Trintellix User Reviews & Ratings (Page 4)

• cal...
• February 23, 2020

For Depression "Trintellix started working by the end of the second week and continues to. I am happier than I have ever been and so impressed that Trintellix was able to get me through the incredibly difficult last two months, e.g., changed jobs, had a project with an impossible deadline, the holidays, etc. I'm on 10mg daily. Side effect-wise, I have some sexual dysfunction (loss of libido, difficult to achieve orgasm), but right now, it seems worth it to feel this good. I've also lost weight. A new wrinkle as of 2 weeks ago is tinnitus. I only notice it when it's totally quiet, which hasn't made sleeping the best, so I take Trazodone to help with that, which works great. After two months, I'm still feeling great on the Trintellix, but the side effects aren't dissipating, and I'm wondering how long I will be able to deal with them. Definitely not forever. Will update if things change."

• Cat...
• Taken for 1 to 6 months
• July 30, 2019

For Depression "First and foremost, one thing I have learned more than anything is that a medication is not a 'cure all'. We need to do the work too with hobbies, therapy, self-care, etc. But without this medication, I may have not been able to do that. I had frighteningly severe social anxiety and couldn’t leave my house, which led to depression and fed that cycle. I was honestly suicidal. Being fed up with living in misery and having tried literally all antidepressants and anti-anxiety medications on the market before turning 30 years old, this one finally let me breathe. I haven’t gained weight (what most people fear), I’ve actually LOST weight because I’m motivated to work out and eat well. I had a little constipation at first, but drinking enough water helped that. My life is... a complete 180 from where I was two months ago. The only downside is that insurance is so awful to deal with in order to get on this!"

• CLH...
• Taken for less than 1 month
• October 6, 2019

For Depression "I've battled anxiety and depression since I was a teenager. I was 21 when I first started taking an antidepressant. I'm 34 now and have taken about 3 different antidepressants. Zoloft, Paxil, and Effexor XR. Effexor worked for several years but I had some side effects such as constantly feeling groggy and tired. It helped the anxiety, but not the depression. I asked about Trintellix and was then prescribed it. I could tell a major difference with just 3 days of taking the medication! So far no side effects, I sleep way less (could sleep a total of 12-15 hours), feel much happier, more willing to do basic chores, errands, work, and the anxiety is suppressed. I just want to say that so far this medication has been life-changing for me. Antidepressants are always based on personally trialing them. You have to basically try several to see which one works for you. I love this medicine!"

• qua...
• Taken for 1 to 6 months
• February 18, 2025

For Major Depressive Disorder "I've been scared of taking antidepressants all my life. Scared of it making me feel numb. It ruining my creativity. Trintellix is the best thing that has ever happened to me. I still feel myself, I can still cry, I can still feel excited. But for the first time in more than 10 years, I can live my life without suffering every moment of it."

• She...
• October 12, 2015

For Depression "I have literally been on every antidepressant made over the last six years trying to get my depression and anxiety under control. Every single time I had severe adverse side effects, except with Lexapro which worked amazing for about six months. I had given up on medication, but my symptoms persisted and I hit a low and knew I had to do something. I am hypersensitive to medication, and because of my past side effect issues, my new PCP gave me samples of Trintellix, starting at 5 milligrams. I immediately felt better and had zero side effects, so when I had a follow-up visit a week later, she bumped it up to 10 milligrams. Two weeks on the new dose and I feel amazing. I feel like me again. Best med I've used!"

• Sco...
• Taken for less than 1 month
• April 10, 2019

For Depression "Trintellix is great stuff, and glad I've finally found the drug that suits me. Been on Trintellix for nearly 2 weeks and my mood is so much better. Head is clear and I can get on with my day with no problems. I did have nausea for about 3 days but it's not that bad. No effect on sex drive or performance. It's worked for me. I hope it works for you"

• Pau...
• Taken for 1 to 6 months
• February 11, 2019

For Depression "Reading so many other people having bad issues with this drug has me somewhat concerned. But at least for me so far, I am thrilled with Trintellix! It is not cheap but my insurance pays a good deal. And I have a good job. So I am completely willing to pay. I was taking Viibryd. But it stopped being effective. I have had no nausea or stomach issues. I have only been on it about a month. It was working much better than Viibryd within a week. I am much less irritable. No sexual side effects. I take this for both depression and OCD. It is not labeled for OCD. But antidepressants typically also work for OCD. And it does for me."

• mid...
• Taken for 1 to 6 months
• April 16, 2015

For Depression "This medicine saved me! I have always been a very happy and successful person. Depression and anxiety were not a part of my life until I hit 43. So I went to doctors and they had me try a few other meds, Zoloft, etc. I didn't see any positive effect from them, just the problems...lack of sleep, night sweats, sexual problems, etc. Things were getting worse. Then, my doctor put me on this medication and everything changed. First, I started getting headaches for a few days. That went away by the end of the first week. I started on 5mg and then went to 10mg after a week. By the end of week two, my panic attacks were GONE! I still 'think' about my problems, but don't obsess about them. This is a GOOD medicine!"

• Ave...
• April 4, 2019

For Depression "Positives: Trintellix helped me manage my anxiety and depression for a time. I had a few good days where I felt almost normal. I was able to continue working full time and focus enough to 'appear' normal. Negatives: After 5 weeks on 10 mg, I increased to 20 mg for a week and that was too much. I ended up in the ER, and they recommended to stop the medication (after 6 weeks total). I’ve been off this med for 4 weeks and waiting for an appointment in a few days to discuss another med. I’m sleeping a lot better now than before starting Trintellix, but I still have issues with depression and anxiety that affect my daily life. I used Zoloft 50 mg in the past for PPA, but it wasn’t effective the 2nd time I tried it. Going to try another med, not ever going to give up. If you have read this far and are looking for encouragement, know that there is a med that will work for you and you will get better. There is hope, even if it doesn’t 'feel' like it today."

• Ber...
• April 6, 2019

For Depression "I am not one to tattle on drugs or make blanket statements, but I had a horrible experience on Trintellix. Sobbing uncontrollably and wanted to kill myself. Went into the darkest of places on this drug. Immediate relief when I came off it. I am sure it works for some people. Unfortunately, I had a terrifying experience with it."

• Cat...
• May 16, 2015

For Depression "I've been severely depressed for 10 years including 2 hospital stays. My psychiatrist is excellent and suggested Trintellix after I've been on Cymbalta for 2 years. Already feeling much less sleepy, more able to complete tasks, not moping around all day, and I have hope. The only side effect is skin itching that I can't seem to stop, but other than that, I'm very happy. If you've given up on life, the future, and any chance of recovery, give it a try."

• Fee...
• April 26, 2017

For Depression "I have been on many antidepressants and they all make me want to snack and overeat. I gained a lot of weight on all of the other antidepressants. I was so tired of gaining weight. About a year ago, I started taking Trintellix and I am no longer craving snacks all day. My depression was marked by feelings of irritability and lots of crying. I feel 100% better. I think that this medication has worked better than any others I've tried. So relieved."

• Ste...
• Taken for 1 to 6 months
• November 11, 2018

For Depression "I am a 51-year-old male and have tried everything too. I started Trintellix a month ago with 5mg. I did experience some stomach issues for one day. After a week, I went up to 10mg. After another week, with my doctor’s OK, I went up to 15mg. No side effects. I am now on 20mg and am feeling better than I have felt in a long time. Sleeping well and zero depression. All medication is different for different people but I am truly happy on Trintellix and keep working with your doctor to find a way out of depression. There is something that will work for you."

• bob...
• Taken for less than 1 month
• December 27, 2020

For Depression "Started on 5 mg daily for two weeks after taking Wellbutrin 300 XL and duloxetine 20 daily, which caused severe tinnitus, jaw pain, and bruxism, fracturing three teeth. Initially got some minor nausea but the jaw pain lessened and totally disappeared. I felt good with some minor anxiety. After 2 weeks, increased to 10 mg daily. Again, the nausea returned but was gone on day four. I do have some jaw tension now but not too bad. I feel more alive. Doing tasks is easier. My spouse says I look more relaxed. On a scale of 1 to 10, I give myself a 6. Laughter comes naturally now. Sad movies give me a lump in the throat and tears. Thank God for Trintellix as it is returning my life to me."

• Yay...
• Taken for 6 months to 1 year
• September 26, 2023

For Major Depressive Disorder "I tried different medications for around a year and a half, including most of the SSRI family, and some anticonvulsants and antipsychotics off-label. I have GAD and MDD. Trintellix was the only thing to finally work for me. It was a life saver. No side effects to speak of. I take 20mg. Manufacturer's coupon brings it down to only about $35 a month. So grateful I found this."

• Aud...
• June 10, 2015

For Depression "I've been battling MDD for about ten years now, and I've been on and off many different medications. My biggest complaint with most of them was the fatigue. I'm only 24, but while I was on this medication, it was hard for me to keep up with my friends who were similar ages. I was always tired, always taking naps, and still going to bed early. With Trintellix, the fatigue is GONE! It's easier for me to wake up, I can do more during the day without wanting to take a nap, and having more energy has given me the opportunity to start exercising again. I do have a bit of stomach upset while taking it, but it is mild and, frankly, a small price to pay when considering all the good Trintellix does for me."

• Wor...
• Taken for less than 1 month
• March 12, 2024

For Major Depressive Disorder "I have been on 5 mg Trintellix for 1 month. The only side effects I've had are somewhat dry mouth sometimes, and not being able to sleep as well as I used to. Other than those 2 things, it has worked great for me! For the first 1-2 weeks, I did continue to have some bad days, but starting about week 3, the bad times became less extreme and have continued to do so. My insurance wouldn't pay for it, so I applied for assistance on the manufacturer's website, and received it for free."

• Ron...
• Taken for 1 to 2 years
• January 21, 2025

For Major Depressive Disorder "It's the only thing I have found to work. Unfortunately, I can't afford it anymore. I am on disability and Medicare, on a budget, and was paying 100 a month for Trintellix. Now this year, there is a deductible on it for 340, and after that, 100 a month! If I become so depressed, something happens, you will know why! Just like a drug dealer teasing you with their drugs and then going up on it!"

• RJa...
• Taken for 1 to 6 months
• May 11, 2019

For Depression "I have suffered from depression off and on since my teenage years. I've tried literally dozens of psych meds over the last 30 years and had no relief. I started on Trintellix with Wellbutrin XL, and I feel great. I started to see results within a week. I have now been on it for three months, and still very happy with it. My mood is great, I have energy and motivation. For me, it's been a miracle drug."

• Hek...
• Taken for 1 to 6 months
• January 22, 2017

For Depression "Taking it since one month because of a reactive depression for over a year. I have never taken anti-depressants before and kept refusing although my psychologist urged me to for several months. When the depression kept getting darker: no energy, sad, bad insomnia and constant thoughts of suicide (which my psychologist didn't know) I decided to take the advice to start on Trintellix (was either that or kill myself). The first 4 days I was so tired I spent most of the time in bed. Then I just started to feel better and better. High energy level, creative, not sad, no mood swings, slept great at night and best of all the suicidal thoughts just disappeared. I started and stayed on 5 mg. No side effects at all, working night shift no problem!"

• eli...
• August 9, 2016

For Major Depressive Disorder "This medication is a game changer. I've been on 20 mg once per day (at night works best for me) for about 5 months. It is by far the best medication I have tried. Initially started on 10 mg, and raised my dose 2 months in. Pros: Overall heightened mood, more energy, ability to feel array of emotions, no sexual dysfunction (many antidepressants are famous for causing this), increases ability to enjoy activities I used to love. Neutral: does not treat my anxiety very well alone. Cons: nausea when starting the medication and increasing dose, more expensive than traditional antidepressants. Overall, I love this medication. I will definitely continue on it. I have seen a big improvement since trying Trintellix."

• So...
• Taken for less than 1 month
• October 21, 2014

For Depression "I am a 46-year-old female with generalized anxiety disorder and depression. I tried Zoloft because it helped three of my family members. Zoloft made me miserable! I ended up in the psych ward with severe anxiety, depression, and nausea. My doctor took me off of Zoloft and put me on 10 mg of Trintellix, and I noticed a change pretty quickly. He also had me on 0.5 mg of Klonopin twice a day. My nausea virtually disappeared, and my anxiety/depression improved significantly. I had some lightheadedness and itchiness on and off, but eventually, that subsided. I've reduced my Klonopin to one pill a day. I'm still going to therapy and trying to exercise and read my Bible, which helps, but the medication has been a godsend so far. I highly recommend it. The only thing is it is expensive."

• Mid...
• March 15, 2017

For Depression "One month on 5mg of Trintellix. I was on Zoloft for 3 years and was a zombie. It is like a veil has been lifted. I have energy like I did when I was in my 20s. I also can see I am clearly surrounded by critical, condescending people. I never was able to give much thought to their behavior while on Zoloft. I am experiencing a euphoric feeling that was absent prior to Trintellix."

• MP2...
• April 3, 2014

For Depression "I've tried so many antidepressants but this one has been the best. I was on 10mg for a month and just had my dosage increased to 20 mg, two days ago. I do feel sick, nausea and a little disoriented but those are bearable side effects to me. I have had energy, better concentration but the biggest thing I love about this antidepressant is that I have my sex drive back. My libido wasn't affected like it has been in the past with other meds, I've actually had increased sex drive. So far I feel 'okay' but hopefully since 20mg is the therapeutic dose, that I feel more 'content' or 'happy' with my life soon."

• Aun...
• May 15, 2015

For Depression "I was on Lexapro for about 2 years until it stopped working. Prior to that, over the last 25 years, I was always on an antidepressant. You name it, I've tried it. What the antidepressants did for me was just take away the severe irritability that I had. I was really at a low point when my doctor asked me to try Trintellix. I had no desire to do anything. I felt no joy. I had been taking 40 mg of Lexapro a day. Doc said I didn't have to wean off it. He said I could just switch, starting the next day, and I did. I started on 5mg for the first 2 wks then increased to 10mg. It's only been 4 wks that I have been on it and my nausea has gotten better. I have a clarity in thinking that I didn't have before. I feel joy now. I am staying on it. Also, no sexual problems on it. Got hope!"