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Clarithromycin Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Clarithromycin Augmentin (amoxicillin / clavulanate) Amoxicillin
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Clarithromycin Augmentin (amoxicillin / clavulanate) Amoxicillin
Prescription only

Prescribed for Bronchitis, Bacterial Endocarditis Prevention, Dental Abscess, Follicular Lymphoma, Helicobacter Pylori Infection, Legionella Pneumonia, Middle Ear Infections, Mycobacterium... View more

Prescription only

Augmentin is a combination penicillin-type antibiotic that should be reserved for the treatment of infections caused by susceptible beta-lactamase-producing bacteria. Its use may be limited by... View more

Prescription only

Amoxicillin is a penicillin-type antibiotic that may be used to treat infections caused by susceptible bacteria. It is usually well tolerated, but a rash is a common side effect. Prescribed for... View more

More about Clarithromycin More about Augmentin (amoxicillin / clavulanate) More about Amoxicillin
Ratings & Reviews

Clarithromycin has an average rating of 5.4 out of 10 from a total of 851 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 35% reported a negative effect.

Augmentin has an average rating of 5.4 out of 10 from a total of 447 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 39% reported a negative effect.

Amoxicillin has an average rating of 6.4 out of 10 from a total of 366 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 30% reported a negative effect.

View all 851 reviews

View all 447 reviews

View all 366 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Clarithromycin side effects

View all Augmentin side effects

View all Amoxicillin side effects
Drug Class
Generic Availability

Lower cost generic

 Lower cost generic approved

Lower cost generic
Pricing and Coupons * Prices are without insurance
Quantity 30 each
Strength 500 mg
Per unit* $2.26
Cost* $67.75

View all Clarithromycin prices

Quantity 75 mL
Strength 125 mg-31.25 mg/5 mL
Per unit* $8.47
Cost* $635.25

View all Augmentin prices

Quantity 4 capsule
Strength 500 mg
Per unit* $2.61
Cost* $10.42

View all Amoxicillin prices

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Dosage Forms
  • Oral powder for reconstitution
  • Oral tablet
  • Oral tablet, extended release
  • Oral powder for reconstitution
  • Oral tablet
  • Oral capsule
  • Oral powder for reconstitution
  • Oral tablet
  • Oral tablet, chewable
  • Oral tablet, extended release
Brand Names
Biaxin XL Other amoxicillin / clavulanate brands include: Amoclan, Augmentin XR Amoxil, Apo-Amoxi
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

7 hours

1.7 hours

1.7 hours
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
B
Category B No proven risk in humans

See the full pregnancy warnings document.
B
Category B No proven risk in humans

See the full pregnancy warnings document.
Drug Interactions

A total of 712 drugs are known to interact with Clarithromycin:

  • 277 major drug interactions (985 brand and generic names)
  • 385 moderate drug interactions (1495 brand and generic names)
  • 50 minor drug interactions (167 brand and generic names)

A total of 90 drugs are known to interact with Augmentin:

  • 14 major drug interactions (39 brand and generic names)
  • 69 moderate drug interactions (321 brand and generic names)
  • 7 minor drug interactions (35 brand and generic names)

A total of 57 drugs are known to interact with Amoxicillin:

  • 7 major drug interactions (25 brand and generic names)
  • 43 moderate drug interactions (257 brand and generic names)
  • 7 minor drug interactions (35 brand and generic names)
Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
First Approval Date

October 31, 1991

N/A

January 18, 1974
WADA Class View classifications

N/A

N/A

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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