Skip to main content

Loperamide and Cramps: What Users Say

Brand names: Imodium, Imodium A-D, Anti-Diarrheal, Diamode, Up and Up Anti-Diarrheal Solution, Kaopectate II, Neo-Diaral, Diar-Aid A-D Anti-Diarrheal

Cramps: mentioned by 4 users (4.4%)

Based on user experiences from 91 Loperamide reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

constipation 6.6%
diarrhea 5.5%
cramps 4.4%
abdominal pain 3.3%
upset stomach 3.3%

Reviews for Loperamide

Commonly mentioned side effects
  • BIN...
  • Taken for 5 to 10 years
  • July 11, 2019

Loperamide for Diarrhea, Acute "After 5 years of stomach cramps and less than 1 minute of warning, I finally gave up on my PCP and started doing my own dietary analyses. My daughter worked at a fantastic bakery; she would bring home the 'day old' breads and bagels that didn't sell. Long story short, I overdosed on the best of the best at every meal and snack time. The culprit was GLUTEN; some days I was fine, then all of a sudden, 2 weeks' worth of cramps and runs. Then I gave up on bread, pizza, and pasta, which is a terrible thing for an Italian raised on the best foods. Breaded anything I now try to avoid: chicken, fish, fast foods. When the runs and cramps go away for weeks, I can risk a slice of pizza IF I take a gluten enzyme pill 20 minutes before I eat. Sometimes it works and sometimes it doesn't; then out comes the Imodium, 3 before bed and 2 in the AM. In a day or so, it's calmed down my IBS from whatever caused it."

8 / 10
Was this helpful?YesNo
27 Report
  • sis...
  • Taken for 6 months to 1 year
  • July 16, 2019

For Diarrhea, Chronic "I have Crohn's disease, and I take loperamide during flares so I don't have to be on the toilet all the time. It doesn't get rid of the other stuff like cramps, nausea, weight loss, or fatigue, but it does something for my diarrhea. It made my flares easier to manage at school and work, as I don't have to be racing to the bathroom all the time, then having to leave early as a result of my sickness. However, I had to rate it less than a 10 as it doesn't always work. The problem is I have malabsorption due to small intestinal inflammation, so sometimes the medicine might not work. Roughage will make it not work either. So, I can't just eat whatever I want while taking this. I still have to eat a bland low-roughage/residue diet."

8 / 10
Was this helpful?YesNo
17 Report
  • ann...
  • Taken for less than 1 month
  • August 1, 2016

Loperamide for Diarrhea "I was tapering off of both MS Contin and Percocet and developed diarrhea. I started taking Imodium and started itching and a rash. It did help the diarrhea, but I am one of the people that had a reaction to this medication, unfortunately. I also had cramping and sweating, as well as lightheadedness."

10 / 10
Was this helpful?YesNo
15 Report

Frequently asked questions

  • Fis...
  • Taken for less than 1 month
  • May 17, 2024

For Diarrhea, Chronic "I have spent the last year going to doctors. I had a contrast CT scan, a scope with biopsy. There is nothing physically wrong. I suffer from PTSD symptoms. The doctor said high adrenaline levels and little sleep are the issue. I cannot take bismuth or other drugs that coat your insides because I take diazepam. (That must be absorbed) Loperamide: I took 1 tablet (probably 2mg). It made things worse! I had the same bad cramps, but was constipated and could not use the toilet for 3 days. It did not help with the pain at all. It might have made it worse. Maybe I will try a lower dose. I've already had piles and a fissure. The cramps are nothing compared to a fissure. Which is what I am trying to avoid!"

6 / 10
Was this helpful?YesNo
0 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.