Comparing Bupropion vs Chantix
| Bupropion | Chantix (varenicline) |
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| Bupropion | Chantix (varenicline) |
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Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Prescribed for Smoking Cessation. Chantix may also be used for purposes not listed in this medication guide. |
Related suggestions Smoking Cessation
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| More about Bupropion | More about Chantix (varenicline) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Bupropion has an average rating of 7.0 out of 10 from a total of 2900 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
Chantix has an average rating of 8.5 out of 10 from a total of 1199 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 9% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Bupropion side effects |
View all Chantix side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Bupropion prices |
View all Chantix prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Other varenicline brands include: Champix, Tyrvaya | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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30 hours |
24 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 527 drugs are known to interact with Bupropion:
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A total of 8 drugs are known to interact with Chantix:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 30, 1985 |
May 10, 2006 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.