexchlorpheniramine / dextromethorphan / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Children's Triacting Night Time Rate Add review Rx/OTC C N X
Generic name:
diphenhydramine / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Codimal DM Rate Add review Rx/OTC C N X
Generic name:
dextromethorphan / phenylephrine / pyrilamine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Deltuss DMX Rate Add review Rx/OTC C N X
Generic name:
dexchlorpheniramine / dextromethorphan / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
dextromethorphan / phenylephrine / pyrilamine Rate Add review Rx/OTC C N X
Generic name:
dextromethorphan / phenylephrine / pyrilamine systemic
Brand name:
Codimal DM
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Dicel Rate Add review Rx/OTC C N X
Generic name:
chlorpheniramine / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Dytan-D Rate Add review Rx/OTC C N X
Generic name:
diphenhydramine / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Dytan-DM Rate Add review Rx/OTC C N X
Generic name:
dextromethorphan / diphenhydramine / phenylephrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Excedrin Quick Tab Rate Add review OTC N N X
Generic name:
acetaminophen / caffeine systemic
Drug class:
analgesic combinations
For consumers:
dosage, interactions, side effects
LoHist-D Rate Add review Rx/OTC C N X
Generic name:
chlorpheniramine / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
oxacillin Rate Add review Rx B N
Generic name:
oxacillin systemic
Drug class:
penicillinase resistant penicillins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Sulfatrim Pediatric Rate Add review Rx D N X
Generic name:
sulfamethoxazole / trimethoprim systemic
Drug class:
sulfonamides
For consumers:
dosage, interactions, side effects
SuTan-DM Rate Add review Rx/OTC C N X
Generic name:
dexchlorpheniramine / dextromethorphan / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Triaminic Softchews Cold and Allergy Rate Add review Rx/OTC C N X
Generic name:
chlorpheniramine / pseudoephedrine systemic
Drug class:
upper respiratory combinations
For consumers:
dosage, interactions, side effects
Unasyn Rate Add review Rx B N
Generic name:
ampicillin / sulbactam systemic
Drug class:
penicillins/beta-lactamase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Frequently asked questions

View more FAQ

Topics under Sinusitis

Alternative treatments for Sinusitis

The following products are considered to be alternative treatments or natural remedies for Sinusitis. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical, cultural or anecdotal evidence linking their use to the treatment of Sinusitis.

Learn more about Sinusitis

Care guides

Symptoms and treatments

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

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