Comparing Loperamide vs Metoclopramide
| Loperamide | Metoclopramide |
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| Loperamide | Metoclopramide |
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Prescription and OTC
Loperamide effectively treats diarrhea in adults and children over the age of 2 years by slowing down the movement of the bowel. Children are especially sensitive to its effects, especially if they... View more |
Prescription only
Metoclopramide may be used short-term for the treatment of gastrointestinal reflux disease that is unresponsive to other medications or to treat diabetic stasis. Side effects may include sedation... View more |
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| More about Loperamide | More about Metoclopramide | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Loperamide has an average rating of 8.4 out of 10 from a total of 91 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 10% reported a negative effect. |
Metoclopramide has an average rating of 3.9 out of 10 from a total of 519 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 64% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Loperamide side effects |
View all Metoclopramide side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Loperamide prices |
View all Metoclopramide prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| A-D Anti-Diarrheal, Anti-Diarrheal, Diamode, Diar-Aid, Imodium, Imodium A-D, Kaopectate II, Neo-Diaral, Up and Up Anti-Diarrheal Solution View more | Gimoti, Maxolon, Reglan | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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10.8 hours |
8 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 352 drugs are known to interact with Loperamide:
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A total of 363 drugs are known to interact with Metoclopramide:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
December 30, 1980 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.