Spiriva Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Spiriva (tiotropium)	Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)	Albuterol	Enter another drug to compare

Spiriva (tiotropium)

Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)

Albuterol

Prescription only

Prescribed for COPD - Maintenance. Spiriva may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for COPD - Maintenance, COPD. Breztri Aerosphere may also be used for purposes not listed in this medication guide.

Prescription only

Albuterol helps people with asthma and certain other breathing disorders to breathe easier. While it is effective at relieving symptoms of asthma, it does not prevent asthma from getting worse... View more

More about Spiriva (tiotropium)

More about Breztri Aerosphere (budesonide / formoterol / glycopyrrolate)

More about Albuterol

Ratings & Reviews

Spiriva has an average rating of 5.9 out of 10 from a total of 122 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 30% reported a negative effect.

Breztri Aerosphere has an average rating of 6.9 out of 10 from a total of 120 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 13% reported a negative effect.

Albuterol has an average rating of 3.2 out of 10 from a total of 387 ratings on Drugs.com. 19% of reviewers reported a positive effect, while 70% reported a negative effect.

View all 122 reviews

View all 120 reviews

View all 387 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Dry mouth (13.9%)
Cough (6.6%)
Insomnia (5.7%)
Blurred vision (4.9%)
Chest pain (4.9%)
Cramps (4.9%)
Hoarseness (4.9%)

View all Spiriva side effects

Shortness of breath (5.8%)
Anxiety (5.0%)
Cough (4.2%)
Hoarseness (3.3%)
Sore throat (3.3%)
Increased heart rate (2.5%)
Insomnia (2.5%)

View all Breztri Aerosphere side effects

Bad taste (3.9%)
Anxiety (3.1%)
Shortness of breath (2.8%)
Tremors (2.3%)
Dizziness (1.8%)
Headaches (1.6%)
Increased heart rate (1.6%)

View all Albuterol side effects

Drug Class

Anticholinergic bronchodilators

Bronchodilator combinations

Adrenergic bronchodilators

Generic Availability

Lower cost generic approved

No lower cost generic approved

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	5 capsule
Strength	18 mcg
Per unit^*	$14.99
Cost^*	$74.96

View all Spiriva prices

Quantity	5.9 gram(s)
Strength	160 mcg-4.8 mcg-9 mcg/inh
Per unit^*	$67.99
Cost^*	$401.16

View all Breztri Aerosphere prices

Quantity	75 mL
Strength	2.5 mg/3 mL (0.083%)
Per unit^*	$0.28
Cost^*	$20.75

View all Albuterol prices

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Dosage Forms

Inhalation capsule

Inhalation aerosol

Inhalation aerosol
Inhalation solution
Oral syrup
Oral tablet
Oral tablet, extended release

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

144 hours

N/A

6.5 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 111 drugs are known to interact with Spiriva:

109 moderate drug interactions (610 brand and generic names)
2 minor drug interactions (8 brand and generic names)

A total of 954 drugs are known to interact with Breztri Aerosphere:

92 major drug interactions (303 brand and generic names)
830 moderate drug interactions (3463 brand and generic names)
32 minor drug interactions (543 brand and generic names)

A total of 424 drugs are known to interact with Albuterol:

19 major drug interactions (61 brand and generic names)
386 moderate drug interactions (1641 brand and generic names)
19 minor drug interactions (194 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

You should avoid the regular consumption of large amounts of grapefruits and grapefruit juice while... View more
Ask your doctor before using glycopyrrolate together with alcohol. Use alcohol cautiously... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

January 30, 2004

July 23, 2020

May 01, 1981

WADA Class View classifications

N/A

More Information

Patient Resources

Spiriva uses

Breztri Aerosphere uses

Professional Resources

Prescribing information

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Spiriva Alternatives Compared

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