Tirzepatide and Burping: What Users Say

• 60y...
• March 22, 2023

For Weight Loss (Obesity/Overweight) "I have been on Mounjaro since Jan. 2023. I have lost 20 pounds. I need to lose 20 more. Side effects: burping, stomach upset, constipation, flu-like body aches, mildly depressed feeling, and fatigue. Not every day, not every symptom every day, and not all day. It comes and goes. I will continue but do wonder how it’s gonna go long term. I’m just sick of being fat."

• SdS...
• Taken for 1 to 2 years
• February 13, 2025

For Weight Loss (Obesity/Overweight) "I have been on Zepbound for almost a full year. I lost weight quickly: 90 pounds. I was at my goal in 6 months. I had to go back 2 doses to maintain and stop losing weight. The nausea has not stopped. It’s better than in the beginning, but I still get it every time for 1 or 2 days after a shot. The diarrhea is terrible. It has never stopped. I get it on day 2, and it is uncontrollable. It’s been almost a year, so I would think some of these side effects would have stopped, but they haven’t. I also get sulfur burps for a day or 2 after a shot. I’m at the point where I might have to stop taking it due to the side effects. I love the weight loss, and I sure don’t want to gain it back, though."

• Krg...
• Taken for less than 1 month
• February 4, 2025

"Follow Up: I am currently on day 11 of Zepbound 2.5 mg. As of this morning, I have lost 11.73 lbs. Daily, I documented how I felt and symptoms. The first 24 hours of injection #1, I had extreme fatigue, normal appetite, and a whole lot of belching. Day 2, belching, less hungry, no other symptoms. Day 3, I had no appetite, no other symptoms. Day 4, less than normal appetite, no other symptoms . Days 3 and 4 have just been repetitive. I have had no negative side effects, BUT I also have made sure to eat high-protein foods for every meal, even on the days I had no appetite, nothing greasy (thinking about it turns my stomach), no high-sugar foods. As of today, I’d say; if you work with the medication, the medication will work with you. Update you in a couple of weeks."

• Suz...
• Taken for 1 to 6 months
• December 2, 2024

For Weight Loss (Obesity/Overweight) "I started on Zepbound Sept 3rd, 2024. The sulfur burps started but subsided after a day or so. Each time I give the shot, I get a little of this. I’ve stayed at .05 mL because I have a bit of a sour stomach, so don’t want to have worse, and I like my slow weight loss (14 lbs) as of 11/30/24. I heard if one loses too fast, it results in saggy skin. I had a problem with the protein powder, so discontinued, but realize making sure to get enough protein is crucial. My positive effect I’d like to report is I’m no longer lactose intolerant! So exciting! I can eat whatever I want without fear of the usual aftereffects. I didn’t need to lose much weight, but my added concern is that I have sleep apnea (couldn’t tolerate C-PAP). I’ll report back when I make a recording to see if it’s been eliminated. I only live with dogs, and they refuse to tell me if I’m still snoring or not."

• SMP...
• Taken for 6 months to 1 year
• February 5, 2025

For Weight Loss (Obesity/Overweight) "I’ve lost 43 lbs in the last 9 months. I experienced some mild hair loss (but started this in menopause, so that contributed to hair loss as well), increased heart rate, although mine was low to start, some burping, and tiredness. The worst side effect for me is the diarrhea. I have it starting about 24-48 hrs after injection. It lasts on and off for about 3 days. Overall, these side effects have been mild and manageable. The weight loss has been life-changing!!"

• Kay...
• Taken for 1 to 6 months
• January 10, 2025

For Weight Loss (Obesity/Overweight) "I started taking Mounjaro 2.5 mg on September 6th, weighing in at 128 kilos. I'm now on my 7th shot of 10 mg (as I stayed on 10 mg for another month over Christmas) and I weigh 106 kilos in January. This is without changing my lifestyle of exercise or food. I eat smaller portions and don't think about food half as much as I used to. It's been great up until my 6th shot of 10 mg. I would experience mild side effects of nausea, vomiting, diarrhea, sulfur burps. These tended to be spread across the board as well though, never all at the same time, and it was manageable. However, my 6th dose I felt instantly! I was nauseous for 3 days straight, vomiting, diarrhea, sulfur burps, tired, the list is endless. I was so worn out by the nausea, I couldn't sleep, eat, or drink. I took myself to the walk-in center at the hospital where they referred me straight to A&E for having a resting heart rate of 128 bpm. I was put on an IV drip, bloods taken. I felt awful and still do! Going to go back to 7.5 mg."

• Kat...
• Taken for 1 to 6 months
• January 20, 2023

For Type 2 Diabetes "I started Mounjaro to help control my blood sugar. I had tried Ozempic and Trulicity and could not tolerate the nausea, sulfur burps, and stomach issues. Mounjaro has been life-changing. No bad side effects. I’m not hungry, I don’t have cravings, I’m losing weight steadily, and sweet desserts taste too sweet. Many people say they’ve had bad side effects with it. I say try it as it may work for you. Just like I couldn’t use other meds that other people love. For me, it has been life-altering."

• Pen...
• Taken for less than 1 month
• September 23, 2022

For Type 2 Diabetes "I started taking Mounjaro on 9/1. This resulted in the very worst month of my life. WEEK ONE - Super Nauseous, indigestion, stomach pain for 3-4 days of the first week. My appetite went from a 10 to a 2 (which was good). WEEK TWO - I had diarrhea for 3-4 days, along with sulfur belches, nausea, stomach pain. I ended up having to take sick days and go get an IV bag to recover from the dehydration. WEEK THREE - World-class nausea and vomiting. 3 days of vomiting so hard that I ruptured my esophagus. The entire month, if I was not having diarrhea, I was VERY constipated. I lost 9 lbs in one month, but I don't know if it was because I could barely eat due to the sickness. PASS!!"

• Anonymous
• Taken for 1 to 6 months
• March 29, 2023

For Weight Loss (Obesity/Overweight) "I'm on month three. My doctor thinks I might be too sensitive to it and may have to stop soon. Extreme nausea, occasional vomiting, and sulfur burps followed by diarrhea, weakness, and lethargy. The pros: in three months, I've gone from 262 lbs to 239 lbs."

• Mim...
• Taken for 1 to 6 months
• December 29, 2022

For Type 2 Diabetes "I'm type 2 diabetic and was on Ozempic for quite some time and having difficulty getting my medication. My doctor changed me to Mounjaro for my diabetes thinking I would be able to get my meds. I started on the 5 mg since I had been on Ozempic. My side effects were typical slight nausea. I was trying to get my second month filled and the issues started with availability AGAIN. The 5 mg and 7.5 mg were on backorder. He increased my dose to 10 mg. I have experienced sulfur burps, but that is about it. I have not seen much weight loss, but then again I'm more concerned about my diabetes. Shame on the drug companies for dangling a medication that works to lower A1C and cholesterol and choosing to utilize it for weight loss where the insurance won't cover it. I'm not using this medication for vanity, it's for my chronic disease."

• Nop...
• Taken for less than 1 month
• September 15, 2022

For Type 2 Diabetes "Holy side effects. First, if you eat when you take it, it just sits in your stomach and you’ll be burping it for 12 hours. The headache is insane. Starts immediately. Then you are hit with 3 days of nausea, fatigue, and just overall fatigue. Just when you start to feel better, cue the insane heartburn! It took me 5 days to feel normal again. I’ll pass on this even though I lost 5 pounds the first week."

• Nan...
• Taken for less than 1 month
• January 30, 2025

For Weight Loss (Obesity/Overweight) "I have just started on the 2.5 mg dose. This is the end of my second week. I’m not experiencing any side effects except belching. I’m really looking forward to my weight loss and feel confident that with some walking daily and use of light weights I will reach my goal. I’m not overdoing the exercise, as when I do, I regrettably always quit. I’m paying for this out of pocket, so this is also a great motivator for me (get my money’s worth!) Using the injection is no problem, and I’m also looking forward to no more snoring (sleep apnea), which is a bonus as I didn’t know about that until I started taking it. This will please my husband! I’m purchasing it through Eli Lilly and my dr. sends them my script, I pay them monthly, and they send it to me via mail. I’m hoping Medicare may cover this in the future, as it’s been in the news it will if you have sleep apnea."

• Anonymous
• Taken for 1 to 6 months
• January 19, 2023

For Type 2 Diabetes "I tried Ozempic for 9 weeks and thought I was going to die, so they switched me to Mounjaro. The 1st 2 weeks were okay, I just didn't have an appetite, but week 3 hit me just like Ozempic did. Total exhaustion. I've lost 5 lbs in a little over 3 days. I have side effects of sulfur burps, dehydration, constant nausea, falling asleep at all times, all-night vomiting, and diarrhea. I feel bruised from head to toe and have blurred vision. I'm telling people this for a warning. Read the reviews. People are constantly going to the ER because of these medications. I'm flustered because I found something that worked for my diabetes, but it is really bad for me. Since starting Ozempic up to now, I've lost almost 30 lbs... might sound great, but not when you can't function."

• JWa...
• Taken for 1 to 6 months
• March 28, 2025

For Weight Loss (Obesity/Overweight) "Zepbound was effective within the first week. I experienced a significant decrease in hunger and decreased interest in food. I also found that I could not always finish a meal serving in one sitting. Initially, I had minor issues in bowel habits (constipation and diarrhea). Both symptoms are minor and managed with adequate hydration and fiber-rich foods. More disconcerting have been the “egg burps” caused by bacterial action on sulfur-rich foods in a slowed GI system. I have selected less sulfur-rich foods and make a concerted effort to drink more water during a day or two following the weekly injection. This side effect seems to have moderated, perhaps as I am into the second month of my current dosage and third month on Zepbound and/or temporarily minimizing sulfurous food intake in a short period following injection. I also track my food intake and assure I am eating an adequate level of protein. I have lost 15 pounds in 10 weeks. I am 77 and a woman."

• kim...
• Taken for 1 to 6 months
• September 13, 2022

For Type 2 Diabetes "I started out on the 5mg and was deathly ill from it for about a week, with severe diarrhea and belching that was so awful it made me want to vomit. I lost 9 pounds, and my sugars are going down and staying where they are supposed to be. I called my doctor, and she switched me down to the 2.5mg, better just one day of illness. Started back on the 5mg, and I still feel horrible for 24 hours after day 2 of the shot. But sugars are awesome, and I'm hoping this too will pass."

• SDG...
• Taken for less than 1 month
• September 21, 2022

For Type 2 Diabetes "I was prescribed the 2.5 dosage as a trial by my endocrinologist for pre-diabetic and weight loss on 9/15/22. I felt fine the first day, shot was given in the morning, but the next day I actually forgot to eat lunch. That is not normal for me. I wasn’t hungry. The third and fourth day I had horrible sulfur burps, nausea, fatigue. On the fourth day, I took two naps, which is not normal for me. I thought my symptoms were getting worse, but then the fifth and sixth day I felt great. I am fearful to take the next injection this week as I don’t want a repeat of the less than desirable side effects. It really wrecked my weekend. On the upside, I lost a couple of pounds the first week. That’s exciting, but at what cost?"

• MJC...
• Taken for 6 months to 1 year
• March 4, 2023

For Weight Loss (Obesity/Overweight) "Been on Mounjaro since 9/11/22. Today is 3/4/23. I have lost close to 60 lbs and went from a pant size 46 down to 40. My wife says I “lost my tire” looking at me from behind. Started at 2.5 dose. Was dizzy and unsteady in the early days. Headache and nausea till my body acclimated. Switched my shot day to Friday night so if I’m not feeling great, it’s the weekend and not impacting work. Worked up to 5.0 then 7.5. Did each for 8 weeks instead of 4 to level off the side effects. Wanted to stay at that level, but no one can get it. Took my first 10.0 shot last night. So far so good. All my levels are great. Sulfur burps if I overeat. Am also doing Herbalife shakes 2 times a day and having a sensible dinner. I still snack after dinner, but nothing crazy. Exercise 5/6 times per week. I think 7.5 should be my maintenance dose, but again, no one can get it. Will trade the mild side effects for being able to fit into my clothes."

• kto...
• Taken for 1 to 6 months
• November 7, 2022

For Type 2 Diabetes "I started Mounjaro 7 weeks ago. The first shot made me so nauseous and have such bad abdominal pain that lasted for 12 hours. I almost went to the ER. I told my doctor about my experience, and she gave me Zofran and told me to continue dieting. Fast forward to this weekend - took my shot on Friday morning, then spent all day Saturday and Sunday projectile vomiting (it literally ended up about 7 feet from where I was standing), uncontrollable diarrhea, disgusting sulfur burps, horrible heartburn, and dizziness. Finally, I decided to go to the ER and got treated for dehydration. They told me to follow up with my primary doctor to talk about the best way to continue the medication. After this experience, I am NEVER taking this drug again. While I've lost 25 lbs in the past 7 weeks, I believe it's mostly because I've been afraid to eat anything. I will continue to eat healthy and cut carbs and sugars, but I won't be taking Mounjaro again."

• Din...
• Taken for less than 1 month
• December 10, 2024

For Type 2 Diabetes "In the two doses, my blood sugar has been lower, my appetite has diminished, and I had no side effects. At the end of the second week (Saturday), I woke up during the night with stomach pain, diarrhea, and belching. After 6 hours, I finally vomited up undigested food that had been in my stomach for over 12 hours. It looked like I had just eaten. I avoided all food until Sunday morning, eating 1/2 of a plain English muffin. I had Lipton chicken soup, a piece of Bavarian pretzel, and a few french fries (picking from my wife’s meal). Monday, I finally felt hungry and had a Whopper Jr. (not a good choice I know), and Tuesday I woke up with food sitting in my stomach and one diarrhea BM. NOTE: I have not taken dose #3, nor do I plan to. This is slowing my digestion down too much. I have never had digestive issues, and I’m not going to start now."

• Bgd...
• Taken for 1 to 6 months
• October 27, 2024

For Weight Loss (Obesity/Overweight) "Outstanding! 59 yr old male. Started this journey at 251 lb. Just wrapping up the first month of 2.5 mg and have already dropped 15 lb! Down to 236! Moving to the 5 mg next week and cannot wait to keep moving forward! Other than a few extra burps, no side effects to speak of! The cost is an issue until I hit my deductible (as I have a high deductible plan), but if I am gonna meet the deductible, it may as well be sooner rather than later! This stuff is a game changer! No longer constantly thinking about the next meal!"

• Anonymous
• Taken for less than 1 month
• February 13, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "Started on Zepbound 2 weeks ago. I have only lost 2 pounds. I don’t feel like eating. At first, I was so tired, and that subsided. My biggest problem is the belching. I can’t seem to get rid of it."

• WVN...
• Taken for 1 to 6 months
• December 27, 2022

For Type 2 Diabetes "I started on the 2.5 dose in October, my doctor felt that the weight loss would help with my joint pain and lower my A1C. From day 1, I was extremely nauseous, had no desire to eat, had sulfur burps, and had constipation. I spoke with my doctor, who encouraged me to ride it out. On week four, I was stepped up to the 5 mg dosage. The doctor called in Zofran for stomach issues. On week six, I called her and said I could no longer function. During this time, I was so fatigued and was having heart palpitations and was barely able to walk 20 feet without being totally exhausted. I chalked it up to being so nauseous and not eating. Then my legs started to burn like I had walked up a steep hill and felt so sore and bruised I could barely sit. That week, I had my follow-up appointment with my doctor. I told her about my symptoms, and she said that rhabdomyolysis is not a side effect of Mounjaro. I was never dehydrated, but my CK levels were still 440 two weeks off the medication! Eight weeks later, and no improvement!"

• Far...
• Taken for 6 months to 1 year
• January 29, 2025

For Weight Loss (Obesity/Overweight) "I’ve lost 60 pounds on Zepbound and maintain the same lifestyle as before, with the exception that I don’t think about eating much and sometimes have to be intentional about eating anyway. My side effects are minimal, just sulfur burps on an increased dose, but generally disappear after a while. I take Pepto to help with that. I lost weight steadily in the beginning and slowed down after 6 months. I’m one year into it and still not down to where I want to be, 20 more pounds to go."

• WE...
• Taken for less than 1 month
• November 8, 2022

For Type 2 Diabetes "Went to the doctor and asked for something to help lose weight. He prescribed this medication. Day 1 and 2... nothing. Day 3 woke up with horrible heartburn and sour sulfur burps and facts and was constipated. By day 3 evening, I no longer had constipation but just the opposite... diarrhea! And not just any kind, it was like yellow water and very acidic. It hurt! Had horrible gas and belching all day Saturday, and Sunday couldn't hardly leave the bathroom to go buy Imodium. Imodium helped with that, but the gas is now trapped, and my stomach hurts badly, and I am full of gas with bad heartburn and belching. I saw a correlation between fatty foods and severe side effects of this product. But unless you're a vegan, you eat fat, and that's a major problem with this product. It is now Monday night, and I cannot seem to get my work done, I hurt so badly. I will never take this product again, and I cannot in good conscience recommend it with all the terrible side effects. Shame on Mounjaro!"

• WE...
• Taken for less than 1 month
• November 8, 2022

For Type 2 Diabetes "Went to the doctor and asked for something to help lose weight. He prescribed this medication. Day 1 and 2... nothing. Day 3 woke up with horrible heartburn and sour sulfur burps and facts and was constipated. By day 3 evening, I no longer had constipation but just the opposite... diarrhea! And not just any kind, it was like yellow water and very acidic. It hurt! Had horrible gas and belching all day Saturday, and Sunday couldn't hardly leave the bathroom to go buy Imodium. Imodium helped with that, but the gas is now trapped, and my stomach hurts badly, and I am full of gas with bad heartburn and belching. I saw a correlation between fatty foods and severe side effects of this product. But unless you're a vegan, you eat fat, and that's a major problem with this product. It is now Monday night, and I cannot seem to get my work done, I hurt so badly. I will never take this product again, and I cannot in good conscience recommend it with all the terrible side effects. Shame on Mounjaro!"