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Nexium and Heart Palpitations: What Users Say

Heart palpitations: mentioned by 12 users (5.7%)

Based on user experiences from 211 Nexium reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 11.8%
diarrhea 11.4%
nausea 10.0%
headaches 9.0%
fatigue 7.1%
dizziness 5.7%
heart palpitations 5.7%
insomnia 5.2%
constipation 4.7%
tremors 4.7%

Reviews for Nexium

Commonly mentioned side effects
  • HWa...
  • Taken for 1 to 6 months
  • May 2, 2021

For GERD "Thank you, thank you!! I thought I was going crazy!!!!! Massive anxiety attacks, high blood pressure, heart palpitations, massive headaches, worst cramps ever... so many ED visits, so many doctors' visits, ultrasounds, stress tests! My doctors thought I was a hypochondriac, that I was faking it... they put me on so many prescriptions! So I decided to go off all my medications. I have felt the best for the last few weeks until yesterday when I got heartburn, so I took my Nexium tablet... within 30-40 mins I was laying in bed so bloody sick! Blood pressure was up, headaches kicked back in, massive fatigue. So I googled and found this review pages! I have now chucked out my tablets and I'll find something else to stop the heartburn! Thank you, thank you!!"

1 / 10
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170 Report
  • Pet...
  • November 18, 2020

For GERD "Glad that I have found this site. Got prescribed these meds from ER with suspected gastritis. Used them for 8 days (40mg x 2 times a day). Like everyone else, after 2 days' use, I was severely debilitated - the only thing I could do was to lie down all day, every day whilst using them. Got all the regular symptoms described by others - shortness of breath, anxiety attacks, palpitations, light-headedness, constant bloated feeling, etc. 3 visits to ER - nil issues found with heart, bloods/x-rays done all clear. Had gastroscopy done - all clear - nil issues at all - shouldn't have taken these meds to begin with. 5 days on after stopping them, I'm still feeling weak, anxious, and consistently burping/feeling bloated. Research has shown these effects (even for short-term use) can last up to 2 weeks - I've gone cold turkey and will never take these meds again. Previous to this, I never had these symptoms."

1 / 10
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  • YLa...
  • Taken for less than 1 month
  • December 12, 2018

For GERD "My doctor prescribed Nexium 40mg after an endoscopy result that showed I have hiatus hernia and gastritis. The next day, I woke up feeling terrible, with stomach discomfort and burping the whole time. I never had these symptoms before taking Nexium. By the evening, my whole body felt weak, I couldn't sleep, had anxiety, and heart palpitations. The next morning, things were slightly better, but because I didn't know it was the effect of the medicine, I continued taking it. By the evening, I felt like I was dying. The next morning, I was admitted to the hospital for an IV drip. I stayed a night, and the doctor said it could probably be a viral infection. After discharge, I took Nexium again. True enough, the whole attack happened again. I didn't take it today, but the side effects are still there. Hopefully, they will go away soon. It's unbearable. This drug has done more harm than good for me and is not helping at all."

1 / 10
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101 Report

Frequently asked questions

  • Hor...
  • Taken for 1 to 6 months
  • November 16, 2021

For GERD "I have been taking this medication for the past 4 months, 20 mg but recently up to 40 mg. I wanted to stop taking it a while ago as I felt it wasn’t working, but the specialist insists on taking it. Since taking 40 mg, I have felt so nauseous, have headaches, and feel so dizzy. Since reading these reviews, I have only just put 2 and 2 together. This drug is the cause of all the weird symptoms I’ve been experiencing for the past few months. I’ve had multiple doctor visits due to having bad palpitations, chest tightness, and breathlessness very regularly for the past few months. Had heart ultrasound and multiple ECGs, doctors have said my heart is fine and it’s my anxiety, yet it has nothing to do with my anxiety. This is the best I have ever felt mentally. These symptoms just hit me randomly. Before this drug, I didn’t feel like this. It’s truly scary thinking about all the symptoms these drugs cause and doctors insist it’s fine. I’m going to stop taking this ASAP. NEVER AGAIN!"

1 / 10
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  • Eso...
  • Taken for less than 1 month
  • June 28, 2022

For GERD "Omg, I am so glad I found this website!! I took Nexium 20mg 24hr for 2 weeks, then my GI put me on 40mg, and after taking it for 1 week, I thought I was going crazy with all these horrible side effects such as anxiety, muscle twitches, bloating, belching, insomnia, heart palpitations, and much more!! Ended up in the ER, did an ultrasound and bloodwork, and nothing came up, so they must have thought I was faking it. It raises my blood pressure, makes me so fatigued that some days I couldn’t even get out of bed. My mouth and eyes were so dry, brain fog, and confusion…. Just HORRIBLE!! I’m so glad I went on here and found all these reviews, I will stop taking it!"

1 / 10
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  • Ger...
  • Taken for less than 1 month
  • July 10, 2021

For GERD "I took this 20 mg twice a day as recommended by my doctor, and within 4 days I had palpitations, insomnia, extreme anxiety, dizziness, nausea, and pins and needles in my neck and legs. Worse was at night when trying to lie down, when there would be pressure in my head and chest, and violent dizziness and nausea. I had two weeks of only sleeping 2 hours a night and peaked with 2 successive nights of no sleep and a visit to Accident & Emergency. Suddenly realized it was the tablets and stopped them, effects slowly going and sleeping at last."

1 / 10
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  • Ree...
  • Taken for less than 1 month
  • September 28, 2021

For Helicobacter Pylori Infection "I don't usually write reviews, but I think this will help someone out there. Nexium nearly finished me! Three months of palpitations (high blood flow and high pulse rate) as if my heart will shut down the next minute. Can't sleep except aided by music. Can't sleep on my left side. Went for several ECGs (which always revealed tachycardia) then finally an echocardiogram, which was quite revealing. Heart is okay, but something keeps triggering my complaints. Doctor placed me on meds, and ultimately, by God's grace, I'm okay now. If I sight this drug anywhere, I will run."

6 / 10
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  • Ree...
  • Taken for less than 1 month
  • September 28, 2021

For Helicobacter Pylori Infection "I don't usually write reviews, but I think this will help someone out there. Nexium nearly finished me! Three months of palpitations (high blood flow and high pulse rate) as if my heart will shut down the next minute. Can't sleep except aided by music. Can't sleep on my left side. Went for several ECGs (which always revealed tachycardia) then finally an echocardiogram, which was quite revealing. Heart is okay, but something keeps triggering my complaints. Doctor placed me on meds, and ultimately, by God's grace, I'm okay now. If I sight this drug anywhere, I will run."

6 / 10
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7 Report
  • Nin...
  • January 4, 2018

For Helicobacter Pylori Infection "It is good medication, as it helped me. It was 14 days of treatment, but its side effects, if they were strong for me, I suffered from anxiety, agitation, and tachycardia. But when the treatment was finished, the symptoms disappeared gradually."

6 / 10
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  • Jes...
  • September 24, 2015

For GERD "I took one dose, and 30 minutes later, I was in real trouble! Rash, itching, tachycardia, abdominal cramping, nausea, vomiting, diarrhea, chills, etc."

1 / 10
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47 Report
  • Mer...
  • Taken for less than 1 month
  • October 6, 2024

For GERD "It worked, but I was dizzy almost all day, lightheaded, dry mouth, fatigue, heart palpitation, depressed eyes, a little blurry."

6 / 10
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  • Anonymous
  • Taken for less than 1 month
  • December 12, 2021

For GERD "Only been taking Nexium for 3 days. Oh my stomach, my head are in so much pain. I'm tired, but when I go to bed, I can’t sleep due to palpitations. I am not taking it anymore. It’s dangerous."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.