Clozapine Alternatives Compared
| Clozapine | Fanapt (iloperidone) | Lybalvi (olanzapine / samidorphan) |
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| Clozapine | Fanapt (iloperidone) | Lybalvi (olanzapine / samidorphan) |
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Prescription only
Prescribed for Borderline Personality Disorder, Schizophrenia, Paranoid Disorder. Clozapine may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Bipolar Disorder, Schizophrenia, Psychosis. Fanapt may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Bipolar Disorder, Schizophrenia. Lybalvi may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Clozapine | More about Fanapt (iloperidone) | More about Lybalvi (olanzapine / samidorphan) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Clozapine has an average rating of 7.8 out of 10 from a total of 78 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 15% reported a negative effect. |
Fanapt has an average rating of 6.4 out of 10 from a total of 30 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 23% reported a negative effect. |
Lybalvi has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 6% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Clozapine side effects |
View all Fanapt side effects |
View all Lybalvi side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Clozapine prices |
View all Fanapt prices |
View all Lybalvi prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Clopine, Clozapine Synthon, Clozaril, Denzapine, Versacloz |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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10.3 hours |
37 hours |
54 hours (empirically) |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 945 drugs are known to interact with Clozapine:
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A total of 678 drugs are known to interact with Fanapt:
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A total of 702 drugs are known to interact with Lybalvi:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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September 26, 1989 |
May 06, 2009 |
May 28, 2021 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.