Skip to main content

Tirzepatide User Reviews & Ratings (Page 5)

Brand names: Mounjaro, Zepbound

Tirzepatide has an average rating of 8.6 out of 10 from a total of 1,040 reviews on Drugs.com. 81% of reviewers reported a positive experience, while 7% reported a negative experience.

Reviews for Tirzepatide

  • 1lilm...
  • Taken for 1 to 2 years
  • April 14, 2024

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "I just wanted to give an update on my success on Mounjaro. I've been on it for 18 months. I continue to lose weight slowly. No problem with the shot. I've lost a total of 118 pounds. I went from a size 22 to a size 2. I do Weight Watchers app online for the accountability. And walk 5-8 miles a day. My doctor thinks I should be her spokesperson in her office for the new patients going on it to give them the motivation. But can't with HIPAA. I'm okay with her giving them my name and everything but she can't. It's funny when I'm out in public and people are not sure if it's me or not. But it sure makes me feel good. I just know when people do ask how I've lost weight and I tell them. I say with diet, exercise, and I have diabetes. I also take Mounjaro but it's not a miracle drug."

Was this helpful?YesNo
16 Report
  • Ang
  • Taken for 1 to 6 months
  • December 6, 2022

Mounjaro (tirzepatide) for Diabetes, Type 2 "This is my fifth week and I started on 2.5mg and now on 5.0mg, I have had only one side effect. Dry mouth but I lost 29lbs the first month. I weighed 243lbs and now I am down to 214lbs. If you don’t eat fried foods, sugar, or heavy carbs, you will do great. I don’t overeat anymore, plus exercise I walk 5 miles a day. I drink at least 64fl oz water. This medication is worth taking. I had no issues at all. And feel great. I can’t wait to fulfill my journey. The key is to follow a plan. You want a life change this is it! I used the coupon and only certain pharmacies know how to code it. I got lucky because My pharmacy worked with me."

10 / 10
Was this helpful?YesNo
61 Report
  • Sarah
  • Taken for less than 1 month
  • September 13, 2022

Mounjaro (tirzepatide) for Diabetes, Type 2 "Constant nausea no matter what I eat. Muscle weakness and tired all the time. I’m feeling mentally down. Tomorrow will be my 3rd shot and I’m seriously hoping these side effects go away so I can get type II diabetes under control. Probably losing some weight because I dread the nausea after eating so am not eating as much. The verdict is still out for me on this medicine."

7 / 10
Was this helpful?YesNo
67 Report

Frequently asked questions

  • Jovanna
  • Taken for less than 1 month
  • March 22, 2023

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "So far, it's been great, no side effect whatsoever. I could say I'm not hungry at all, I eat out of habit but very little amount of food. Since I'm not hungry it allows me to make better food selections."

10 / 10
Was this helpful?YesNo
52 Report
  • Kate
  • Taken for 6 months to 1 year
  • July 11, 2024

Zepbound (tirzepatide) for Weight Loss (Obesity/Overweight) "Zepbound (tirzepatide) is amazing - if you are not losing much on semaglutide, see if your doctor will let you try tirzepatide. I’ve been on Zepbound seven months and I’m down 55 pounds. Took 2.5mg the first month and then spent 5 months on 5mg. Just moved up to 7.5mg this month and it has totally killed my appetite. Main side effect for me is fatigue, especially the day of the shot and the next couple of days. I plan to stay on 7.5 until I reach my goal weight and then go on maintenance. I will have to keep taking it - otherwise it is likely I will gain all the weight back. Yes, it is expensive but worth it."

10 / 10
Was this helpful?YesNo
3 Report

Are you taking this medicine?

  • Tracy
  • Taken for 1 to 6 months
  • August 19, 2023

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "I am just starting week 5. I started on 5mg, so today was my first 7.5. Last month, I lost exactly 20 pounds. I started at 222 and now I'm at 202 after 1 month. I get bad constipation, but nothing Dulcolax liquid can't fix. I drink 2 protein shakes a day, a handful of chicken, and some days I replace chicken with fruits and low-fat cottage cheese. I drink lots of water and have 1 coffee with only milk once a week. I can't wait until this time next month. It's definitely a game changer. I haven't been that active, but today I will start going to the gym 5 days a week. I will update next month."

10 / 10
Was this helpful?YesNo
38 Report
  • Lesso...
  • November 18, 2022

Mounjaro (tirzepatide) for Diabetes, Type 2 "I saw this medication on TikTok & decided to try it. Started on 2.5mg on 9/23/22 at 204 pounds. Had some chills & started feeling a little off, light headed, metallic taste in mouth, major loss of appetite, increased anxiety. Continued through the 2.5mg then moved up to 5.0mg. On my 4th injection of 5.0mg my life flipped upside down. This medication caused me some serious side effects, syncope, dehydration, electrolytes to be out of sync, chest pain & one heck of panic attack while at work I had to be rushed to ER. Very scary & thankful I was not driving when it happened. I've stopped the medication immediately. I want to feel normal again. Down to 190 pounds now not worth the risk."

1 / 10
Was this helpful?YesNo
59 Report

More FAQ

  • Mark
  • Taken for 1 to 6 months
  • May 25, 2024

Zepbound (tirzepatide) for Weight Loss (Obesity/Overweight) "Started using Zepbound in March 2024, at 2.5 mg. History of Obesity (BMI > 29) and Hypertension. Starting weight was 202 lb. and Blood Pressure Avg. of 153/90. As of today, May 24, 2024, currently on 10mg. My weight is currently 177 lb, having lost 25 lbs (12%) of starting weight. It was easy to learn how to use the injection pen, and it is a painless process. I am also exercising, running 4-5 days per week and weight training 2 days per week. Exercise is an important adjunct to weight loss treatment, and can help maintain muscle mass while losing weight. It is also imperative to eat foods rich in protein and green, leafy vegetables. Side effects have been minimal, with occasional constipation, which is remedied by using Miralax or similar products."

10 / 10
Was this helpful?YesNo
10 Report
  • chubs...
  • Taken for 1 to 6 months
  • June 1, 2024

Zepbound (tirzepatide) for Weight Loss (Obesity/Overweight) "5’ 8” and 272 was my starting stats. I did four weeks of 2.5 then went up to 5.0. I am only on my 6th week (4 2.5s and 2 5.0s) and I have already lost 30 pounds. Now, at 242, I am looking to take off another 30-50 pounds. I am trying to be put on a list to have a transplant and have to lose a certain amount of weight to make the list. I give the medication a 100% A+. If you need to drop weight, this is a great medication. Side effects: Constipation. Drink as much water as you can and be prepared to take laxatives to poo. I’m talking rock pebbles harder than pleasing a Gold-digger on a date; you’ll definitely have to take some laxatives to poo. I suggest flavoring your water. It helps. Candy: You will crave sugary candy like Gobstoppers, Sour Patch Kids, Skittles; pretty much anything you can get your hands on. Try dark chocolate almonds and just small nibbles of candy when you get really, really sleepy. Bottom line: It works! It's worth the hard rock poo."

10 / 10
Was this helpful?YesNo
9 Report
  • Tpott
  • Taken for 1 to 6 months
  • March 3, 2024

Zepbound (tirzepatide) for Weight Loss (Obesity/Overweight) "50-year-old female with 100 lbs to lose and PCOS. Been on Zepbound for 6 weeks (just took 7th shot). Minimal side effects. Occasional nausea, headaches, and sore muscles, usually the day after injection, but they go away by the next day. Taking the 5 mg dose right now. I have been getting large injection site rashes with itching, burning, and swelling with the last 3 doses. The swelling and itching go down after 3-4 days, but the red spots are still visible from all 3 of the previous doses. I didn't get this with the 2.5mg dose at all. Hoping it was just this last box of the medicine and the next will be better. I have only lost 5 lbs in the 6 weeks I have been on it, which has been very disappointing. It has lowered my blood pressure though. It was on the high side of normal before, now it's perfect. Really hoping that going up to the 7.5mg dose will start having better results for me as I have got a long way to go, and hopefully the skin reactions won't get worse."

7 / 10
Was this helpful?YesNo
19 Report
  • Ang
  • Taken for 1 to 6 months
  • March 2, 2023

Mounjaro (tirzepatide) for Diabetes, Type 2 "This is my 2nd post, I am on 7.5 mg of Mounjaro and I have loved every moment of this journey. I was 243 lbs and lost 49 lbs so far since October 2022. I also eat a healthy diet and exercise. Stay hydrated because my side effect is dry mouth and constipation. I did however find out that if you eat carbs, sugar, or fried food you will get nauseous and possibly throw up. Lesson learned. Stick to protein and vegetables and fruit. I need to lose 34 more lbs to be at my ideal weight. I am still excited to be on this journey."

10 / 10
Was this helpful?YesNo
49 Report
  • sherri
  • Taken for 1 to 6 months
  • March 18, 2024

Zepbound (tirzepatide) for Weight Loss (Obesity/Overweight) "I have been on Zepbound for two months and have lost only 9 pounds. I don't eat breakfast because I am not hungry; this has been a lifelong habit of mine. I am hungry at noon and eat more than I should. I have found that I am eating too fast, which is causing me to not have the weight loss that I would have if I ate slower. I have noticed that when I eat slower, I stop eating when I am halfway done with my meal. Hopefully, I can break a lifelong habit of eating fast. I have no side effects from the drug or overeating."

4 / 10
Was this helpful?YesNo
17 Report
  • Patti
  • Taken for 1 to 6 months
  • April 24, 2024

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "I have been losing about 2 lbs per week since I started using this. I was 170 lbs when I started and am down to 149 lbs over a period of 10 weeks. I was on the 2.5 mg for the first 4 weeks and then increased to 5 mg after that. It has taken away the 'food noise' where I am no longer preoccupied with what I'm going to eat and when. I have had a major decrease in appetite and there are days when I will only have a milkshake and not be hungry for anything else."

10 / 10
Was this helpful?YesNo
13 Report
  • Anonymous
  • Taken for 1 to 6 months
  • July 19, 2024

Zepbound (tirzepatide) for Weight Loss (Obesity/Overweight) "16 weeks now on Zepbound. I am down 27 lbs. 5’5’ 170 lbs now 143 lbs. Had high cholesterol. This is a great product but you have to be ready to eat healthy too. Protein shake in the am. Protein bar in the afternoon. Try Fuffil bars. Walmart sells them; they are amazing. Salads, salmon, pork, chicken, veggies for dinner. Try Sobol; they have a great green smoothie and healthy fruit options. Kodiak products are good too. No side effects, but I chose to stay at 5 mg. No need to go up. I have so much energy now; work out 6 days a week. It’s a new me, and I’m loving it."

10 / 10
Was this helpful?YesNo
1 Report
  • Shoor...
  • Taken for 1 to 6 months
  • April 25, 2023

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "This medication is incredible. My cholesterol and blood pressure were borderline. My doctor suggested losing weight (I have had a weight problem my entire life) which was an ongoing life pursuit for me. Nothing lasted. I would end up feeling worthless and depressed. I started this medication in January 2023. Today is April 25th and I have lost 36 pounds. My blood pressure is on its way down. My energy levels were stable throughout the day from week one so it is not just the weight loss, the medicine has helped with my ADHD and my depression. The only side effect I have experienced was constipation which I corrected by using small dosages of Miralax daily. I hope the FDA approves this medication for weight loss soon. It is a great tool to use along with healthy eating and exercise."

10 / 10
Was this helpful?YesNo
43 Report
  • Kim
  • Taken for 1 to 6 months
  • March 28, 2023

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "I feel amazing on Mounjaro. I feel as though my body is “back in tune” and the weight comes off steadily. I’m just never hungry but I do eat. It doesn’t take much for me to feel full once I do eat. 23 pounds lighter and 10 more to go."

10 / 10
Was this helpful?YesNo
45 Report
  • richard
  • Taken for less than 1 month
  • May 26, 2024

Zepbound (tirzepatide) for Weight Loss (Obesity/Overweight) "So, I took one dose; unfortunately, my doctor screwed up and started me at 15mg. I've been in the ED for 36 hours and have had the worst 3 weeks of my life. This is not a review but a caution; check your script thoroughly, make sure you're taking the right dose. I need to purge this dose from my system and then start a 2.5mg dose."

10 / 10
Was this helpful?YesNo
9 Report
  • Paul
  • Taken for 1 to 2 years
  • June 27, 2023

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "I seem to have experienced almost every side effect except coma, and if I hadn't stopped taking the drug, I'm certain that my severe jaundice would have put me in a coma. I did lose a significant amount of weight but almost died in the process, and my tachycardia is still presenting..."

1 / 10
Was this helpful?YesNo
38 Report
  • MTOG
  • Taken for 6 months to 1 year
  • May 14, 2023

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "This medication has been a huge blessing in my life. Started at the lowest dose in August of 2022. Increased each month to the highest dose and have stayed there for 3 months now. It's May of 2023, and I have lost 80 pounds!! I was pre-diabetic, depressed, and hopeless. I've had a bit of stomach upset, diarrhea, heartburn, gas...nothing terrible. But I feel so much better. My joints don't hurt hardly at all, I have more confidence to go places and talk to people and do stuff outside and I even sleep better. I was looking into bariatric surgery before I found Mounjaro. I'm so glad I didn't have to do that."

9 / 10
Was this helpful?YesNo
41 Report
  • Dawn
  • Taken for less than 1 month
  • March 18, 2024

Zepbound (tirzepatide) for Weight Loss (Obesity/Overweight) "Started Zepbound 2.5 mg just 3 days ago. For the first time in my LIFE, I am eating to nourish my body, and not to satisfy hunger or cravings! Super excited to see how the weight will drop with new habits. Downside, I wasted a pen the very first time I injected because I didn't remove the grey closure. My fault for not thoroughly following the instructions but total bummer because the cost of this med is not cheap and the pharmacy says they can't fill an Rx for just one pen. It would be nice if the manufacturer of the drug would allow a single pen to be purchased for a lesser cost."

8 / 10
Was this helpful?YesNo
16 Report
  • Alve
  • Taken for less than 1 month
  • September 3, 2022

Mounjaro (tirzepatide) for Diabetes, Type 2 "I don’t have diabetes. I may have insulin resistance. I’m taking this for weight loss. BMI 48. Took first dose, a sample dose, five days ago. I didn’t even feel the needle. Within a day of the injection I started having pain in my low back, in the tailbone area, squeezing muscle pain when standing or walking. The pain goes away after a few minutes of sitting or lying down. (I had similar pain when taking Belviq. I don’t normally have back pain.) Also have some intermittent mild itching at wrists, ankles. I still think about food all the time but I’m not actually interested in eating it. Someone brought me a quarter pounder sandwich for supper. I had to cut it in half and then I shared my half with the cat. There’s cake in the refrigerator and I haven’t touched it. I’m hungriest in the mid-morning now and today had 1 low carb tortilla, one link turkey sausage, a slice of cheese, cilantro, and a bowl of watermelon."

8 / 10
Was this helpful?YesNo
56 Report
  • Maryan
  • Taken for less than 1 month
  • January 4, 2024

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "I've been taking Mounjaro 2.5mg for 3 weeks now, and have lost a total of 22 lbs. When they say it kills the appetite, they aren't kidding! I struggle to get 800 calories a day, and most of the time, those are either from salad dressings or protein shakes. The side effects aren't horrible, just not fun either. The first 3 days after my shot, I've got constipation and no appetite at all, those are the days when I'll have a single 32 mg protein shake for the day - if I take in anything else, I feel like I've overeaten and get bloated and slightly nauseous - not worth it. Day 4 I start to feel really queasy and can't even stomach my shake. Day 5 comes the diarrhea, for the entire day. Day 5 and 6 I feel pretty good. I know it's a lot, but the symptoms haven't really caused me to do anything different - other than consumption of food. I live off of Gin-Gin chews (ginger chews) for the symptoms, and they are enough to keep everything at a low-grade annoyance."

10 / 10
Was this helpful?YesNo
22 Report
  • Dory
  • Taken for 6 months to 1 year
  • March 31, 2023

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "Mounjaro has been a life saver for me. I am fortunate enough to not have many side effects. In the beginning I would get gas and stomach cramping, but I have learned what foods seem to cause that and now avoid them. It is so nice to be able to get through the day with my brain not constantly telling me to eat."

10 / 10
Was this helpful?YesNo
42 Report
  • Skinny...
  • Taken for 6 months to 1 year
  • October 9, 2023

Mounjaro (tirzepatide) for Weight Loss (Obesity/Overweight) "I am 74 years old. I was thin until I was 40. Started eating all the wrong food as my husband showed his love with food. I started Mounjaro last year in October. I didn't lose any weight for the first 2 months. I lost 5 lbs in the third month. Then I started losing more. I went from 175 to 115 by August. I never wake up at night and started having a problem making it to the bathroom to pee 3 times a week. I called my doctor and she lowered my Mounjaro dosage to 10 mg and I was fine. I stopped taking Mounjaro last month. Mounjaro makes you just not hungry. I learned to be picky about what I ate. I chose healthy food and feel lighter. I have learned to be healthy and thin. Yes, I am short at 5ft 3 inches and happy to have taken Mounjaro."

10 / 10
Was this helpful?YesNo
28 Report
  • ssram
  • Taken for 1 to 2 years
  • June 22, 2024

Mounjaro (tirzepatide) for Diabetes, Type 2 "My question is if a medication such as Mounjaro helps and works and allows a patient to live an almost normal life but cannot afford to pay for it, how come Eli Lilly is so adamant about helping a senior on Medicare to pay for this medication. How about offering a reasonable discount so that I can continue buying it so I do not face hypo no hyperglycemia? Is my health not worth it vs. the CEO and the rest of the top management to get their big bonuses? Really! Patients need help, please. Medicare patients are not allowed to use savings cards, only commercial medical insurance. Please think about this issue and help us to live a better and decent life. I am not obese, nor do I need it for weight loss. I need it to maintain my health. Thank you in advance should you find it in your heart to help me with my costs. I was diagnosed with CKD, and after I started using Mounjaro, my kidneys numbers went up significantly so did my diabetes being more manageable. Thank you again."

10 / 10
Was this helpful?YesNo
5 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.