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Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 5)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 7.3 out of 10 from a total of 609 reviews for the treatment of Weight Loss (Obesity/Overweight). 63% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Semaglutide

  • GEF
  • Taken for 1 to 6 months
  • January 9, 2022

Wegovy (semaglutide) "I’ve been using Wegovy for 12 weeks. I’m up to 0.50 and staying here. Tried 1.0 and it was too strong. Felt nauseous and experienced painful stomach cramps with 1.0. I have reached my goal weight. I lost 35 pounds and I’m very happy with the process and results. The only negative is, I’m on thyroid medication and noticed hot flashes and heart palpitations I didn’t experience before. I had my levels checked and they are way off! Consulting with my doctor. Not sure if I’ll continue Wegovy."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 27, 2023

Ozempic (semaglutide) "I am just completed my first 2 weeks. I want to lose 35-40 pounds. In the past year, I have gained a pound a month and have been steadily gaining weight every year for the past 7 years. Have previously tried weight watchers, increased activity, and calorie watching, and the only time I lost any weight was on less than 1300 calories a day. The first week I lost 3.5 pounds, more weight than I had lost in the past 5 years even with calorie restricting. I inject in alternating thighs on Friday nights, just in case I have symptoms I can recover without work demands. I have always been gassy so cannot comment if there is a difference in the amount. I am noticing increased chest tenderness and muscle spasms. Restless legs are a thing! Taking magnesium once or twice a week also helps with moderate constipation. Reduced appetite, reduced sugar craving but no impact on munchies. Makes easier to choose healthier choices. Overall happy with almost 5-pound weight loss in 2 weeks. Minimal side effects and well worth it."

8 / 10
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  • Mcook
  • Taken for less than 1 month
  • April 4, 2024

Wegovy (semaglutide) "I took my first 0.25 shot of Wegovy 4 days ago. Everything is going great so far. I experience a very small amount of nausea in the morning but it is completely manageable. I have noticed that I am more content throughout the day and my portion sizes have gone down. I have also had a lot more energy and don’t feel so tired all the time. I know that it is very early to really give a review for this medication so this is more directed to those individuals who are nervous or scared to start the medication. I was terrified after reading some of the “bad” reviews but I finally did it. I know we will all have different experiences but it was definitely worth trying in my opinion!"

10 / 10
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Frequently asked questions

  • Mimi
  • Taken for 1 to 6 months
  • September 19, 2023

Wegovy (semaglutide) "Wegovy is working great! Very important to hydrate and have a lot of fiber. Also, control your portion size; you cannot eat large portions. I'm following a strict 1300 calorie lifestyle change. From June 17, 2023, to present (Sept 19, 2023), I've lost 30 lbs. The injections are simple and virtually painless. I'm currently on 1.7 and I have little to no side effects. I inject every Saturday night before I go to sleep. I read that taking medication before bed reduces nausea and for me, it has worked. The only side effect is that I have absolutely NO desire to drink alcohol. The best side effect ever! I've already stopped taking blood pressure medication, cholesterol medication has been reduced to the lowest dose, and my A1C is out of the pre-diabetic range and within normal limits, and I'm only halfway to my weight loss goal. All medication has been stopped or reduced by my physician after blood work. Very happy!"

10 / 10
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  • MM...
  • Taken for 1 to 6 months
  • December 22, 2022

Wegovy (semaglutide) "Wegovy has agonizing side effects. I had to quit after 2 months. Constant uncontrollable vomiting, I vomited at work, and while driving (which was horrific and dangerous). I essentially became bulimic, and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."

1 / 10
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Are you taking this medicine?

  • Anonymous
  • Taken for 1 to 6 months
  • November 7, 2023

Wegovy (semaglutide) "I love the effects of Wegovy, however, my stomach felt upset the whole time I took it. I lost a lot of weight, pretty quickly. It happened so fast; I could not keep up with clothing size changes. I lost about 50 pounds in 3 months. I tried to eat, but the weight kept coming off. I would recommend a probiotic to help with the stomach issues, but overall, I am happy with the experience."

9 / 10
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  • anxiety
  • Taken for less than 1 month
  • March 2, 2023

Wegovy (semaglutide) "I started taking Wegovy 2 weeks ago. The first week was okay but in the second week, I started experiencing really bad anxiety. I wish I could be like other people and just get regular side effects. So far I have lost 10 lbs."

8 / 10
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More FAQ

  • TED...
  • Taken for 6 months to 1 year
  • September 9, 2023

Ozempic (semaglutide) "I have been taking Ozempic for 9 months. I am 74 years old, and a workaholic. I simply do not have time to exercise. I am at my computer working between 18 and 20 hours x 7 x 365. This will not change - ever. I got up to 274 lbs. I weigh once weekly. Today I weighed 191 lbs., or a loss of 83 lbs. over the duration - or about 30% of my body weight. Some slight dizziness from time to time which has diminished considerably after the 2nd month. Bad diarrhea for 72 hours after each injection until I discovered this medication does not like fat/grease/fried food of any type - then, some manageable diarrhea thereafter. Dosage .5 mg. Extraordinarily easy to use."

10 / 10
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  • Mr B
  • Taken for 1 to 6 months
  • December 5, 2023

Wegovy (semaglutide) "I have lost 19 pounds in the first 4 weeks on 0.25 dosage. I have found that low-fat cottage cheese with some fruit is good around noon as a brunch, with a high-protein dinner and a small salad. I was 2 weeks in over Thanksgiving and was still able to enjoy most everything, but just in much smaller portions. Eating out, I order fish or chicken and ask for a box with the dinner and split it for leftovers. Absolutely no side effects - except for the first day each week after the shot, I find I burp after eating. Also, note: the effects start off very strong during the first part of the week and taper towards the end. I do find myself able to eat more on the last day before my next shot, but even still no major hunger pains. Eat high protein and low-fat, and drink lots of water. I weigh myself every morning and find I lose more on days I drink at least 50 or more ounces of water the previous day. My goal is to lose 40 pounds, and at this rate, I think it will only take me about 70 days. Best journey ever!"

10 / 10
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  • NursD...
  • Taken for 1 to 6 months
  • July 15, 2023

Ozempic (semaglutide) "Ozempic for weight loss is AMAZING! I have tried everything for weight loss since 1985. Ozempic by far is a miracle for me. It immediately blocks cravings, appetite, and thoughts about food! I started June 2, 2023 and today, July 13, 2023, I lost 22.3 lbs. This is a 6-week success story! I took 0.25 for the first week and then 0.5 weekly on Sundays. I have stayed with Weight Watchers, mainly selecting 'free foods'. If you are eating out with friends this summer, remember that rich, high-fat content foods will give you immediate abdominal distress (cramps, diarrhea). So, I've learned to go through restaurant menus and find something less distressful to eat so that I can enjoy time with friends and family. I have Zofran for nausea, but for me, the nausea passes and I do not use anything for nausea. Stay active at least walk! It's free! Keep drinking water and add a packet of electrolytes due to this extreme heat this summer! Check-in with my doctor on a regular basis."

10 / 10
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  • AMano
  • January 2, 2022

Wegovy (semaglutide) "I’m on Week 15 of treatment and have lost nothing. On the first dose of 0.75 mg I experienced heartburn, fullness, and zero appetite for 5 days. I was hopeful that it had finally started to work. On subsequent doses of 0.75 mg and 1 mg, and now on 1.7 mg I’ve felt no effects from Wegovy. I’ve tried switching injection sites from my abdomen to my arm with no effect."

1 / 10
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  • Barbi...
  • Taken for 1 to 6 months
  • March 24, 2023

Ozempic (semaglutide) "I have been taking Ozempic for six weeks. This will be my second week at .50 mg and I have lost 10 lbs. At .25 mg I had minor nausea and was very tired but felt fine otherwise. After my first .50 mg injections, I could not drink, eat or do anything for the first day. I had a lot of nausea and felt like I was going to be sick constantly. By day 3 I had to go to the bathroom about nine times which was good because constipation is a real thing with this medication. By day 4 and on I felt perfectly fine. I do watch what I eat and the medication has cut my food intake by half. You have to pay attention to what your stomach is telling you."

7 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • May 8, 2023

Ozempic (semaglutide) "I was prescribed Ozempic for weight loss in Nov 2022. I started on .25 mg for one month. I found it slightly suppressed my appetite and the side effects I had were awful heartburn, constipation, and sulphur burps. Sometimes I felt nauseous. I decided to stick with it anyway and increased to .5 mg after one month. The symptoms were the same but add in fatigue. A month later I bumped up to .75 and the burps, fatigue and heartburn subsided. I went to 1 mg 2 months later and all symptoms disappeared. I started at 192 lbs Nov 15th and as of May 1st I weigh 152 lbs. I found my sugar cravings disappeared once I started taking 1 mg. Up until then I still craved sugary foods. I lost all interest in greasy food ( fries, anything deep fried etc) from .5 mg and up. I personally love Ozempic. The side effects at the beginning were worth it for me but from the sounds of it, mine weren’t that bad. I have never once thrown up."

10 / 10
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  • Chris...
  • Taken for 1 to 6 months
  • May 11, 2024

Wegovy (semaglutide) "Personally, I would recommend Wegovy to anyone struggling with weight loss. I'm 6 months in, a 41-year-old man. My starting weight was 14 stone 9.5 lb, and I'm currently 13 stone 2.5 lb. I'll start with the negatives: 1. Cost - this is very expensive, especially at the top dose, which is what you'll likely stay on for the longest. 2. Side effects - everyone is different; for me, it was indigestion and occasional nausea, but it's been perfectly manageable and worth it considering the benefits of the weight loss. The positives: I rarely feel hungry; I often have to force myself to eat. My portion sizes are much smaller, and I no longer go for sweet treats before bed. I haven't altered my diet at all; I still eat unhealthy food when I want, just less of it, and less frequently, so I don't struggle with cravings for foods that I'm not allowed."

10 / 10
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  • XXO
  • Taken for less than 1 month
  • June 11, 2023

Ozempic (semaglutide) "I experienced vomiting within one hour, swelling of the throat, and difficulty swallowing which has not stopped since the first and last dose on Sept 6th, 2023. Now hypersensitive to all regular daily medications and am taking Benadryl several times per day."

1 / 10
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  • 1887 ...
  • Taken for 1 to 6 months
  • May 17, 2023

Wegovy (semaglutide) "Started Wegovy 3 months ago using the gradual phase-up method. From .25 mg dose for 4 weeks to .50 mg dose for 4 weeks then 1.0 mg dose for 4 weeks. During the initial phase, I experienced mild nausea and some stomach irritation. With each increase the symptoms got worse until finally at the full 1.0 mg dose I was so sick I thought I had stomach flu for 2 weeks continuously. The belching was horrible. The nausea caused uncontrollable vomiting and I had frequent diarrhea. After 3 months I lost 12 pounds and felt horrible every day. I've now reduced the dose to .5 mg but still suffer from nausea and stomach upset. I might cut back again but I'm thinking I will quit. The way I feel all the time is horrible!! I'm thinking I lost weight because of all the vomiting. Not recommended."

1 / 10
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  • Scott
  • Taken for less than 1 month
  • May 9, 2023

Wegovy (semaglutide) "Started with the .25mg dose and had very little side effects. A slight tiredness was felt but noticed immediately the reduce level of my appetite and hunger needs. I felt full sooner with smaller portions of food and had no cravings to nibble on stuff at night... which was the norm for me. Make sure to eat well with a basic caloric intake needed for your height and weight, drink plenty of fluids and get decent sleep daily. This along with a normal gym schedule works wonders! I have been on the medication for 5 days now and lost (I assume mostly water weight) 5 lbs in this short time period. I stay active which also helps with weight loss but have noticed a complete change in appetite and the lack of needing to snack during the day. I feel this plan will work for me in my goal to lose 20 lbs. and will help keep the weight off due to forcing a lifestyle change in my exercise and activity levels being increased. The key is having the desire for change and Wegovy assists in that."

9 / 10
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  • JAO
  • Taken for 1 to 6 months
  • June 14, 2023

Wegovy (semaglutide) "I had been on this drug for 4 months. Typical escalation dose until month 4 I stayed on the 1mg. The side effects were rough since increasing to 1mg. So much nausea, worsened reflux, constipation, bloating, burping, and indigestion. I vomited once but there were a few times I almost did. In the last few weeks, I noticed hair loss. Noticed skin tags that I have never had...like 3 grow since the med. Weird. Oh, and I had serious issues with certain smells. I had to change out the hand soaps in my house 5 times. If I smell rubbing alcohol I am instantly nauseous. Just looking at the wegovy box before injecting would make me dizzy and nauseous. So weird. Difficult to eat healthy on this med due to side effects and only able to tolerate simple carbs, low-fat diet. Also hard to work out when feeling so nauseous...so didn't think it was contributing to my health. Has not really contributed to weight loss and appetite is almost the same as before med."

1 / 10
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  • Tressa
  • Taken for less than 1 month
  • March 25, 2023

Wegovy (semaglutide) "I have been on this medication for one week. On the second day I was very tired, on days 3-6 I was nauseous the whole time. Every time I ate something other than toast or crackers, I had major cramping. Plus a mild headache all week. This was a horrible experience. The pain felt like a gallbladder attack. Never again."

1 / 10
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  • Super...
  • Taken for 6 months to 1 year
  • January 4, 2022

Wegovy (semaglutide) "Pros- I've been on Wegovy for 7 Months. it Started Working right away. Lost between 8-15 lbs. a month. it mostly has effected my appetite. (not feeling hungry). have lost 65 lbs. thus far Cons- nothing noticeable until I made it to the 1.7mg dosage and it got worse on the 2.4mg.. severe diarrhea and cramps a day after eating. I noticed this became more regular after the 2.4mg dosage. it happens 4-5 days after the injection only for it to clear up after I give myself the next injection. any Bismuth anti-diarrhea helps to clear this but you have to remember to take with with almost every meal."

7 / 10
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  • January
  • Taken for less than 1 month
  • January 9, 2023

Wegovy (semaglutide) "Took my first 0.25mg Wegovy dose yesterday. I felt nauseous about an hour later but within 2 hours I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

1 / 10
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  • Danie...
  • Taken for 1 to 6 months
  • April 5, 2023

Wegovy (semaglutide) "I wanted to warn people of the side effects as my doctor did not prepare me for this med. I am very glad I didn't try to work otherwise I would have lost my job or at the very least been written up for various reasons. On it for a month. I tried spacing out the second shot and never ended up taking the last injection. Side effects: Severe fatigue, severe hair loss, decreased hormones, severe headaches, changes in your sleep architecture, bad nightmares for all sleep, naps, and overnight. Warning if you have PTSD that may mess with you. Bladder urgency and uti symptoms started on day 3 and were constant the whole time on the med, had to take AZO. Bloating, burping, throwing up, and all food smells make you sick, severe constipation, hypoglycemia, and increased binge eating. I also had increased topical psoriasis and arthritis pain. Started having problems with my foot and wondering if impacting ligaments. I am getting that checked out. Did not reduce the need to eat, no weight loss."

1 / 10
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  • Penn
  • Taken for less than 1 month
  • October 31, 2022

Wegovy (semaglutide) "Don't use it !!! After having this I was in bed 6 days and had to go to hospital to get hydration due to risk of my kidneys I felt as though this was a poision going through my body and almost immediately nauseous and could not keep anything down Don't do it"

1 / 10
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  • Enigm...
  • Taken for less than 1 month
  • January 27, 2024

Wegovy (semaglutide) "I'm a newcomer. Been taking Wegovy for 4 weeks now, lost 4 kilos so far. My problem is my appetite & overeating. Wegovy is a Godsend, it completely eradicated my appetite, so I only eat 2 small meals a day. I combine this with reduced carbs & 16-hour IF. I aim to lose 20 kilos in 6 months, which sounds better than drastic, excessive weight loss too quickly. I'll keep you updated."

10 / 10
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  • Jenny
  • Taken for less than 1 month
  • January 3, 2022

Wegovy (semaglutide) "I started this weight loss journey with wegovy 4 days ago. No nausea but definitely have some diarrhea starting the second day. I will continue with the treatment unless the side effects change or worsen."

8 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.