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Sofosbuvir / velpatasvir User Reviews & Ratings (Page 2)

Brand names: Epclusa

Sofosbuvir / velpatasvir has an average rating of 7.8 out of 10 from a total of 408 reviews on Drugs.com. 66% of reviewers reported a positive experience, while 12% reported a negative experience.

Reviews for Sofosbuvir / velpatasvir

  • Anonymous
  • Taken for 1 to 6 months
  • April 14, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "65-year-old Geno 3. It is 6 months since I finished Epclusa, and I have a loss of hearing in my right ear, nausea, numb fingers, and can't sleep. I got rid of the virus, but I really did feel better BEFORE I did the treatment. Liver clinic and doctors are no help whatsoever, no one seems to know anything except that these horrible feelings won't be going away, and I feel like a guinea pig. I can't get any help, no one cares. Gilead makes money. I had this treatment here in Australia."

1 / 10
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  • Mary
  • Taken for 1 to 6 months
  • December 15, 2021

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I thought my 12-week treatment on Epclusa was going really hard on me. Apparently, I had had Hep C in my body with no symptoms for 45 years from a blood transfusion. Was tested for it in routine tests and then had a liver biopsy, which showed only level one liver damage. I had, during treatment, and still suffer from extreme fatigue, memory issues, and insomnia. If I had ever dreamed how my life would change for the worse, I would never have taken the first pill! The only positive is that I am now free of Hep C, which I had apparently had for 45 years without symptoms. I am 79 years old and believe I could have lived the remaining years of my life without Epclusa!"

3 / 10
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  • Havoc
  • Taken for less than 1 month
  • July 19, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "This is my 2nd week on Epclusa. I caught the disease early with no liver scarring. I was terrified to begin treatment regardless of the positive reviews. The 1st week was rough but nothing compared to the free life I am headed towards. Day 1, nothing. Days 2 + 3 I had such unbearable fatigue and weakness I could hardly walk and required help from my family to get through the day. I was concerned that would be my life for the rest of the treatment and was afraid. Day 4 I spontaneously recovered but I was still weak, not alert. Day 4+ I RAPIDLY improved. Yesterday I felt better than even before I had started the medication, 0 side effects OR symptoms. I have night sweats but those are disappearing. I haven’t had nausea or headache, have had slight diarrhea. Those two days of despair were a small price to pay for the freedom I will get. Don’t fret about starting this medication. The first pill is your ticket to your new beginning."

8 / 10
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Frequently asked questions

  • Emmyy
  • July 29, 2022

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Hey I started taking this drug Epclusa in June 2022 diagnosed & started this drug. 2 weeks in blood test show negative, great, but noticed straight away I had a weird heart beat on taking it, a high blood pressure feeling. Also feeling sick gradually went off food lost my appetite, so lost weight. By the way I’m half way thru and I still have no appetite I’m still loosing weight. I get severe headaches and sickness so feel like I’m loosing my mind. Also aches, pains, joint pain, head pain ,back pain, sore throat. I feel like absolute rubbish. I can not understand the weight loss I’ve been reading thru these and not once seen weight loss am I the only one ? Anyway point is I feel like I’m dying"

5 / 10
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  • Mandy
  • Taken for 1 to 6 months
  • February 9, 2020

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I’m almost 12 weeks on Epclusa, and to say it’s been hard would be an understatement. I’ve been beyond tired, I’ve tried taking the medication both in the morning and at night. I’ve found that at night works best for me. I’ve become extremely irritable and depressed. I’ve also recently had this weird hormonal issue where my boobs hurt, and I have acne (not even close to having my period nor pregnant). I never got any headaches or ear ringing, so that’s a plus. I know it’s all going to be worth it in the end, and I would not have done things any differently. For those of you reading through hundreds of reviews, like myself—know that it will get better. I also have to take it for 3 months due to having type 3. Cheers to being hep C free. I received the medication for free through Support Path, also Gilead. Look into it if you don’t have insurance!"

6 / 10
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Are you taking this medicine?

  • Valerie
  • Taken for 1 to 6 months
  • December 29, 2021

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I am 62 years old and haven't used I.V. drugs since I was 22. Recently found out I have been infected with Hep C for 40 years. I had no symptoms but after 3 tests I chose Epclusa. Did not have any side effects at all. No headaches no nausea no bowel changes no fatigue. I had strain 1a and 1b with a viral load of 18 million. The doctor called me on the phone and said I am cured that no virus is detected in my blood. Unfortunately, my stomach is noticeably bloated and hard up high. I can't eat much at all or it will bloat to the point of pain. I am also making clay colored bowel motions occasionally which is both a symptom of liver disease and hep c. I felt fine before I took this medicine now I feel like I've done damage to my liver. I really don't believe I'm cured.I feel like there was no point in taking this medicine. I felt better and looked better before I took it."

5 / 10
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  • jjjj
  • Taken for 1 to 6 months
  • March 19, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I completed the 3 months of Epclusa treatment in December 2018 for my Hep C. It is now March 2019, and the side effects are worse now. I have constant buzzing in my head/ears (tinnitus), numbness and tingling, internal shakiness, insomnia, brain fog, feeling very weak, depression, and back pain. I regret taking Epclusa. I felt better before the treatment. I have gone to a naturopathic practitioner, chiropractor, and acupuncturist to try to help, but it is not any better. I don't know what to do at this point, and it is scary."

1 / 10
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More FAQ

  • Jonny
  • Taken for 1 to 6 months
  • August 1, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I took my last pill today after completing 3 months. I had HCV genotype 3 for about 27 years. During treatment, I felt tired in the afternoon and after doing any exercise. I'd take a nap for a few hours, then I'd feel pretty good. No tinnitus, but sometimes when relaxing, I'd feel numbness in my hands or fingers. It didn't last long. Overall, I am very happy with Epclusa. Prior to treatment, I'd read all these horrible stories about side effects. Thankfully, whatever side effects I had were not too bad. My blood work at 4 weeks came back as virus undetected, so after 2 more months on the medication, I am hoping that all the little hiders have been destroyed."

10 / 10
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  • Wacka...
  • April 22, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I finished Epclusa two weeks ago. I've had gum pain and pain in my legs since. I'm glad to be completed. I'm not sure why everyone keeps leaving reviews only a few weeks into treatment. My side effects varied weekly, so I couldn't really give a review while taking the drug. I also have a ringing sound in my head all day, every day, and no hearing loss. I hope that goes away with time. Undetected since week 4. I'd like to hear from others who are months into recovery after this. Do you feel better? Did your side effects go away?"

5 / 10
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  • Moni
  • Taken for 1 to 6 months
  • April 11, 2021

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Just started my third month of Epclusa. So far, not much of side effects. A little anxiety or irritation at times. No nausea, diarrhea, or anything like that so far. My doctor won’t test until a few weeks after the final dose is taken. I did notice after the first four weeks I have much more energy and not feeling so depressed anymore. I will update again once I’ve finished taking the medication and after I’ve been tested again for viral detection."

9 / 10
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  • rudone
  • Taken for 1 to 6 months
  • February 11, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I am 71, I have had Hep C for who knows how long. I did the interferon/procrit six years ago - don't do it, it doesn't work, and the side effects are psychologically and physically destructive. It can lead to suicidal depression. I had two friends die on it. It has been 90 days since treatment with Epclusa, and no virus is detected."

10 / 10
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  • Lizzy...
  • Taken for 1 to 6 months
  • August 21, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I'm 2 weeks off of finishing the Epclusa drug. I'm so exhausted all the time. I hurt all over, even doing nothing leaves me in physical pain and physically exhausted. I was not sick before I started, but have been sick since the first tablet. I have headaches, weird dreams, pain in my feet, pain in my legs, pain in my back. Sleeping only helps for a couple of hours, can barely leave the house. If this doesn't work, I'm never going to take anything else."

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  • Kat
  • Taken for 1 to 6 months
  • September 14, 2018

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Today, 31 days after starting this wonderful drug, my lab test came back 'Not Detectable.' I have had Hep C for 53 years, without knowing it for 52 years due to a blood transfusion in 1965. I have had no side effects. My advice to everyone that is starting it: Drink at least 100 ounces of water every day, limit caffeine, fake sugars, and spicy stuff. Coffee, hot sauce, and Splenda were aggravating my tinnitus, and cutting back fixed it. Best of luck to everybody, and thank you, Gilead, for developing this drug! You saved my life!"

10 / 10
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  • Smitty
  • July 26, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Took Epclusa for a 90-day course of treatment, fatigue, brain fog, lethargy, moody, lots of anxiety. 30-day blood work showed no Hep C. 2 weeks till I get final blood work done. Hopefully, I’m cured. Still tired and lethargic but not as bad. I’m 64 years old and am glad I did it. Don’t let the side effects hold you back or scare you. Just suck it up and do it. Price is frikkin' outrageous but I got help from a grant from the PAN organization. There’s financial help out there. If you wanna be cured, do it!"

10 / 10
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  • Madei...
  • Taken for less than 1 month
  • April 21, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "So, I began taking this medication for Hep C contracted from IV drug use. 24 years old. Doctor explained that since I had PPO insurance they would most likely cover the cost of the medication, which I believe goes for around 75k for a 3-month supply. The medication was delivered straight to my house. Genotype 2b. Viral load was 1.7 million initially. I started taking the medication on March 30th, 2017. I had labs done this week to check on progress. After just 21 days of taking Epclusa, viral load is completely undetectable. Initial fatigue first week, no symptoms after that. Great medication! Grateful that this option was available to me. Was absolutely worth it!"

10 / 10
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  • Say
  • Taken for 1 to 6 months
  • September 17, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I was taking it in the morning, and that isn’t a good idea. I felt sick all day long 'til about 4 PM, then I got my energy back, so I take it at night now. I do have insomnia, but it’s getting better. I started it on Aug 19, 2019. The brain fog is getting worse as I take the medication. Drink lots of water or I get a sick feeling and nauseous. My joint pain and fatigue are better. My eyes turn blue about 20 minutes after taking the medication, and I get this odd feeling all through my body after I take it. I only say it’s like you feel the medication working on fighting the virus. I have had depression just start 9-10-2019. I can say I feel more there except when the brain fog kicks in, and I have serious worry it won’t go away. My lymph nodes are swollen, but they are going down. I’m glad I finally got to fight this virus, I honestly can’t wait for these 12 weeks to be over."

6 / 10
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  • Jules
  • September 14, 2020

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I caught Hep C about 11 years ago from a BF when I was an active IV heroin addict. When I found out and told my BF, he just said I FIGURED YOU ALREADY DID, BECAUSE I'M SURE I DO. Well, thank you so much! For the next 12 years, I didn't give a second thought to the Hep C or what it was doing to me. I am now coming up on my 3-year sobriety anniversary! My mom has been on me about starting Hep C treatment. So I did. I found out today that I will be taking Epclusa. I'm really scared about the possible side effects. I was recently married and have a 17-month-old son too. I'm so worried about side effects and how I will take care of my son when my husband isn't home. I have had some side effects from the Hep C, like an enormous protruding stomach, and my entire body is constantly bloated. My feet and ankles look worse than when I was pregnant. My hands get so swollen I can hardly bend my fingers. I get numb toes too. I really hope this medication will cure me of Hep C and help with my other problems from it. Wish me luck!"

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  • Jesst...
  • Taken for 1 to 6 months
  • September 26, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Hi...So I took 12 weeks of Epclusa for genotype 3a (viral load-3 million). The Epclusa did do the trick to get rid of the Hep C; however, I did experience and still do experience side effects. While I was on treatment, I experienced tingling, nerve pain, irritability, insomnia, ear ringing, etc. The ear ringing and ear issues remain a problem after 7 months off of the meds. I urge everyone to report side effects to the FDA. When I reported them to my doctor, I was told NO ONE else had those side effects...and I felt like I was crazy. The only way they will have a list of the accurate side effects is if they are reported to the FDA and Gilead. This helps other patients not feel so alone. All in all, it solved the main issue I suppose--"

8 / 10
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  • Skpp
  • Taken for 1 to 6 months
  • March 26, 2018

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Ruined my life, feel like I'm dying every day. Don't believe all these miracle stories you read. It's been over a year for me now, and I'm getting worse every day. Even the people that had no side effects when taking it are now showing up down the road."

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  • exhau...
  • August 14, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "Was diagnosed four months ago with Hep C, it was a complete shock. Terrified, but my doctor assured me it would be fine in time. The medication at first caused extreme fatigue, restlessness, and inability to sleep. Late in the day, I would feel more energetic, so I began to take my medication at 8 PM to sleep through side effects. It helped tremendously. I returned to almost normal levels of energy. I am four weeks post-treatment, terrified because I am so exhausted that doing ADLs is about all that I can manage most days. I am terrified that the treatment was more destructive to my body than the disease. My review is mixed, my viral load is undetectable, that is success."

8 / 10
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  • Marc...
  • December 11, 2017

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I'm a 62-year-old man with Hep C type 2b. I have had Hep C for over 40 years from IV drug use in the early 1970s. I got sober in AA in 1977 and was diagnosed with Hep C shortly afterwards. I annually would get my blood work tested and in 2010 had stage 3 cirrhosis. In 2014, my insurance covered a 90-day Hep C treatment with Sovaldi and Ribavirin. I had a difficult time, after 60 days, Hep C was undetected. However, 90 days after the conclusion, the Hep C returned! Fast forward to today, I have 25 days left on the Epclusa 90-day treatment plan. I am still Hep C detected, from 1.5 million to 85, however, still detected. My doctor is not optimistic, and I am frustrated but still trying. I am not giving up hope, please pray for me! Thank you."

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  • Anonymous
  • July 2, 2020

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I have now completed Epclusa! I am 2 months post treatment! I am still NEGATIVE! So it does work! I wanted to share my experience because some of you who are concerned about the side effects should be! Yes, I am treated, but now the COVID is going around. I have been left with near to no immune system to fight anything else off! I don't know for sure the Epclusa did this. But I got a yeast infection during treatment, probably from the Epclusa, and fought for 2 months to get rid of it. I ended up at my doctor after test results from the past 3 months of blood work from 3 different docs. I have found out my WBC is down to a 4 and has remained there since I completed treatment. I am now susceptible to catching basically anything and having no immune system left to fight it off. During treatment, I did not sleep for 3 months! I lost 20 pounds, was left with migraines every night, night sweats, and the list goes on. I am still weak every day in my arms and legs!"

5 / 10
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  • Geezer
  • Taken for 1 to 6 months
  • February 27, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I started on Epclusa 5 weeks ago. I was really nervous about side effects. As it turned out, I didn't have any. Nothing. I have a viral load of 6 million. My fibroscan was a 4.6, so my liver is in better shape than even most people that don't have Hep C. The beginning of fatty infiltration. Genotype 1a. My ALTs were 400 when I started, my 4-week ALT was 19. So far, so good. Hoping for the best. Don't be afraid of this miracle. Genotype 1a."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • November 4, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "First couple of days on Epclusa, I had joint pain in elbows and knees. Mild headache in the mornings. Energy same. Week 3, now experiencing swollen neck glands and sore throat. Drinking 4 bottles of water daily. I also take medication before bed. Please share your experience. There's not a lot of info, and the experts are very vague about side effects."

7 / 10
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  • Grate...
  • September 20, 2019

Epclusa (sofosbuvir / velpatasvir) for Hepatitis C "I’m on my fourth day. So far, no side effects, no headache, fatigue, nausea, insomnia, or diarrhea, nothing. I put this off after my trip thinking I was going to feel terrible after reading all the reviews. Maybe it’s too soon to tell, I’ll update later."

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.