Chantix Alternatives Compared
| Chantix (varenicline) | Bupropion | Nicotine |
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| Chantix (varenicline) | Bupropion | Nicotine |
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Prescription only
Prescribed for Smoking Cessation. Chantix may also be used for purposes not listed in this medication guide. |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription and OTC
Prescribed for Smoking Cessation. Nicotine may also be used for purposes not listed in this medication guide. |
Related suggestions Smoking Cessation
Popular comparisons
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| More about Chantix (varenicline) | More about Bupropion | More about Nicotine | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Chantix has an average rating of 8.5 out of 10 from a total of 1199 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 9% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2898 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
Nicotine has an average rating of 7.6 out of 10 from a total of 202 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Chantix side effects |
View all Bupropion side effects |
View all Nicotine side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Chantix prices |
View all Bupropion prices |
View all Nicotine prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other varenicline brands include: Champix, Tyrvaya | Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Commit, Habitrol, Leader Nicotine Polacrilex, Nicoderm CQ, Nicorette, Nicorette DS, Nicotrol Inhaler, Nicotrol NS | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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24 hours |
30 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 8 drugs are known to interact with Chantix:
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A total of 527 drugs are known to interact with Bupropion:
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A total of 33 drugs are known to interact with Nicotine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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May 10, 2006 |
December 30, 1985 |
January 13, 1984 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.