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Chantix and Tiredness: What Users Say

Tiredness: mentioned by 57 users (4.8%)

Based on user experiences from 1,199 Chantix reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 21.5%
vivid dreams 20.0%
depression 8.1%
insomnia 5.0%
tiredness 4.8%
headaches 4.4%
irritability 3.7%
constipation 3.5%
upset stomach 3.3%
anxiety 2.8%

Reviews for Chantix

Commonly mentioned side effects
  • Dee...
  • Taken for 1 to 6 months
  • September 11, 2014

For Smoking Cessation "I love Chantix! It's amazing. The only side effects I had were a little nausea and some gas, but only if I didn't eat something or drink water with it. Very mild tiredness, nothing that a coffee or coke couldn't resolve quickly. Also, I experienced very vivid and wild dreams, almost realistic, but to be honest, I really enjoyed them. I have no desire to smoke whatsoever. It's the strangest and coolest thing in the world."

10 / 10
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  • Wan...
  • Taken for 1 to 6 months
  • December 20, 2018

For Smoking Cessation "I will be starting my 3rd month of Chantix in a few days. I’ve smoked a pack a day for 35 years. I’ve been diagnosed with stage 2 COPD. I’m down now to 5-6 cigarettes a day. I will smoke my very last cigarette tonight. However, the side effects as far as nausea have been very hard to tolerate. But I’ve learned from my doctor that I can take Zantac, and it works really well with the stomach upset. My dreams can be really vivid. I have some depression. I do find myself more tired and irritable, eating more and experiencing weight gain. The medication works, but you have to let it do its job, and you have to work with it. I’m stubborn, and I like smoking. I decided to try Chantix because I first read the reviews in here, and you all were my inspiration. I thank you for that, and I hope my quit date tomorrow, 12/20, is successful so that on Christmas, I may have the first few days of the rest of my life smoke-free to report to my kids. Thanks for listening, and thanks for your help."

10 / 10
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  • Fun...
  • Taken for less than 1 month
  • July 26, 2019

For Smoking Cessation "Chantix really works for sure. After using this for about 3 weeks - going on a month now, I have no cravings at all. I have been around smokers since I started Chantix, but the urge to smoke is no longer there. I tried to smoke in my second week on Chantix, and every time I put a cigarette in my mouth, I would gag and feel like throwing up. The only thing I hate about Chantix is it makes you really, really tired and always sleepy, so I have finished my 1st pack, and I am not taking Chantix anymore. I haven't had the urge to smoke at all. I just can't continue taking it anymore, mostly because of being tired and the dreams that I experienced while on Chantix. Otherwise, I'm glad I quit, and I feel so good physically and emotionally."

10 / 10
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35 Report

Frequently asked questions

  • DFi...
  • September 8, 2015

For Smoking Cessation "I started smoking at the age of 14. I'm now 28. I'm tired of feeling tired all the time and needing so much caffeine my chest hurts a lot. I started Chantix five days ago, and besides vivid dreams and feeling a little tired, it's been going really well. My quit date is Monday, September 14, 2015. My urge to smoke is becoming less and less, and I can't wait to get rid of this stupid, pointless habit! Good luck to everyone trying to quit! Remember why you're doing it!"

9 / 10
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  • Kjh...
  • November 17, 2019

For Smoking Cessation "I am currently on Cymbalta and was told it would not affect Champix. Day 1-3, I was very nauseous with a headache. Day 4, I was angry. Day 5 and 6, I was 'lost,' tired, and emotionally absent. Day 7 to 12, I went from emotionally absent to holding back tears daily. SEVERE sadness. Day 14, I was trying to fall asleep and heard someone say, 'Jesus. She is asleep. ZAP!' I live alone. Later that night, I had a complete mental breakdown. What I needed to do with my animals and if I should pack everything so no one would have to, all while crying hysterically. I was told by numerous people that I do not need to take this medication due to prior mental health issues. I told them, 'A few weeks of crazy is worth me not smoking.' After all, I have had issues for the past 30 years. I just KNEW I had been through and felt it all. I was wrong! If you have prior mental health issues, DO NOT TAKE IT!!!!! It elevates every issue by 100%."

5 / 10
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  • rep...
  • Taken for less than 1 month
  • April 27, 2014

For Smoking Cessation "This is my 3rd time taking Chantix. The 1st time I took it for 3 months and quit smoking for 3.5 years. I experienced the dreams but no other side effects. The 2nd time I took it for 1 month and quit smoking for 6 months. I still had the dreams but had nausea also. This time I've been on it for 4 weeks, smoke-free for 3 weeks. I'm having the dreams and had nausea for only the 2nd and 3rd week, but in the 2nd week, I started experiencing more side effects. I started feeling tired, lazy, bummed, and in a bit of a depressive state. In the 3rd week, I became paranoid and obsessive with racing thoughts. It's hard to focus, and now in the 4th week, I question if I'm hallucinating or dreaming. No thoughts of suicide. I quit taking it today and hope to stay smoke-free."

8 / 10
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37 Report
  • Ple...
  • Taken for less than 1 month
  • January 23, 2016

For Smoking Cessation "I'm 39 and have been a smoker for 20 years. I'll be 40 in March, and that was always a hard stop for me. I mean, if I didn't quit by 40, when would I ever? Quitting was tough for me. I would be very cranky, lethargic, pissed off, and would nic fit. I always wanted to stop, but in my heart of hearts, never 100%. This time I wanted to quit 100% and be done forever, and man, did Chantix come through. I smoked for 12 days while taking Chantix, and it's not that it made me stop. I noticed the gross cig smell more on my hands and shirts, but that was about it. The HUGE difference for me was that when I did stop, my mood was basically the same. What a miracle! No nic fitting, no more tired, just me feeling great and empowered."

10 / 10
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29 Report
  • lig...
  • October 26, 2007

For Smoking Cessation "I am a 20-year, one-pack-a-day smoker. I am on my 3rd day of 0.5 mg of Chantix. I'm concerned about bumping up to the 1.0 mg dose I'm supposed to take tomorrow because I'm already feeling tired, way angry, depressed, disconnected, accompanied by strange thoughts. I am normally a very happy person. I'm 103 lbs. I think this drug should be dosed out according to weight. I can't believe I need the same dose that a 300 lb man would need. I think this is too much for me. I'm nervous about side effects."

4 / 10
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50 Report
  • cha...
  • December 4, 2015

For Smoking Cessation "I used Chantix twice before this, and quit every time. Hubby and I were on a cruise, just days shy of 4 years quit, and well, he had a bright idea to buy cigarettes at the store on the ship duty-free, because it was so cheap. We would quit when we got off the ship. After a few no, no, no's, well, 15 months later I just started taking Chantix at Thanksgiving 2015, and here it is 8 days later. Every cigarette I smoke tastes horrible. I went from a pack a day to 3 per day. In fact, my pack is empty and I am not buying another, so today is my quit day. I have had some nausea at times, lasting a few minutes, and very interesting vivid dreams, not scary or bad, but I feel the dreams disrupt my sleep and make me tired during the day."

10 / 10
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27 Report
  • ali...
  • January 11, 2008

For Smoking Cessation "I have not smoked in 4 months, and I owe it all to Chantix. I had shortness of breath, severe headaches, felt very lethargic, absent-minded, and depressed. I ended up in the emergency room. I am fine now, but I have not taken it for 2 months. And the best is I am a non-smoker! They say it will take a few months before I feel myself again. I have no desire to smoke."

9 / 10
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43 Report
  • Grn...
  • Taken for less than 1 month
  • December 4, 2013

For Smoking Cessation "38-year-old female who smoked for 21 years. I smoked the first week on Chantix, and it tasted nasty. Before Chantix, I loved the feeling of inhaling the smoke. After starting Chantix, and because it tasted nasty, that feeling went away. I only took Chantix for two weeks. I didn't mind the weird dreams, but I could not stand the flu-like symptoms. My body ached, I was always tired, and shortly after I took the pill, I would get a bad upset stomach. After all of that, I would do it again in a heartbeat! I love not being a smoker. No more smelly clothes. Smoked a pack a day, so saving money there. Prior to Chantix, I tried electronic cigarettes to quit smoking, it didn't work. Now it keeps my hands busy. Three months, no smoke. YOU HAVE TO WANT TO QUIT!"

10 / 10
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26 Report
  • Aug...
  • Taken for 1 to 6 months
  • September 2, 2013

For Smoking Cessation "I started taking Chantix on August 1. I read some of the reviews and thought, wow, that sounds like it might work for me. I have been smoking a pack a day for 20 years. I started when I was 13. I had no side effects, except it made me a little tired the first week. I wasn't sure how it would affect me, so I took the morning pill at night during week one. No upset stomach, except one day when I didn't eat before taking the pill. No bad dreams, but they were very vivid and pleasurable. I smoked through the first 9 days. My last cigarette was on August 9. I took a drag of a cigarette on August 10, but it tasted terrible, even after a glass of wine! Today is September 2, and I am still smoke-free! Yay! Chantix is amazing!"

10 / 10
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28 Report
  • Str...
  • Taken for less than 1 month
  • July 2, 2018

For Smoking Cessation "I've smoked now for 24 years and was up to 1 pack a day for about a year. I started Chantix 1 week ago, and I continued to smoke in decreased amounts. However, on day number 3, every time I smoked, I felt nauseous, very weak, and got a very bad headache regardless of eating before taking it. I'm now on week number 2, and for the first time as of 7-2-18, I've only smoked once! I'm so proud of myself because by now I would've smoked at least 7 cigarettes! I know being smoke-free is attainable for me, but I do get very strong cravings, especially in the morning, but it is much easier in the evenings to fight the cravings. Thus far, the side effects I have experienced are constipation, increased appetite, nausea, tiredness, and vivid dreams, but good ones! So far, I would say Chantix is helping me battle the urge to smoke, and I do see a smoke-free road ahead of me!"

8 / 10
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17 Report
  • KT ...
  • Taken for less than 1 month
  • September 10, 2016

For Smoking Cessation "I'm happy to see that Chantix helped people. We all know cigarettes are not healthy, tax your breathing, make you a social pariah, etc. And then there's the ridiculous cost, which is why I wanted to stop; for all the reasons listed above. I knew from the commercial that this could make me depressed and suicidal. I thought it was the common disclaimer to avoid liability if I decided to stop smoking but jump off a bridge, which is where I was pretty quickly into it. I felt like a zombie, was ridiculously tired. No matter how much sleep I got, I was tired. And sad. Cigarettes lost their appeal, as did everything else. I was/am extremely congested, sad, 'lost,' hopeless. My teeth hurt. I also had strange smells. Good news: stopping abruptly is OK."

1 / 10
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23 Report
  • pin...
  • June 17, 2007

For Smoking Cessation "My husband has been taking the Chantix trying to quit, and I came here because he has been experiencing depression, irritability, and lethargy. He has seemed more punchy about needing to eat (maybe the hunger?). I thought maybe the medication could be causing the depression, but that wasn't listed as a symptom."

5 / 10
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37 Report
  • lud...
  • December 14, 2007

For Smoking Cessation "I am on my second month of Chantix and am smoke-free. The craving for a cigarette is still occasional. I have experienced mild nausea for about 30 minutes after taking pills in the morning and at night. One thing that concerns me is the lethargy. I just don't want to do anything at all, which is not like me at all. My husband and I discussed this, and we have agreed that I will at least finish the second month of the pill. I think the side effects are worth not smoking. Good luck to everyone!!!!"

8 / 10
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33 Report
  • Wis...
  • September 19, 2007

For Smoking Cessation "I have been a smoker for most of my life. I was told by my daughter (a nurse) originally about Chantix. Many of her co-workers were doing great with it. I too have had a few side effects. I have the dreams and sometimes feel slightly lethargic. I did have a queasy stomach for a few days when I started taking it, but that has subsided. Overall, I think that it has helped tremendously. 39 days without a "puff". Hang in there, all you good people."

9 / 10
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32 Report
  • Iam...
  • November 7, 2015

For Smoking Cessation "So funny how some of the responses say Chantix didn't work. I have smoked for the last 13 years, around a pack or more a day. I have tried to quit on many occasions but was not successful. Like many new endeavors, losing weight, etc., unless you truly want to quit, nothing will work for you, please do not blame the medicine or program! I took Chantix for a month, had some of the symptoms like crazy dreams, it made me a little tired and most certainly take with food. I noticed the first week not smoking as many cigarettes. I purposely stepped down the numbers I smoked every day, by the 3rd week, I laid them down! I had a few trigger moments but got through them and have never looked back. One day at a time and truly wanting to be free is the way."

9 / 10
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19 Report
  • Lig...
  • February 4, 2013

For Smoking Cessation "Chantix is phenomenal! I started smoking just over 10 years ago as an occasional smoker, but with some time, I was totally committed to taking years of my life, especially when I would add an alcoholic beverage to the mix. There was nothing tastier than a cigarette. I started taking Chantix, and during the first week, I was still smoking, not because it was enjoyable, but mostly because of habit. They tasted horrible, so I would take 2 puffs and throw it out. I stopped taking Chantix and was able to remain smoke-free. Like some of the other comments, the dreams are intense, very vivid, very weird, and I actually remember them when I wake up. Another downside is that I am tired, but it's worth it! Quit while you're ahead."

10 / 10
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24 Report
  • Smo...
  • April 29, 2015

For Smoking Cessation "I started smoking the second time around for about 7 years now. I am 43 years old with high blood pressure. Cholesterol is fine. So I talked with my doctor, and I am on week two, day three of taking Chantix. I have experienced bouts of nausea. I have been reading the reviews, and I am going to take it with milk. I used to smoke at least 10 cigs a day. Today I only had one, tried smoking another one. Nah, it was awful! I'm glad because I don't want to stroke out from high blood pressure. I now have to take blood pressure medicine. I've only had one crazy dream. I do feel tired at times. Cried a few times, but I'm gonna tough it out! Thank you for your reviews and suggestions. I'll keep you posted. Be blessed, all!"

8 / 10
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18 Report
  • Anonymous
  • Taken for less than 1 month
  • February 20, 2013

For Smoking Cessation "I've been on Chantix for 2 weeks. I have reduced the amount I smoke, and they smell awful, and I can't finish the smoking. I also live with smokers who have decided not to quit and refuse to honor my request to smoke outdoors, making it even more difficult to quit. I am a 2 to 3 pk a day, sometimes 4 pks a day smoker. I am down to less than 2 pks a day. I do have issues with my chest feeling very heavy and shortness of breath since taking Chantix. I have developed vertigo and upper respiratory infection since using Chantix. The cravings aren't as intense, and I don't feel any anger. I do have very vivid dreams (not nightmares). I am also very itchy all over and get chills and hot flashes since taking Chantix and am very tired all the time."

6 / 10
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30 Report
  • Cou...
  • May 31, 2018

For Smoking Cessation "I have been a smoker for 10 years. I am at the end of my 4th week on Chantix and have been nicotine-free for 6 days! I still have the urge to smoke when I initially get in my car to go somewhere or after I eat, but the craving subsides surprisingly easily and rather quickly. I take one tablet in the morning and at night (be sure to eat and let your food settle before you take the morning dose to prevent the nausea!). I do feel more tired than usual and cranky during week 2, but not unmanageable. I've been having vivid dreams, but good ones! I'm dreaming in color and wanting to go back to sleep to find out what happens next! I've tried everything before Chantix. I haven't had any depression episodes, though it is a known side effect. No medicine is a one size fits all, so if you do take it or don't, understand that the reactions aren't the same for everyone. I would suggest if you try it to take it exactly as prescribed and visit your doctor regularly to monitor how it affects you."

9 / 10
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13 Report
  • Gra...
  • October 19, 2013

For Smoking Cessation "3 1/2 years ago, I decided to take Chantix to quit smoking. For me, Chantix was a miracle. I have had no desire to smoke since I quit. I feel so much better and breathe much better. I smoked a pack per day for over 20 years. I was feeling short of breath and exhausted all of the time. Not anymore. Thank you, Chantix."

10 / 10
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19 Report
  • H92...
  • Taken for less than 1 month
  • January 29, 2013

For Smoking Cessation "I'm on Day 8 of Chantix. I have smoked for twenty years and tried several other methods without success. My best friend is also taking it at the same time. The dreams are vivid. I'm very tired. I've also had headaches, which are not typical for me. I'm light sensitive and so dizzy that I feel unsafe driving or working at times. However, I've continued to take one pill a day instead of the two. I'm now on 1 mg. I have noticed less cravings. I'm so miserable that I'm gonna stop smoking just so I can quit this medication. Oh, and I forget, depressed. Wish you all luck!"

5 / 10
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21 Report
  • RJS...
  • September 24, 2007

For Smoking Cessation "My husband began Chantix 3 months ago. At first, he only had the physical symptoms of nausea, gas, shortness of breath, insomnia, and active dreaming. He was somewhat lethargic and hungry, eating all the time. However, by the end of the 3rd month, he was extremely irritable, unable to focus on any one task, very negative, somewhat irrational, angry, every day was a bad mood. I would NOT recommend Chantix. I don't really think the Chantix helped him quit. He quit on his own."

2 / 10
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43 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.