Skip to main content

Gabapentin Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Gabapentin Caplyta (lumateperone) Lybalvi (olanzapine / samidorphan)
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Gabapentin Caplyta (lumateperone) Lybalvi (olanzapine / samidorphan)
Prescription only

Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may... View more

Prescription only

Caplyta is an atypical antipsychotic that is used to treat adults with schizophrenia or depression associated with bipolar disorder. Sleepiness is the most common side effect and it should not be... View more

Prescription only

Prescribed for Bipolar Disorder, Schizophrenia. Lybalvi may also be used for purposes not listed in this medication guide.

More about Gabapentin More about Caplyta (lumateperone) More about Lybalvi (olanzapine / samidorphan)
Ratings & Reviews

Gabapentin has an average rating of 7.1 out of 10 from a total of 2574 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 21% reported a negative effect.

Caplyta has an average rating of 6.6 out of 10 from a total of 184 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 29% reported a negative effect.

Lybalvi has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 6% reported a negative effect.

View all 2574 reviews

View all 184 reviews

View all 16 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Gabapentin side effects

View all Caplyta side effects

View all Lybalvi side effects
Drug Class
Generic Availability

Lower cost generic

No lower cost generic approved

No lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 100 each
Strength 300 mg
Per unit* $0.24 - $0.33
Cost* $23.69 - $33.10

View all Gabapentin prices

Quantity 30 each
Strength 42 mg
Per unit* $61.18
Cost* $1,835.40

View all Caplyta prices

Quantity 30 tablet
Strength 5 mg-10 mg
Per unit* $58.95
Cost* $1,768.40

View all Lybalvi prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Forms
  • Oral capsule
  • Oral solution
  • Oral tablet
  • Oral tablet, extended release
  • Oral capsule
  • Oral tablet
Brand Names
Fanatrex, Gabarone, Gralise, Neurontin

N/A

N/A
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

6 hours

18 hours

54 hours (empirically)
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.
Drug Interactions

A total of 270 drugs are known to interact with Gabapentin:

  • 28 major drug interactions (148 brand and generic names)
  • 232 moderate drug interactions (1027 brand and generic names)
  • 10 minor drug interactions (52 brand and generic names)

A total of 604 drugs are known to interact with Caplyta:

  • 167 major drug interactions (620 brand and generic names)
  • 435 moderate drug interactions (1719 brand and generic names)
  • 2 minor drug interactions (5 brand and generic names)

A total of 700 drugs are known to interact with Lybalvi:

  • 66 major drug interactions (350 brand and generic names)
  • 626 moderate drug interactions (2356 brand and generic names)
  • 8 minor drug interactions (24 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness... View more
  • Grapefruit and grapefruit juice may increase the blood levels of lumateperone. In some cases, this... View more
  • Using lumateperone together with alcohol may increase side effects such as dizziness, drowsiness... View more
  • Alcohol can increase the nervous system side effects of OLANZapine such as dizziness, drowsiness... View more
Disease Interactions
First Approval Date

December 30, 1993

December 20, 2019

May 28, 2021
WADA Class View classifications

N/A

N/A

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Compare Drugs

To view a report comparing 3 (or more) medications, please sign in or create an account.

Create an account Sign In