Comparing Nexium vs Protonix
| Nexium (esomeprazole) | Protonix (pantoprazole) |
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| Nexium (esomeprazole) | Protonix (pantoprazole) |
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Prescription only
Nexium is an acid-suppressing agent used to treat conditions associated with excessive stomach acid production, such as gastroesophageal reflux (GERD) and stomach ulcers. Nexium is available orally... View more |
Prescription only
Protonix is used to treat erosive esophagitis associated with gastroesophageal reflux disease (GERD), hypersecretory conditions including Zollinger-Ellison (ZE) syndrome, and for the maintenance of... View more |
Related suggestions Helicobacter Pylori Infection
Erosive Esophagitis
Barrett's Esophagus
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| More about Nexium (esomeprazole) | More about Protonix (pantoprazole) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Nexium has an average rating of 6.2 out of 10 from a total of 211 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 33% reported a negative effect. |
Protonix has an average rating of 7.2 out of 10 from a total of 83 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Nexium side effects |
View all Protonix side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Nexium prices |
View all Protonix prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other esomeprazole brands include: Nexium 24HR, Nexium IV | Other pantoprazole brands include: Protonix IV | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1.5 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 214 drugs are known to interact with Nexium:
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A total of 181 drugs are known to interact with Protonix:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
February 02, 2000 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.