Nicotine Interactions
There are 33 drugs known to interact with nicotine, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 22 are moderate, and 11 are minor.
- View all 33 medications that may interact with nicotine
- View nicotine alcohol/food interactions (1)
- View nicotine disease interactions (8)
Most frequently checked interactions
View interaction reports for nicotine and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Paracetamol (acetaminophen)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Spiriva (tiotropium)
- Symbicort (budesonide / formoterol)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Nicotine alcohol/food interactions
There is 1 alcohol/food interaction with nicotine.
Nicotine disease interactions
There are 8 disease interactions with nicotine which include:
Report options
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More about nicotine
- nicotine consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (202)
- Drug images
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Support group
- Drug class: smoking cessation agents
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
